SIMILAR PATTERN OF AMINO ACIDS MAPPED TO 'CS4'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1H7X_A_URFA1033_1 (DIHYDROPYRIMIDINE DEHYDROGENASE)	2oqz	SORTASE B (Bacillus anthracis)	4 / 6	ASN A 102 ILE A 192 ASN A 134 ASN A 126	CS4 A 233 ( 4.1A) None None None	1.21A	1h7xA-2oqzA: undetectable	1h7xA-2oqzA: 11.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1H7X_B_URFB1033_1 (DIHYDROPYRIMIDINE DEHYDROGENASE)	2oqz	SORTASE B (Bacillus anthracis)	4 / 6	ASN A 102 ILE A 192 ASN A 134 ASN A 126	CS4 A 233 ( 4.1A) None None None	1.21A	1h7xB-2oqzA: undetectable	1h7xB-2oqzA: 11.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1H7X_C_URFC1033_1 (DIHYDROPYRIMIDINE DEHYDROGENASE)	2oqz	SORTASE B (Bacillus anthracis)	4 / 6	ASN A 102 ILE A 192 ASN A 134 ASN A 126	CS4 A 233 ( 4.1A) None None None	1.20A	1h7xC-2oqzA: undetectable	1h7xC-2oqzA: 11.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1H7X_D_URFD1033_1 (DIHYDROPYRIMIDINE DEHYDROGENASE)	2oqz	SORTASE B (Bacillus anthracis)	4 / 6	ASN A 102 ILE A 192 ASN A 134 ASN A 126	CS4 A 233 ( 4.1A) None None None	1.20A	1h7xD-2oqzA: undetectable	1h7xD-2oqzA: 11.93

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1H7X_A_URFA1033_1","DIHYDROPYRIMIDINE DEHYDROGENASE","2oqz","SORTASE B","Bacillus anthracis",4,"ASN A 102;ILE A 192;ASN A 134;ASN A 126","CS4 A 233 ( 4.1A);None;None;None","1.21A","1h7xA-2oqzA:undetectable",null],["1H7X_B_URFB1033_1","DIHYDROPYRIMIDINE DEHYDROGENASE","2oqz","SORTASE B","Bacillus anthracis",4,"ASN A 102;ILE A 192;ASN A 134;ASN A 126","CS4 A 233 ( 4.1A);None;None;None","1.21A","1h7xB-2oqzA:undetectable","1h7xA-2oqzA:11.93"],["1H7X_C_URFC1033_1","DIHYDROPYRIMIDINE DEHYDROGENASE","2oqz","SORTASE B","Bacillus anthracis",4,"ASN A 102;ILE A 192;ASN A 134;ASN A 126","CS4 A 233 ( 4.1A);None;None;None","1.20A","1h7xC-2oqzA:undetectable","1h7xB-2oqzA:11.93"],["1H7X_D_URFD1033_1","DIHYDROPYRIMIDINE DEHYDROGENASE","2oqz","SORTASE B","Bacillus anthracis",4,"ASN A 102;ILE A 192;ASN A 134;ASN A 126","CS4 A 233 ( 4.1A);None;None;None","1.20A","1h7xD-2oqzA:undetectable","1h7xC-2oqzA:11.93"]]