SIMILAR PATTERN OF AMINO ACIDS MAPPED TO 'CT3'


List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TKQ_B_DVAB8_0
(GRAMICIDIN A)		 4doe 1,4-BETA-GLUCANASE
(Caldicellulosiru
ptor
bescii) 		4 / 5 VAL A 423
GLY A 424
VAL A 444
TRP A 334
 None
None
None
CT3  A 504 (-3.9A)
 1.26A 1tkqB-4doeA:
undetectable		 1tkqB-4doeA:
3.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3A_A_TEPA1434_1
(CHITINASE)		 4doe 1,4-BETA-GLUCANASE
(Caldicellulosiru
ptor
bescii) 		3 / 3 TRP A 281
THR A 173
TYR A 220
 CT3  A 504 ( 4.0A)
CA  A 502 ( 4.5A)
None
 1.18A 2a3aA-4doeA:
undetectable		 2a3aA-4doeA:
23.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3A_B_TEPB2434_1
(CHITINASE)		 4doe 1,4-BETA-GLUCANASE
(Caldicellulosiru
ptor
bescii) 		3 / 3 TRP A 281
THR A 173
TYR A 220
 CT3  A 504 ( 4.0A)
CA  A 502 ( 4.5A)
None
 1.20A 2a3aB-4doeA:
undetectable		 2a3aB-4doeA:
23.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3B_A_CFFA1434_1
(CHITINASE)		 4doe 1,4-BETA-GLUCANASE
(Caldicellulosiru
ptor
bescii) 		3 / 3 TRP A 281
THR A 173
TYR A 220
 CT3  A 504 ( 4.0A)
CA  A 502 ( 4.5A)
None
 1.22A 2a3bA-4doeA:
undetectable		 2a3bA-4doeA:
23.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PCL_B_SAMB301_0
(O-METHYLTRANSFERASE
FAMILY PROTEIN)		 3voh CELLOBIOHYDROLASE
(Coprinopsis
cinerea) 		5 / 12 LEU A 322
GLY A 254
ASN A 294
ALA A 213
ASN A 214
 None
None
CT3  A1002 (-3.9A)
None
CT3  A1002 ( 4.9A)
 1.37A 4pclB-3vohA:
undetectable		 4pclB-3vohA:
20.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B1E_B_LF7B801_1
(DIPEPTIDYL PEPTIDASE
4)		 4yhg GH5
(Bacteroidetes
bacterium
AC2a) 		5 / 12 ARG A  67
GLU A 168
TYR A 251
ASN A 171
HIS A 111
 None
None
CT3  A 401 (-4.4A)
CT3  A 401 (-3.1A)
CT3  A 401 (-4.2A)
 1.49A 6b1eB-4yhgA:
undetectable		 6b1eB-4yhgA:
19.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6C2M_C_SUEC1203_1
(NS3 PROTEASE)		 4doe 1,4-BETA-GLUCANASE
(Caldicellulosiru
ptor
bescii) 		5 / 9 VAL A 284
HIS A 285
GLY A 287
LEU A  95
ASP A 447
 None
None
None
None
CT3  A 504 ( 4.5A)
 1.23A 6c2mC-4doeA:
undetectable		 6c2mC-4doeA:
9.23