SIMILAR PATTERN OF AMINO ACIDS MAPPED TO 'CRO'


List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A29_A_TFPA154_1
(CALMODULIN)		 2h5r MSTRAWBERRY
(Discosoma
sp.) 		5 / 10 ALA A  44
LEU A 213
LEU A  61
GLU A  28
MET A  18
 None
CRO  A  66 ( 4.3A)
None
None
None
 1.31A 1a29A-2h5rA:
undetectable		 1a29A-2h5rA:
22.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DTL_A_BEPA205_1
(CARDIAC TROPONIN C)		 2rh7 GREEN FLUORESCENT
PROTEIN
(Renilla
reniformis) 		5 / 12 ALA A  64
PHE A 124
MET A  29
PHE A 165
LEU A 200
 None
None
None
None
CRO  A  66 ( 4.2A)
 1.19A 1dtlA-2rh7A:
undetectable		 1dtlA-2rh7A:
22.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ETB_2_T442129_1
(TRANSTHYRETIN)		 4xbi CLPB PROTEIN,
PUTATIVE,GREEN
FLUORESCENT PROTEIN
(Aequorea
victoria;
Plasmodium
falciparum) 		4 / 6 LEU A 193
GLU A 181
THR A 267
LEU A 191
 CRO  A 215 ( 4.8A)
None
None
CRO  A 215 ( 4.9A)
 1.15A 1etb2-4xbiA:
undetectable		 1etb2-4xbiA:
15.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ETB_2_T442129_1
(TRANSTHYRETIN)		 4xgy GREEN FLUORESCENT
PROTEIN, MAB LCDR3,
GREEN FLUORESCENT
PROTEIN
(Aequorea
victoria;
Vibrio
parahaemolyticus
;
synthetic
construct) 		4 / 6 LEU A  44
GLU A  32
THR A 118
LEU A  42
 CRO  A  66 ( 4.4A)
None
None
CRO  A  66 ( 4.7A)
 1.19A 1etb2-4xgyA:
0.7		 1etb2-4xgyA:
17.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ETB_2_T442129_1
(TRANSTHYRETIN)		 5mse GREEN FLUORESCENT
PROTEIN
(Aequorea
victoria) 		4 / 6 LEU A  44
GLU A  32
THR A 118
LEU A  42
 CRO  A  66 ( 4.8A)
None
None
None
 1.24A 1etb2-5mseA:
undetectable		 1etb2-5mseA:
19.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RJ6_A_AZMA400_1
(CARBONIC ANHYDRASE
XIV)		 2b3q GREEN FLUORESCENT
PROTEIN
(Aequorea
victoria) 		5 / 10 HIS A 181
LEU A  53
LEU A  64
THR A  62
THR A  63
 None
None
CRO  A  66 ( 4.1A)
CRO  A  66 ( 4.5A)
None
 1.42A 1rj6A-2b3qA:
undetectable		 1rj6A-2b3qA:
21.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RJ6_A_AZMA400_1
(CARBONIC ANHYDRASE
XIV)		 3evp GREEN FLUORESCENT
PROTEIN,GREEN
FLUORESCENT PROTEIN
(Aequorea
victoria) 		5 / 10 HIS A  94
LEU A 211
LEU A 222
THR A 220
THR A 221
 None
None
CRO  A 224 ( 4.2A)
CRO  A 224 ( 4.5A)
None
 1.39A 1rj6A-3evpA:
undetectable		 1rj6A-3evpA:
21.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RJ6_A_AZMA400_1
(CARBONIC ANHYDRASE
XIV)		 3evr MYOSIN LIGHT CHAIN
KINASE, GREEN
FLUORESCENT PROTEIN,
CALMODULIN-1 CHIMERA
(Aequorea
victoria;
Rattus
norvegicus) 		5 / 10 HIS A  94
LEU A 211
LEU A 222
THR A 220
THR A 221
 None
None
CRO  A 224 ( 4.2A)
CRO  A 224 ( 4.6A)
None
 1.41A 1rj6A-3evrA:
undetectable		 1rj6A-3evrA:
18.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RJ6_A_AZMA400_1
(CARBONIC ANHYDRASE
XIV)		 4pfe GREEN FLUORESCENT
PROTEIN
(Aequorea
victoria;
Vicugna
pacos) 		5 / 10 HIS A 181
LEU A  53
LEU A  64
THR A  62
THR A  63
 None
None
CRO  A  66 ( 3.9A)
CRO  A  66 ( 4.7A)
None
 1.37A 1rj6A-4pfeA:
undetectable		 1rj6A-4pfeA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RJ6_A_AZMA400_1
(CARBONIC ANHYDRASE
XIV)		 4xbi CLPB PROTEIN,
PUTATIVE,GREEN
FLUORESCENT PROTEIN
(Aequorea
victoria;
Plasmodium
falciparum) 		5 / 10 HIS A 330
LEU A 202
LEU A 213
THR A 211
THR A 212
 None
None
CRO  A 215 ( 4.2A)
CRO  A 215 ( 4.8A)
None
 1.39A 1rj6A-4xbiA:
undetectable		 1rj6A-4xbiA:
20.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RJ6_A_AZMA400_1
(CARBONIC ANHYDRASE
XIV)		 4xgy GREEN FLUORESCENT
PROTEIN, MAB LCDR3,
GREEN FLUORESCENT
PROTEIN
(Aequorea
victoria;
Vibrio
parahaemolyticus
;
synthetic
construct) 		5 / 10 HIS A 194
LEU A  53
LEU A  64
THR A  62
THR A  63
 None
None
CRO  A  66 ( 4.2A)
CRO  A  66 ( 4.6A)
None
 1.39A 1rj6A-4xgyA:
undetectable		 1rj6A-4xgyA:
21.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RJ6_B_AZMB401_1
(CARBONIC ANHYDRASE
XIV)		 2b3q GREEN FLUORESCENT
PROTEIN
(Aequorea
victoria) 		5 / 10 HIS A 181
LEU A  53
LEU A  64
THR A  62
THR A  63
 None
None
CRO  A  66 ( 4.1A)
CRO  A  66 ( 4.5A)
None
 1.38A 1rj6B-2b3qA:
undetectable		 1rj6B-2b3qA:
21.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RJ6_B_AZMB401_1
(CARBONIC ANHYDRASE
XIV)		 3evp GREEN FLUORESCENT
PROTEIN,GREEN
FLUORESCENT PROTEIN
(Aequorea
victoria) 		5 / 10 HIS A  94
LEU A 211
LEU A 222
THR A 220
THR A 221
 None
None
CRO  A 224 ( 4.2A)
CRO  A 224 ( 4.5A)
None
 1.38A 1rj6B-3evpA:
undetectable		 1rj6B-3evpA:
21.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RJ6_B_AZMB401_1
(CARBONIC ANHYDRASE
XIV)		 3evr MYOSIN LIGHT CHAIN
KINASE, GREEN
FLUORESCENT PROTEIN,
CALMODULIN-1 CHIMERA
(Aequorea
victoria;
Rattus
norvegicus) 		5 / 10 HIS A  94
LEU A 211
LEU A 222
THR A 220
THR A 221
 None
None
CRO  A 224 ( 4.2A)
CRO  A 224 ( 4.6A)
None
 1.39A 1rj6B-3evrA:
undetectable		 1rj6B-3evrA:
18.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RJ6_B_AZMB401_1
(CARBONIC ANHYDRASE
XIV)		 4pfe GREEN FLUORESCENT
PROTEIN
(Aequorea
victoria;
Vicugna
pacos) 		5 / 10 HIS A 181
LEU A  53
LEU A  64
THR A  62
THR A  63
 None
None
CRO  A  66 ( 3.9A)
CRO  A  66 ( 4.7A)
None
 1.36A 1rj6B-4pfeA:
undetectable		 1rj6B-4pfeA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RJ6_B_AZMB401_1
(CARBONIC ANHYDRASE
XIV)		 4xbi CLPB PROTEIN,
PUTATIVE,GREEN
FLUORESCENT PROTEIN
(Aequorea
victoria;
Plasmodium
falciparum) 		5 / 10 HIS A 330
LEU A 202
LEU A 213
THR A 211
THR A 212
 None
None
CRO  A 215 ( 4.2A)
CRO  A 215 ( 4.8A)
None
 1.37A 1rj6B-4xbiA:
undetectable		 1rj6B-4xbiA:
20.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RJ6_B_AZMB401_1
(CARBONIC ANHYDRASE
XIV)		 4xgy GREEN FLUORESCENT
PROTEIN, MAB LCDR3,
GREEN FLUORESCENT
PROTEIN
(Aequorea
victoria;
Vibrio
parahaemolyticus
;
synthetic
construct) 		5 / 10 HIS A 194
LEU A  53
LEU A  64
THR A  62
THR A  63
 None
None
CRO  A  66 ( 4.2A)
CRO  A  66 ( 4.6A)
None
 1.37A 1rj6B-4xgyA:
undetectable		 1rj6B-4xgyA:
21.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XDK_B_9CRB600_2
(RETINOIC ACID
RECEPTOR, BETA)		 2h5r MSTRAWBERRY
(Discosoma
sp.) 		3 / 3 LEU A  54
PHE A  27
ARG A  95
 None
None
CRO  A  66 ( 2.9A)
 0.80A 1xdkB-2h5rA:
undetectable		 1xdkB-2h5rA:
20.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A69_C_RPTC8001_1
(DNA-DIRECTED RNA
POLYMERASE BETA
CHAIN
RNA POLYMERASE SIGMA
FACTOR RPOD)		 4he4 YELLOW FLUORESCENT
PROTEIN
(Phialidium
sp.
SL-2003) 		5 / 11 GLN A  69
PHE A  71
SER A 161
PRO A 196
ILE A 150
 CRO  A  65 ( 4.2A)
None
None
None
None
 1.46A 2a69C-4he4A:
0.0
2a69F-4he4A:
undetectable		 2a69C-4he4A:
11.88
2a69F-4he4A:
18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NNI_A_MTKA501_1
(CYTOCHROME P450 2C8)		 3evr MYOSIN LIGHT CHAIN
KINASE, GREEN
FLUORESCENT PROTEIN,
CALMODULIN-1 CHIMERA
(Aequorea
victoria;
Rattus
norvegicus) 		5 / 12 SER A 230
THR A 116
THR A 303
VAL A 219
VAL A 174
 None
CRO  A 224 ( 3.1A)
None
CRO  A 224 ( 4.6A)
None
 1.28A 2nniA-3evrA:
undetectable		 2nniA-3evrA:
21.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QB4_A_DSMA801_1
(TRANSPORTER)		 3evr MYOSIN LIGHT CHAIN
KINASE, GREEN
FLUORESCENT PROTEIN,
CALMODULIN-1 CHIMERA
(Aequorea
victoria;
Rattus
norvegicus) 		5 / 12 LEU A 202
LEU A 200
ILE A 172
ALA A 195
PHE A 229
 CRO  A 224 ( 4.7A)
None
None
None
None
 1.16A 2qb4A-3evrA:
undetectable		 2qb4A-3evrA:
21.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QB4_A_DSMA801_1
(TRANSPORTER)		 4pfe GREEN FLUORESCENT
PROTEIN
(Aequorea
victoria;
Vicugna
pacos) 		5 / 12 LEU A  44
LEU A  42
ILE A  14
ALA A  37
PHE A  71
 None
CRO  A  66 ( 4.8A)
None
None
None
 1.17A 2qb4A-4pfeA:
undetectable		 2qb4A-4pfeA:
21.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QB4_A_DSMA801_1
(TRANSPORTER)		 4xbi CLPB PROTEIN,
PUTATIVE,GREEN
FLUORESCENT PROTEIN
(Aequorea
victoria;
Plasmodium
falciparum) 		5 / 12 LEU A 193
LEU A 191
ILE A 163
ALA A 186
PHE A 220
 CRO  A 215 ( 4.8A)
CRO  A 215 ( 4.9A)
None
None
None
 1.17A 2qb4A-4xbiA:
undetectable		 2qb4A-4xbiA:
21.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QB4_A_DSMA801_1
(TRANSPORTER)		 5mse GREEN FLUORESCENT
PROTEIN
(Aequorea
victoria) 		5 / 12 LEU A  44
LEU A  42
ILE A  14
ALA A  37
PHE A  71
 CRO  A  66 ( 4.8A)
None
None
None
None
 1.17A 2qb4A-5mseA:
undetectable		 2qb4A-5mseA:
10.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QBN_A_CAMA442_0
(CYTOCHROME P450-CAM)		 2rh7 GREEN FLUORESCENT
PROTEIN
(Renilla
reniformis) 		4 / 7 TYR A 181
THR A 179
VAL A  63
VAL A 122
 None
None
CRO  A  66 ( 3.9A)
None
 0.97A 2qbnA-2rh7A:
undetectable		 2qbnA-2rh7A:
20.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZBU_D_ADND504_1
(UNCHARACTERIZED
CONSERVED PROTEIN)		 2rh7 GREEN FLUORESCENT
PROTEIN
(Renilla
reniformis) 		3 / 3 PHE A 118
ASN A  69
PHE A  91
 None
CRO  A  66 ( 4.8A)
None
 0.87A 2zbuD-2rh7A:
undetectable		 2zbuD-2rh7A:
24.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_B_SVRB512_1
(PHOSPHOLIPASE A2)		 5mse GREEN FLUORESCENT
PROTEIN
(Aequorea
victoria) 		4 / 5 VAL A 112
VAL A 111
THR A  63
ARG A 113
 CRO  A  66 ( 4.9A)
None
None
None
 1.17A 3bjwA-5mseA:
undetectable		 3bjwA-5mseA:
17.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IK6_H_HCZH800_1
(GLUTAMATE RECEPTOR 2)		 4xgy GREEN FLUORESCENT
PROTEIN, MAB LCDR3,
GREEN FLUORESCENT
PROTEIN
(Aequorea
victoria;
Vibrio
parahaemolyticus
;
synthetic
construct) 		4 / 4 LYS A  41
SER A 215
LEU A 234
SER A 218
 PE5  A 301 (-2.5A)
None
PE5  A 301 (-4.1A)
CRO  A  66 ( 3.2A)
 1.45A 3ik6H-4xgyA:
0.0		 3ik6H-4xgyA:
21.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ILU_H_HFZH800_1
(GLUTAMATE RECEPTOR 2)		 4xgy GREEN FLUORESCENT
PROTEIN, MAB LCDR3,
GREEN FLUORESCENT
PROTEIN
(Aequorea
victoria;
Vibrio
parahaemolyticus
;
synthetic
construct) 		4 / 5 LYS A  41
SER A 215
LEU A 234
SER A 218
 PE5  A 301 (-2.5A)
None
PE5  A 301 (-4.1A)
CRO  A  66 ( 3.2A)
 1.48A 3iluH-4xgyA:
undetectable		 3iluH-4xgyA:
21.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K4V_B_ROCB201_4
(HIV-1 PROTEASE)		 3evr MYOSIN LIGHT CHAIN
KINASE, GREEN
FLUORESCENT PROTEIN,
CALMODULIN-1 CHIMERA
(Aequorea
victoria;
Rattus
norvegicus) 		4 / 4 ARG A 377
ASP A 367
GLY A 362
THR A 138
 CRO  A 224 ( 4.9A)
CA  A   1 (-3.5A)
None
None
 1.30A 3k4vB-3evrA:
undetectable		 3k4vB-3evrA:
13.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SMT_A_ACTA500_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SETD3)		 4p7h MYOSIN-7,GREEN
FLUORESCENT PROTEIN
(Aequorea
victoria;
Homo
sapiens) 		3 / 3 PHE A 871
SER A 859
GLN A 856
 None
None
CRO  A 853 ( 2.9A)
 0.87A 3smtA-4p7hA:
undetectable		 3smtA-4p7hA:
18.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SNF_A_ACTA110_0
(PROTEIN P-30)		 4he4 YELLOW FLUORESCENT
PROTEIN
(Phialidium
sp.
SL-2003) 		4 / 5 ILE A 165
THR A  59
SER A  58
PHE A 143
 None
None
None
CRO  A  65 ( 4.7A)
 0.97A 3snfA-4he4A:
undetectable		 3snfA-4he4A:
19.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3R_B_9PLB501_1
(CYTOCHROME P450 2A6)		 2b3q GREEN FLUORESCENT
PROTEIN
(Aequorea
victoria) 		5 / 9 PHE A  71
VAL A 112
ASN A 121
ILE A  14
PHE A   8
 None
None
CRO  A  66 ( 3.4A)
None
None
 1.16A 3t3rB-2b3qA:
undetectable		 3t3rB-2b3qA:
19.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3R_B_9PLB501_1
(CYTOCHROME P450 2A6)		 3ed8 YELLOW FLUORESCENCE
PROTEIN
(Aequorea
victoria) 		5 / 9 PHE A  71
VAL A 112
ASN A 121
ILE A  14
PHE A   8
 None
None
CRO  A  66 ( 3.9A)
None
None
 1.16A 3t3rB-3ed8A:
undetectable		 3t3rB-3ed8A:
18.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3R_B_9PLB501_1
(CYTOCHROME P450 2A6)		 3evp GREEN FLUORESCENT
PROTEIN,GREEN
FLUORESCENT PROTEIN
(Aequorea
victoria) 		5 / 9 PHE A 229
VAL A 270
ASN A 279
ILE A 172
PHE A 166
 None
CRO  A 224 ( 4.9A)
CRO  A 224 ( 3.6A)
None
None
 1.21A 3t3rB-3evpA:
undetectable		 3t3rB-3evpA:
18.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3R_B_9PLB501_1
(CYTOCHROME P450 2A6)		 3evr MYOSIN LIGHT CHAIN
KINASE, GREEN
FLUORESCENT PROTEIN,
CALMODULIN-1 CHIMERA
(Aequorea
victoria;
Rattus
norvegicus) 		5 / 9 PHE A 229
VAL A 270
ASN A 279
ILE A 172
PHE A 166
 None
CRO  A 224 ( 4.8A)
CRO  A 224 ( 3.6A)
None
None
 1.20A 3t3rB-3evrA:
undetectable		 3t3rB-3evrA:
23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3R_B_9PLB501_1
(CYTOCHROME P450 2A6)		 3u8p CYTOCHROME B562
INTEGRAL FUSION WITH
ENHANCED GREEN
FLUORESCENT PROTEIN
(Aequorea
victoria;
Escherichia
coli) 		5 / 9 PHE A 179
VAL A 220
ASN A 229
ILE A  14
PHE A   8
 None
CRO  A 175 ( 4.8A)
CRO  A 175 ( 3.5A)
None
None
 1.19A 3t3rB-3u8pA:
undetectable		 3t3rB-3u8pA:
20.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3R_B_9PLB501_1
(CYTOCHROME P450 2A6)		 4kf5 FLUORESCENT PROTEIN
GFP1-9
(synthetic
construct) 		5 / 9 PHE A  71
VAL A 112
ASN A 121
ILE A  14
PHE A   8
 None
CRO  A  66 ( 4.9A)
CRO  A  66 ( 4.1A)
None
None
 1.21A 3t3rB-4kf5A:
undetectable		 3t3rB-4kf5A:
19.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3R_B_9PLB501_1
(CYTOCHROME P450 2A6)		 4p7h MYOSIN-7,GREEN
FLUORESCENT PROTEIN
(Aequorea
victoria;
Homo
sapiens) 		5 / 9 PHE A 858
VAL A 899
ASN A 908
ILE A 801
PHE A 795
 None
None
CRO  A 853 ( 4.3A)
None
None
 1.17A 3t3rB-4p7hA:
undetectable		 3t3rB-4p7hA:
18.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3R_B_9PLB501_1
(CYTOCHROME P450 2A6)		 4pfe GREEN FLUORESCENT
PROTEIN
(Aequorea
victoria;
Vicugna
pacos) 		5 / 9 PHE A  71
VAL A 112
ASN A 121
ILE A  14
PHE A   8
 None
CRO  A  66 ( 4.9A)
CRO  A  66 ( 4.0A)
None
None
 1.23A 3t3rB-4pfeA:
undetectable		 3t3rB-4pfeA:
22.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3R_B_9PLB501_1
(CYTOCHROME P450 2A6)		 4xbi CLPB PROTEIN,
PUTATIVE,GREEN
FLUORESCENT PROTEIN
(Aequorea
victoria;
Plasmodium
falciparum) 		5 / 9 PHE A 220
VAL A 261
ASN A 270
ILE A 163
PHE A 157
 None
CRO  A 215 ( 4.9A)
CRO  A 215 ( 3.6A)
None
None
 1.20A 3t3rB-4xbiA:
undetectable		 3t3rB-4xbiA:
22.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3R_B_9PLB501_1
(CYTOCHROME P450 2A6)		 4xgy GREEN FLUORESCENT
PROTEIN, MAB LCDR3,
GREEN FLUORESCENT
PROTEIN
(Aequorea
victoria;
Vibrio
parahaemolyticus
;
synthetic
construct) 		5 / 9 PHE A  71
VAL A 112
ASN A 121
ILE A  14
PHE A   8
 None
CRO  A  66 ( 4.8A)
CRO  A  66 ( 3.6A)
None
None
 1.19A 3t3rB-4xgyA:
undetectable		 3t3rB-4xgyA:
19.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3R_B_9PLB501_1
(CYTOCHROME P450 2A6)		 5mse GREEN FLUORESCENT
PROTEIN
(Aequorea
victoria) 		5 / 9 PHE A  71
VAL A 112
ASN A 121
ILE A  14
PHE A   8
 None
CRO  A  66 ( 4.9A)
CRO  A  66 ( 3.7A)
None
None
 1.18A 3t3rB-5mseA:
undetectable		 3t3rB-5mseA:
11.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3R_C_9PLC501_1
(CYTOCHROME P450 2A6)		 2b3q GREEN FLUORESCENT
PROTEIN
(Aequorea
victoria) 		5 / 9 PHE A  71
VAL A 112
ASN A 121
ILE A  14
PHE A   8
 None
None
CRO  A  66 ( 3.4A)
None
None
 1.20A 3t3rC-2b3qA:
undetectable		 3t3rC-2b3qA:
19.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3R_C_9PLC501_1
(CYTOCHROME P450 2A6)		 3ed8 YELLOW FLUORESCENCE
PROTEIN
(Aequorea
victoria) 		5 / 9 PHE A  71
VAL A 112
ASN A 121
ILE A  14
PHE A   8
 None
None
CRO  A  66 ( 3.9A)
None
None
 1.18A 3t3rC-3ed8A:
undetectable		 3t3rC-3ed8A:
18.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3R_C_9PLC501_1
(CYTOCHROME P450 2A6)		 3evp GREEN FLUORESCENT
PROTEIN,GREEN
FLUORESCENT PROTEIN
(Aequorea
victoria) 		5 / 9 PHE A 229
VAL A 270
ASN A 279
ILE A 172
PHE A 166
 None
CRO  A 224 ( 4.9A)
CRO  A 224 ( 3.6A)
None
None
 1.25A 3t3rC-3evpA:
undetectable		 3t3rC-3evpA:
18.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3R_C_9PLC501_1
(CYTOCHROME P450 2A6)		 3evr MYOSIN LIGHT CHAIN
KINASE, GREEN
FLUORESCENT PROTEIN,
CALMODULIN-1 CHIMERA
(Aequorea
victoria;
Rattus
norvegicus) 		5 / 9 PHE A 229
VAL A 270
ASN A 279
ILE A 172
PHE A 166
 None
CRO  A 224 ( 4.8A)
CRO  A 224 ( 3.6A)
None
None
 1.23A 3t3rC-3evrA:
undetectable		 3t3rC-3evrA:
23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3R_C_9PLC501_1
(CYTOCHROME P450 2A6)		 3u8p CYTOCHROME B562
INTEGRAL FUSION WITH
ENHANCED GREEN
FLUORESCENT PROTEIN
(Aequorea
victoria;
Escherichia
coli) 		5 / 9 PHE A 179
VAL A 220
ASN A 229
ILE A  14
PHE A   8
 None
CRO  A 175 ( 4.8A)
CRO  A 175 ( 3.5A)
None
None
 1.23A 3t3rC-3u8pA:
undetectable		 3t3rC-3u8pA:
20.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3R_C_9PLC501_1
(CYTOCHROME P450 2A6)		 4kf5 FLUORESCENT PROTEIN
GFP1-9
(synthetic
construct) 		5 / 9 PHE A  71
VAL A 112
ASN A 121
ILE A  14
PHE A   8
 None
CRO  A  66 ( 4.9A)
CRO  A  66 ( 4.1A)
None
None
 1.25A 3t3rC-4kf5A:
undetectable		 3t3rC-4kf5A:
19.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3R_C_9PLC501_1
(CYTOCHROME P450 2A6)		 4p7h MYOSIN-7,GREEN
FLUORESCENT PROTEIN
(Aequorea
victoria;
Homo
sapiens) 		5 / 9 PHE A 858
VAL A 899
ASN A 908
ILE A 801
PHE A 795
 None
None
CRO  A 853 ( 4.3A)
None
None
 1.23A 3t3rC-4p7hA:
undetectable		 3t3rC-4p7hA:
18.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3R_C_9PLC501_1
(CYTOCHROME P450 2A6)		 4pfe GREEN FLUORESCENT
PROTEIN
(Aequorea
victoria;
Vicugna
pacos) 		5 / 9 PHE A  71
VAL A 112
ASN A 121
ILE A  14
PHE A   8
 None
CRO  A  66 ( 4.9A)
CRO  A  66 ( 4.0A)
None
None
 1.27A 3t3rC-4pfeA:
undetectable		 3t3rC-4pfeA:
22.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3R_C_9PLC501_1
(CYTOCHROME P450 2A6)		 4xbi CLPB PROTEIN,
PUTATIVE,GREEN
FLUORESCENT PROTEIN
(Aequorea
victoria;
Plasmodium
falciparum) 		5 / 9 PHE A 220
VAL A 261
ASN A 270
ILE A 163
PHE A 157
 None
CRO  A 215 ( 4.9A)
CRO  A 215 ( 3.6A)
None
None
 1.24A 3t3rC-4xbiA:
undetectable		 3t3rC-4xbiA:
22.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3R_C_9PLC501_1
(CYTOCHROME P450 2A6)		 4xgy GREEN FLUORESCENT
PROTEIN, MAB LCDR3,
GREEN FLUORESCENT
PROTEIN
(Aequorea
victoria;
Vibrio
parahaemolyticus
;
synthetic
construct) 		5 / 9 PHE A  71
VAL A 112
ASN A 121
ILE A  14
PHE A   8
 None
CRO  A  66 ( 4.8A)
CRO  A  66 ( 3.6A)
None
None
 1.22A 3t3rC-4xgyA:
undetectable		 3t3rC-4xgyA:
19.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3R_C_9PLC501_1
(CYTOCHROME P450 2A6)		 5mse GREEN FLUORESCENT
PROTEIN
(Aequorea
victoria) 		5 / 9 PHE A  71
VAL A 112
ASN A 121
ILE A  14
PHE A   8
 None
CRO  A  66 ( 4.9A)
CRO  A  66 ( 3.7A)
None
None
 1.21A 3t3rC-5mseA:
undetectable		 3t3rC-5mseA:
11.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3R_D_9PLD501_1
(CYTOCHROME P450 2A6)		 2b3q GREEN FLUORESCENT
PROTEIN
(Aequorea
victoria) 		5 / 10 PHE A  71
VAL A 112
ASN A 121
ILE A  14
PHE A   8
 None
None
CRO  A  66 ( 3.4A)
None
None
 1.15A 3t3rD-2b3qA:
undetectable		 3t3rD-2b3qA:
19.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3R_D_9PLD501_1
(CYTOCHROME P450 2A6)		 3ed8 YELLOW FLUORESCENCE
PROTEIN
(Aequorea
victoria) 		5 / 10 PHE A  71
VAL A 112
ASN A 121
ILE A  14
PHE A   8
 None
None
CRO  A  66 ( 3.9A)
None
None
 1.13A 3t3rD-3ed8A:
undetectable		 3t3rD-3ed8A:
18.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3R_D_9PLD501_1
(CYTOCHROME P450 2A6)		 3evp GREEN FLUORESCENT
PROTEIN,GREEN
FLUORESCENT PROTEIN
(Aequorea
victoria) 		5 / 10 PHE A 229
VAL A 270
ASN A 279
ILE A 172
PHE A 166
 None
CRO  A 224 ( 4.9A)
CRO  A 224 ( 3.6A)
None
None
 1.19A 3t3rD-3evpA:
undetectable		 3t3rD-3evpA:
18.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3R_D_9PLD501_1
(CYTOCHROME P450 2A6)		 3evr MYOSIN LIGHT CHAIN
KINASE, GREEN
FLUORESCENT PROTEIN,
CALMODULIN-1 CHIMERA
(Aequorea
victoria;
Rattus
norvegicus) 		5 / 10 PHE A 229
VAL A 270
ASN A 279
ILE A 172
PHE A 166
 None
CRO  A 224 ( 4.8A)
CRO  A 224 ( 3.6A)
None
None
 1.19A 3t3rD-3evrA:
undetectable		 3t3rD-3evrA:
23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3R_D_9PLD501_1
(CYTOCHROME P450 2A6)		 3u8p CYTOCHROME B562
INTEGRAL FUSION WITH
ENHANCED GREEN
FLUORESCENT PROTEIN
(Aequorea
victoria;
Escherichia
coli) 		5 / 10 PHE A 179
VAL A 220
ASN A 229
ILE A  14
PHE A   8
 None
CRO  A 175 ( 4.8A)
CRO  A 175 ( 3.5A)
None
None
 1.19A 3t3rD-3u8pA:
undetectable		 3t3rD-3u8pA:
20.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3R_D_9PLD501_1
(CYTOCHROME P450 2A6)		 4kf5 FLUORESCENT PROTEIN
GFP1-9
(synthetic
construct) 		5 / 10 PHE A  71
VAL A 112
ASN A 121
ILE A  14
PHE A   8
 None
CRO  A  66 ( 4.9A)
CRO  A  66 ( 4.1A)
None
None
 1.19A 3t3rD-4kf5A:
undetectable		 3t3rD-4kf5A:
19.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3R_D_9PLD501_1
(CYTOCHROME P450 2A6)		 4p7h MYOSIN-7,GREEN
FLUORESCENT PROTEIN
(Aequorea
victoria;
Homo
sapiens) 		5 / 10 PHE A 858
VAL A 899
ASN A 908
ILE A 801
PHE A 795
 None
None
CRO  A 853 ( 4.3A)
None
None
 1.18A 3t3rD-4p7hA:
undetectable		 3t3rD-4p7hA:
18.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3R_D_9PLD501_1
(CYTOCHROME P450 2A6)		 4pfe GREEN FLUORESCENT
PROTEIN
(Aequorea
victoria;
Vicugna
pacos) 		5 / 10 PHE A  71
VAL A 112
ASN A 121
ILE A  14
PHE A   8
 None
CRO  A  66 ( 4.9A)
CRO  A  66 ( 4.0A)
None
None
 1.21A 3t3rD-4pfeA:
undetectable		 3t3rD-4pfeA:
22.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3R_D_9PLD501_1
(CYTOCHROME P450 2A6)		 4xbi CLPB PROTEIN,
PUTATIVE,GREEN
FLUORESCENT PROTEIN
(Aequorea
victoria;
Plasmodium
falciparum) 		5 / 10 PHE A 220
VAL A 261
ASN A 270
ILE A 163
PHE A 157
 None
CRO  A 215 ( 4.9A)
CRO  A 215 ( 3.6A)
None
None
 1.19A 3t3rD-4xbiA:
1.5		 3t3rD-4xbiA:
22.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3R_D_9PLD501_1
(CYTOCHROME P450 2A6)		 4xgy GREEN FLUORESCENT
PROTEIN, MAB LCDR3,
GREEN FLUORESCENT
PROTEIN
(Aequorea
victoria;
Vibrio
parahaemolyticus
;
synthetic
construct) 		5 / 10 PHE A  71
VAL A 112
ASN A 121
ILE A  14
PHE A   8
 None
CRO  A  66 ( 4.8A)
CRO  A  66 ( 3.6A)
None
None
 1.17A 3t3rD-4xgyA:
undetectable		 3t3rD-4xgyA:
19.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3R_D_9PLD501_1
(CYTOCHROME P450 2A6)		 5mse GREEN FLUORESCENT
PROTEIN
(Aequorea
victoria) 		5 / 10 PHE A  71
VAL A 112
ASN A 121
ILE A  14
PHE A   8
 None
CRO  A  66 ( 4.9A)
CRO  A  66 ( 3.7A)
None
None
 1.17A 3t3rD-5mseA:
undetectable		 3t3rD-5mseA:
11.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4I00_A_ZMRA509_2
(NEURAMINIDASE)		 4he4 YELLOW FLUORESCENT
PROTEIN
(Phialidium
sp.
SL-2003) 		4 / 5 LEU A 207
TRP A  57
ILE A  29
ASN A 119
 None
None
None
CRO  A  65 ( 4.0A)
 1.40A 4i00A-4he4A:
undetectable		 4i00A-4he4A:
22.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K0S_A_AZMA302_1
(CARBONIC ANHYDRASE 2)		 4pfe GREEN FLUORESCENT
PROTEIN
(Aequorea
victoria;
Vicugna
pacos) 		5 / 11 HIS A 181
LEU A  53
LEU A  64
THR A  62
THR A  63
 None
None
CRO  A  66 ( 3.9A)
CRO  A  66 ( 4.7A)
None
 1.28A 4k0sA-4pfeA:
undetectable		 4k0sA-4pfeA:
22.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MI4_A_SPMA201_1
(SPERMIDINE
N1-ACETYLTRANSFERASE)		 4he4 YELLOW FLUORESCENT
PROTEIN
(Phialidium
sp.
SL-2003) 		4 / 6 ASN A 119
GLU A 113
TYR A 118
GLU A  17
 CRO  A  65 ( 4.0A)
None
None
None
 1.34A 4mi4A-4he4A:
undetectable		 4mi4A-4he4A:
20.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MJ8_C_SPMC201_1
(SPERMIDINE
N1-ACETYLTRANSFERASE)		 4he4 YELLOW FLUORESCENT
PROTEIN
(Phialidium
sp.
SL-2003) 		4 / 7 ASN A 119
GLU A 113
TYR A 118
GLU A  17
 CRO  A  65 ( 4.0A)
None
None
None
 1.32A 4mj8C-4he4A:
undetectable		 4mj8C-4he4A:
20.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O1Z_A_MXMA807_2
(PROSTAGLANDIN G/H
SYNTHASE 1)		 3evp GREEN FLUORESCENT
PROTEIN,GREEN
FLUORESCENT PROTEIN
(Aequorea
victoria) 		4 / 6 VAL A 213
LEU A 211
LEU A 283
PHE A  78
 None
None
None
CRO  A 224 ( 4.4A)
 0.95A 4o1zA-3evpA:
undetectable		 4o1zA-3evpA:
18.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O1Z_A_MXMA807_2
(PROSTAGLANDIN G/H
SYNTHASE 1)		 3evr MYOSIN LIGHT CHAIN
KINASE, GREEN
FLUORESCENT PROTEIN,
CALMODULIN-1 CHIMERA
(Aequorea
victoria;
Rattus
norvegicus) 		4 / 6 VAL A 213
LEU A 211
LEU A 283
PHE A  78
 None
None
None
CRO  A 224 ( 4.5A)
 0.93A 4o1zA-3evrA:
undetectable		 4o1zA-3evrA:
21.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O1Z_A_MXMA807_2
(PROSTAGLANDIN G/H
SYNTHASE 1)		 4p7h MYOSIN-7,GREEN
FLUORESCENT PROTEIN
(Aequorea
victoria;
Homo
sapiens) 		4 / 6 VAL A 842
LEU A 840
LEU A 912
PHE A 952
 None
None
None
CRO  A 853 ( 4.6A)
 0.88A 4o1zA-4p7hA:
undetectable		 4o1zA-4p7hA:
19.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O1Z_A_MXMA807_2
(PROSTAGLANDIN G/H
SYNTHASE 1)		 4xbi CLPB PROTEIN,
PUTATIVE,GREEN
FLUORESCENT PROTEIN
(Aequorea
victoria;
Plasmodium
falciparum) 		4 / 6 VAL A 204
LEU A 202
LEU A 274
PHE A 314
 None
None
None
CRO  A 215 ( 4.9A)
 1.00A 4o1zA-4xbiA:
1.3		 4o1zA-4xbiA:
20.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O1Z_A_MXMA807_2
(PROSTAGLANDIN G/H
SYNTHASE 1)		 4xgy GREEN FLUORESCENT
PROTEIN, MAB LCDR3,
GREEN FLUORESCENT
PROTEIN
(Aequorea
victoria;
Vibrio
parahaemolyticus
;
synthetic
construct) 		4 / 6 VAL A  55
LEU A  53
LEU A 125
PHE A 165
 None
None
None
CRO  A  66 ( 4.0A)
 1.00A 4o1zA-4xgyA:
undetectable		 4o1zA-4xgyA:
20.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O1Z_A_MXMA807_2
(PROSTAGLANDIN G/H
SYNTHASE 1)		 5mse GREEN FLUORESCENT
PROTEIN
(Aequorea
victoria) 		4 / 6 VAL A  55
LEU A  53
LEU A 125
PHE A 165
 None
None
None
CRO  A  66 ( 4.4A)
 0.91A 4o1zA-5mseA:
undetectable		 4o1zA-5mseA:
9.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QI9_A_MTXA201_1
(DIHYDROFOLATE
REDUCTASE)		 3evp GREEN FLUORESCENT
PROTEIN,GREEN
FLUORESCENT PROTEIN
(Aequorea
victoria) 		6 / 12 ALA A 268
LEU A 222
ILE A 172
LEU A 200
TYR A 250
THR A 266
 None
CRO  A 224 ( 4.2A)
None
CRO  A 224 ( 4.9A)
None
None
 1.49A 4qi9A-3evpA:
undetectable		 4qi9A-3evpA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QI9_A_MTXA201_1
(DIHYDROFOLATE
REDUCTASE)		 4pfe GREEN FLUORESCENT
PROTEIN
(Aequorea
victoria;
Vicugna
pacos) 		6 / 12 ALA A 110
LEU A  64
ILE A  14
LEU A  42
TYR A  92
THR A 108
 None
CRO  A  66 ( 3.9A)
None
CRO  A  66 ( 4.8A)
None
None
 1.48A 4qi9A-4pfeA:
undetectable		 4qi9A-4pfeA:
17.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QLE_B_FOLB201_0
(DIHYDROFOLATE
REDUCTASE)		 5mse GREEN FLUORESCENT
PROTEIN
(Aequorea
victoria) 		6 / 11 ALA A 110
LEU A  64
ILE A  14
LEU A  42
TYR A  92
THR A 108
 None
CRO  A  66 ( 4.3A)
None
None
None
None
 1.43A 4qleB-5mseA:
undetectable		 4qleB-5mseA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QLG_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)		 5mse GREEN FLUORESCENT
PROTEIN
(Aequorea
victoria) 		6 / 12 ALA A 110
LEU A  64
ILE A  14
LEU A  42
TYR A  92
THR A 108
 None
CRO  A  66 ( 4.3A)
None
None
None
None
 1.40A 4qlgA-5mseA:
undetectable		 4qlgA-5mseA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QLG_B_FOLB201_0
(DIHYDROFOLATE
REDUCTASE)		 4xbi CLPB PROTEIN,
PUTATIVE,GREEN
FLUORESCENT PROTEIN
(Plasmodium
falciparum;
Aequorea
victoria) 		6 / 12 ALA A 259
LEU A 213
ILE A 163
LEU A 191
TYR A 241
THR A 257
 None
CRO  A 215 ( 4.2A)
None
CRO  A 215 ( 4.9A)
None
None
 1.45A 4qlgB-4xbiA:
undetectable		 4qlgB-4xbiA:
17.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QLG_B_FOLB201_0
(DIHYDROFOLATE
REDUCTASE)		 4xgy GREEN FLUORESCENT
PROTEIN, MAB LCDR3,
GREEN FLUORESCENT
PROTEIN
(Vibrio
parahaemolyticus
;
Aequorea
victoria;
synthetic
construct) 		6 / 12 ALA A 110
LEU A  64
ILE A  14
LEU A  42
TYR A  92
THR A 108
 None
CRO  A  66 ( 4.2A)
None
CRO  A  66 ( 4.7A)
None
None
 1.44A 4qlgB-4xgyA:
undetectable		 4qlgB-4xgyA:
16.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QLG_B_FOLB201_0
(DIHYDROFOLATE
REDUCTASE)		 5mse GREEN FLUORESCENT
PROTEIN
(Aequorea
victoria) 		6 / 12 ALA A 110
LEU A  64
ILE A  14
LEU A  42
TYR A  92
THR A 108
 None
CRO  A  66 ( 4.3A)
None
None
None
None
 1.39A 4qlgB-5mseA:
undetectable		 4qlgB-5mseA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R87_I_SPMI202_1
(SPERMIDINE
N1-ACETYLTRANSFERASE)		 4he4 YELLOW FLUORESCENT
PROTEIN
(Phialidium
sp.
SL-2003) 		4 / 7 ASN A 119
GLU A 113
TYR A 118
GLU A  17
 CRO  A  65 ( 4.0A)
None
None
None
 1.27A 4r87I-4he4A:
undetectable		 4r87I-4he4A:
20.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X5I_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)		 3evp GREEN FLUORESCENT
PROTEIN,GREEN
FLUORESCENT PROTEIN
(Aequorea
victoria) 		6 / 12 ALA A 268
LEU A 222
ILE A 172
LEU A 200
TYR A 250
THR A 266
 None
CRO  A 224 ( 4.2A)
None
CRO  A 224 ( 4.9A)
None
None
 1.43A 4x5iA-3evpA:
undetectable		 4x5iA-3evpA:
18.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X5I_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)		 4pfe GREEN FLUORESCENT
PROTEIN
(Aequorea
victoria;
Vicugna
pacos) 		6 / 12 ALA A 110
LEU A  64
ILE A  14
LEU A  42
TYR A  92
THR A 108
 None
CRO  A  66 ( 3.9A)
None
CRO  A  66 ( 4.8A)
None
None
 1.44A 4x5iA-4pfeA:
undetectable		 4x5iA-4pfeA:
17.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EAJ_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)		 5mse GREEN FLUORESCENT
PROTEIN
(Aequorea
victoria) 		6 / 12 ALA A 110
LEU A  64
ILE A  14
LEU A  42
TYR A  92
THR A 108
 None
CRO  A  66 ( 4.3A)
None
None
None
None
 1.45A 5eajA-5mseA:
undetectable		 5eajA-5mseA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LSU_B_SAMB1304_1
(HISTONE-LYSINE
N-METHYLTRANSFERASE
NSD2)		 4he4 YELLOW FLUORESCENT
PROTEIN
(Phialidium
sp.
SL-2003) 		3 / 3 ASN A 119
TYR A  14
CYH A  70
 CRO  A  65 ( 4.0A)
None
None
 0.77A 5lsuB-4he4A:
undetectable		 5lsuB-4he4A:
21.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NU7_A_RTLA201_0
(RETINOL-BINDING
PROTEIN 4)		 4he4 YELLOW FLUORESCENT
PROTEIN
(Phialidium
sp.
SL-2003) 		4 / 8 ALA A 179
VAL A 121
GLN A  92
HIS A 146
 None
None
CRO  A  65 ( 3.7A)
CRO  A  65 ( 3.8A)
 1.03A 5nu7A-4he4A:
undetectable		 5nu7A-4he4A:
21.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y2T_B_8LXB501_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 5mse GREEN FLUORESCENT
PROTEIN
(Aequorea
victoria) 		4 / 8 GLU A 176
HIS A 148
MET A 218
LEU A  42
 None
CRO  A  66 ( 3.8A)
None
None
 1.06A 5y2tB-5mseA:
undetectable		 5y2tB-5mseA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AV6_D_H4BD502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 3evr MYOSIN LIGHT CHAIN
KINASE, GREEN
FLUORESCENT PROTEIN,
CALMODULIN-1 CHIMERA
(Aequorea
victoria;
Rattus
norvegicus) 		4 / 7 PHE A  78
SER A 115
VAL A 137
ARG A 254
 CRO  A 224 ( 4.5A)
None
None
CRO  A 224 ( 3.0A)
 1.38A 6av6C-3evrA:
undetectable
6av6D-3evrA:
undetectable		 6av6C-3evrA:
11.75
6av6D-3evrA:
11.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BBS_A_BZ1A302_1
(CARBONIC ANHYDRASE 2)		 3ed8 YELLOW FLUORESCENCE
PROTEIN
(Aequorea
victoria) 		5 / 12 HIS A 148
ILE A 185
PHE A  84
THR A  63
THR A  62
 CRO  A  66 ( 3.9A)
None
None
None
CRO  A  66 ( 4.5A)
 1.16A 6bbsA-3ed8A:
undetectable		 6bbsA-3ed8A:
14.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BBS_A_BZ1A302_1
(CARBONIC ANHYDRASE 2)		 4kf5 FLUORESCENT PROTEIN
GFP1-9
(synthetic
construct) 		5 / 12 HIS A 148
ILE A 161
PHE A  84
THR A  63
THR A  62
 CRO  A  66 ( 4.2A)
None
None
None
CRO  A  66 ( 4.5A)
 1.19A 6bbsA-4kf5A:
undetectable		 6bbsA-4kf5A:
18.00