SIMILAR PATTERN OF AMINO ACIDS MAPPED TO 'CPZ'


List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2NNH_A_9CRA501_1
(CYTOCHROME P450 2C8)		 3tk3 CYTOCHROME P450 2B4
(Oryctolagus
cuniculus) 		6 / 11 ARG A  98
ILE A 114
ALA A 298
THR A 302
VAL A 367
PRO A 368
 HEM  A 500 (-2.9A)
HEM  A 500 (-4.0A)
CPZ  A 501 (-3.5A)
CPZ  A 501 ( 3.7A)
HEM  A 500 ( 4.3A)
None
 0.76A 2nnhA-3tk3A:
52.7		 2nnhA-3tk3A:
55.46
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2NNH_A_9CRA501_1
(CYTOCHROME P450 2C8)		 5e0e CYTOCHROME P450
FAMILY 2 SUBFAMILY B
(Neotoma
lepida) 		5 / 11 ARG A  98
ALA A 298
THR A 302
VAL A 367
PRO A 368
 HEM  A 501 (-2.7A)
HEM  A 501 ( 3.1A)
CPZ  A 502 ( 4.0A)
HEM  A 501 ( 4.4A)
None
 0.77A 2nnhA-5e0eA:
52.2		 2nnhA-5e0eA:
52.75
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2NNH_B_9CRB501_1
(CYTOCHROME P450 2C8)		 3tk3 CYTOCHROME P450 2B4
(Oryctolagus
cuniculus) 		5 / 9 ARG A  98
ILE A 114
THR A 302
VAL A 367
PRO A 368
 HEM  A 500 (-2.9A)
HEM  A 500 (-4.0A)
CPZ  A 501 ( 3.7A)
HEM  A 500 ( 4.3A)
None
 0.69A 2nnhB-3tk3A:
45.9		 2nnhB-3tk3A:
55.46
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2NNJ_A_225A501_1
(CYTOCHROME P450 2C8)		 3tk3 CYTOCHROME P450 2B4
(Oryctolagus
cuniculus) 		5 / 10 ILE A 114
ALA A 298
THR A 302
VAL A 367
PRO A 368
 HEM  A 500 (-4.0A)
CPZ  A 501 (-3.5A)
CPZ  A 501 ( 3.7A)
HEM  A 500 ( 4.3A)
None
 0.75A 2nnjA-3tk3A:
53.6		 2nnjA-3tk3A:
55.46
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3E4E_A_4PZA501_1
(CYTOCHROME P450 2E1)		 3tk3 CYTOCHROME P450 2B4
(Oryctolagus
cuniculus) 		3 / 3 ALA A 298
THR A 302
CYH A 436
 CPZ  A 501 (-3.5A)
CPZ  A 501 ( 3.7A)
HEM  A 500 (-2.3A)
 0.61A 3e4eA-3tk3A:
48.5		 3e4eA-3tk3A:
49.58
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3E4E_B_4PZB501_1
(CYTOCHROME P450 2E1)		 3tk3 CYTOCHROME P450 2B4
(Oryctolagus
cuniculus) 		3 / 3 ALA A 298
THR A 302
CYH A 436
 CPZ  A 501 (-3.5A)
CPZ  A 501 ( 3.7A)
HEM  A 500 (-2.3A)
 0.55A 3e4eB-3tk3A:
54.3		 3e4eB-3tk3A:
49.58
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3KW4_A_TICA600_1
(CYTOCHROME P450 2B4)		 3tk3 CYTOCHROME P450 2B4
(Oryctolagus
cuniculus) 		9 / 11 ILE A 114
ILE A 209
PHE A 297
ALA A 298
THR A 302
ILE A 363
VAL A 367
VAL A 477
GLY A 478
 HEM  A 500 (-4.0A)
None
CPZ  A 501 (-4.3A)
CPZ  A 501 (-3.5A)
CPZ  A 501 ( 3.7A)
HEM  A 500 ( 3.9A)
HEM  A 500 ( 4.3A)
None
None
 0.64A 3kw4A-3tk3A:
60.2		 3kw4A-3tk3A:
99.79
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3KW4_A_TICA600_1
(CYTOCHROME P450 2B4)		 3tk3 CYTOCHROME P450 2B4
(Oryctolagus
cuniculus) 		9 / 11 ILE A 114
ILE A 209
SER A 210
PHE A 297
ALA A 298
THR A 302
VAL A 367
VAL A 477
GLY A 478
 HEM  A 500 (-4.0A)
None
None
CPZ  A 501 (-4.3A)
CPZ  A 501 (-3.5A)
CPZ  A 501 ( 3.7A)
HEM  A 500 ( 4.3A)
None
None
 0.72A 3kw4A-3tk3A:
60.2		 3kw4A-3tk3A:
99.79
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3KW4_A_TICA600_1
(CYTOCHROME P450 2B4)		 5e0e CYTOCHROME P450
FAMILY 2 SUBFAMILY B
(Neotoma
lepida) 		7 / 11 ILE A 209
PHE A 297
ALA A 298
GLU A 301
THR A 302
ILE A 363
VAL A 367
 None
None
HEM  A 501 ( 3.1A)
None
CPZ  A 502 ( 4.0A)
HEM  A 501 (-4.1A)
HEM  A 501 ( 4.4A)
 0.88A 3kw4A-5e0eA:
54.6		 3kw4A-5e0eA:
79.87
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3KW4_A_TICA600_1
(CYTOCHROME P450 2B4)		 5e0e CYTOCHROME P450
FAMILY 2 SUBFAMILY B
(Neotoma
lepida) 		7 / 11 ILE A 209
SER A 210
PHE A 297
ALA A 298
GLU A 301
THR A 302
VAL A 367
 None
None
None
HEM  A 501 ( 3.1A)
None
CPZ  A 502 ( 4.0A)
HEM  A 501 ( 4.4A)
 1.03A 3kw4A-5e0eA:
54.6		 3kw4A-5e0eA:
79.87
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3ME6_A_CGEA501_1
(CYTOCHROME P450 2B4)		 3tk3 CYTOCHROME P450 2B4
(Oryctolagus
cuniculus) 		8 / 10 VAL A 104
PHE A 108
ILE A 209
ALA A 298
THR A 302
ILE A 363
VAL A 367
VAL A 477
 None
None
None
CPZ  A 501 (-3.5A)
CPZ  A 501 ( 3.7A)
HEM  A 500 ( 3.9A)
HEM  A 500 ( 4.3A)
None
 0.53A 3me6A-3tk3A:
62.9		 3me6A-3tk3A:
99.79
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3ME6_A_CGEA501_1
(CYTOCHROME P450 2B4)		 3tk3 CYTOCHROME P450 2B4
(Oryctolagus
cuniculus) 		6 / 10 VAL A 104
PHE A 108
ILE A 209
PHE A 297
ALA A 298
THR A 302
 None
None
None
CPZ  A 501 (-4.3A)
CPZ  A 501 (-3.5A)
CPZ  A 501 ( 3.7A)
 1.05A 3me6A-3tk3A:
62.9		 3me6A-3tk3A:
99.79
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3ME6_A_CGEA501_1
(CYTOCHROME P450 2B4)		 5e0e CYTOCHROME P450
FAMILY 2 SUBFAMILY B
(Neotoma
lepida) 		6 / 10 ILE A 209
PHE A 297
ALA A 298
THR A 302
ILE A 363
VAL A 367
 None
None
HEM  A 501 ( 3.1A)
CPZ  A 502 ( 4.0A)
HEM  A 501 (-4.1A)
HEM  A 501 ( 4.4A)
 1.08A 3me6A-5e0eA:
53.7		 3me6A-5e0eA:
79.87
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3ME6_A_CGEA501_1
(CYTOCHROME P450 2B4)		 5e0e CYTOCHROME P450
FAMILY 2 SUBFAMILY B
(Neotoma
lepida) 		7 / 10 VAL A 104
PHE A 108
ILE A 209
ALA A 298
THR A 302
ILE A 363
VAL A 367
 None
None
None
HEM  A 501 ( 3.1A)
CPZ  A 502 ( 4.0A)
HEM  A 501 (-4.1A)
HEM  A 501 ( 4.4A)
 1.00A 3me6A-5e0eA:
53.7		 3me6A-5e0eA:
79.87
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3ME6_B_CGEB501_1
(CYTOCHROME P450 2B4)		 3tk3 CYTOCHROME P450 2B4
(Oryctolagus
cuniculus) 		6 / 8 PHE A 108
ILE A 209
ALA A 298
THR A 302
VAL A 367
VAL A 477
 None
None
CPZ  A 501 (-3.5A)
CPZ  A 501 ( 3.7A)
HEM  A 500 ( 4.3A)
None
 0.46A 3me6B-3tk3A:
62.9		 3me6B-3tk3A:
99.79
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3ME6_C_CGEC501_1
(CYTOCHROME P450 2B4)		 3tk3 CYTOCHROME P450 2B4
(Oryctolagus
cuniculus) 		7 / 9 VAL A 104
PHE A 108
ILE A 209
ALA A 298
THR A 302
VAL A 367
VAL A 477
 None
None
None
CPZ  A 501 (-3.5A)
CPZ  A 501 ( 3.7A)
HEM  A 500 ( 4.3A)
None
 0.56A 3me6C-3tk3A:
62.9		 3me6C-3tk3A:
99.79
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3ME6_C_CGEC501_1
(CYTOCHROME P450 2B4)		 3tk3 CYTOCHROME P450 2B4
(Oryctolagus
cuniculus) 		6 / 9 VAL A 104
PHE A 108
ILE A 209
PHE A 297
ALA A 298
THR A 302
 None
None
None
CPZ  A 501 (-4.3A)
CPZ  A 501 (-3.5A)
CPZ  A 501 ( 3.7A)
 1.06A 3me6C-3tk3A:
62.9		 3me6C-3tk3A:
99.79
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3ME6_C_CGEC501_1
(CYTOCHROME P450 2B4)		 5e0e CYTOCHROME P450
FAMILY 2 SUBFAMILY B
(Neotoma
lepida) 		5 / 9 VAL A 104
PHE A 108
ILE A 209
THR A 302
VAL A 367
 None
None
None
CPZ  A 502 ( 4.0A)
HEM  A 501 ( 4.4A)
 0.80A 3me6C-5e0eA:
53.6		 3me6C-5e0eA:
79.87
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3ME6_D_CGED501_1
(CYTOCHROME P450 2B4)		 3tk3 CYTOCHROME P450 2B4
(Oryctolagus
cuniculus) 		5 / 9 PHE A 108
ILE A 209
PHE A 297
ALA A 298
THR A 302
 None
None
CPZ  A 501 (-4.3A)
CPZ  A 501 (-3.5A)
CPZ  A 501 ( 3.7A)
 1.24A 3me6D-3tk3A:
62.9		 3me6D-3tk3A:
99.79
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3ME6_D_CGED501_1
(CYTOCHROME P450 2B4)		 3tk3 CYTOCHROME P450 2B4
(Oryctolagus
cuniculus) 		7 / 9 VAL A 104
PHE A 108
ILE A 209
ALA A 298
THR A 302
VAL A 367
VAL A 477
 None
None
None
CPZ  A 501 (-3.5A)
CPZ  A 501 ( 3.7A)
HEM  A 500 ( 4.3A)
None
 0.38A 3me6D-3tk3A:
62.9		 3me6D-3tk3A:
99.79
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3ME6_D_CGED501_1
(CYTOCHROME P450 2B4)		 5e0e CYTOCHROME P450
FAMILY 2 SUBFAMILY B
(Neotoma
lepida) 		5 / 9 ILE A 209
PHE A 297
ALA A 298
THR A 302
VAL A 367
 None
None
HEM  A 501 ( 3.1A)
CPZ  A 502 ( 4.0A)
HEM  A 501 ( 4.4A)
 1.10A 3me6D-5e0eA:
53.8		 3me6D-5e0eA:
79.87
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3ME6_D_CGED501_1
(CYTOCHROME P450 2B4)		 5e0e CYTOCHROME P450
FAMILY 2 SUBFAMILY B
(Neotoma
lepida) 		6 / 9 VAL A 104
PHE A 108
ILE A 209
ALA A 298
THR A 302
VAL A 367
 None
None
None
HEM  A 501 ( 3.1A)
CPZ  A 502 ( 4.0A)
HEM  A 501 ( 4.4A)
 0.82A 3me6D-5e0eA:
53.8		 3me6D-5e0eA:
79.87
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3T3Q_A_9PLA501_1
(CYTOCHROME P450 2A6)		 3tk3 CYTOCHROME P450 2B4
(Oryctolagus
cuniculus) 		5 / 10 PHE A 108
PHE A 115
ALA A 298
THR A 302
ILE A 363
 None
None
CPZ  A 501 (-3.5A)
CPZ  A 501 ( 3.7A)
HEM  A 500 ( 3.9A)
 0.48A 3t3qA-3tk3A:
56.8		 3t3qA-3tk3A:
56.39
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3T3Q_A_9PLA501_1
(CYTOCHROME P450 2A6)		 5e0e CYTOCHROME P450
FAMILY 2 SUBFAMILY B
(Neotoma
lepida) 		6 / 10 PHE A 108
VAL A 114
PHE A 115
ALA A 298
THR A 302
ILE A 363
 None
HEM  A 501 (-3.5A)
None
HEM  A 501 ( 3.1A)
CPZ  A 502 ( 4.0A)
HEM  A 501 (-4.1A)
 0.83A 3t3qA-5e0eA:
51.7		 3t3qA-5e0eA:
56.78
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3T3Q_A_9PLA501_1
(CYTOCHROME P450 2A6)		 5e0e CYTOCHROME P450
FAMILY 2 SUBFAMILY B
(Neotoma
lepida) 		5 / 10 PHE A 115
PHE A 297
ALA A 298
THR A 302
ILE A 363
 None
None
HEM  A 501 ( 3.1A)
CPZ  A 502 ( 4.0A)
HEM  A 501 (-4.1A)
 1.10A 3t3qA-5e0eA:
51.7		 3t3qA-5e0eA:
56.78
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3T3Q_B_9PLB501_1
(CYTOCHROME P450 2A6)		 3tk3 CYTOCHROME P450 2B4
(Oryctolagus
cuniculus) 		5 / 10 PHE A 108
PHE A 115
ALA A 298
THR A 302
ILE A 363
 None
None
CPZ  A 501 (-3.5A)
CPZ  A 501 ( 3.7A)
HEM  A 500 ( 3.9A)
 0.57A 3t3qB-3tk3A:
56.8		 3t3qB-3tk3A:
56.39
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3T3Q_B_9PLB501_1
(CYTOCHROME P450 2A6)		 3tk3 CYTOCHROME P450 2B4
(Oryctolagus
cuniculus) 		5 / 10 PHE A 108
PHE A 297
ALA A 298
THR A 302
ILE A 363
 None
CPZ  A 501 (-4.3A)
CPZ  A 501 (-3.5A)
CPZ  A 501 ( 3.7A)
HEM  A 500 ( 3.9A)
 1.03A 3t3qB-3tk3A:
56.8		 3t3qB-3tk3A:
56.39
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3T3Q_B_9PLB501_1
(CYTOCHROME P450 2A6)		 5e0e CYTOCHROME P450
FAMILY 2 SUBFAMILY B
(Neotoma
lepida) 		6 / 10 PHE A 108
VAL A 114
PHE A 115
ALA A 298
THR A 302
ILE A 363
 None
HEM  A 501 (-3.5A)
None
HEM  A 501 ( 3.1A)
CPZ  A 502 ( 4.0A)
HEM  A 501 (-4.1A)
 0.90A 3t3qB-5e0eA:
51.7		 3t3qB-5e0eA:
56.78
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3T3Q_B_9PLB501_1
(CYTOCHROME P450 2A6)		 5e0e CYTOCHROME P450
FAMILY 2 SUBFAMILY B
(Neotoma
lepida) 		5 / 10 PHE A 115
PHE A 297
ALA A 298
THR A 302
ILE A 363
 None
None
HEM  A 501 ( 3.1A)
CPZ  A 502 ( 4.0A)
HEM  A 501 (-4.1A)
 1.20A 3t3qB-5e0eA:
51.7		 3t3qB-5e0eA:
56.78
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3T3Q_C_9PLC501_1
(CYTOCHROME P450 2A6)		 3tk3 CYTOCHROME P450 2B4
(Oryctolagus
cuniculus) 		5 / 10 PHE A 108
PHE A 115
ALA A 298
THR A 302
ILE A 363
 None
None
CPZ  A 501 (-3.5A)
CPZ  A 501 ( 3.7A)
HEM  A 500 ( 3.9A)
 0.55A 3t3qC-3tk3A:
56.7		 3t3qC-3tk3A:
56.39
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3T3Q_C_9PLC501_1
(CYTOCHROME P450 2A6)		 3tk3 CYTOCHROME P450 2B4
(Oryctolagus
cuniculus) 		5 / 10 PHE A 108
PHE A 297
ALA A 298
THR A 302
ILE A 363
 None
CPZ  A 501 (-4.3A)
CPZ  A 501 (-3.5A)
CPZ  A 501 ( 3.7A)
HEM  A 500 ( 3.9A)
 1.06A 3t3qC-3tk3A:
56.7		 3t3qC-3tk3A:
56.39
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3T3Q_C_9PLC501_1
(CYTOCHROME P450 2A6)		 5e0e CYTOCHROME P450
FAMILY 2 SUBFAMILY B
(Neotoma
lepida) 		6 / 10 PHE A 108
VAL A 114
PHE A 115
ALA A 298
THR A 302
ILE A 363
 None
HEM  A 501 (-3.5A)
None
HEM  A 501 ( 3.1A)
CPZ  A 502 ( 4.0A)
HEM  A 501 (-4.1A)
 0.90A 3t3qC-5e0eA:
51.7		 3t3qC-5e0eA:
56.78
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3T3Q_C_9PLC501_1
(CYTOCHROME P450 2A6)		 5e0e CYTOCHROME P450
FAMILY 2 SUBFAMILY B
(Neotoma
lepida) 		5 / 10 PHE A 115
PHE A 297
ALA A 298
THR A 302
ILE A 363
 None
None
HEM  A 501 ( 3.1A)
CPZ  A 502 ( 4.0A)
HEM  A 501 (-4.1A)
 1.18A 3t3qC-5e0eA:
51.7		 3t3qC-5e0eA:
56.78
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3T3Q_D_9PLD501_1
(CYTOCHROME P450 2A6)		 3tk3 CYTOCHROME P450 2B4
(Oryctolagus
cuniculus) 		5 / 10 PHE A 108
PHE A 115
ALA A 298
THR A 302
ILE A 363
 None
None
CPZ  A 501 (-3.5A)
CPZ  A 501 ( 3.7A)
HEM  A 500 ( 3.9A)
 0.59A 3t3qD-3tk3A:
56.9		 3t3qD-3tk3A:
56.39
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3T3Q_D_9PLD501_1
(CYTOCHROME P450 2A6)		 3tk3 CYTOCHROME P450 2B4
(Oryctolagus
cuniculus) 		5 / 10 PHE A 108
PHE A 297
ALA A 298
THR A 302
ILE A 363
 None
CPZ  A 501 (-4.3A)
CPZ  A 501 (-3.5A)
CPZ  A 501 ( 3.7A)
HEM  A 500 ( 3.9A)
 1.03A 3t3qD-3tk3A:
56.9		 3t3qD-3tk3A:
56.39
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3T3Q_D_9PLD501_1
(CYTOCHROME P450 2A6)		 5e0e CYTOCHROME P450
FAMILY 2 SUBFAMILY B
(Neotoma
lepida) 		6 / 10 PHE A 108
VAL A 114
PHE A 115
ALA A 298
THR A 302
ILE A 363
 None
HEM  A 501 (-3.5A)
None
HEM  A 501 ( 3.1A)
CPZ  A 502 ( 4.0A)
HEM  A 501 (-4.1A)
 0.93A 3t3qD-5e0eA:
51.8		 3t3qD-5e0eA:
56.78
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3T3R_A_9PLA501_1
(CYTOCHROME P450 2A6)		 5e0e CYTOCHROME P450
FAMILY 2 SUBFAMILY B
(Neotoma
lepida) 		5 / 11 PHE A 108
VAL A 114
PHE A 115
GLY A 299
THR A 302
 None
HEM  A 501 (-3.5A)
None
HEM  A 501 (-3.5A)
CPZ  A 502 ( 4.0A)
 0.93A 3t3rA-5e0eA:
51.5		 3t3rA-5e0eA:
55.93
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3T3S_B_9PLB1_1
(CYTOCHROME P450 2A13)		 3tk3 CYTOCHROME P450 2B4
(Oryctolagus
cuniculus) 		4 / 6 PHE A 115
PHE A 297
ALA A 298
THR A 302
 None
CPZ  A 501 (-4.3A)
CPZ  A 501 (-3.5A)
CPZ  A 501 ( 3.7A)
 1.19A 3t3sB-3tk3A:
55.9		 3t3sB-3tk3A:
56.81
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3T3S_D_9PLD1_1
(CYTOCHROME P450 2A13)		 3tk3 CYTOCHROME P450 2B4
(Oryctolagus
cuniculus) 		4 / 8 PHE A 108
PHE A 115
ALA A 298
THR A 302
 None
None
CPZ  A 501 (-3.5A)
CPZ  A 501 ( 3.7A)
 0.65A 3t3sD-3tk3A:
55.6		 3t3sD-3tk3A:
56.81
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3T3S_F_9PLF1_1
(CYTOCHROME P450 2A13)		 3tk3 CYTOCHROME P450 2B4
(Oryctolagus
cuniculus) 		4 / 8 PHE A 108
PHE A 297
ALA A 298
THR A 302
 None
CPZ  A 501 (-4.3A)
CPZ  A 501 (-3.5A)
CPZ  A 501 ( 3.7A)
 0.97A 3t3sF-3tk3A:
53.7		 3t3sF-3tk3A:
56.81
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3T3Z_A_9PLA501_1
(CYTOCHROME P450 2E1)		 3tk3 CYTOCHROME P450 2B4
(Oryctolagus
cuniculus) 		4 / 6 PHE A 115
PHE A 297
ALA A 298
THR A 302
 None
CPZ  A 501 (-4.3A)
CPZ  A 501 (-3.5A)
CPZ  A 501 ( 3.7A)
 0.61A 3t3zA-3tk3A:
53.9		 3t3zA-3tk3A:
49.58
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3T3Z_B_9PLB501_1
(CYTOCHROME P450 2E1)		 3tk3 CYTOCHROME P450 2B4
(Oryctolagus
cuniculus) 		4 / 6 PHE A 115
PHE A 297
ALA A 298
THR A 302
 None
CPZ  A 501 (-4.3A)
CPZ  A 501 (-3.5A)
CPZ  A 501 ( 3.7A)
 0.61A 3t3zB-3tk3A:
53.9		 3t3zB-3tk3A:
49.58
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3T3Z_C_9PLC501_1
(CYTOCHROME P450 2E1)		 3tk3 CYTOCHROME P450 2B4
(Oryctolagus
cuniculus) 		4 / 5 PHE A 115
PHE A 297
ALA A 298
THR A 302
 None
CPZ  A 501 (-4.3A)
CPZ  A 501 (-3.5A)
CPZ  A 501 ( 3.7A)
 0.56A 3t3zC-3tk3A:
54.0		 3t3zC-3tk3A:
49.58
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3T3Z_D_9PLD501_1
(CYTOCHROME P450 2E1)		 3tk3 CYTOCHROME P450 2B4
(Oryctolagus
cuniculus) 		4 / 6 PHE A 115
PHE A 297
ALA A 298
THR A 302
 None
CPZ  A 501 (-4.3A)
CPZ  A 501 (-3.5A)
CPZ  A 501 ( 3.7A)
 0.60A 3t3zD-3tk3A:
53.9		 3t3zD-3tk3A:
49.58
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3TMZ_A_06XA503_1
(CYTOCHROME P450 2B4)		 3tk3 CYTOCHROME P450 2B4
(Oryctolagus
cuniculus) 		7 / 11 ILE A 101
ILE A 114
ILE A 209
ALA A 298
THR A 302
VAL A 367
PRO A 368
 CPZ  A 501 (-4.2A)
HEM  A 500 (-4.0A)
None
CPZ  A 501 (-3.5A)
CPZ  A 501 ( 3.7A)
HEM  A 500 ( 4.3A)
None
 0.94A 3tmzA-3tk3A:
56.8		 3tmzA-3tk3A:
99.79
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3TMZ_A_06XA503_1
(CYTOCHROME P450 2B4)		 3tk3 CYTOCHROME P450 2B4
(Oryctolagus
cuniculus) 		6 / 11 ILE A 101
ILE A 114
PHE A 115
ILE A 209
ALA A 298
THR A 302
 CPZ  A 501 (-4.2A)
HEM  A 500 (-4.0A)
None
None
CPZ  A 501 (-3.5A)
CPZ  A 501 ( 3.7A)
 1.12A 3tmzA-3tk3A:
56.8		 3tmzA-3tk3A:
99.79
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3TMZ_A_06XA503_1
(CYTOCHROME P450 2B4)		 3tk3 CYTOCHROME P450 2B4
(Oryctolagus
cuniculus) 		6 / 11 ILE A 101
ILE A 114
PHE A 206
ILE A 209
ALA A 298
THR A 302
 CPZ  A 501 (-4.2A)
HEM  A 500 (-4.0A)
None
None
CPZ  A 501 (-3.5A)
CPZ  A 501 ( 3.7A)
 1.16A 3tmzA-3tk3A:
56.8		 3tmzA-3tk3A:
99.79
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3TMZ_A_06XA503_1
(CYTOCHROME P450 2B4)		 3tk3 CYTOCHROME P450 2B4
(Oryctolagus
cuniculus) 		6 / 11 ILE A 114
PHE A 108
ILE A 209
ALA A 298
THR A 302
VAL A 367
 HEM  A 500 (-4.0A)
None
None
CPZ  A 501 (-3.5A)
CPZ  A 501 ( 3.7A)
HEM  A 500 ( 4.3A)
 1.16A 3tmzA-3tk3A:
56.8		 3tmzA-3tk3A:
99.79
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3TMZ_A_06XA503_1
(CYTOCHROME P450 2B4)		 3tk3 CYTOCHROME P450 2B4
(Oryctolagus
cuniculus) 		6 / 11 ILE A 114
PHE A 108
PHE A 206
ILE A 209
ALA A 298
THR A 302
 HEM  A 500 (-4.0A)
None
None
None
CPZ  A 501 (-3.5A)
CPZ  A 501 ( 3.7A)
 1.39A 3tmzA-3tk3A:
56.8		 3tmzA-3tk3A:
99.79
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3TMZ_A_06XA503_1
(CYTOCHROME P450 2B4)		 5e0e CYTOCHROME P450
FAMILY 2 SUBFAMILY B
(Neotoma
lepida) 		7 / 11 ILE A 101
PHE A 108
PHE A 206
ILE A 209
ALA A 298
GLU A 301
THR A 302
 CPZ  A 502 (-4.7A)
None
None
None
HEM  A 501 ( 3.1A)
None
CPZ  A 502 ( 4.0A)
 1.24A 3tmzA-5e0eA:
55.8		 3tmzA-5e0eA:
79.87
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3TMZ_A_06XA503_1
(CYTOCHROME P450 2B4)		 5e0e CYTOCHROME P450
FAMILY 2 SUBFAMILY B
(Neotoma
lepida) 		8 / 11 ILE A 101
PHE A 206
ILE A 209
ALA A 298
GLU A 301
THR A 302
VAL A 367
PRO A 368
 CPZ  A 502 (-4.7A)
None
None
HEM  A 501 ( 3.1A)
None
CPZ  A 502 ( 4.0A)
HEM  A 501 ( 4.4A)
None
 0.87A 3tmzA-5e0eA:
55.8		 3tmzA-5e0eA:
79.87
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3TMZ_A_06XA503_1
(CYTOCHROME P450 2B4)		 5e0e CYTOCHROME P450
FAMILY 2 SUBFAMILY B
(Neotoma
lepida) 		6 / 11 PHE A 115
ILE A 209
ALA A 298
GLU A 301
THR A 302
VAL A 367
 None
None
HEM  A 501 ( 3.1A)
None
CPZ  A 502 ( 4.0A)
HEM  A 501 ( 4.4A)
 0.88A 3tmzA-5e0eA:
55.8		 3tmzA-5e0eA:
79.87
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3TMZ_A_06XA504_1
(CYTOCHROME P450 2B4)		 3tk3 CYTOCHROME P450 2B4
(Oryctolagus
cuniculus) 		5 / 9 LEU A  70
ILE A 101
ILE A 209
GLN A 215
GLU A 387
 None
CPZ  A 501 (-4.2A)
None
None
None
 1.07A 3tmzA-3tk3A:
56.8		 3tmzA-3tk3A:
99.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FGL_D_CLQD303_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 3tk3 CYTOCHROME P450 2B4
(Oryctolagus
cuniculus) 		4 / 6 GLY A 478
GLY A 476
GLU A 301
ILE A 209
 None
None
CPZ  A 501 (-3.8A)
None
 0.97A 4fglD-3tk3A:
undetectable		 4fglD-3tk3A:
18.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4H1N_A_CGEA505_1
(CYTOCHROME P450 2B4)		 3tk3 CYTOCHROME P450 2B4
(Oryctolagus
cuniculus) 		8 / 11 ILE A 101
ILE A 114
ILE A 209
LEU A 238
ALA A 298
THR A 302
ILE A 363
VAL A 367
 CPZ  A 501 (-4.2A)
HEM  A 500 (-4.0A)
None
None
CPZ  A 501 (-3.5A)
CPZ  A 501 ( 3.7A)
HEM  A 500 ( 3.9A)
HEM  A 500 ( 4.3A)
 0.52A 4h1nA-3tk3A:
59.7		 4h1nA-3tk3A:
99.58
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4H1N_A_CGEA505_1
(CYTOCHROME P450 2B4)		 5e0e CYTOCHROME P450
FAMILY 2 SUBFAMILY B
(Neotoma
lepida) 		6 / 11 ILE A 101
LEU A 238
ALA A 298
THR A 302
ILE A 363
VAL A 367
 CPZ  A 502 (-4.7A)
None
HEM  A 501 ( 3.1A)
CPZ  A 502 ( 4.0A)
HEM  A 501 (-4.1A)
HEM  A 501 ( 4.4A)
 0.66A 4h1nA-5e0eA:
53.7		 4h1nA-5e0eA:
79.66
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4JLT_A_8PRA505_1
(CYTOCHROME P450 2B4)		 3tk3 CYTOCHROME P450 2B4
(Oryctolagus
cuniculus) 		5 / 8 ILE A 114
GLU A 218
ALA A 298
VAL A 367
PRO A 368
 HEM  A 500 (-4.0A)
None
CPZ  A 501 (-3.5A)
HEM  A 500 ( 4.3A)
None
 0.64A 4jltA-3tk3A:
60.7		 4jltA-3tk3A:
99.79
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4JLT_A_8PRA505_1
(CYTOCHROME P450 2B4)		 5e0e CYTOCHROME P450
FAMILY 2 SUBFAMILY B
(Neotoma
lepida) 		5 / 8 ILE A 101
GLU A 218
ALA A 298
VAL A 367
PRO A 368
 CPZ  A 502 (-4.7A)
None
HEM  A 501 ( 3.1A)
HEM  A 501 ( 4.4A)
None
 1.09A 4jltA-5e0eA:
54.7		 4jltA-5e0eA:
79.87