SIMILAR PATTERN OF AMINO ACIDS MAPPED TO 'CRB'


List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KXH_A_ACRA598_1
(ALPHA-AMYLASE)		 1dqs PROTEIN
(3-DEHYDROQUINATE
SYNTHASE)
(Aspergillus
nidulans) 		5 / 12 HIS A 275
ALA A 279
GLY A 160
ASN A 268
GLU A 260
 CRB  A 401 (-4.2A)
None
None
CRB  A 401 (-3.0A)
None
 1.11A 1kxhA-1dqsA:
undetectable		 1kxhA-1dqsA:
22.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V55_P_CHDP4525_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I
CYTOCHROME C OXIDASE
POLYPEPTIDE III)		 1xaj 3-DEHYDROQUINATE
SYNTHASE
(Staphylococcus
aureus) 		4 / 7 LEU A 204
HIS A 242
TYR A 180
HIS A 246
 None
CRB  A 500 ( 3.9A)
None
CRB  A 500 (-4.1A)
 1.15A 1v55C-1xajA:
0.0
1v55N-1xajA:
undetectable
1v55P-1xajA:
undetectable		 1v55C-1xajA:
22.31
1v55N-1xajA:
22.14
1v55P-1xajA:
22.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JIH_A_097A1001_1
(ADAMTS-1)		 1dqs PROTEIN
(3-DEHYDROQUINATE
SYNTHASE)
(Aspergillus
nidulans) 		5 / 9 LEU A 286
HIS A 287
GLU A 278
HIS A 275
HIS A 271
 None
ZN  A 402 (-3.3A)
NAD  A 400 ( 4.8A)
CRB  A 401 (-4.2A)
ZN  A 402 ( 3.1A)
 1.47A 2jihA-1dqsA:
undetectable		 2jihA-1dqsA:
22.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OZR_E_HAEE3003_1
(COLLAGENASE 3)		 1dqs PROTEIN
(3-DEHYDROQUINATE
SYNTHASE)
(Aspergillus
nidulans) 		4 / 4 HIS A 287
GLU A 278
HIS A 275
HIS A 271
 ZN  A 402 (-3.3A)
NAD  A 400 ( 4.8A)
CRB  A 401 (-4.2A)
ZN  A 402 ( 3.1A)
 1.32A 2ozrE-1dqsA:
undetectable		 2ozrE-1dqsA:
18.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VQY_A_PARA1201_1
(AAC(6')-IB)		 1dqs PROTEIN
(3-DEHYDROQUINATE
SYNTHASE)
(Aspergillus
nidulans) 		5 / 12 GLY A 114
GLU A 278
VAL A 291
ASP A 146
ASP A 119
 NAD  A 400 (-3.0A)
NAD  A 400 ( 4.8A)
None
CRB  A 401 ( 2.9A)
NAD  A 400 (-3.1A)
 1.17A 2vqyA-1dqsA:
undetectable		 2vqyA-1dqsA:
19.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VQY_A_PARA1201_1
(AAC(6')-IB)		 1xaj 3-DEHYDROQUINATE
SYNTHASE
(Staphylococcus
aureus) 		5 / 12 GLY A  99
GLU A 249
VAL A 260
ASP A 130
ASP A 104
 NAD  A 400 (-3.5A)
NAD  A 400 ( 4.8A)
None
CRB  A 500 ( 3.2A)
NAD  A 400 (-2.9A)
 1.25A 2vqyA-1xajA:
undetectable		 2vqyA-1xajA:
21.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WKO_F_CUF154_0
(SUPEROXIDE DISMUTASE
[CU-ZN])		 1dqs PROTEIN
(3-DEHYDROQUINATE
SYNTHASE)
(Aspergillus
nidulans) 		4 / 5 HIS A 275
HIS A 271
VAL A 291
HIS A 287
 CRB  A 401 (-4.2A)
ZN  A 402 ( 3.1A)
None
ZN  A 402 (-3.3A)
 0.98A 2wkoF-1dqsA:
undetectable		 2wkoF-1dqsA:
17.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WKO_F_CUF154_0
(SUPEROXIDE DISMUTASE
[CU-ZN])		 1xaj 3-DEHYDROQUINATE
SYNTHASE
(Staphylococcus
aureus) 		4 / 5 HIS A 246
HIS A 242
VAL A 260
HIS A 256
 CRB  A 500 (-4.1A)
CRB  A 500 ( 3.9A)
None
ZN  A 600 ( 3.5A)
 1.06A 2wkoF-1xajA:
undetectable		 2wkoF-1xajA:
23.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y69_N_CHDN1517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1xaj 3-DEHYDROQUINATE
SYNTHASE
(Staphylococcus
aureus) 		4 / 8 LEU A 204
HIS A 242
TYR A 180
HIS A 246
 None
CRB  A 500 ( 3.9A)
None
CRB  A 500 (-4.1A)
 1.06A 2y69C-1xajA:
undetectable
2y69N-1xajA:
undetectable
2y69P-1xajA:
undetectable		 2y69C-1xajA:
22.31
2y69N-1xajA:
22.14
2y69P-1xajA:
22.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABL_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1xaj 3-DEHYDROQUINATE
SYNTHASE
(Staphylococcus
aureus) 		4 / 8 HIS A 242
TYR A 180
HIS A 246
LEU A 204
 CRB  A 500 ( 3.9A)
None
CRB  A 500 (-4.1A)
None
 1.11A 3ablA-1xajA:
undetectable
3ablC-1xajA:
undetectable
3ablP-1xajA:
undetectable		 3ablA-1xajA:
22.14
3ablC-1xajA:
22.31
3ablP-1xajA:
22.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABL_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1xaj 3-DEHYDROQUINATE
SYNTHASE
(Staphylococcus
aureus) 		4 / 8 LEU A 204
HIS A 242
TYR A 180
HIS A 246
 None
CRB  A 500 ( 3.9A)
None
CRB  A 500 (-4.1A)
 1.09A 3ablC-1xajA:
undetectable
3ablN-1xajA:
undetectable
3ablP-1xajA:
undetectable		 3ablC-1xajA:
22.31
3ablN-1xajA:
22.14
3ablP-1xajA:
22.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABM_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1xaj 3-DEHYDROQUINATE
SYNTHASE
(Staphylococcus
aureus) 		4 / 8 HIS A 242
TYR A 180
HIS A 246
LEU A 204
 CRB  A 500 ( 3.9A)
None
CRB  A 500 (-4.1A)
None
 1.11A 3abmA-1xajA:
undetectable
3abmC-1xajA:
undetectable
3abmP-1xajA:
undetectable		 3abmA-1xajA:
22.14
3abmC-1xajA:
22.31
3abmP-1xajA:
22.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AOD_C_RFPC2002_1
(ACRIFLAVINE
RESISTANCE PROTEIN B)		 1xaj 3-DEHYDROQUINATE
SYNTHASE
(Staphylococcus
aureus) 		5 / 12 GLN A 232
ALA A 227
PHE A 151
GLY A 233
LEU A 238
 None
None
None
None
CRB  A 500 (-4.1A)
 1.42A 3aodC-1xajA:
undetectable		 3aodC-1xajA:
17.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASN_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1xaj 3-DEHYDROQUINATE
SYNTHASE
(Staphylococcus
aureus) 		4 / 8 LEU A 204
HIS A 242
TYR A 180
HIS A 246
 None
CRB  A 500 ( 3.9A)
None
CRB  A 500 (-4.1A)
 1.12A 3asnC-1xajA:
undetectable
3asnN-1xajA:
undetectable
3asnP-1xajA:
undetectable		 3asnC-1xajA:
22.31
3asnN-1xajA:
22.14
3asnP-1xajA:
22.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASO_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1xaj 3-DEHYDROQUINATE
SYNTHASE
(Staphylococcus
aureus) 		4 / 8 HIS A 242
TYR A 180
HIS A 246
LEU A 204
 CRB  A 500 ( 3.9A)
None
CRB  A 500 (-4.1A)
None
 1.16A 3asoA-1xajA:
undetectable
3asoC-1xajA:
undetectable
3asoP-1xajA:
undetectable		 3asoA-1xajA:
22.14
3asoC-1xajA:
22.31
3asoP-1xajA:
22.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASO_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1xaj 3-DEHYDROQUINATE
SYNTHASE
(Staphylococcus
aureus) 		4 / 8 LEU A 204
HIS A 242
TYR A 180
HIS A 246
 None
CRB  A 500 ( 3.9A)
None
CRB  A 500 (-4.1A)
 1.14A 3asoC-1xajA:
undetectable
3asoN-1xajA:
undetectable
3asoP-1xajA:
undetectable		 3asoC-1xajA:
22.31
3asoN-1xajA:
22.14
3asoP-1xajA:
22.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ELW_A_SAMA4633_0
(METHYLTRANSFERASE)		 1dqs PROTEIN
(3-DEHYDROQUINATE
SYNTHASE)
(Aspergillus
nidulans) 		6 / 12 GLY A 118
GLY A 150
GLY A 122
LEU A 267
VAL A 254
ILE A 149
 None
None
None
CRB  A 401 (-4.1A)
None
None
 1.47A 3elwA-1dqsA:
undetectable		 3elwA-1dqsA:
20.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WG7_C_CHDC306_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1xaj 3-DEHYDROQUINATE
SYNTHASE
(Staphylococcus
aureus) 		4 / 8 HIS A 242
TYR A 180
HIS A 246
LEU A 204
 CRB  A 500 ( 3.9A)
None
CRB  A 500 (-4.1A)
None
 1.11A 3wg7A-1xajA:
undetectable
3wg7C-1xajA:
undetectable
3wg7P-1xajA:
undetectable		 3wg7A-1xajA:
22.14
3wg7C-1xajA:
22.31
3wg7P-1xajA:
22.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WG7_C_CHDC306_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1xaj 3-DEHYDROQUINATE
SYNTHASE
(Staphylococcus
aureus) 		4 / 8 HIS A 242
TYR A 180
HIS A 246
LEU A 291
 CRB  A 500 ( 3.9A)
None
CRB  A 500 (-4.1A)
None
 1.21A 3wg7A-1xajA:
undetectable
3wg7C-1xajA:
undetectable
3wg7P-1xajA:
undetectable		 3wg7A-1xajA:
22.14
3wg7C-1xajA:
22.31
3wg7P-1xajA:
22.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WG7_P_CHDP307_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1xaj 3-DEHYDROQUINATE
SYNTHASE
(Staphylococcus
aureus) 		4 / 8 LEU A 204
HIS A 242
TYR A 180
HIS A 246
 None
CRB  A 500 ( 3.9A)
None
CRB  A 500 (-4.1A)
 1.09A 3wg7C-1xajA:
undetectable
3wg7N-1xajA:
undetectable
3wg7P-1xajA:
undetectable		 3wg7C-1xajA:
22.31
3wg7N-1xajA:
22.14
3wg7P-1xajA:
22.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3X2Q_C_CHDC305_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1xaj 3-DEHYDROQUINATE
SYNTHASE
(Staphylococcus
aureus) 		4 / 8 HIS A 242
TYR A 180
HIS A 246
LEU A 204
 CRB  A 500 ( 3.9A)
None
CRB  A 500 (-4.1A)
None
 1.14A 3x2qA-1xajA:
undetectable
3x2qC-1xajA:
undetectable
3x2qP-1xajA:
undetectable		 3x2qA-1xajA:
22.14
3x2qC-1xajA:
22.31
3x2qP-1xajA:
22.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3X2Q_C_CHDC305_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1xaj 3-DEHYDROQUINATE
SYNTHASE
(Staphylococcus
aureus) 		4 / 8 HIS A 242
TYR A 180
HIS A 246
LEU A 291
 CRB  A 500 ( 3.9A)
None
CRB  A 500 (-4.1A)
None
 1.20A 3x2qA-1xajA:
undetectable
3x2qC-1xajA:
undetectable
3x2qP-1xajA:
undetectable		 3x2qA-1xajA:
22.14
3x2qC-1xajA:
22.31
3x2qP-1xajA:
22.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3X2Q_P_CHDP308_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1xaj 3-DEHYDROQUINATE
SYNTHASE
(Staphylococcus
aureus) 		4 / 8 LEU A 204
HIS A 242
TYR A 180
HIS A 246
 None
CRB  A 500 ( 3.9A)
None
CRB  A 500 (-4.1A)
 1.09A 3x2qC-1xajA:
undetectable
3x2qN-1xajA:
undetectable
3x2qP-1xajA:
undetectable		 3x2qC-1xajA:
22.31
3x2qN-1xajA:
22.14
3x2qP-1xajA:
22.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HVR_A_SALA203_1
(3-HYDROXYANTHRANILAT
E 3,4-DIOXYGENASE)		 1xaj 3-DEHYDROQUINATE
SYNTHASE
(Staphylococcus
aureus) 		4 / 7 HIS A 182
ASP A 130
GLU A 178
VAL A 260
 None
CRB  A 500 ( 3.2A)
ZN  A 600 ( 3.1A)
None
 1.11A 4hvrA-1xajA:
undetectable		 4hvrA-1xajA:
18.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PGF_A_ADNA502_1
(ADENOSYLHOMOCYSTEINA
SE)		 1dqs PROTEIN
(3-DEHYDROQUINATE
SYNTHASE)
(Aspergillus
nidulans) 		5 / 12 LEU A 142
ASP A 146
GLU A 194
ASN A 162
HIS A 275
 NAD  A 400 (-3.7A)
CRB  A 401 ( 2.9A)
ZN  A 402 (-2.4A)
NAD  A 400 (-3.7A)
CRB  A 401 (-4.2A)
 1.36A 4pgfA-1dqsA:
3.7		 4pgfA-1dqsA:
24.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PGF_A_ADNA502_1
(ADENOSYLHOMOCYSTEINA
SE)		 1xaj 3-DEHYDROQUINATE
SYNTHASE
(Staphylococcus
aureus) 		5 / 12 LEU A 127
ASP A 130
GLU A 178
ASN A 146
HIS A 246
 NAD  A 400 (-3.6A)
CRB  A 500 ( 3.2A)
ZN  A 600 ( 3.1A)
NAD  A 400 ( 3.4A)
CRB  A 500 (-4.1A)
 1.33A 4pgfA-1xajA:
2.0		 4pgfA-1xajA:
22.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1A_C_CHDC305_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1xaj 3-DEHYDROQUINATE
SYNTHASE
(Staphylococcus
aureus) 		4 / 8 HIS A 242
TYR A 180
HIS A 246
LEU A 204
 CRB  A 500 ( 3.9A)
None
CRB  A 500 (-4.1A)
None
 1.12A 5b1aA-1xajA:
undetectable
5b1aC-1xajA:
undetectable
5b1aP-1xajA:
undetectable		 5b1aA-1xajA:
22.14
5b1aC-1xajA:
22.31
5b1aP-1xajA:
22.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1A_C_CHDC305_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1xaj 3-DEHYDROQUINATE
SYNTHASE
(Staphylococcus
aureus) 		4 / 8 HIS A 242
TYR A 180
HIS A 246
LEU A 291
 CRB  A 500 ( 3.9A)
None
CRB  A 500 (-4.1A)
None
 1.22A 5b1aA-1xajA:
undetectable
5b1aC-1xajA:
undetectable
5b1aP-1xajA:
undetectable		 5b1aA-1xajA:
22.14
5b1aC-1xajA:
22.31
5b1aP-1xajA:
22.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B3S_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1xaj 3-DEHYDROQUINATE
SYNTHASE
(Staphylococcus
aureus) 		4 / 8 HIS A 242
TYR A 180
HIS A 246
LEU A 204
 CRB  A 500 ( 3.9A)
None
CRB  A 500 (-4.1A)
None
 1.14A 5b3sA-1xajA:
undetectable
5b3sC-1xajA:
undetectable
5b3sP-1xajA:
undetectable		 5b3sA-1xajA:
22.14
5b3sC-1xajA:
22.31
5b3sP-1xajA:
22.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IY5_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1xaj 3-DEHYDROQUINATE
SYNTHASE
(Staphylococcus
aureus) 		4 / 8 LEU A 204
HIS A 242
TYR A 180
HIS A 246
 None
CRB  A 500 ( 3.9A)
None
CRB  A 500 (-4.1A)
 1.13A 5iy5C-1xajA:
undetectable
5iy5N-1xajA:
undetectable
5iy5P-1xajA:
undetectable		 5iy5C-1xajA:
22.04
5iy5N-1xajA:
22.14
5iy5P-1xajA:
22.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N9X_A_THRA601_0
(ADENYLATION DOMAIN)		 1dqs PROTEIN
(3-DEHYDROQUINATE
SYNTHASE)
(Aspergillus
nidulans) 		4 / 7 ASP A 355
GLY A 270
GLY A 274
HIS A 275
 None
None
None
CRB  A 401 (-4.2A)
 1.00A 5n9xA-1dqsA:
undetectable		 5n9xA-1dqsA:
24.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5W97_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1xaj 3-DEHYDROQUINATE
SYNTHASE
(Staphylococcus
aureus) 		4 / 8 HIS A 242
TYR A 180
HIS A 246
LEU A 204
 CRB  A 500 ( 3.9A)
None
CRB  A 500 (-4.1A)
None
 1.10A 5w97A-1xajA:
undetectable
5w97C-1xajA:
undetectable
5w97c-1xajA:
undetectable		 5w97A-1xajA:
22.14
5w97C-1xajA:
22.31
5w97c-1xajA:
22.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5W97_C_CHDC302_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1xaj 3-DEHYDROQUINATE
SYNTHASE
(Staphylococcus
aureus) 		4 / 7 LEU A 204
HIS A 242
TYR A 180
HIS A 246
 None
CRB  A 500 ( 3.9A)
None
CRB  A 500 (-4.1A)
 1.09A 5w97C-1xajA:
undetectable
5w97a-1xajA:
undetectable
5w97c-1xajA:
undetectable		 5w97C-1xajA:
22.31
5w97a-1xajA:
22.14
5w97c-1xajA:
22.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WAU_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1xaj 3-DEHYDROQUINATE
SYNTHASE
(Staphylococcus
aureus) 		4 / 8 HIS A 242
TYR A 180
HIS A 246
LEU A 204
 CRB  A 500 ( 3.9A)
None
CRB  A 500 (-4.1A)
None
 1.11A 5wauA-1xajA:
undetectable
5wauC-1xajA:
0.0
5wauc-1xajA:
0.0		 5wauA-1xajA:
22.14
5wauC-1xajA:
22.31
5wauc-1xajA:
22.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WAU_C_CHDC303_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1xaj 3-DEHYDROQUINATE
SYNTHASE
(Staphylococcus
aureus) 		4 / 7 LEU A 204
HIS A 242
TYR A 180
HIS A 246
 None
CRB  A 500 ( 3.9A)
None
CRB  A 500 (-4.1A)
 1.10A 5wauC-1xajA:
0.0
5waua-1xajA:
undetectable
5wauc-1xajA:
0.0		 5wauC-1xajA:
22.31
5waua-1xajA:
22.14
5wauc-1xajA:
22.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X19_C_CHDC305_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1xaj 3-DEHYDROQUINATE
SYNTHASE
(Staphylococcus
aureus) 		4 / 8 HIS A 242
TYR A 180
HIS A 246
LEU A 204
 CRB  A 500 ( 3.9A)
None
CRB  A 500 (-4.1A)
None
 1.14A 5x19A-1xajA:
undetectable
5x19C-1xajA:
undetectable
5x19P-1xajA:
undetectable		 5x19A-1xajA:
22.14
5x19C-1xajA:
22.31
5x19P-1xajA:
22.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1B_C_CHDC305_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1xaj 3-DEHYDROQUINATE
SYNTHASE
(Staphylococcus
aureus) 		4 / 7 HIS A 242
TYR A 180
HIS A 246
LEU A 204
 CRB  A 500 ( 3.9A)
None
CRB  A 500 (-4.1A)
None
 1.11A 5x1bA-1xajA:
undetectable
5x1bC-1xajA:
undetectable
5x1bP-1xajA:
undetectable		 5x1bA-1xajA:
22.14
5x1bC-1xajA:
22.31
5x1bP-1xajA:
22.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1F_C_CHDC305_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1xaj 3-DEHYDROQUINATE
SYNTHASE
(Staphylococcus
aureus) 		4 / 7 HIS A 242
TYR A 180
HIS A 246
LEU A 204
 CRB  A 500 ( 3.9A)
None
CRB  A 500 (-4.1A)
None
 1.13A 5x1fA-1xajA:
undetectable
5x1fC-1xajA:
undetectable
5x1fP-1xajA:
undetectable		 5x1fA-1xajA:
22.14
5x1fC-1xajA:
22.31
5x1fP-1xajA:
22.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDQ_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1xaj 3-DEHYDROQUINATE
SYNTHASE
(Staphylococcus
aureus) 		4 / 8 HIS A 242
TYR A 180
HIS A 246
LEU A 204
 CRB  A 500 ( 3.9A)
None
CRB  A 500 (-4.1A)
None
 1.11A 5xdqA-1xajA:
undetectable
5xdqC-1xajA:
undetectable
5xdqP-1xajA:
undetectable		 5xdqA-1xajA:
22.14
5xdqC-1xajA:
22.31
5xdqP-1xajA:
22.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDQ_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1xaj 3-DEHYDROQUINATE
SYNTHASE
(Staphylococcus
aureus) 		4 / 8 HIS A 242
TYR A 180
HIS A 246
LEU A 291
 CRB  A 500 ( 3.9A)
None
CRB  A 500 (-4.1A)
None
 1.21A 5xdqA-1xajA:
undetectable
5xdqC-1xajA:
undetectable
5xdqP-1xajA:
undetectable		 5xdqA-1xajA:
22.14
5xdqC-1xajA:
22.31
5xdqP-1xajA:
22.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDQ_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1xaj 3-DEHYDROQUINATE
SYNTHASE
(Staphylococcus
aureus) 		4 / 8 LEU A 204
HIS A 242
TYR A 180
HIS A 246
 None
CRB  A 500 ( 3.9A)
None
CRB  A 500 (-4.1A)
 1.09A 5xdqC-1xajA:
undetectable
5xdqN-1xajA:
undetectable
5xdqP-1xajA:
undetectable		 5xdqC-1xajA:
22.31
5xdqN-1xajA:
22.14
5xdqP-1xajA:
22.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDX_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1xaj 3-DEHYDROQUINATE
SYNTHASE
(Staphylococcus
aureus) 		4 / 8 LEU A 204
HIS A 242
TYR A 180
HIS A 246
 None
CRB  A 500 ( 3.9A)
None
CRB  A 500 (-4.1A)
 1.12A 5xdxC-1xajA:
undetectable
5xdxN-1xajA:
undetectable
5xdxP-1xajA:
undetectable		 5xdxC-1xajA:
21.56
5xdxN-1xajA:
22.14
5xdxP-1xajA:
21.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z84_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1xaj 3-DEHYDROQUINATE
SYNTHASE
(Staphylococcus
aureus) 		4 / 8 HIS A 242
TYR A 180
HIS A 246
LEU A 204
 CRB  A 500 ( 3.9A)
None
CRB  A 500 (-4.1A)
None
 1.10A 5z84A-1xajA:
undetectable
5z84C-1xajA:
undetectable
5z84P-1xajA:
undetectable		 5z84A-1xajA:
22.14
5z84C-1xajA:
22.31
5z84P-1xajA:
22.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z84_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1xaj 3-DEHYDROQUINATE
SYNTHASE
(Staphylococcus
aureus) 		4 / 7 LEU A 204
HIS A 242
TYR A 180
HIS A 246
 None
CRB  A 500 ( 3.9A)
None
CRB  A 500 (-4.1A)
 1.09A 5z84C-1xajA:
undetectable
5z84N-1xajA:
undetectable
5z84P-1xajA:
undetectable		 5z84C-1xajA:
22.31
5z84N-1xajA:
22.14
5z84P-1xajA:
22.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z85_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1xaj 3-DEHYDROQUINATE
SYNTHASE
(Staphylococcus
aureus) 		4 / 8 HIS A 242
TYR A 180
HIS A 246
LEU A 204
 CRB  A 500 ( 3.9A)
None
CRB  A 500 (-4.1A)
None
 1.10A 5z85A-1xajA:
undetectable
5z85C-1xajA:
undetectable
5z85P-1xajA:
undetectable		 5z85A-1xajA:
22.14
5z85C-1xajA:
22.31
5z85P-1xajA:
22.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z85_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1xaj 3-DEHYDROQUINATE
SYNTHASE
(Staphylococcus
aureus) 		4 / 7 LEU A 204
HIS A 242
TYR A 180
HIS A 246
 None
CRB  A 500 ( 3.9A)
None
CRB  A 500 (-4.1A)
 1.12A 5z85C-1xajA:
undetectable
5z85N-1xajA:
undetectable
5z85P-1xajA:
undetectable		 5z85C-1xajA:
22.31
5z85N-1xajA:
22.14
5z85P-1xajA:
22.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z86_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1xaj 3-DEHYDROQUINATE
SYNTHASE
(Staphylococcus
aureus) 		4 / 8 HIS A 242
TYR A 180
HIS A 246
LEU A 204
 CRB  A 500 ( 3.9A)
None
CRB  A 500 (-4.1A)
None
 1.13A 5z86A-1xajA:
undetectable
5z86C-1xajA:
undetectable
5z86P-1xajA:
undetectable		 5z86A-1xajA:
22.14
5z86C-1xajA:
22.31
5z86P-1xajA:
22.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z86_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1xaj 3-DEHYDROQUINATE
SYNTHASE
(Staphylococcus
aureus) 		4 / 8 LEU A 204
HIS A 242
TYR A 180
HIS A 246
 None
CRB  A 500 ( 3.9A)
None
CRB  A 500 (-4.1A)
 1.11A 5z86C-1xajA:
undetectable
5z86N-1xajA:
undetectable
5z86P-1xajA:
undetectable		 5z86C-1xajA:
22.31
5z86N-1xajA:
22.14
5z86P-1xajA:
22.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCO_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1xaj 3-DEHYDROQUINATE
SYNTHASE
(Staphylococcus
aureus) 		4 / 8 HIS A 242
TYR A 180
HIS A 246
LEU A 204
 CRB  A 500 ( 3.9A)
None
CRB  A 500 (-4.1A)
None
 1.11A 5zcoA-1xajA:
undetectable
5zcoC-1xajA:
undetectable
5zcoP-1xajA:
undetectable		 5zcoA-1xajA:
22.14
5zcoC-1xajA:
22.31
5zcoP-1xajA:
22.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCO_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1xaj 3-DEHYDROQUINATE
SYNTHASE
(Staphylococcus
aureus) 		4 / 8 HIS A 242
TYR A 180
HIS A 246
LEU A 291
 CRB  A 500 ( 3.9A)
None
CRB  A 500 (-4.1A)
None
 1.21A 5zcoA-1xajA:
undetectable
5zcoC-1xajA:
undetectable
5zcoP-1xajA:
undetectable		 5zcoA-1xajA:
22.14
5zcoC-1xajA:
22.31
5zcoP-1xajA:
22.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCO_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1xaj 3-DEHYDROQUINATE
SYNTHASE
(Staphylococcus
aureus) 		4 / 8 LEU A 204
HIS A 242
TYR A 180
HIS A 246
 None
CRB  A 500 ( 3.9A)
None
CRB  A 500 (-4.1A)
 1.08A 5zcoC-1xajA:
undetectable
5zcoN-1xajA:
undetectable
5zcoP-1xajA:
undetectable		 5zcoC-1xajA:
22.31
5zcoN-1xajA:
22.14
5zcoP-1xajA:
22.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCP_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1xaj 3-DEHYDROQUINATE
SYNTHASE
(Staphylococcus
aureus) 		4 / 8 HIS A 242
TYR A 180
HIS A 246
LEU A 204
 CRB  A 500 ( 3.9A)
None
CRB  A 500 (-4.1A)
None
 1.09A 5zcpA-1xajA:
undetectable
5zcpC-1xajA:
undetectable
5zcpP-1xajA:
undetectable		 5zcpA-1xajA:
22.14
5zcpC-1xajA:
22.31
5zcpP-1xajA:
22.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCP_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1xaj 3-DEHYDROQUINATE
SYNTHASE
(Staphylococcus
aureus) 		4 / 8 LEU A 204
HIS A 242
TYR A 180
HIS A 246
 None
CRB  A 500 ( 3.9A)
None
CRB  A 500 (-4.1A)
 1.10A 5zcpC-1xajA:
undetectable
5zcpN-1xajA:
undetectable
5zcpP-1xajA:
undetectable		 5zcpC-1xajA:
22.31
5zcpN-1xajA:
22.14
5zcpP-1xajA:
22.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCQ_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1xaj 3-DEHYDROQUINATE
SYNTHASE
(Staphylococcus
aureus) 		4 / 8 HIS A 242
TYR A 180
HIS A 246
LEU A 204
 CRB  A 500 ( 3.9A)
None
CRB  A 500 (-4.1A)
None
 1.11A 5zcqA-1xajA:
undetectable
5zcqC-1xajA:
undetectable
5zcqP-1xajA:
undetectable		 5zcqA-1xajA:
22.14
5zcqC-1xajA:
22.31
5zcqP-1xajA:
22.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCQ_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1xaj 3-DEHYDROQUINATE
SYNTHASE
(Staphylococcus
aureus) 		4 / 8 HIS A 242
TYR A 180
HIS A 246
LEU A 291
 CRB  A 500 ( 3.9A)
None
CRB  A 500 (-4.1A)
None
 1.22A 5zcqA-1xajA:
undetectable
5zcqC-1xajA:
undetectable
5zcqP-1xajA:
undetectable		 5zcqA-1xajA:
22.14
5zcqC-1xajA:
22.31
5zcqP-1xajA:
22.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NKN_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1xaj 3-DEHYDROQUINATE
SYNTHASE
(Staphylococcus
aureus) 		4 / 8 LEU A 204
HIS A 242
TYR A 180
HIS A 246
 None
CRB  A 500 ( 3.9A)
None
CRB  A 500 (-4.1A)
 1.06A 6nknC-1xajA:
undetectable
6nknN-1xajA:
undetectable
6nknP-1xajA:
undetectable		 6nknC-1xajA:
22.31
6nknN-1xajA:
22.14
6nknP-1xajA:
22.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMF_C_CHDC306_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 1xaj 3-DEHYDROQUINATE
SYNTHASE
(Staphylococcus
aureus) 		4 / 7 HIS A 242
TYR A 180
HIS A 246
LEU A 204
 CRB  A 500 ( 3.9A)
None
CRB  A 500 (-4.1A)
None
 1.13A 6nmfA-1xajA:
undetectable
6nmfC-1xajA:
undetectable
6nmfP-1xajA:
undetectable		 6nmfA-1xajA:
22.14
6nmfC-1xajA:
22.31
6nmfP-1xajA:
22.31