SIMILAR PATTERN OF AMINO ACIDS MAPPED TO 'CR7'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1NOD_B_H4BB902_1 (NITRIC OXIDE SYNTHASE)	2a46	GFP-LIKE FLUORESCENT CHROMOPROTEIN AMFP486 (Anemonia majano)	3 / 3	ARG A 72 ILE A 113 TRP A 111	CR7 A 68 ( 4.4A) None CR7 A 68 ( 4.1A)	0.95A	1nodB-2a46A: undetectable	1nodB-2a46A: 20.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1QOM_A_H4BA902_1 (NITRIC OXIDE SYNTHASE)	2a46	GFP-LIKE FLUORESCENT CHROMOPROTEIN AMFP486 (Anemonia majano)	3 / 3	ARG A 72 ILE A 113 TRP A 111	CR7 A 68 ( 4.4A) None CR7 A 68 ( 4.1A)	0.93A	1qomA-2a46A: undetectable	1qomA-2a46A: 20.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2NOD_B_H4BB902_1 (NITRIC OXIDE SYNTHASE)	2a46	GFP-LIKE FLUORESCENT CHROMOPROTEIN AMFP486 (Anemonia majano)	3 / 3	ARG A 72 ILE A 113 TRP A 111	CR7 A 68 ( 4.4A) None CR7 A 68 ( 4.1A)	0.92A	2nodB-2a46A: undetectable	2nodB-2a46A: 20.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2XKK_E_MFXE1100_1 (TOPOISOMERASE IV DNA)	2a46	GFP-LIKE FLUORESCENT CHROMOPROTEIN AMFP486 (Anemonia majano)	3 / 3	ARG A 200 GLU A 39 SER A 148	None None CR7 A 68 ( 2.5A)	0.90A	2xkkA-2a46A: undetectable 2xkkC-2a46A: undetectable	2xkkA-2a46A: 14.90 2xkkC-2a46A: 14.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3E7I_B_H4BB2902_1 (NITRIC OXIDE SYNTHASE, INDUCIBLE)	2a46	GFP-LIKE FLUORESCENT CHROMOPROTEIN AMFP486 (Anemonia majano)	3 / 3	ARG A 72 ILE A 113 TRP A 111	CR7 A 68 ( 4.4A) None CR7 A 68 ( 4.1A)	0.92A	3e7iB-2a46A: undetectable	3e7iB-2a46A: 20.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3NW2_A_H4BA902_1 (NITRIC OXIDE SYNTHASE, INDUCIBLE)	2a46	GFP-LIKE FLUORESCENT CHROMOPROTEIN AMFP486 (Anemonia majano)	3 / 3	ARG A 72 ILE A 113 TRP A 111	CR7 A 68 ( 4.4A) None CR7 A 68 ( 4.1A)	0.96A	3nw2A-2a46A: undetectable	3nw2A-2a46A: 20.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3NW2_B_H4BB902_1 (NITRIC OXIDE SYNTHASE, INDUCIBLE)	2a46	GFP-LIKE FLUORESCENT CHROMOPROTEIN AMFP486 (Anemonia majano)	3 / 3	ARG A 72 ILE A 113 TRP A 111	CR7 A 68 ( 4.4A) None CR7 A 68 ( 4.1A)	0.90A	3nw2B-2a46A: undetectable	3nw2B-2a46A: 20.82

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1NOD_B_H4BB902_1","NITRIC OXIDE SYNTHASE","2a46","GFP-LIKE FLUORESCENT CHROMOPROTEIN AMFP486","Anemonia majano",3,"ARG A  72;ILE A 113;TRP A 111","CR7 A  68 ( 4.4A);None;CR7 A  68 ( 4.1A)","0.95A","1nodB-2a46A:undetectable",null],["1QOM_A_H4BA902_1","NITRIC OXIDE SYNTHASE","2a46","GFP-LIKE FLUORESCENT CHROMOPROTEIN AMFP486","Anemonia majano",3,"ARG A  72;ILE A 113;TRP A 111","CR7 A  68 ( 4.4A);None;CR7 A  68 ( 4.1A)","0.93A","1qomA-2a46A:undetectable","1nodB-2a46A:20.82"],["2NOD_B_H4BB902_1","NITRIC OXIDE SYNTHASE","2a46","GFP-LIKE FLUORESCENT CHROMOPROTEIN AMFP486","Anemonia majano",3,"ARG A  72;ILE A 113;TRP A 111","CR7 A  68 ( 4.4A);None;CR7 A  68 ( 4.1A)","0.92A","2nodB-2a46A:undetectable","1qomA-2a46A:20.24"],["2XKK_E_MFXE1100_1","TOPOISOMERASE IV;TOPOISOMERASE IV;DNA","2a46","GFP-LIKE FLUORESCENT CHROMOPROTEIN AMFP486","Anemonia majano",3,"ARG A 200;GLU A  39;SER A 148","None;None;CR7 A  68 ( 2.5A)","0.90A","2xkkA-2a46A:undetectable;2xkkC-2a46A:undetectable","2nodB-2a46A:20.82"],["3E7I_B_H4BB2902_1","NITRIC OXIDE SYNTHASE, INDUCIBLE","2a46","GFP-LIKE FLUORESCENT CHROMOPROTEIN AMFP486","Anemonia majano",3,"ARG A  72;ILE A 113;TRP A 111","CR7 A  68 ( 4.4A);None;CR7 A  68 ( 4.1A)","0.92A","3e7iB-2a46A:undetectable","2xkkA-2a46A:14.90;2xkkC-2a46A:14.90"],["3NW2_A_H4BA902_1","NITRIC OXIDE SYNTHASE, INDUCIBLE","2a46","GFP-LIKE FLUORESCENT CHROMOPROTEIN AMFP486","Anemonia majano",3,"ARG A  72;ILE A 113;TRP A 111","CR7 A  68 ( 4.4A);None;CR7 A  68 ( 4.1A)","0.96A","3nw2A-2a46A:undetectable","3e7iB-2a46A:20.28"],["3NW2_B_H4BB902_1","NITRIC OXIDE SYNTHASE, INDUCIBLE","2a46","GFP-LIKE FLUORESCENT CHROMOPROTEIN AMFP486","Anemonia majano",3,"ARG A  72;ILE A 113;TRP A 111","CR7 A  68 ( 4.4A);None;CR7 A  68 ( 4.1A)","0.90A","3nw2B-2a46A:undetectable","3nw2A-2a46A:20.82"]]