SIMILAR PATTERN OF AMINO ACIDS MAPPED TO 'CRQ'


List of Similar Pattern of Amino Acids


Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DZ9_A_CAMA503_0
(CYTOCHROME P450-CAM)
2c9j GREEN FLUORESCENT
PROTEIN FP512

(Cerianthus
membranaceus)
4 / 8 PHE A  38
LEU A 196
THR A  42
VAL A  12
CRQ  A  62 ( 3.6A)
CRQ  A  62 ( 4.2A)
None
None
1.09A 1dz9A-2c9jA:
undetectable
1dz9A-2c9jA:
20.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQB_A_GLYA1292_0
(SERINE
HYDROXYMETHYLTRANSFE
RASE)
2ib5 CHROMO PROTEIN
(Epiactis
japonica)
4 / 8 HIS A 197
SER A 195
TYR A 178
PHE A  80
CRQ  A  65 ( 3.7A)
None
None
None
1.16A 1eqbA-2ib5A:
undetectable
1eqbB-2ib5A:
undetectable
1eqbA-2ib5A:
19.95
1eqbB-2ib5A:
19.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQB_A_GLYA1292_0
(SERINE
HYDROXYMETHYLTRANSFE
RASE)
4zb1 BLUE CHROMOPROTEIN,
SGBP

(Stichodactyla
gigantea)
4 / 8 HIS A 196
SER A 194
TYR A 177
PHE A  79
CRQ  A  62 ( 3.7A)
None
None
None
1.13A 1eqbA-4zb1A:
undetectable
1eqbB-4zb1A:
undetectable
1eqbA-4zb1A:
19.43
1eqbB-4zb1A:
19.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQB_B_GLYB2292_0
(SERINE
HYDROXYMETHYLTRANSFE
RASE)
2ib5 CHROMO PROTEIN
(Epiactis
japonica)
4 / 8 TYR A 178
PHE A  80
HIS A 197
SER A 195
None
None
CRQ  A  65 ( 3.7A)
None
1.19A 1eqbA-2ib5A:
undetectable
1eqbB-2ib5A:
undetectable
1eqbA-2ib5A:
19.95
1eqbB-2ib5A:
19.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQB_B_GLYB2292_0
(SERINE
HYDROXYMETHYLTRANSFE
RASE)
4zb1 BLUE CHROMOPROTEIN,
SGBP

(Stichodactyla
gigantea)
4 / 8 TYR A 177
PHE A  79
HIS A 196
SER A 194
None
None
CRQ  A  62 ( 3.7A)
None
1.15A 1eqbA-4zb1A:
undetectable
1eqbB-4zb1A:
undetectable
1eqbA-4zb1A:
19.43
1eqbB-4zb1A:
19.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQB_C_GLYC3292_0
(SERINE
HYDROXYMETHYLTRANSFE
RASE)
2ib5 CHROMO PROTEIN
(Epiactis
japonica)
4 / 8 HIS A 197
SER A 195
TYR A 178
PHE A  80
CRQ  A  65 ( 3.7A)
None
None
None
1.17A 1eqbC-2ib5A:
undetectable
1eqbD-2ib5A:
undetectable
1eqbC-2ib5A:
19.95
1eqbD-2ib5A:
19.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQB_C_GLYC3292_0
(SERINE
HYDROXYMETHYLTRANSFE
RASE)
4zb1 BLUE CHROMOPROTEIN,
SGBP

(Stichodactyla
gigantea)
4 / 8 HIS A 196
SER A 194
TYR A 177
PHE A  79
CRQ  A  62 ( 3.7A)
None
None
None
1.14A 1eqbC-4zb1A:
undetectable
1eqbD-4zb1A:
undetectable
1eqbC-4zb1A:
19.43
1eqbD-4zb1A:
19.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQB_D_GLYD4292_0
(SERINE
HYDROXYMETHYLTRANSFE
RASE)
2ib5 CHROMO PROTEIN
(Epiactis
japonica)
4 / 8 TYR A 178
PHE A  80
HIS A 197
SER A 195
None
None
CRQ  A  65 ( 3.7A)
None
1.18A 1eqbC-2ib5A:
undetectable
1eqbD-2ib5A:
undetectable
1eqbC-2ib5A:
19.95
1eqbD-2ib5A:
19.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQB_D_GLYD4292_0
(SERINE
HYDROXYMETHYLTRANSFE
RASE)
4zb1 BLUE CHROMOPROTEIN,
SGBP

(Stichodactyla
gigantea)
4 / 8 TYR A 177
PHE A  79
HIS A 196
SER A 194
None
None
CRQ  A  62 ( 3.7A)
None
1.15A 1eqbC-4zb1A:
undetectable
1eqbD-4zb1A:
undetectable
1eqbC-4zb1A:
19.43
1eqbD-4zb1A:
19.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IOL_A_ESTA400_1
(ESTROGENIC 17-BETA
HYDROXYSTEROID
DEHYDROGENASE)
2c9j GREEN FLUORESCENT
PROTEIN FP512

(Cerianthus
membranaceus)
5 / 11 VAL A  12
GLY A  27
LEU A  40
GLY A 116
GLU A 212
None
None
CRQ  A  62 ( 4.6A)
None
CRQ  A  62 ( 3.4A)
1.38A 1iolA-2c9jA:
undetectable
1iolA-2c9jA:
20.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IVV_A_DAHA382_1
(AMINE OXIDASE)
5y00 GREEN FLUORESCENT
PROTEIN

(Olindias)
5 / 10 TYR A 115
THR A 100
ASP A 183
VAL A 186
HIS A  74
CRQ  A  70 ( 4.4A)
None
None
None
CRQ  A  70 ( 4.1A)
1.30A 1ivvA-5y00A:
undetectable
1ivvA-5y00A:
6.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IVV_B_DAHB382_1
(AMINE OXIDASE)
5y00 GREEN FLUORESCENT
PROTEIN

(Olindias)
5 / 10 TYR A 115
THR A 100
ASP A 183
VAL A 186
HIS A  74
CRQ  A  70 ( 4.4A)
None
None
None
CRQ  A  70 ( 4.1A)
1.28A 1ivvB-5y00A:
undetectable
1ivvB-5y00A:
6.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MAA_B_DMEB996_1
(ACETYLCHOLINESTERASE)
3adf MONOMERIC AZAMI
GREEN

(Galaxea
fascicularis)
4 / 6 TYR A  87
GLU A 144
ILE A 118
TYR A 116
None
None
None
CRQ  A  64 ( 4.6A)
1.06A 1maaB-3adfA:
undetectable
1maaD-3adfA:
undetectable
1maaB-3adfA:
15.84
1maaD-3adfA:
15.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MAA_B_DMEB996_1
(ACETYLCHOLINESTERASE)
3cgl GFP-LIKE FLUORESCENT
CHROMOPROTEIN
DSFP483

(Discosoma
striata)
4 / 6 TYR A  91
GLU A 148
ILE A 122
TYR A 120
None
None
None
CRQ  A  66 ( 4.5A)
1.09A 1maaB-3cglA:
undetectable
1maaD-3cglA:
undetectable
1maaB-3cglA:
16.70
1maaD-3cglA:
16.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MAA_B_DMEB996_1
(ACETYLCHOLINESTERASE)
4jc2 ASFP504
(Alcyonium)
4 / 6 TYR A  87
GLU A 144
ILE A 118
TYR A 116
None
CRQ  A  64 ( 4.9A)
None
CRQ  A  64 ( 4.6A)
1.04A 1maaB-4jc2A:
undetectable
1maaD-4jc2A:
undetectable
1maaB-4jc2A:
16.76
1maaD-4jc2A:
16.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MAA_B_DMEB996_1
(ACETYLCHOLINESTERASE)
4tza FLUORESCENT PROTEIN
(synthetic
construct)
4 / 6 TYR C  87
GLU C 144
ILE C 118
TYR C 116
None
CRQ  C  62 ( 4.8A)
None
CRQ  C  62 ( 4.7A)
1.12A 1maaB-4tzaC:
undetectable
1maaD-4tzaC:
undetectable
1maaB-4tzaC:
15.88
1maaD-4tzaC:
15.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NOD_B_H4BB902_1
(NITRIC OXIDE
SYNTHASE)
4jc2 ASFP504
(Alcyonium)
3 / 3 ARG A  66
ILE A 107
TRP A  89
CRQ  A  64 ( 4.3A)
None
CRQ  A  64 ( 3.9A)
1.09A 1nodB-4jc2A:
undetectable
1nodB-4jc2A:
19.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NX9_A_AICA5001_1
(ALPHA-AMINO ACID
ESTER HYDROLASE)
2ib5 CHROMO PROTEIN
(Epiactis
japonica)
4 / 8 GLN A 106
HIS A 197
SER A 195
TYR A  72
CRQ  A  65 ( 4.1A)
CRQ  A  65 ( 3.7A)
None
None
1.34A 1nx9A-2ib5A:
undetectable
1nx9A-2ib5A:
16.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NX9_A_AICA5001_1
(ALPHA-AMINO ACID
ESTER HYDROLASE)
4zb1 BLUE CHROMOPROTEIN,
SGBP

(Stichodactyla
gigantea)
4 / 8 GLN A 105
HIS A 196
SER A 194
TYR A  71
CRQ  A  62 ( 4.0A)
CRQ  A  62 ( 3.7A)
None
None
1.25A 1nx9A-4zb1A:
undetectable
1nx9A-4zb1A:
15.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NX9_B_AICB5002_1
(ALPHA-AMINO ACID
ESTER HYDROLASE)
4zb1 BLUE CHROMOPROTEIN,
SGBP

(Stichodactyla
gigantea)
4 / 8 GLN A 105
HIS A 196
SER A 194
TYR A  71
CRQ  A  62 ( 4.0A)
CRQ  A  62 ( 3.7A)
None
None
1.25A 1nx9B-4zb1A:
undetectable
1nx9B-4zb1A:
15.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NX9_C_AICC5003_1
(ALPHA-AMINO ACID
ESTER HYDROLASE)
2ib5 CHROMO PROTEIN
(Epiactis
japonica)
4 / 8 GLN A 106
HIS A 197
SER A 195
TYR A  72
CRQ  A  65 ( 4.1A)
CRQ  A  65 ( 3.7A)
None
None
1.33A 1nx9C-2ib5A:
undetectable
1nx9C-2ib5A:
16.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NX9_C_AICC5003_1
(ALPHA-AMINO ACID
ESTER HYDROLASE)
4zb1 BLUE CHROMOPROTEIN,
SGBP

(Stichodactyla
gigantea)
4 / 8 GLN A 105
HIS A 196
SER A 194
TYR A  71
CRQ  A  62 ( 4.0A)
CRQ  A  62 ( 3.7A)
None
None
1.24A 1nx9C-4zb1A:
undetectable
1nx9C-4zb1A:
15.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NX9_D_AICD5004_1
(ALPHA-AMINO ACID
ESTER HYDROLASE)
2ib5 CHROMO PROTEIN
(Epiactis
japonica)
4 / 8 GLN A 106
HIS A 197
SER A 195
TYR A  72
CRQ  A  65 ( 4.1A)
CRQ  A  65 ( 3.7A)
None
None
1.33A 1nx9D-2ib5A:
undetectable
1nx9D-2ib5A:
16.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NX9_D_AICD5004_1
(ALPHA-AMINO ACID
ESTER HYDROLASE)
4zb1 BLUE CHROMOPROTEIN,
SGBP

(Stichodactyla
gigantea)
4 / 8 GLN A 105
HIS A 196
SER A 194
TYR A  71
CRQ  A  62 ( 4.0A)
CRQ  A  62 ( 3.7A)
None
None
1.24A 1nx9D-4zb1A:
undetectable
1nx9D-4zb1A:
15.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PG2_A_ADNA552_1
(METHIONYL-TRNA
SYNTHETASE)
4zb1 BLUE CHROMOPROTEIN,
SGBP

(Stichodactyla
gigantea)
5 / 11 GLY A 218
HIS A 192
GLU A 144
HIS A 196
VAL A 217
None
None
CRQ  A  62 ( 3.5A)
CRQ  A  62 ( 3.7A)
None
1.13A 1pg2A-4zb1A:
undetectable
1pg2A-4zb1A:
19.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QZR_B_CDXB901_2
(DNA TOPOISOMERASE II)
2ib5 CHROMO PROTEIN
(Epiactis
japonica)
4 / 7 THR A 108
TYR A 117
ASN A  61
LEU A  13
None
CRQ  A  65 ( 4.1A)
None
None
1.12A 1qzrB-2ib5A:
undetectable
1qzrB-2ib5A:
20.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RQP_A_SAMA500_1
(5'-FLUORO-5'-DEOXYAD
ENOSINE SYNTHASE)
3ir8 LARGE STOKES SHIFT
FLUORESCENT PROTEIN

(Montipora
sp.
20)
4 / 7 PHE A  79
TRP A  89
SER A 175
ARG A  91
None
None
None
CRQ  A  64 ( 2.8A)
1.28A 1rqpB-3ir8A:
undetectable
1rqpB-3ir8A:
19.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T86_A_CAMA1422_0
(CYTOCHROME P450-CAM)
1mov GFP-LIKE
NON-FLUORESCENT
CHROMOPROTEIN

(Montipora
efflorescens)
4 / 8 TYR A 181
THR A 179
THR A  73
VAL A 195
None
CRQ  A  66 ( 4.7A)
None
None
0.93A 1t86A-1movA:
undetectable
1t86A-1movA:
17.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T9W_A_NFNA6001_1
(ACRIFLAVINE
RESISTANCE PROTEIN B)
3ir8 LARGE STOKES SHIFT
FLUORESCENT PROTEIN

(Montipora
sp.
20)
3 / 3 SER A 175
GLY A 155
ARG A 193
None
None
CRQ  A  64 ( 4.2A)
0.67A 1t9wA-3ir8A:
undetectable
1t9wA-3ir8A:
11.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TUV_A_VK3A4558_1
(PROTEIN YGIN)
3cgl GFP-LIKE FLUORESCENT
CHROMOPROTEIN
DSFP483

(Discosoma
striata)
4 / 7 TYR A  91
LEU A 113
TYR A 120
ILE A   8
None
None
CRQ  A  66 ( 4.5A)
None
1.16A 1tuvA-3cglA:
undetectable
1tuvA-3cglA:
17.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UYU_A_CAMA1416_0
(CYTOCHROME P450-CAM)
2c9j GREEN FLUORESCENT
PROTEIN FP512

(Cerianthus
membranaceus)
4 / 8 PHE A  38
LEU A 196
THR A  42
VAL A  12
CRQ  A  62 ( 3.6A)
CRQ  A  62 ( 4.2A)
None
None
1.10A 1uyuA-2c9jA:
undetectable
1uyuA-2c9jA:
20.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UYU_B_CAMB1416_0
(CYTOCHROME P450-CAM)
2c9j GREEN FLUORESCENT
PROTEIN FP512

(Cerianthus
membranaceus)
4 / 8 PHE A  38
LEU A 196
THR A  42
VAL A  12
CRQ  A  62 ( 3.6A)
CRQ  A  62 ( 4.2A)
None
None
1.07A 1uyuB-2c9jA:
undetectable
1uyuB-2c9jA:
20.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XDK_B_9CRB600_2
(RETINOIC ACID
RECEPTOR, BETA)
1mov GFP-LIKE
NON-FLUORESCENT
CHROMOPROTEIN

(Montipora
efflorescens)
3 / 3 LEU A  54
PHE A  27
ARG A  95
None
None
CRQ  A  66 ( 2.9A)
0.89A 1xdkB-1movA:
undetectable
1xdkB-1movA:
19.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XDK_B_9CRB600_2
(RETINOIC ACID
RECEPTOR, BETA)
2c9i GREEN FLUORESCENT
PROTEIN ASFP499

(Anemonia
sulcata)
3 / 3 LEU A  51
PHE A  24
ARG A  92
None
None
CRQ  A  63 ( 3.1A)
0.83A 1xdkB-2c9iA:
undetectable
1xdkB-2c9iA:
20.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XDK_B_9CRB600_2
(RETINOIC ACID
RECEPTOR, BETA)
2h8q RED FLUORESCENT
PROTEIN DRFP583

(Discosoma
sp.)
3 / 3 LEU A  54
PHE A  27
ARG A  95
None
None
CRQ  A  66 ( 3.0A)
0.85A 1xdkB-2h8qA:
undetectable
1xdkB-2h8qA:
20.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XDK_B_9CRB600_2
(RETINOIC ACID
RECEPTOR, BETA)
2vad RED FLUORESCENT
PROTEIN

(Discosoma
sp.)
3 / 3 LEU A  54
PHE A  27
ARG A  95
None
None
CRQ  A  66 ( 2.9A)
0.88A 1xdkB-2vadA:
undetectable
1xdkB-2vadA:
18.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XDK_B_9CRB600_2
(RETINOIC ACID
RECEPTOR, BETA)
3cgl GFP-LIKE FLUORESCENT
CHROMOPROTEIN
DSFP483

(Discosoma
striata)
3 / 3 LEU A  54
PHE A  27
ARG A  95
None
None
CRQ  A  66 ( 3.0A)
0.90A 1xdkB-3cglA:
undetectable
1xdkB-3cglA:
23.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JFA_B_RALB600_1
(ESTROGEN RECEPTOR)
3adf MONOMERIC AZAMI
GREEN

(Galaxea
fascicularis)
5 / 12 GLU A 211
ARG A  66
MET A  14
GLY A  27
LEU A  42
CRQ  A  64 ( 4.0A)
CRQ  A  64 ( 3.8A)
None
None
None
0.92A 2jfaB-3adfA:
undetectable
2jfaB-3adfA:
20.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V7U_B_SAMB1299_1
(5'-FLUORO-5'-DEOXY
ADENOSINE SYNTHETASE)
3ir8 LARGE STOKES SHIFT
FLUORESCENT PROTEIN

(Montipora
sp.
20)
4 / 7 PHE A  79
TRP A  89
SER A 175
ARG A  91
None
None
None
CRQ  A  64 ( 2.8A)
1.30A 2v7uB-3ir8A:
undetectable
2v7uB-3ir8A:
19.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZT7_A_GLYA1300_0
(GLYCYL-TRNA
SYNTHETASE)
4zb1 BLUE CHROMOPROTEIN,
SGBP

(Stichodactyla
gigantea)
4 / 7 TYR A 177
ARG A 146
GLU A 144
SER A 157
None
None
CRQ  A  62 ( 3.5A)
CRQ  A  62 ( 2.5A)
1.27A 2zt7A-4zb1A:
undetectable
2zt7A-4zb1A:
15.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CCF_B_BEZB261_0
(CYCLOPROPANE-FATTY-A
CYL-PHOSPHOLIPID
SYNTHASE)
3cgl GFP-LIKE FLUORESCENT
CHROMOPROTEIN
DSFP483

(Discosoma
striata)
4 / 8 ASN A 109
ILE A 111
PHE A  72
TYR A 120
CRQ  A  66 ( 4.1A)
None
None
CRQ  A  66 ( 4.5A)
1.14A 3ccfB-3cglA:
undetectable
3ccfB-3cglA:
22.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_L_TFPL201_1
(PROTEIN S100-A4)
5y00 GREEN FLUORESCENT
PROTEIN

(Olindias)
4 / 7 GLY A  37
PHE A  87
PHE A  73
PHE A  47
None
None
CRQ  A  70 ( 3.8A)
CRQ  A  70 ( 4.7A)
1.04A 3ko0L-5y00A:
undetectable
3ko0N-5y00A:
undetectable
3ko0L-5y00A:
21.90
3ko0N-5y00A:
21.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_M_TFPM201_1
(PROTEIN S100-A4)
2c9j GREEN FLUORESCENT
PROTEIN FP512

(Cerianthus
membranaceus)
4 / 7 GLY A  27
PHE A  79
PHE A  65
GLY A  30
None
None
CRQ  A  62 ( 3.7A)
None
0.97A 3ko0M-2c9jA:
undetectable
3ko0P-2c9jA:
undetectable
3ko0M-2c9jA:
20.90
3ko0P-2c9jA:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_P_TFPP201_1
(PROTEIN S100-A4)
2c9j GREEN FLUORESCENT
PROTEIN FP512

(Cerianthus
membranaceus)
4 / 7 PHE A  65
GLY A  30
GLY A  27
PHE A  79
CRQ  A  62 ( 3.7A)
None
None
None
0.91A 3ko0M-2c9jA:
undetectable
3ko0P-2c9jA:
undetectable
3ko0M-2c9jA:
20.90
3ko0P-2c9jA:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LN1_D_CELD682_2
(PROSTAGLANDIN G/H
SYNTHASE 2)
2c9j GREEN FLUORESCENT
PROTEIN FP512

(Cerianthus
membranaceus)
4 / 5 LEU A  40
ARG A  66
ILE A 107
PHE A  65
CRQ  A  62 ( 4.6A)
CRQ  A  62 ( 4.0A)
None
CRQ  A  62 ( 3.7A)
1.23A 3ln1D-2c9jA:
0.0
3ln1D-2c9jA:
16.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V4T_A_ACTA503_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)
4tza FLUORESCENT PROTEIN
(synthetic
construct)
3 / 3 ARG C 194
GLU C 211
THR C  37
None
CRQ  C  62 ( 3.5A)
None
0.88A 3v4tA-4tzaC:
undetectable
3v4tA-4tzaC:
19.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DO3_A_0LAA602_1
(FATTY-ACID AMIDE
HYDROLASE 1)
5y00 GREEN FLUORESCENT
PROTEIN

(Olindias)
4 / 5 LEU A  69
LEU A  24
MET A  60
THR A 111
CRQ  A  70 ( 4.3A)
None
None
None
1.42A 4do3A-5y00A:
undetectable
4do3A-5y00A:
9.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EOH_B_TEPB402_1
(PYRIDOXAL KINASE)
2ib5 CHROMO PROTEIN
(Epiactis
japonica)
4 / 5 SER A  83
TYR A  79
VAL A  67
ASP A  78
None
None
CRQ  A  65 ( 4.8A)
None
1.18A 4eohB-2ib5A:
undetectable
4eohB-2ib5A:
20.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EOH_B_TEPB402_1
(PYRIDOXAL KINASE)
4zb1 BLUE CHROMOPROTEIN,
SGBP

(Stichodactyla
gigantea)
4 / 5 SER A  82
TYR A  78
VAL A  66
ASP A  77
None
None
CRQ  A  62 ( 4.8A)
None
1.11A 4eohB-4zb1A:
undetectable
4eohB-4zb1A:
23.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IJI_H_BEZH501_0
(GLUTATHIONE
S-TRANSFERASE-LIKE
PROTEIN YIBF)
4jc2 ASFP504
(Alcyonium)
4 / 7 ASN A 195
ALA A  59
VAL A 157
ARG A  91
CRQ  A  64 ( 3.3A)
CRQ  A  64 ( 3.9A)
None
CRQ  A  64 ( 3.0A)
1.14A 4ijiH-4jc2A:
undetectable
4ijiH-4jc2A:
19.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K38_B_SAMB504_0
(ANAEROBIC
SULFATASE-MATURATING
ENZYME)
2vad RED FLUORESCENT
PROTEIN

(Discosoma
sp.)
5 / 12 PHE A  56
GLN A 213
LEU A  46
VAL A  48
ILE A  29
None
CRQ  A  66 ( 3.8A)
None
None
None
1.14A 4k38B-2vadA:
undetectable
4k38B-2vadA:
20.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K39_A_SAMA504_0
(ANAEROBIC
SULFATASE-MATURATING
ENZYME)
2h8q RED FLUORESCENT
PROTEIN DRFP583

(Discosoma
sp.)
5 / 12 PHE A  56
GLN A 213
LEU A  46
VAL A  48
ILE A  29
None
CRQ  A  66 ( 3.9A)
None
None
None
1.23A 4k39A-2h8qA:
undetectable
4k39A-2h8qA:
21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K39_A_SAMA504_0
(ANAEROBIC
SULFATASE-MATURATING
ENZYME)
2vad RED FLUORESCENT
PROTEIN

(Discosoma
sp.)
5 / 12 PHE A  56
GLN A 213
LEU A  46
VAL A  48
ILE A  29
None
CRQ  A  66 ( 3.8A)
None
None
None
1.22A 4k39A-2vadA:
undetectable
4k39A-2vadA:
20.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L9Q_A_9TPA601_1
(SERUM ALBUMIN)
3adf MONOMERIC AZAMI
GREEN

(Galaxea
fascicularis)
5 / 12 LEU A  42
ALA A 103
TYR A 116
ILE A  10
GLY A  31
None
None
CRQ  A  64 ( 4.6A)
None
None
1.35A 4l9qA-3adfA:
undetectable
4l9qA-3adfA:
16.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L9Q_A_9TPA601_1
(SERUM ALBUMIN)
4tza FLUORESCENT PROTEIN
(synthetic
construct)
5 / 12 LEU C  42
ALA C 103
TYR C 116
ILE C  10
GLY C  31
None
None
CRQ  C  62 ( 4.7A)
None
None
1.32A 4l9qA-4tzaC:
undetectable
4l9qA-4tzaC:
18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L9Q_B_9TPB601_1
(SERUM ALBUMIN)
4tza FLUORESCENT PROTEIN
(synthetic
construct)
5 / 12 LEU C  42
ALA C 103
TYR C 116
ILE C  10
GLY C  31
None
None
CRQ  C  62 ( 4.7A)
None
None
1.24A 4l9qB-4tzaC:
undetectable
4l9qB-4tzaC:
18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M93_B_ACTB303_0
(S25-26 FAB (IGG1K)
HEAVY CHAIN
S25-26 FAB (IGG1K)
LIGHT CHAIN)
3ir8 LARGE STOKES SHIFT
FLUORESCENT PROTEIN

(Montipora
sp.
20)
4 / 5 GLY A  36
ALA A 213
PHE A  68
GLU A 211
None
None
None
CRQ  A  64 ( 3.3A)
1.00A 4m93B-3ir8A:
undetectable
4m93C-3ir8A:
undetectable
4m93B-3ir8A:
20.48
4m93C-3ir8A:
25.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M93_B_ACTB303_0
(S25-26 FAB (IGG1K)
HEAVY CHAIN
S25-26 FAB (IGG1K)
LIGHT CHAIN)
5y00 GREEN FLUORESCENT
PROTEIN

(Olindias)
4 / 5 GLY A  45
ALA A 225
PHE A  76
GLU A 223
None
None
None
CRQ  A  70 ( 2.7A)
1.04A 4m93B-5y00A:
undetectable
4m93C-5y00A:
undetectable
4m93B-5y00A:
undetectable
4m93C-5y00A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OLF_A_HFGA802_0
(PROLINE--TRNA LIGASE)
2vad RED FLUORESCENT
PROTEIN

(Discosoma
sp.)
5 / 12 PHE A 124
VAL A 122
HIS A 163
THR A 140
GLY A 142
None
None
CRQ  A  66 ( 3.9A)
None
None
1.17A 4olfA-2vadA:
undetectable
4olfA-2vadA:
18.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QTU_D_SAMD301_1
(PUTATIVE
METHYLTRANSFERASE
BUD23)
3ir8 LARGE STOKES SHIFT
FLUORESCENT PROTEIN

(Montipora
sp.
20)
4 / 5 GLN A  60
LEU A  61
SER A  58
ASP A 192
None
CRQ  A  64 ( 4.7A)
None
None
1.30A 4qtuD-3ir8A:
undetectable
4qtuD-3ir8A:
21.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UDC_A_DEXA1778_2
(GLUCOCORTICOID
RECEPTOR)
2ib5 CHROMO PROTEIN
(Epiactis
japonica)
3 / 3 MET A  25
GLN A 106
TYR A 117
None
CRQ  A  65 ( 4.1A)
CRQ  A  65 ( 4.1A)
1.00A 4udcA-2ib5A:
undetectable
4udcA-2ib5A:
22.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UUU_A_SAMA1546_0
(CYSTATHIONINE
BETA-SYNTHASE)
2c9i GREEN FLUORESCENT
PROTEIN ASFP499

(Anemonia
sulcata)
5 / 11 LEU A  58
PHE A  62
GLN A 210
HIS A 211
VAL A 208
None
None
CRQ  A  63 ( 3.9A)
None
None
1.31A 4uuuA-2c9iA:
undetectable
4uuuB-2c9iA:
undetectable
4uuuA-2c9iA:
19.75
4uuuB-2c9iA:
19.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XLD_A_BRLA502_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)
2vad RED FLUORESCENT
PROTEIN

(Discosoma
sp.)
5 / 12 SER A  62
PHE A 177
MET A  97
HIS A 163
LEU A 199
None
None
None
CRQ  A  66 ( 3.9A)
CRQ  A  66 ( 4.0A)
1.36A 4xldA-2vadA:
undetectable
4xldA-2vadA:
21.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GS4_A_ESTA603_1
(ESTROGEN RECEPTOR)
4jc2 ASFP504
(Alcyonium)
5 / 12 GLU A 211
ARG A  66
MET A  14
GLY A  27
LEU A  42
CRQ  A  64 ( 3.8A)
CRQ  A  64 ( 4.3A)
None
None
None
1.18A 5gs4A-4jc2A:
undetectable
5gs4A-4jc2A:
23.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GS4_A_ESTA603_1
(ESTROGEN RECEPTOR)
4tza FLUORESCENT PROTEIN
(synthetic
construct)
5 / 12 GLU C 211
ARG C  66
MET C  14
GLY C  27
LEU C  42
CRQ  C  62 ( 3.5A)
CRQ  C  62 ( 4.2A)
None
None
None
1.16A 5gs4A-4tzaC:
undetectable
5gs4A-4tzaC:
21.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M5C_B_TA1B502_1
(TUBULIN BETA-2B
CHAIN)
3adf MONOMERIC AZAMI
GREEN

(Galaxea
fascicularis)
5 / 12 VAL A 157
ASP A 156
GLU A 144
LEU A 161
SER A 142
None
None
None
None
CRQ  A  64 ( 2.8A)
1.19A 5m5cB-3adfA:
undetectable
5m5cB-3adfA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M5C_E_TA1E502_1
(TUBULIN BETA-2B
CHAIN)
3adf MONOMERIC AZAMI
GREEN

(Galaxea
fascicularis)
5 / 10 VAL A 157
ASP A 156
GLU A 144
LEU A 161
SER A 142
None
None
None
None
CRQ  A  64 ( 2.8A)
1.21A 5m5cE-3adfA:
undetectable
5m5cE-3adfA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NUJ_A_Z80A201_1
(BETA-LACTOGLOBULIN)
3cgl GFP-LIKE FLUORESCENT
CHROMOPROTEIN
DSFP483

(Discosoma
striata)
4 / 8 VAL A  44
LEU A  46
ILE A 122
ASN A 109
CRQ  A  66 ( 4.3A)
None
None
CRQ  A  66 ( 4.1A)
0.82A 5nujA-3cglA:
undetectable
5nujA-3cglA:
13.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5U6M_A_SALA503_1
(UDP-GLYCOSYLTRANSFER
ASE 74F2)
2vad RED FLUORESCENT
PROTEIN

(Discosoma
sp.)
4 / 7 THR A 179
PHE A  91
GLN A 109
MET A  83
None
None
CRQ  A  66 ( 4.0A)
CL  A1227 (-4.6A)
1.43A 5u6mA-2vadA:
undetectable
5u6mA-2vadA:
18.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XIP_A_HFGA1003_0
(PROLYL-TRNA
SYNTHETASE, PUTATIVE)
2vad RED FLUORESCENT
PROTEIN

(Discosoma
sp.)
6 / 12 PHE A 124
VAL A 122
HIS A 163
PHE A  99
THR A 140
GLY A 142
None
None
CRQ  A  66 ( 3.9A)
None
None
None
1.24A 5xipA-2vadA:
undetectable
5xipA-2vadA:
17.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XIP_B_HFGB1003_0
(PROLYL-TRNA
SYNTHETASE, PUTATIVE)
2vad RED FLUORESCENT
PROTEIN

(Discosoma
sp.)
5 / 12 PHE A 124
VAL A 122
HIS A 163
PHE A  99
THR A 140
None
None
CRQ  A  66 ( 3.9A)
None
None
1.33A 5xipB-2vadA:
undetectable
5xipB-2vadA:
17.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XIP_C_HFGC1003_0
(PROLYL-TRNA
SYNTHETASE, PUTATIVE)
2vad RED FLUORESCENT
PROTEIN

(Discosoma
sp.)
5 / 12 VAL A 122
HIS A 163
PHE A  99
THR A 140
GLY A 142
None
CRQ  A  66 ( 3.9A)
None
None
None
1.21A 5xipC-2vadA:
undetectable
5xipC-2vadA:
17.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XIQ_D_HFGD1002_0
(PROLYL-TRNA
SYNTHETASE (PRORS))
2vad RED FLUORESCENT
PROTEIN

(Discosoma
sp.)
5 / 12 PHE A 124
VAL A 122
HIS A 163
THR A 140
GLY A 142
None
None
CRQ  A  66 ( 3.9A)
None
None
1.15A 5xiqD-2vadA:
undetectable
5xiqD-2vadA:
19.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MB7_A_PARA900_0
(AAC(3)-IIIB PROTEIN)
3adf MONOMERIC AZAMI
GREEN

(Galaxea
fascicularis)
5 / 10 ASN A  32
TYR A 116
THR A  37
GLY A  29
ASP A  41
None
CRQ  A  64 ( 4.6A)
None
None
None
1.21A 6mb7A-3adfA:
0.0
6mb7A-3adfA:
13.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NKN_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)
3adf MONOMERIC AZAMI
GREEN

(Galaxea
fascicularis)
3 / 3 ARG A  66
PHE A  61
PHE A  68
CRQ  A  64 ( 3.8A)
None
None
1.08A 6nknC-3adfA:
undetectable
6nknJ-3adfA:
undetectable
6nknC-3adfA:
17.47
6nknJ-3adfA:
14.04