SIMILAR PATTERN OF AMINO ACIDS MAPPED TO 'CPS'


List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1A28_A_STRA1_1
(PROGESTERONE
RECEPTOR)		 5uc1 GLUCOCORTICOID
RECEPTOR
(Heterocephalus
glaber) 		7 / 12 LEU A 559
ASN A 560
LEU A 562
GLN A 566
MET A 597
ARG A 607
MET A 642
 486  A 801 (-4.7A)
486  A 801 (-4.2A)
486  A 801 ( 4.8A)
486  A 801 (-2.8A)
CPS  A 803 ( 3.9A)
486  A 801 (-3.5A)
486  A 801 ( 3.8A)
 0.76A 1a28A-5uc1A:
25.0		 1a28A-5uc1A:
56.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1A28_B_STRB2_1
(PROGESTERONE
RECEPTOR)		 5uc1 GLUCOCORTICOID
RECEPTOR
(Heterocephalus
glaber) 		7 / 12 LEU A 559
ASN A 560
LEU A 562
GLN A 566
MET A 597
ARG A 607
MET A 642
 486  A 801 (-4.7A)
486  A 801 (-4.2A)
486  A 801 ( 4.8A)
486  A 801 (-2.8A)
CPS  A 803 ( 3.9A)
486  A 801 (-3.5A)
486  A 801 ( 3.8A)
 0.79A 1a28B-5uc1A:
25.0		 1a28B-5uc1A:
56.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DSC_C_DVAC8_0
(ACTINOMYCIN D)		 5yid PLASMEPSIN II
(Plasmodium
falciparum) 		3 / 3 THR A 116
THR A 118
PRO A 115
 K95  A 401 ( 4.9A)
None
CPS  A 402 ( 4.9A)
 0.84A 1dscC-5yidA:
undetectable		 1dscC-5yidA:
undetectable
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1GS4_A_ZK5A1918_1
(ANDROGEN RECEPTOR)		 5uc1 GLUCOCORTICOID
RECEPTOR
(Heterocephalus
glaber) 		6 / 12 LEU A 559
ASN A 560
LEU A 562
GLY A 563
GLN A 566
MET A 597
 486  A 801 (-4.7A)
486  A 801 (-4.2A)
486  A 801 ( 4.8A)
486  A 801 (-3.7A)
486  A 801 (-2.8A)
CPS  A 803 ( 3.9A)
 0.86A 1gs4A-5uc1A:
23.3		 1gs4A-5uc1A:
51.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1M2Z_A_DEXA301_1
(GLUCOCORTICOID
RECEPTOR)		 5uc1 GLUCOCORTICOID
RECEPTOR
(Heterocephalus
glaber) 		6 / 12 ASN A 560
GLY A 563
GLN A 566
MET A 597
ARG A 607
MET A 642
 486  A 801 (-4.2A)
486  A 801 (-3.7A)
486  A 801 (-2.8A)
CPS  A 803 ( 3.9A)
486  A 801 (-3.5A)
486  A 801 ( 3.8A)
 0.67A 1m2zA-5uc1A:
26.2		 1m2zA-5uc1A:
95.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1M2Z_A_DEXA301_1
(GLUCOCORTICOID
RECEPTOR)		 5uc1 GLUCOCORTICOID
RECEPTOR
(Heterocephalus
glaber) 		6 / 12 GLY A 563
GLN A 566
TRP A 596
MET A 597
ARG A 607
MET A 642
 486  A 801 (-3.7A)
486  A 801 (-2.8A)
None
CPS  A 803 ( 3.9A)
486  A 801 (-3.5A)
486  A 801 ( 3.8A)
 0.78A 1m2zA-5uc1A:
26.2		 1m2zA-5uc1A:
95.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1M2Z_D_DEXD401_1
(GLUCOCORTICOID
RECEPTOR)		 5uc1 GLUCOCORTICOID
RECEPTOR
(Heterocephalus
glaber) 		7 / 12 MET A 556
ASN A 560
GLY A 563
GLN A 566
MET A 597
ARG A 607
MET A 642
 None
486  A 801 (-4.2A)
486  A 801 (-3.7A)
486  A 801 (-2.8A)
CPS  A 803 ( 3.9A)
486  A 801 (-3.5A)
486  A 801 ( 3.8A)
 0.79A 1m2zD-5uc1A:
26.1		 1m2zD-5uc1A:
95.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1NHZ_A_486A800_1
(GLUCOCORTICOID
RECEPTOR)		 5uc1 GLUCOCORTICOID
RECEPTOR
(Heterocephalus
glaber) 		5 / 12 VAL A 567
MET A 600
LEU A 604
ARG A 607
GLN A 641
 None
None
486  A 801 ( 3.8A)
486  A 801 (-3.5A)
CPS  A 803 (-3.5A)
 1.39A 1nhzA-5uc1A:
26.9		 1nhzA-5uc1A:
75.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1O76_B_CAMB1420_0
(CYTOCHROME P450-CAM)		 5xga OSMOLARITY SENSOR
PROTEIN ENVZ
(Escherichia
coli) 		4 / 8 TYR A  48
LEU A  55
VAL A 112
THR A 104
 CPS  A 202 (-3.4A)
CPS  A 201 ( 4.6A)
None
CPS  A 201 (-2.7A)
 1.01A 1o76B-5xgaA:
undetectable		 1o76B-5xgaA:
15.17
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1P93_A_DEXA1999_1
(GLUCOCORTICOID
RECEPTOR)		 5uc1 GLUCOCORTICOID
RECEPTOR
(Heterocephalus
glaber) 		8 / 12 LEU A 559
ASN A 560
LEU A 562
GLY A 563
GLN A 566
MET A 597
ARG A 607
MET A 642
 486  A 801 (-4.7A)
486  A 801 (-4.2A)
486  A 801 ( 4.8A)
486  A 801 (-3.7A)
486  A 801 (-2.8A)
CPS  A 803 ( 3.9A)
486  A 801 (-3.5A)
486  A 801 ( 3.8A)
 0.81A 1p93A-5uc1A:
25.4		 1p93A-5uc1A:
75.49
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1P93_A_DEXA1999_1
(GLUCOCORTICOID
RECEPTOR)		 5uc1 GLUCOCORTICOID
RECEPTOR
(Heterocephalus
glaber) 		7 / 12 LEU A 559
ASN A 560
LEU A 562
GLY A 563
GLN A 566
MET A 597
GLN A 638
 486  A 801 (-4.7A)
486  A 801 (-4.2A)
486  A 801 ( 4.8A)
486  A 801 (-3.7A)
486  A 801 (-2.8A)
CPS  A 803 ( 3.9A)
486  A 801 (-4.6A)
 0.96A 1p93A-5uc1A:
25.4		 1p93A-5uc1A:
75.49
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1P93_A_DEXA1999_1
(GLUCOCORTICOID
RECEPTOR)		 5uc1 GLUCOCORTICOID
RECEPTOR
(Heterocephalus
glaber) 		6 / 12 MET A 556
ASN A 560
GLY A 563
GLN A 566
MET A 597
GLN A 638
 None
486  A 801 (-4.2A)
486  A 801 (-3.7A)
486  A 801 (-2.8A)
CPS  A 803 ( 3.9A)
486  A 801 (-4.6A)
 1.05A 1p93A-5uc1A:
25.4		 1p93A-5uc1A:
75.49
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1P93_B_DEXB2999_1
(GLUCOCORTICOID
RECEPTOR)		 5uc1 GLUCOCORTICOID
RECEPTOR
(Heterocephalus
glaber) 		7 / 12 ASN A 560
GLY A 563
GLN A 566
MET A 597
LEU A 604
ARG A 607
MET A 642
 486  A 801 (-4.2A)
486  A 801 (-3.7A)
486  A 801 (-2.8A)
CPS  A 803 ( 3.9A)
486  A 801 ( 3.8A)
486  A 801 (-3.5A)
486  A 801 ( 3.8A)
 0.75A 1p93B-5uc1A:
25.1		 1p93B-5uc1A:
75.49
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1P93_C_DEXC3999_1
(GLUCOCORTICOID
RECEPTOR)		 5uc1 GLUCOCORTICOID
RECEPTOR
(Heterocephalus
glaber) 		6 / 12 ASN A 560
GLY A 563
GLN A 566
MET A 597
ARG A 607
GLN A 638
 486  A 801 (-4.2A)
486  A 801 (-3.7A)
486  A 801 (-2.8A)
CPS  A 803 ( 3.9A)
486  A 801 (-3.5A)
486  A 801 (-4.6A)
 1.00A 1p93C-5uc1A:
25.2		 1p93C-5uc1A:
75.49
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1P93_C_DEXC3999_1
(GLUCOCORTICOID
RECEPTOR)		 5uc1 GLUCOCORTICOID
RECEPTOR
(Heterocephalus
glaber) 		7 / 12 ASN A 560
GLY A 563
GLN A 566
MET A 597
LEU A 604
ARG A 607
MET A 642
 486  A 801 (-4.2A)
486  A 801 (-3.7A)
486  A 801 (-2.8A)
CPS  A 803 ( 3.9A)
486  A 801 ( 3.8A)
486  A 801 (-3.5A)
486  A 801 ( 3.8A)
 0.79A 1p93C-5uc1A:
25.2		 1p93C-5uc1A:
75.49
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1P93_D_DEXD4999_1
(GLUCOCORTICOID
RECEPTOR)		 5uc1 GLUCOCORTICOID
RECEPTOR
(Heterocephalus
glaber) 		7 / 12 ASN A 560
GLY A 563
GLN A 566
MET A 597
ARG A 607
PHE A 619
MET A 642
 486  A 801 (-4.2A)
486  A 801 (-3.7A)
486  A 801 (-2.8A)
CPS  A 803 ( 3.9A)
486  A 801 (-3.5A)
486  A 801 (-4.7A)
486  A 801 ( 3.8A)
 0.78A 1p93D-5uc1A:
25.0		 1p93D-5uc1A:
75.49
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1P93_D_DEXD4999_2
(GLUCOCORTICOID
RECEPTOR)		 5uc1 GLUCOCORTICOID
RECEPTOR
(Heterocephalus
glaber) 		4 / 5 TRP A 596
MET A 600
LEU A 604
GLN A 641
 None
None
486  A 801 ( 3.8A)
CPS  A 803 (-3.5A)
 1.17A 1p93D-5uc1A:
25.0		 1p93D-5uc1A:
75.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q97_B_ADNB486_1
(SR PROTEIN KINASE)		 5uc1 GLUCOCORTICOID
RECEPTOR
(Heterocephalus
glaber) 		4 / 4 VAL A 645
ALA A 601
LEU A 666
PHE A 602
 None
CPS  A 803 ( 3.9A)
None
None
 1.06A 1q97B-5uc1A:
undetectable		 1q97B-5uc1A:
11.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SQN_A_NDRA1001_0
(PROGESTERONE
RECEPTOR)		 5uc1 GLUCOCORTICOID
RECEPTOR
(Heterocephalus
glaber) 		7 / 12 LEU A 559
ASN A 560
LEU A 562
GLN A 566
MET A 597
MET A 600
MET A 642
 486  A 801 (-4.7A)
486  A 801 (-4.2A)
486  A 801 ( 4.8A)
486  A 801 (-2.8A)
CPS  A 803 ( 3.9A)
None
486  A 801 ( 3.8A)
 0.87A 1sqnA-5uc1A:
24.6		 1sqnA-5uc1A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SQN_B_NDRB2001_0
(PROGESTERONE
RECEPTOR)		 5uc1 GLUCOCORTICOID
RECEPTOR
(Heterocephalus
glaber) 		6 / 12 LEU A 559
ASN A 560
LEU A 562
GLN A 566
MET A 597
MET A 642
 486  A 801 (-4.7A)
486  A 801 (-4.2A)
486  A 801 ( 4.8A)
486  A 801 (-2.8A)
CPS  A 803 ( 3.9A)
486  A 801 ( 3.8A)
 0.78A 1sqnB-5uc1A:
24.8		 1sqnB-5uc1A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SQN_B_NDRB2001_0
(PROGESTERONE
RECEPTOR)		 5uc1 GLUCOCORTICOID
RECEPTOR
(Heterocephalus
glaber) 		6 / 12 LEU A 559
LEU A 562
GLN A 566
MET A 597
MET A 600
MET A 642
 486  A 801 (-4.7A)
486  A 801 ( 4.8A)
486  A 801 (-2.8A)
CPS  A 803 ( 3.9A)
None
486  A 801 ( 3.8A)
 0.83A 1sqnB-5uc1A:
24.8		 1sqnB-5uc1A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UYU_B_CAMB1416_0
(CYTOCHROME P450-CAM)		 5xga OSMOLARITY SENSOR
PROTEIN ENVZ
(Escherichia
coli) 		4 / 8 TYR A  48
LEU A  55
VAL A 112
THR A 104
 CPS  A 202 (-3.4A)
CPS  A 201 ( 4.6A)
None
CPS  A 201 (-2.7A)
 1.17A 1uyuB-5xgaA:
undetectable		 1uyuB-5xgaA:
15.17
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1YA3_A_STRA1001_1
(MINERALOCORTICOID
RECEPTOR)		 5uc1 GLUCOCORTICOID
RECEPTOR
(Heterocephalus
glaber) 		7 / 12 ASN A 560
LEU A 562
GLN A 566
MET A 597
LEU A 604
ARG A 607
MET A 642
 486  A 801 (-4.2A)
486  A 801 ( 4.8A)
486  A 801 (-2.8A)
CPS  A 803 ( 3.9A)
486  A 801 ( 3.8A)
486  A 801 (-3.5A)
486  A 801 ( 3.8A)
 0.77A 1ya3A-5uc1A:
22.1		 1ya3A-5uc1A:
56.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1YA3_B_STRB2001_1
(MINERALOCORTICOID
RECEPTOR)		 5uc1 GLUCOCORTICOID
RECEPTOR
(Heterocephalus
glaber) 		5 / 12 ASN A 560
GLN A 566
MET A 597
LEU A 604
ARG A 607
 486  A 801 (-4.2A)
486  A 801 (-2.8A)
CPS  A 803 ( 3.9A)
486  A 801 ( 3.8A)
486  A 801 (-3.5A)
 0.76A 1ya3B-5uc1A:
21.7		 1ya3B-5uc1A:
56.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1YA3_C_STRC3001_1
(MINERALOCORTICOID
RECEPTOR)		 5uc1 GLUCOCORTICOID
RECEPTOR
(Heterocephalus
glaber) 		6 / 12 LEU A 559
ASN A 560
LEU A 562
GLN A 566
MET A 597
ARG A 607
 486  A 801 (-4.7A)
486  A 801 (-4.2A)
486  A 801 ( 4.8A)
486  A 801 (-2.8A)
CPS  A 803 ( 3.9A)
486  A 801 (-3.5A)
 0.76A 1ya3C-5uc1A:
21.7		 1ya3C-5uc1A:
56.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z95_A_198A501_1
(ANDROGEN RECEPTOR)		 5uc1 GLUCOCORTICOID
RECEPTOR
(Heterocephalus
glaber) 		5 / 12 GLY A 563
GLN A 566
MET A 597
MET A 600
ARG A 607
 486  A 801 (-3.7A)
486  A 801 (-2.8A)
CPS  A 803 ( 3.9A)
None
486  A 801 (-3.5A)
 0.71A 1z95A-5uc1A:
22.6		 1z95A-5uc1A:
29.63
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ZUC_B_T98B202_1
(PROGESTERONE
RECEPTOR)		 5uc1 GLUCOCORTICOID
RECEPTOR
(Heterocephalus
glaber) 		6 / 12 ASN A 560
LEU A 562
GLN A 566
MET A 597
LEU A 604
ARG A 607
 486  A 801 (-4.2A)
486  A 801 ( 4.8A)
486  A 801 (-2.8A)
CPS  A 803 ( 3.9A)
486  A 801 ( 3.8A)
486  A 801 (-3.5A)
 0.86A 1zucB-5uc1A:
24.6		 1zucB-5uc1A:
58.75
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1ZUC_B_T98B202_1
(PROGESTERONE
RECEPTOR)		 5uc1 GLUCOCORTICOID
RECEPTOR
(Heterocephalus
glaber) 		6 / 12 LEU A 562
GLN A 566
MET A 597
MET A 600
LEU A 604
ARG A 607
 486  A 801 ( 4.8A)
486  A 801 (-2.8A)
CPS  A 803 ( 3.9A)
None
486  A 801 ( 3.8A)
486  A 801 (-3.5A)
 0.81A 1zucB-5uc1A:
24.6		 1zucB-5uc1A:
58.75
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2AA5_A_STRA301_1
(MINERALOCORTICOID
RECEPTOR)		 5uc1 GLUCOCORTICOID
RECEPTOR
(Heterocephalus
glaber) 		7 / 12 ASN A 560
LEU A 562
GLN A 566
MET A 597
LEU A 604
ARG A 607
MET A 642
 486  A 801 (-4.2A)
486  A 801 ( 4.8A)
486  A 801 (-2.8A)
CPS  A 803 ( 3.9A)
486  A 801 ( 3.8A)
486  A 801 (-3.5A)
486  A 801 ( 3.8A)
 0.83A 2aa5A-5uc1A:
22.8		 2aa5A-5uc1A:
53.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2AA5_B_STRB302_1
(MINERALOCORTICOID
RECEPTOR)		 5uc1 GLUCOCORTICOID
RECEPTOR
(Heterocephalus
glaber) 		6 / 12 ASN A 560
LEU A 562
GLN A 566
MET A 597
LEU A 604
ARG A 607
 486  A 801 (-4.2A)
486  A 801 ( 4.8A)
486  A 801 (-2.8A)
CPS  A 803 ( 3.9A)
486  A 801 ( 3.8A)
486  A 801 (-3.5A)
 0.74A 2aa5B-5uc1A:
23.0		 2aa5B-5uc1A:
53.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2AA6_A_STRA401_1
(MINERALOCORTICOID
RECEPTOR)		 5uc1 GLUCOCORTICOID
RECEPTOR
(Heterocephalus
glaber) 		8 / 12 LEU A 559
ASN A 560
LEU A 562
GLN A 566
MET A 597
LEU A 604
ARG A 607
MET A 642
 486  A 801 (-4.7A)
486  A 801 (-4.2A)
486  A 801 ( 4.8A)
486  A 801 (-2.8A)
CPS  A 803 ( 3.9A)
486  A 801 ( 3.8A)
486  A 801 (-3.5A)
486  A 801 ( 3.8A)
 0.85A 2aa6A-5uc1A:
23.2		 2aa6A-5uc1A:
53.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2AA6_B_STRB402_1
(MINERALOCORTICOID
RECEPTOR)		 5uc1 GLUCOCORTICOID
RECEPTOR
(Heterocephalus
glaber) 		7 / 12 ASN A 560
LEU A 562
GLN A 566
MET A 597
LEU A 604
ARG A 607
MET A 642
 486  A 801 (-4.2A)
486  A 801 ( 4.8A)
486  A 801 (-2.8A)
CPS  A 803 ( 3.9A)
486  A 801 ( 3.8A)
486  A 801 (-3.5A)
486  A 801 ( 3.8A)
 0.84A 2aa6B-5uc1A:
23.1		 2aa6B-5uc1A:
53.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2AB2_A_SNLA502_1
(MINERALOCORTICOID
RECEPTOR)		 5uc1 GLUCOCORTICOID
RECEPTOR
(Heterocephalus
glaber) 		6 / 12 ASN A 560
GLN A 566
MET A 597
ARG A 607
PHE A 619
MET A 642
 486  A 801 (-4.2A)
486  A 801 (-2.8A)
CPS  A 803 ( 3.9A)
486  A 801 (-3.5A)
486  A 801 (-4.7A)
486  A 801 ( 3.8A)
 0.82A 2ab2A-5uc1A:
23.2		 2ab2A-5uc1A:
53.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2AB2_B_SNLB503_1
(MINERALOCORTICOID
RECEPTOR)		 5uc1 GLUCOCORTICOID
RECEPTOR
(Heterocephalus
glaber) 		6 / 12 ASN A 560
GLN A 566
MET A 597
ARG A 607
PHE A 619
MET A 642
 486  A 801 (-4.2A)
486  A 801 (-2.8A)
CPS  A 803 ( 3.9A)
486  A 801 (-3.5A)
486  A 801 (-4.7A)
486  A 801 ( 3.8A)
 0.85A 2ab2B-5uc1A:
23.2		 2ab2B-5uc1A:
53.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2AM9_A_TESA1000_1
(ANDROGEN RECEPTOR)		 5uc1 GLUCOCORTICOID
RECEPTOR
(Heterocephalus
glaber) 		5 / 12 ASN A 560
LEU A 562
MET A 597
MET A 600
ARG A 607
 486  A 801 (-4.2A)
486  A 801 ( 4.8A)
CPS  A 803 ( 3.9A)
None
486  A 801 (-3.5A)
 0.75A 2am9A-5uc1A:
23.5		 2am9A-5uc1A:
46.67
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2AM9_A_TESA1000_1
(ANDROGEN RECEPTOR)		 5uc1 GLUCOCORTICOID
RECEPTOR
(Heterocephalus
glaber) 		5 / 12 GLN A 566
TRP A 596
MET A 597
MET A 600
ARG A 607
 486  A 801 (-2.8A)
None
CPS  A 803 ( 3.9A)
None
486  A 801 (-3.5A)
 1.01A 2am9A-5uc1A:
23.5		 2am9A-5uc1A:
46.67
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2AM9_A_TESA1000_1
(ANDROGEN RECEPTOR)		 5uc1 GLUCOCORTICOID
RECEPTOR
(Heterocephalus
glaber) 		5 / 12 LEU A 562
GLN A 566
MET A 597
MET A 600
ARG A 607
 486  A 801 ( 4.8A)
486  A 801 (-2.8A)
CPS  A 803 ( 3.9A)
None
486  A 801 (-3.5A)
 1.11A 2am9A-5uc1A:
23.5		 2am9A-5uc1A:
46.67
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2OAX_A_SNLA1001_1
(MINERALOCORTICOID
RECEPTOR)		 5uc1 GLUCOCORTICOID
RECEPTOR
(Heterocephalus
glaber) 		6 / 12 ASN A 560
LEU A 562
GLN A 566
MET A 597
LEU A 604
ARG A 607
 486  A 801 (-4.2A)
486  A 801 ( 4.8A)
486  A 801 (-2.8A)
CPS  A 803 ( 3.9A)
486  A 801 ( 3.8A)
486  A 801 (-3.5A)
 0.76A 2oaxA-5uc1A:
21.8		 2oaxA-5uc1A:
57.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2OAX_B_SNLB2001_1
(MINERALOCORTICOID
RECEPTOR)		 5uc1 GLUCOCORTICOID
RECEPTOR
(Heterocephalus
glaber) 		6 / 12 ASN A 560
LEU A 562
GLN A 566
MET A 597
LEU A 604
ARG A 607
 486  A 801 (-4.2A)
486  A 801 ( 4.8A)
486  A 801 (-2.8A)
CPS  A 803 ( 3.9A)
486  A 801 ( 3.8A)
486  A 801 (-3.5A)
 0.61A 2oaxB-5uc1A:
21.8		 2oaxB-5uc1A:
57.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2OAX_C_SNLC3001_1
(MINERALOCORTICOID
RECEPTOR)		 5uc1 GLUCOCORTICOID
RECEPTOR
(Heterocephalus
glaber) 		5 / 12 ASN A 560
GLN A 566
MET A 597
LEU A 604
ARG A 607
 486  A 801 (-4.2A)
486  A 801 (-2.8A)
CPS  A 803 ( 3.9A)
486  A 801 ( 3.8A)
486  A 801 (-3.5A)
 0.67A 2oaxC-5uc1A:
21.3		 2oaxC-5uc1A:
57.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2OAX_C_SNLC3001_1
(MINERALOCORTICOID
RECEPTOR)		 5uc1 GLUCOCORTICOID
RECEPTOR
(Heterocephalus
glaber) 		5 / 12 GLN A 566
TRP A 596
MET A 597
LEU A 604
ARG A 607
 486  A 801 (-2.8A)
None
CPS  A 803 ( 3.9A)
486  A 801 ( 3.8A)
486  A 801 (-3.5A)
 0.59A 2oaxC-5uc1A:
21.3		 2oaxC-5uc1A:
57.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2OAX_D_SNLD4001_1
(MINERALOCORTICOID
RECEPTOR)		 5uc1 GLUCOCORTICOID
RECEPTOR
(Heterocephalus
glaber) 		6 / 12 ASN A 560
LEU A 562
GLN A 566
MET A 597
LEU A 604
ARG A 607
 486  A 801 (-4.2A)
486  A 801 ( 4.8A)
486  A 801 (-2.8A)
CPS  A 803 ( 3.9A)
486  A 801 ( 3.8A)
486  A 801 (-3.5A)
 0.70A 2oaxD-5uc1A:
22.2		 2oaxD-5uc1A:
57.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2OAX_D_SNLD4001_1
(MINERALOCORTICOID
RECEPTOR)		 5uc1 GLUCOCORTICOID
RECEPTOR
(Heterocephalus
glaber) 		6 / 12 LEU A 562
GLN A 566
TRP A 596
MET A 597
LEU A 604
ARG A 607
 486  A 801 ( 4.8A)
486  A 801 (-2.8A)
None
CPS  A 803 ( 3.9A)
486  A 801 ( 3.8A)
486  A 801 (-3.5A)
 0.70A 2oaxD-5uc1A:
22.2		 2oaxD-5uc1A:
57.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2OAX_E_SNLE5001_1
(MINERALOCORTICOID
RECEPTOR)		 5uc1 GLUCOCORTICOID
RECEPTOR
(Heterocephalus
glaber) 		6 / 12 ASN A 560
LEU A 562
GLN A 566
MET A 597
LEU A 604
ARG A 607
 486  A 801 (-4.2A)
486  A 801 ( 4.8A)
486  A 801 (-2.8A)
CPS  A 803 ( 3.9A)
486  A 801 ( 3.8A)
486  A 801 (-3.5A)
 0.60A 2oaxE-5uc1A:
22.0		 2oaxE-5uc1A:
57.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2OAX_F_SNLF6001_1
(MINERALOCORTICOID
RECEPTOR)		 5uc1 GLUCOCORTICOID
RECEPTOR
(Heterocephalus
glaber) 		6 / 12 ASN A 560
LEU A 562
GLN A 566
MET A 597
LEU A 604
ARG A 607
 486  A 801 (-4.2A)
486  A 801 ( 4.8A)
486  A 801 (-2.8A)
CPS  A 803 ( 3.9A)
486  A 801 ( 3.8A)
486  A 801 (-3.5A)
 0.72A 2oaxF-5uc1A:
22.5		 2oaxF-5uc1A:
57.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2OAX_F_SNLF6001_1
(MINERALOCORTICOID
RECEPTOR)		 5uc1 GLUCOCORTICOID
RECEPTOR
(Heterocephalus
glaber) 		6 / 12 LEU A 562
GLN A 566
TRP A 596
MET A 597
LEU A 604
ARG A 607
 486  A 801 ( 4.8A)
486  A 801 (-2.8A)
None
CPS  A 803 ( 3.9A)
486  A 801 ( 3.8A)
486  A 801 (-3.5A)
 0.64A 2oaxF-5uc1A:
22.5		 2oaxF-5uc1A:
57.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2Q7I_A_TESA205_1
(ANDROGEN RECEPTOR)		 5uc1 GLUCOCORTICOID
RECEPTOR
(Heterocephalus
glaber) 		7 / 12 LEU A 559
ASN A 560
LEU A 562
GLN A 566
MET A 597
MET A 600
ARG A 607
 486  A 801 (-4.7A)
486  A 801 (-4.2A)
486  A 801 ( 4.8A)
486  A 801 (-2.8A)
CPS  A 803 ( 3.9A)
None
486  A 801 (-3.5A)
 0.85A 2q7iA-5uc1A:
22.8		 2q7iA-5uc1A:
48.75
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2Q7J_A_TESA203_1
(ANDROGEN RECEPTOR)		 5uc1 GLUCOCORTICOID
RECEPTOR
(Heterocephalus
glaber) 		6 / 12 ASN A 560
LEU A 562
GLN A 566
MET A 597
MET A 600
ARG A 607
 486  A 801 (-4.2A)
486  A 801 ( 4.8A)
486  A 801 (-2.8A)
CPS  A 803 ( 3.9A)
None
486  A 801 (-3.5A)
 0.77A 2q7jA-5uc1A:
23.2		 2q7jA-5uc1A:
48.75
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2Q7J_A_TESA203_1
(ANDROGEN RECEPTOR)		 5uc1 GLUCOCORTICOID
RECEPTOR
(Heterocephalus
glaber) 		5 / 12 GLN A 566
TRP A 596
MET A 597
MET A 600
ARG A 607
 486  A 801 (-2.8A)
None
CPS  A 803 ( 3.9A)
None
486  A 801 (-3.5A)
 0.69A 2q7jA-5uc1A:
23.2		 2q7jA-5uc1A:
48.75
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2Q7K_A_TESA304_1
(ANDROGEN RECEPTOR)		 5uc1 GLUCOCORTICOID
RECEPTOR
(Heterocephalus
glaber) 		5 / 12 LEU A 559
ASN A 560
GLN A 566
MET A 597
ARG A 607
 486  A 801 (-4.7A)
486  A 801 (-4.2A)
486  A 801 (-2.8A)
CPS  A 803 ( 3.9A)
486  A 801 (-3.5A)
 0.86A 2q7kA-5uc1A:
23.1		 2q7kA-5uc1A:
48.75
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2Q7L_A_TESA155_1
(ANDROGEN RECEPTOR)		 5uc1 GLUCOCORTICOID
RECEPTOR
(Heterocephalus
glaber) 		6 / 12 LEU A 559
ASN A 560
GLY A 563
GLN A 566
MET A 597
ARG A 607
 486  A 801 (-4.7A)
486  A 801 (-4.2A)
486  A 801 (-3.7A)
486  A 801 (-2.8A)
CPS  A 803 ( 3.9A)
486  A 801 (-3.5A)
 0.82A 2q7lA-5uc1A:
23.3		 2q7lA-5uc1A:
48.75
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2W8Y_A_486A1000_1
(PROGESTERONE
RECEPTOR)		 5uc1 GLUCOCORTICOID
RECEPTOR
(Heterocephalus
glaber) 		7 / 12 LEU A 562
GLY A 563
GLN A 566
TRP A 596
MET A 597
MET A 600
ARG A 607
 486  A 801 ( 4.8A)
486  A 801 (-3.7A)
486  A 801 (-2.8A)
None
CPS  A 803 ( 3.9A)
None
486  A 801 (-3.5A)
 0.75A 2w8yA-5uc1A:
25.1		 2w8yA-5uc1A:
56.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W8Y_B_NDRB1000_0
(PROGESTERONE
RECEPTOR)		 5uc1 GLUCOCORTICOID
RECEPTOR
(Heterocephalus
glaber) 		8 / 12 LEU A 559
ASN A 560
LEU A 562
GLN A 566
MET A 597
MET A 600
ARG A 607
MET A 642
 486  A 801 (-4.7A)
486  A 801 (-4.2A)
486  A 801 ( 4.8A)
486  A 801 (-2.8A)
CPS  A 803 ( 3.9A)
None
486  A 801 (-3.5A)
486  A 801 ( 3.8A)
 0.77A 2w8yB-5uc1A:
25.1		 2w8yB-5uc1A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y05_A_RALA801_1
(PROSTAGLANDIN
REDUCTASE 1)		 5xga OSMOLARITY SENSOR
PROTEIN ENVZ
(Escherichia
coli) 		4 / 8 TYR A  48
ARG A 113
VAL A  21
VAL A 112
 CPS  A 202 (-3.4A)
None
None
None
 1.12A 2y05A-5xgaA:
undetectable
2y05B-5xgaA:
undetectable		 2y05A-5xgaA:
17.53
2y05B-5xgaA:
17.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YA7_A_ZMRA1776_2
(NEURAMINIDASE A)		 1hv5 STROMELYSIN 3
(Mus
musculus) 		4 / 6 ARG A 191
ASP A 158
ILE A 159
LEU A 138
 None
CPS  A5006 ( 4.9A)
None
None
 0.96A 2ya7A-1hv5A:
0.0		 2ya7A-1hv5A:
15.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YA7_B_ZMRB1776_2
(NEURAMINIDASE A)		 1hv5 STROMELYSIN 3
(Mus
musculus) 		4 / 6 ARG A 191
ASP A 158
ILE A 159
LEU A 138
 None
CPS  A5006 ( 4.9A)
None
None
 0.94A 2ya7B-1hv5A:
0.0		 2ya7B-1hv5A:
15.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YA7_C_ZMRC1776_2
(NEURAMINIDASE A)		 1hv5 STROMELYSIN 3
(Mus
musculus) 		4 / 6 ARG A 191
ASP A 158
ILE A 159
TYR A 261
 None
CPS  A5006 ( 4.9A)
None
None
 1.23A 2ya7C-1hv5A:
undetectable		 2ya7C-1hv5A:
15.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YA7_D_ZMRD1776_2
(NEURAMINIDASE A)		 1hv5 STROMELYSIN 3
(Mus
musculus) 		4 / 6 ARG A 191
ASP A 158
ILE A 159
LEU A 138
 None
CPS  A5006 ( 4.9A)
None
None
 0.94A 2ya7D-1hv5A:
0.0		 2ya7D-1hv5A:
15.26
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2YHD_A_TESA1920_1
(ANDROGEN RECEPTOR)		 5uc1 GLUCOCORTICOID
RECEPTOR
(Heterocephalus
glaber) 		6 / 12 ASN A 560
GLY A 563
GLN A 566
MET A 597
MET A 600
ARG A 607
 486  A 801 (-4.2A)
486  A 801 (-3.7A)
486  A 801 (-2.8A)
CPS  A 803 ( 3.9A)
None
486  A 801 (-3.5A)
 0.61A 2yhdA-5uc1A:
23.1		 2yhdA-5uc1A:
51.90
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2YLO_A_TESA1920_1
(ANDROGEN RECEPTOR)		 5uc1 GLUCOCORTICOID
RECEPTOR
(Heterocephalus
glaber) 		5 / 12 LEU A 559
ASN A 560
MET A 597
MET A 600
ARG A 607
 486  A 801 (-4.7A)
486  A 801 (-4.2A)
CPS  A 803 ( 3.9A)
None
486  A 801 (-3.5A)
 0.82A 2yloA-5uc1A:
23.1		 2yloA-5uc1A:
50.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2YLP_A_TESA1921_1
(ANDROGEN RECEPTOR)		 5uc1 GLUCOCORTICOID
RECEPTOR
(Heterocephalus
glaber) 		5 / 11 ASN A 560
GLN A 566
MET A 597
MET A 600
ARG A 607
 486  A 801 (-4.2A)
486  A 801 (-2.8A)
CPS  A 803 ( 3.9A)
None
486  A 801 (-3.5A)
 0.66A 2ylpA-5uc1A:
23.3		 2ylpA-5uc1A:
50.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2YLQ_A_TESA1921_1
(ANDROGEN RECEPTOR)		 5uc1 GLUCOCORTICOID
RECEPTOR
(Heterocephalus
glaber) 		5 / 11 ASN A 560
GLN A 566
MET A 597
MET A 600
ARG A 607
 486  A 801 (-4.2A)
486  A 801 (-2.8A)
CPS  A 803 ( 3.9A)
None
486  A 801 (-3.5A)
 0.65A 2ylqA-5uc1A:
23.3		 2ylqA-5uc1A:
50.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3CLD_A_GW6A1_1
(GLUCOCORTICOID
RECEPTOR)		 5uc1 GLUCOCORTICOID
RECEPTOR
(Heterocephalus
glaber) 		8 / 12 MET A 556
ASN A 560
GLY A 563
GLN A 566
MET A 597
LEU A 604
ARG A 607
CYH A 639
 None
486  A 801 (-4.2A)
486  A 801 (-3.7A)
486  A 801 (-2.8A)
CPS  A 803 ( 3.9A)
486  A 801 ( 3.8A)
486  A 801 (-3.5A)
486  A 801 ( 3.9A)
 0.75A 3cldA-5uc1A:
26.0		 3cldA-5uc1A:
95.06
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3CLD_A_GW6A1_2
(GLUCOCORTICOID
RECEPTOR)		 5uc1 GLUCOCORTICOID
RECEPTOR
(Heterocephalus
glaber) 		6 / 9 LEU A 559
LEU A 562
MET A 600
ALA A 601
MET A 635
MET A 642
 486  A 801 (-4.7A)
486  A 801 ( 4.8A)
None
CPS  A 803 ( 3.9A)
486  A 801 ( 4.7A)
486  A 801 ( 3.8A)
 0.83A 3cldA-5uc1A:
26.1		 3cldA-5uc1A:
95.06
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3CLD_A_GW6A1_2
(GLUCOCORTICOID
RECEPTOR)		 5uc1 GLUCOCORTICOID
RECEPTOR
(Heterocephalus
glaber) 		6 / 9 LEU A 562
TRP A 596
MET A 600
ALA A 601
MET A 635
MET A 642
 486  A 801 ( 4.8A)
None
None
CPS  A 803 ( 3.9A)
486  A 801 ( 4.7A)
486  A 801 ( 3.8A)
 0.88A 3cldA-5uc1A:
26.1		 3cldA-5uc1A:
95.06
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3CLD_B_GW6B2_1
(GLUCOCORTICOID
RECEPTOR)		 5uc1 GLUCOCORTICOID
RECEPTOR
(Heterocephalus
glaber) 		8 / 12 MET A 556
ASN A 560
GLY A 563
GLN A 566
MET A 597
ARG A 607
MET A 635
CYH A 639
 None
486  A 801 (-4.2A)
486  A 801 (-3.7A)
486  A 801 (-2.8A)
CPS  A 803 ( 3.9A)
486  A 801 (-3.5A)
486  A 801 ( 4.7A)
486  A 801 ( 3.9A)
 0.77A 3cldB-5uc1A:
26.0		 3cldB-5uc1A:
95.06
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3CLD_B_GW6B2_2
(GLUCOCORTICOID
RECEPTOR)		 5uc1 GLUCOCORTICOID
RECEPTOR
(Heterocephalus
glaber) 		4 / 8 LEU A 559
ALA A 601
LEU A 604
MET A 642
 486  A 801 (-4.7A)
CPS  A 803 ( 3.9A)
486  A 801 ( 3.8A)
486  A 801 ( 3.8A)
 0.68A 3cldB-5uc1A:
26.0		 3cldB-5uc1A:
95.06
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3CLD_B_GW6B2_2
(GLUCOCORTICOID
RECEPTOR)		 5uc1 GLUCOCORTICOID
RECEPTOR
(Heterocephalus
glaber) 		4 / 8 MET A 600
ALA A 601
LEU A 604
MET A 642
 None
CPS  A 803 ( 3.9A)
486  A 801 ( 3.8A)
486  A 801 ( 3.8A)
 0.70A 3cldB-5uc1A:
26.0		 3cldB-5uc1A:
95.06
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3D90_A_NOGA1001_1
(PROGESTERONE
RECEPTOR)		 5uc1 GLUCOCORTICOID
RECEPTOR
(Heterocephalus
glaber) 		8 / 12 LEU A 559
ASN A 560
LEU A 562
GLN A 566
MET A 597
MET A 600
ARG A 607
MET A 642
 486  A 801 (-4.7A)
486  A 801 (-4.2A)
486  A 801 ( 4.8A)
486  A 801 (-2.8A)
CPS  A 803 ( 3.9A)
None
486  A 801 (-3.5A)
486  A 801 ( 3.8A)
 0.82A 3d90A-5uc1A:
24.6		 3d90A-5uc1A:
58.75
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3D90_B_NOGB2001_1
(PROGESTERONE
RECEPTOR)		 5uc1 GLUCOCORTICOID
RECEPTOR
(Heterocephalus
glaber) 		8 / 12 LEU A 559
ASN A 560
LEU A 562
GLN A 566
MET A 597
LEU A 604
ARG A 607
MET A 642
 486  A 801 (-4.7A)
486  A 801 (-4.2A)
486  A 801 ( 4.8A)
486  A 801 (-2.8A)
CPS  A 803 ( 3.9A)
486  A 801 ( 3.8A)
486  A 801 (-3.5A)
486  A 801 ( 3.8A)
 0.77A 3d90B-5uc1A:
24.4		 3d90B-5uc1A:
58.75
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3GAN_A_SVRA158_1
(UNCHARACTERIZED
PROTEIN AT3G22680)		 1vk5 EXPRESSED PROTEIN
(Arabidopsis
thaliana) 		8 / 11 ARG A  41
TYR A  48
GLN A  51
VAL A  52
PRO A  53
PRO A  81
TRP A 140
ILE A 150
 CPS  A 200 ( 4.6A)
CPS  A 200 (-4.2A)
None
None
None
EDO  A 401 (-4.1A)
None
CPS  A 200 (-4.2A)
 0.95A 3ganA-1vk5A:
20.4		 3ganA-1vk5A:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3GAN_A_SVRA158_1
(UNCHARACTERIZED
PROTEIN AT3G22680)		 1vk5 EXPRESSED PROTEIN
(Arabidopsis
thaliana) 		6 / 11 GLN A  51
PRO A  81
TRP A 140
TYR A 146
ILE A 150
ILE A 153
 None
EDO  A 401 (-4.1A)
None
None
CPS  A 200 (-4.2A)
EDO  A 401 (-4.4A)
 0.94A 3ganA-1vk5A:
20.4		 3ganA-1vk5A:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3GAN_A_SVRA158_1
(UNCHARACTERIZED
PROTEIN AT3G22680)		 1vk5 EXPRESSED PROTEIN
(Arabidopsis
thaliana) 		8 / 11 TYR A  48
GLN A  51
VAL A  52
PRO A  53
PRO A  81
TRP A 140
TYR A 146
ILE A 150
 CPS  A 200 (-4.2A)
None
None
None
EDO  A 401 (-4.1A)
None
None
CPS  A 200 (-4.2A)
 0.67A 3ganA-1vk5A:
20.4		 3ganA-1vk5A:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3GN8_A_DEXA247_1
(GLUCOCORTICOID
RECEPTOR 2)		 5uc1 GLUCOCORTICOID
RECEPTOR
(Heterocephalus
glaber) 		6 / 12 GLY A 563
GLN A 566
TRP A 596
MET A 597
ARG A 607
MET A 642
 486  A 801 (-3.7A)
486  A 801 (-2.8A)
None
CPS  A 803 ( 3.9A)
486  A 801 (-3.5A)
486  A 801 ( 3.8A)
 0.72A 3gn8A-5uc1A:
25.7		 3gn8A-5uc1A:
76.92
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3GN8_A_DEXA247_1
(GLUCOCORTICOID
RECEPTOR 2)		 5uc1 GLUCOCORTICOID
RECEPTOR
(Heterocephalus
glaber) 		6 / 12 LEU A 559
GLY A 563
GLN A 566
MET A 597
ARG A 607
MET A 642
 486  A 801 (-4.7A)
486  A 801 (-3.7A)
486  A 801 (-2.8A)
CPS  A 803 ( 3.9A)
486  A 801 (-3.5A)
486  A 801 ( 3.8A)
 0.80A 3gn8A-5uc1A:
25.7		 3gn8A-5uc1A:
76.92
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3GN8_B_DEXB247_1
(GLUCOCORTICOID
RECEPTOR 2)		 5uc1 GLUCOCORTICOID
RECEPTOR
(Heterocephalus
glaber) 		6 / 12 GLY A 563
GLN A 566
TRP A 596
MET A 597
ARG A 607
MET A 642
 486  A 801 (-3.7A)
486  A 801 (-2.8A)
None
CPS  A 803 ( 3.9A)
486  A 801 (-3.5A)
486  A 801 ( 3.8A)
 0.74A 3gn8B-5uc1A:
25.6		 3gn8B-5uc1A:
76.92
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3GN8_B_DEXB247_1
(GLUCOCORTICOID
RECEPTOR 2)		 5uc1 GLUCOCORTICOID
RECEPTOR
(Heterocephalus
glaber) 		7 / 12 LEU A 559
ASN A 560
GLY A 563
GLN A 566
MET A 597
ARG A 607
MET A 642
 486  A 801 (-4.7A)
486  A 801 (-4.2A)
486  A 801 (-3.7A)
486  A 801 (-2.8A)
CPS  A 803 ( 3.9A)
486  A 801 (-3.5A)
486  A 801 ( 3.8A)
 0.92A 3gn8B-5uc1A:
25.6		 3gn8B-5uc1A:
76.92
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3H52_A_486A3_1
(GLUCOCORTICOID
RECEPTOR)		 5uc1 GLUCOCORTICOID
RECEPTOR
(Heterocephalus
glaber) 		8 / 12 LEU A 559
ASN A 560
GLY A 563
GLN A 566
VAL A 567
MET A 597
ARG A 607
MET A 642
 486  A 801 (-4.7A)
486  A 801 (-4.2A)
486  A 801 (-3.7A)
486  A 801 (-2.8A)
None
CPS  A 803 ( 3.9A)
486  A 801 (-3.5A)
486  A 801 ( 3.8A)
 0.55A 3h52A-5uc1A:
20.8		 3h52A-5uc1A:
87.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3H52_C_486C4_1
(GLUCOCORTICOID
RECEPTOR)		 5uc1 GLUCOCORTICOID
RECEPTOR
(Heterocephalus
glaber) 		8 / 12 GLY A 563
GLN A 566
VAL A 567
MET A 597
LEU A 604
ARG A 607
PHE A 619
MET A 642
 486  A 801 (-3.7A)
486  A 801 (-2.8A)
None
CPS  A 803 ( 3.9A)
486  A 801 ( 3.8A)
486  A 801 (-3.5A)
486  A 801 (-4.7A)
486  A 801 ( 3.8A)
 0.65A 3h52C-5uc1A:
20.2		 3h52C-5uc1A:
87.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3H52_C_486C4_1
(GLUCOCORTICOID
RECEPTOR)		 5uc1 GLUCOCORTICOID
RECEPTOR
(Heterocephalus
glaber) 		8 / 12 GLY A 563
GLN A 566
VAL A 567
TRP A 596
MET A 597
LEU A 604
ARG A 607
MET A 642
 486  A 801 (-3.7A)
486  A 801 (-2.8A)
None
None
CPS  A 803 ( 3.9A)
486  A 801 ( 3.8A)
486  A 801 (-3.5A)
486  A 801 ( 3.8A)
 0.71A 3h52C-5uc1A:
20.2		 3h52C-5uc1A:
87.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3H52_C_486C4_1
(GLUCOCORTICOID
RECEPTOR)		 5uc1 GLUCOCORTICOID
RECEPTOR
(Heterocephalus
glaber) 		5 / 12 GLY A 564
GLN A 566
VAL A 567
TRP A 596
MET A 597
 486  A 801 ( 3.8A)
486  A 801 (-2.8A)
None
None
CPS  A 803 ( 3.9A)
 1.07A 3h52C-5uc1A:
20.2		 3h52C-5uc1A:
87.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3H52_C_486C4_1
(GLUCOCORTICOID
RECEPTOR)		 5uc1 GLUCOCORTICOID
RECEPTOR
(Heterocephalus
glaber) 		5 / 12 LEU A 559
GLY A 563
VAL A 567
MET A 597
PHE A 619
 486  A 801 (-4.7A)
486  A 801 (-3.7A)
None
CPS  A 803 ( 3.9A)
486  A 801 (-4.7A)
 1.07A 3h52C-5uc1A:
20.2		 3h52C-5uc1A:
87.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3H52_C_486C4_1
(GLUCOCORTICOID
RECEPTOR)		 5uc1 GLUCOCORTICOID
RECEPTOR
(Heterocephalus
glaber) 		5 / 12 LEU A 559
GLY A 563
VAL A 567
TRP A 596
MET A 597
 486  A 801 (-4.7A)
486  A 801 (-3.7A)
None
None
CPS  A 803 ( 3.9A)
 1.10A 3h52C-5uc1A:
20.2		 3h52C-5uc1A:
87.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3H52_C_486C4_1
(GLUCOCORTICOID
RECEPTOR)		 5uc1 GLUCOCORTICOID
RECEPTOR
(Heterocephalus
glaber) 		5 / 12 LEU A 562
TRP A 596
MET A 597
LEU A 604
MET A 642
 486  A 801 ( 4.8A)
None
CPS  A 803 ( 3.9A)
486  A 801 ( 3.8A)
486  A 801 ( 3.8A)
 1.47A 3h52C-5uc1A:
20.2		 3h52C-5uc1A:
87.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3H52_D_486D2_1
(GLUCOCORTICOID
RECEPTOR)		 5uc1 GLUCOCORTICOID
RECEPTOR
(Heterocephalus
glaber) 		8 / 12 GLY A 563
GLN A 566
VAL A 567
MET A 597
LEU A 604
ARG A 607
MET A 635
MET A 642
 486  A 801 (-3.7A)
486  A 801 (-2.8A)
None
CPS  A 803 ( 3.9A)
486  A 801 ( 3.8A)
486  A 801 (-3.5A)
486  A 801 ( 4.7A)
486  A 801 ( 3.8A)
 0.74A 3h52D-5uc1A:
21.1		 3h52D-5uc1A:
87.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3MNE_A_DEXA784_1
(GLUCOCORTICOID
RECEPTOR)		 5uc1 GLUCOCORTICOID
RECEPTOR
(Heterocephalus
glaber) 		6 / 12 ASN A 560
GLY A 563
GLN A 566
MET A 597
ARG A 607
MET A 642
 486  A 801 (-4.2A)
486  A 801 (-3.7A)
486  A 801 (-2.8A)
CPS  A 803 ( 3.9A)
486  A 801 (-3.5A)
486  A 801 ( 3.8A)
 0.83A 3mneA-5uc1A:
25.3		 3mneA-5uc1A:
90.36
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3MNE_A_DEXA784_1
(GLUCOCORTICOID
RECEPTOR)		 5uc1 GLUCOCORTICOID
RECEPTOR
(Heterocephalus
glaber) 		6 / 12 GLY A 563
GLN A 566
TRP A 596
MET A 597
ARG A 607
MET A 642
 486  A 801 (-3.7A)
486  A 801 (-2.8A)
None
CPS  A 803 ( 3.9A)
486  A 801 (-3.5A)
486  A 801 ( 3.8A)
 0.70A 3mneA-5uc1A:
25.3		 3mneA-5uc1A:
90.36
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3MNE_A_DEXA784_1
(GLUCOCORTICOID
RECEPTOR)		 5uc1 GLUCOCORTICOID
RECEPTOR
(Heterocephalus
glaber) 		6 / 12 MET A 556
ASN A 560
GLY A 563
GLN A 566
MET A 597
ARG A 607
 None
486  A 801 (-4.2A)
486  A 801 (-3.7A)
486  A 801 (-2.8A)
CPS  A 803 ( 3.9A)
486  A 801 (-3.5A)
 0.88A 3mneA-5uc1A:
25.3		 3mneA-5uc1A:
90.36
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3MNO_A_DEXA784_1
(GLUCOCORTICOID
RECEPTOR)		 5uc1 GLUCOCORTICOID
RECEPTOR
(Heterocephalus
glaber) 		5 / 12 ASN A 560
GLY A 563
GLN A 566
MET A 597
ARG A 607
 486  A 801 (-4.2A)
486  A 801 (-3.7A)
486  A 801 (-2.8A)
CPS  A 803 ( 3.9A)
486  A 801 (-3.5A)
 0.79A 3mnoA-5uc1A:
24.8		 3mnoA-5uc1A:
90.36
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3MNO_A_DEXA784_1
(GLUCOCORTICOID
RECEPTOR)		 5uc1 GLUCOCORTICOID
RECEPTOR
(Heterocephalus
glaber) 		5 / 12 GLY A 563
GLN A 566
MET A 597
ARG A 607
MET A 642
 486  A 801 (-3.7A)
486  A 801 (-2.8A)
CPS  A 803 ( 3.9A)
486  A 801 (-3.5A)
486  A 801 ( 3.8A)
 0.67A 3mnoA-5uc1A:
24.8		 3mnoA-5uc1A:
90.36
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3MNP_A_DEXA784_1
(GLUCOCORTICOID
RECEPTOR)		 5uc1 GLUCOCORTICOID
RECEPTOR
(Heterocephalus
glaber) 		5 / 12 ASN A 560
GLY A 563
GLN A 566
MET A 597
ARG A 607
 486  A 801 (-4.2A)
486  A 801 (-3.7A)
486  A 801 (-2.8A)
CPS  A 803 ( 3.9A)
486  A 801 (-3.5A)
 0.78A 3mnpA-5uc1A:
25.4		 3mnpA-5uc1A:
90.36
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3MNP_A_DEXA784_1
(GLUCOCORTICOID
RECEPTOR)		 5uc1 GLUCOCORTICOID
RECEPTOR
(Heterocephalus
glaber) 		5 / 12 GLY A 563
GLN A 566
MET A 597
ARG A 607
MET A 642
 486  A 801 (-3.7A)
486  A 801 (-2.8A)
CPS  A 803 ( 3.9A)
486  A 801 (-3.5A)
486  A 801 ( 3.8A)
 0.71A 3mnpA-5uc1A:
25.4		 3mnpA-5uc1A:
90.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OLL_A_ESTA600_1
(ESTROGEN RECEPTOR
BETA)		 5uc1 GLUCOCORTICOID
RECEPTOR
(Heterocephalus
glaber) 		5 / 10 LEU A 559
LEU A 562
MET A 597
LEU A 604
ARG A 607
 486  A 801 (-4.7A)
486  A 801 ( 4.8A)
CPS  A 803 ( 3.9A)
486  A 801 ( 3.8A)
486  A 801 (-3.5A)
 0.78A 3ollA-5uc1A:
21.9		 3ollA-5uc1A:
16.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OLS_A_ESTA600_1
(ESTROGEN RECEPTOR
BETA)		 5uc1 GLUCOCORTICOID
RECEPTOR
(Heterocephalus
glaber) 		5 / 12 LEU A 559
LEU A 562
MET A 597
LEU A 604
ARG A 607
 486  A 801 (-4.7A)
486  A 801 ( 4.8A)
CPS  A 803 ( 3.9A)
486  A 801 ( 3.8A)
486  A 801 (-3.5A)
 0.82A 3olsA-5uc1A:
23.1		 3olsA-5uc1A:
16.30
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3VHU_A_SNLA1001_1
(MINERALOCORTICOID
RECEPTOR)		 5uc1 GLUCOCORTICOID
RECEPTOR
(Heterocephalus
glaber) 		5 / 12 ASN A 560
GLN A 566
MET A 597
LEU A 604
ARG A 607
 486  A 801 (-4.2A)
486  A 801 (-2.8A)
CPS  A 803 ( 3.9A)
486  A 801 ( 3.8A)
486  A 801 (-3.5A)
 0.73A 3vhuA-5uc1A:
23.4		 3vhuA-5uc1A:
44.74
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3ZQT_A_TESA1000_1
(ANDROGEN RECEPTOR)		 5uc1 GLUCOCORTICOID
RECEPTOR
(Heterocephalus
glaber) 		5 / 12 LEU A 559
ASN A 560
MET A 597
MET A 600
ARG A 607
 486  A 801 (-4.7A)
486  A 801 (-4.2A)
CPS  A 803 ( 3.9A)
None
486  A 801 (-3.5A)
 0.85A 3zqtA-5uc1A:
23.3		 3zqtA-5uc1A:
50.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C5L_A_UEGA300_1
(PHOSPHOMETHYLPYRIMID
INE KINASE)		 4czt CBL-INTERACTING
SERINE/THREONINE-PRO
TEIN KINASE 23
(Arabidopsis
thaliana) 		5 / 11 GLY A 113
ASP A 163
ALA A 167
GLY A 166
VAL A 111
 CPS  A1316 (-3.9A)
SO4  A1318 (-4.6A)
None
None
SO4  A1318 (-3.8A)
 1.13A 4c5lA-4cztA:
undetectable		 4c5lA-4cztA:
21.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C5L_B_PXLB300_1
(PHOSPHOMETHYLPYRIMID
INE KINASE)		 4czt CBL-INTERACTING
SERINE/THREONINE-PRO
TEIN KINASE 23
(Arabidopsis
thaliana) 		5 / 9 GLY A 113
ASP A 163
ALA A 167
GLY A 166
VAL A 111
 CPS  A1316 (-3.9A)
SO4  A1318 (-4.6A)
None
None
SO4  A1318 (-3.8A)
 1.16A 4c5lB-4cztA:
undetectable		 4c5lB-4cztA:
21.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C5L_C_UEGC300_1
(PHOSPHOMETHYLPYRIMID
INE KINASE)		 4czt CBL-INTERACTING
SERINE/THREONINE-PRO
TEIN KINASE 23
(Arabidopsis
thaliana) 		5 / 10 GLY A 113
ASP A 163
ALA A 167
GLY A 166
VAL A 111
 CPS  A1316 (-3.9A)
SO4  A1318 (-4.6A)
None
None
SO4  A1318 (-3.8A)
 1.11A 4c5lC-4cztA:
undetectable		 4c5lC-4cztA:
21.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C5L_D_UEGD300_1
(PHOSPHOMETHYLPYRIMID
INE KINASE)		 4czt CBL-INTERACTING
SERINE/THREONINE-PRO
TEIN KINASE 23
(Arabidopsis
thaliana) 		5 / 10 GLY A 113
ASP A 163
ALA A 167
GLY A 166
VAL A 111
 CPS  A1316 (-3.9A)
SO4  A1318 (-4.6A)
None
None
SO4  A1318 (-3.8A)
 1.13A 4c5lD-4cztA:
undetectable		 4c5lD-4cztA:
21.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C5N_B_PXLB300_1
(PHOSPHOMETHYLPYRIMID
INE KINASE)		 4czt CBL-INTERACTING
SERINE/THREONINE-PRO
TEIN KINASE 23
(Arabidopsis
thaliana) 		5 / 10 GLY A 113
ASP A 163
ALA A 167
GLY A 166
VAL A 111
 CPS  A1316 (-3.9A)
SO4  A1318 (-4.6A)
None
None
SO4  A1318 (-3.8A)
 1.16A 4c5nB-4cztA:
undetectable		 4c5nB-4cztA:
21.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C5N_D_UEGD300_1
(PHOSPHOMETHYLPYRIMID
INE KINASE)		 4czt CBL-INTERACTING
SERINE/THREONINE-PRO
TEIN KINASE 23
(Arabidopsis
thaliana) 		5 / 10 GLY A 113
ASP A 163
ALA A 167
GLY A 166
VAL A 111
 CPS  A1316 (-3.9A)
SO4  A1318 (-4.6A)
None
None
SO4  A1318 (-3.8A)
 1.14A 4c5nD-4cztA:
undetectable		 4c5nD-4cztA:
21.02
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4FN9_A_STRA301_1
(STEROID RECEPTOR 2)		 5uc1 GLUCOCORTICOID
RECEPTOR
(Heterocephalus
glaber) 		7 / 12 LEU A 559
ASN A 560
LEU A 562
GLN A 566
MET A 597
ALA A 601
ARG A 607
 486  A 801 (-4.7A)
486  A 801 (-4.2A)
486  A 801 ( 4.8A)
486  A 801 (-2.8A)
CPS  A 803 ( 3.9A)
CPS  A 803 ( 3.9A)
486  A 801 (-3.5A)
 0.76A 4fn9A-5uc1A:
25.1		 4fn9A-5uc1A:
61.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4FN9_B_STRB301_1
(STEROID RECEPTOR 2)		 5uc1 GLUCOCORTICOID
RECEPTOR
(Heterocephalus
glaber) 		6 / 12 LEU A 559
ASN A 560
LEU A 562
GLN A 566
MET A 597
ARG A 607
 486  A 801 (-4.7A)
486  A 801 (-4.2A)
486  A 801 ( 4.8A)
486  A 801 (-2.8A)
CPS  A 803 ( 3.9A)
486  A 801 (-3.5A)
 0.76A 4fn9B-5uc1A:
25.4		 4fn9B-5uc1A:
61.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4FN9_B_STRB301_1
(STEROID RECEPTOR 2)		 5uc1 GLUCOCORTICOID
RECEPTOR
(Heterocephalus
glaber) 		5 / 12 LEU A 562
GLN A 566
TRP A 596
MET A 597
ARG A 607
 486  A 801 ( 4.8A)
486  A 801 (-2.8A)
None
CPS  A 803 ( 3.9A)
486  A 801 (-3.5A)
 0.74A 4fn9B-5uc1A:
25.4		 4fn9B-5uc1A:
61.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4HLW_A_TESA1001_1
(ANDROGEN RECEPTOR)		 5uc1 GLUCOCORTICOID
RECEPTOR
(Heterocephalus
glaber) 		5 / 12 GLN A 566
TRP A 596
MET A 597
MET A 600
ARG A 607
 486  A 801 (-2.8A)
None
CPS  A 803 ( 3.9A)
None
486  A 801 (-3.5A)
 0.69A 4hlwA-5uc1A:
23.1		 4hlwA-5uc1A:
50.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4HLW_A_TESA1001_1
(ANDROGEN RECEPTOR)		 5uc1 GLUCOCORTICOID
RECEPTOR
(Heterocephalus
glaber) 		7 / 12 LEU A 559
ASN A 560
GLY A 563
GLN A 566
MET A 597
MET A 600
ARG A 607
 486  A 801 (-4.7A)
486  A 801 (-4.2A)
486  A 801 (-3.7A)
486  A 801 (-2.8A)
CPS  A 803 ( 3.9A)
None
486  A 801 (-3.5A)
 0.79A 4hlwA-5uc1A:
23.1		 4hlwA-5uc1A:
50.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4LTW_A_STRA301_1
(ANCESTRAL STEROID
RECEPTOR 2)		 5uc1 GLUCOCORTICOID
RECEPTOR
(Heterocephalus
glaber) 		6 / 12 LEU A 559
ASN A 560
LEU A 562
GLN A 566
MET A 597
ARG A 607
 486  A 801 (-4.7A)
486  A 801 (-4.2A)
486  A 801 ( 4.8A)
486  A 801 (-2.8A)
CPS  A 803 ( 3.9A)
486  A 801 (-3.5A)
 0.81A 4ltwA-5uc1A:
25.2		 4ltwA-5uc1A:
61.25
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4LTW_A_STRA301_2
(ANCESTRAL STEROID
RECEPTOR 2)		 5uc1 GLUCOCORTICOID
RECEPTOR
(Heterocephalus
glaber) 		4 / 8 TRP A 596
MET A 600
ALA A 601
MET A 642
 None
None
CPS  A 803 ( 3.9A)
486  A 801 ( 3.8A)
 0.41A 4ltwA-5uc1A:
25.2		 4ltwA-5uc1A:
61.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MI4_A_SPMA201_1
(SPERMIDINE
N1-ACETYLTRANSFERASE)		 2pun METHYLTHIORIBOSE
KINASE
(Bacillus
subtilis) 		4 / 6 ASN A 290
GLU A 283
TYR A 286
GLU A 389
 None
None
None
CPS  A 777 (-3.5A)
 1.00A 4mi4A-2punA:
undetectable		 4mi4A-2punA:
20.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MI4_B_SPMB201_1
(SPERMIDINE
N1-ACETYLTRANSFERASE)		 2pun METHYLTHIORIBOSE
KINASE
(Bacillus
subtilis) 		4 / 7 ASN A 290
GLU A 283
TYR A 286
GLU A 389
 None
None
None
CPS  A 777 (-3.5A)
 1.00A 4mi4B-2punA:
undetectable
4mi4C-2punA:
undetectable		 4mi4B-2punA:
20.15
4mi4C-2punA:
20.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MI4_C_SPMC201_1
(SPERMIDINE
N1-ACETYLTRANSFERASE)		 2pun METHYLTHIORIBOSE
KINASE
(Bacillus
subtilis) 		4 / 7 ASN A 290
GLU A 283
TYR A 286
GLU A 389
 None
None
None
CPS  A 777 (-3.5A)
 0.99A 4mi4A-2punA:
undetectable
4mi4C-2punA:
undetectable		 4mi4A-2punA:
20.15
4mi4C-2punA:
20.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MJ8_A_SPMA201_1
(SPERMIDINE
N1-ACETYLTRANSFERASE)		 2pun METHYLTHIORIBOSE
KINASE
(Bacillus
subtilis) 		4 / 8 ASN A 290
GLU A 283
TYR A 286
GLU A 389
 None
None
None
CPS  A 777 (-3.5A)
 0.99A 4mj8A-2punA:
undetectable
4mj8C-2punA:
undetectable		 4mj8A-2punA:
19.84
4mj8C-2punA:
19.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MJ8_B_SPMB201_1
(SPERMIDINE
N1-ACETYLTRANSFERASE)		 2pun METHYLTHIORIBOSE
KINASE
(Bacillus
subtilis) 		4 / 8 ASN A 290
GLU A 283
TYR A 286
GLU A 389
 None
None
None
CPS  A 777 (-3.5A)
 0.99A 4mj8B-2punA:
undetectable
4mj8C-2punA:
undetectable		 4mj8B-2punA:
19.84
4mj8C-2punA:
19.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MJ8_C_SPMC201_1
(SPERMIDINE
N1-ACETYLTRANSFERASE)		 2pun METHYLTHIORIBOSE
KINASE
(Bacillus
subtilis) 		4 / 7 ASN A 290
GLU A 283
TYR A 286
GLU A 389
 None
None
None
CPS  A 777 (-3.5A)
 0.98A 4mj8C-2punA:
undetectable		 4mj8C-2punA:
19.84
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4OJB_A_198A1001_1
(ANDROGEN RECEPTOR)		 5uc1 GLUCOCORTICOID
RECEPTOR
(Heterocephalus
glaber) 		5 / 12 GLY A 563
GLN A 566
MET A 597
MET A 600
ARG A 607
 486  A 801 (-3.7A)
486  A 801 (-2.8A)
CPS  A 803 ( 3.9A)
None
486  A 801 (-3.5A)
 0.72A 4ojbA-5uc1A:
22.6		 4ojbA-5uc1A:
30.37
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4OK1_A_198A1001_1
(ANDROGEN RECEPTOR)		 5uc1 GLUCOCORTICOID
RECEPTOR
(Heterocephalus
glaber) 		5 / 12 LEU A 559
GLY A 563
GLN A 566
MET A 597
ARG A 607
 486  A 801 (-4.7A)
486  A 801 (-3.7A)
486  A 801 (-2.8A)
CPS  A 803 ( 3.9A)
486  A 801 (-3.5A)
 0.83A 4ok1A-5uc1A:
23.2		 4ok1A-5uc1A:
30.37
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4OKB_A_198A1002_1
(ANDROGEN RECEPTOR)		 5uc1 GLUCOCORTICOID
RECEPTOR
(Heterocephalus
glaber) 		5 / 12 GLY A 563
GLN A 566
MET A 597
MET A 600
ARG A 607
 486  A 801 (-3.7A)
486  A 801 (-2.8A)
CPS  A 803 ( 3.9A)
None
486  A 801 (-3.5A)
 0.80A 4okbA-5uc1A:
22.5		 4okbA-5uc1A:
30.37
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4OKT_A_198A1001_1
(ANDROGEN RECEPTOR)		 5uc1 GLUCOCORTICOID
RECEPTOR
(Heterocephalus
glaber) 		6 / 12 LEU A 559
GLY A 563
GLN A 566
MET A 597
ARG A 607
MET A 642
 486  A 801 (-4.7A)
486  A 801 (-3.7A)
486  A 801 (-2.8A)
CPS  A 803 ( 3.9A)
486  A 801 (-3.5A)
486  A 801 ( 3.8A)
 0.98A 4oktA-5uc1A:
22.9		 4oktA-5uc1A:
30.37
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4OKW_A_198A1001_1
(ANDROGEN RECEPTOR)		 5uc1 GLUCOCORTICOID
RECEPTOR
(Heterocephalus
glaber) 		5 / 12 GLY A 563
GLN A 566
MET A 597
MET A 600
ARG A 607
 486  A 801 (-3.7A)
486  A 801 (-2.8A)
CPS  A 803 ( 3.9A)
None
486  A 801 (-3.5A)
 0.72A 4okwA-5uc1A:
22.7		 4okwA-5uc1A:
30.37
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4OKX_A_198A1002_1
(ANDROGEN RECEPTOR)		 5uc1 GLUCOCORTICOID
RECEPTOR
(Heterocephalus
glaber) 		5 / 12 GLY A 563
GLN A 566
MET A 597
MET A 600
ARG A 607
 486  A 801 (-3.7A)
486  A 801 (-2.8A)
CPS  A 803 ( 3.9A)
None
486  A 801 (-3.5A)
 0.72A 4okxA-5uc1A:
22.5		 4okxA-5uc1A:
30.37
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4OLM_A_198A1001_1
(ANDROGEN RECEPTOR)		 5uc1 GLUCOCORTICOID
RECEPTOR
(Heterocephalus
glaber) 		5 / 12 GLY A 563
GLN A 566
MET A 597
MET A 600
ARG A 607
 486  A 801 (-3.7A)
486  A 801 (-2.8A)
CPS  A 803 ( 3.9A)
None
486  A 801 (-3.5A)
 0.81A 4olmA-5uc1A:
22.2		 4olmA-5uc1A:
30.37
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4P6X_A_HCYA900_1
(GLUCOCORTICOID
RECEPTOR)		 5uc1 GLUCOCORTICOID
RECEPTOR
(Heterocephalus
glaber) 		7 / 12 LEU A 559
ASN A 560
GLY A 563
GLN A 566
MET A 597
LEU A 604
ARG A 607
 486  A 801 (-4.7A)
486  A 801 (-4.2A)
486  A 801 (-3.7A)
486  A 801 (-2.8A)
CPS  A 803 ( 3.9A)
486  A 801 ( 3.8A)
486  A 801 (-3.5A)
 0.86A 4p6xA-5uc1A:
26.4		 4p6xA-5uc1A:
96.15
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4P6X_C_HCYC900_1
(GLUCOCORTICOID
RECEPTOR)		 5uc1 GLUCOCORTICOID
RECEPTOR
(Heterocephalus
glaber) 		6 / 11 ASN A 560
LEU A 562
GLN A 566
MET A 597
MET A 600
ARG A 607
 486  A 801 (-4.2A)
486  A 801 ( 4.8A)
486  A 801 (-2.8A)
CPS  A 803 ( 3.9A)
None
486  A 801 (-3.5A)
 0.88A 4p6xC-5uc1A:
26.6		 4p6xC-5uc1A:
96.15
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4P6X_C_HCYC900_1
(GLUCOCORTICOID
RECEPTOR)		 5uc1 GLUCOCORTICOID
RECEPTOR
(Heterocephalus
glaber) 		6 / 11 LEU A 562
GLN A 566
TRP A 596
MET A 597
MET A 600
ARG A 607
 486  A 801 ( 4.8A)
486  A 801 (-2.8A)
None
CPS  A 803 ( 3.9A)
None
486  A 801 (-3.5A)
 0.92A 4p6xC-5uc1A:
26.6		 4p6xC-5uc1A:
96.15
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4P6X_E_HCYE900_1
(GLUCOCORTICOID
RECEPTOR)		 5uc1 GLUCOCORTICOID
RECEPTOR
(Heterocephalus
glaber) 		8 / 12 LEU A 559
ASN A 560
GLY A 563
GLN A 566
MET A 597
MET A 600
LEU A 604
ARG A 607
 486  A 801 (-4.7A)
486  A 801 (-4.2A)
486  A 801 (-3.7A)
486  A 801 (-2.8A)
CPS  A 803 ( 3.9A)
None
486  A 801 ( 3.8A)
486  A 801 (-3.5A)
 0.90A 4p6xE-5uc1A:
26.3		 4p6xE-5uc1A:
96.15
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4P6X_G_HCYG900_1
(GLUCOCORTICOID
RECEPTOR)		 5uc1 GLUCOCORTICOID
RECEPTOR
(Heterocephalus
glaber) 		7 / 12 ASN A 560
GLY A 563
GLN A 566
MET A 597
LEU A 604
ARG A 607
MET A 642
 486  A 801 (-4.2A)
486  A 801 (-3.7A)
486  A 801 (-2.8A)
CPS  A 803 ( 3.9A)
486  A 801 ( 3.8A)
486  A 801 (-3.5A)
486  A 801 ( 3.8A)
 0.73A 4p6xG-5uc1A:
26.7		 4p6xG-5uc1A:
96.15
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4P6X_G_HCYG900_1
(GLUCOCORTICOID
RECEPTOR)		 5uc1 GLUCOCORTICOID
RECEPTOR
(Heterocephalus
glaber) 		7 / 12 GLY A 563
GLN A 566
TRP A 596
MET A 597
LEU A 604
ARG A 607
MET A 642
 486  A 801 (-3.7A)
486  A 801 (-2.8A)
None
CPS  A 803 ( 3.9A)
486  A 801 ( 3.8A)
486  A 801 (-3.5A)
486  A 801 ( 3.8A)
 0.75A 4p6xG-5uc1A:
26.7		 4p6xG-5uc1A:
96.15
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4P6X_I_HCYI900_1
(GLUCOCORTICOID
RECEPTOR)		 5uc1 GLUCOCORTICOID
RECEPTOR
(Heterocephalus
glaber) 		8 / 12 LEU A 559
ASN A 560
GLY A 563
GLN A 566
MET A 597
LEU A 604
ARG A 607
MET A 642
 486  A 801 (-4.7A)
486  A 801 (-4.2A)
486  A 801 (-3.7A)
486  A 801 (-2.8A)
CPS  A 803 ( 3.9A)
486  A 801 ( 3.8A)
486  A 801 (-3.5A)
486  A 801 ( 3.8A)
 0.83A 4p6xI-5uc1A:
26.8		 4p6xI-5uc1A:
96.15
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4P6X_K_HCYK900_1
(GLUCOCORTICOID
RECEPTOR)		 5uc1 GLUCOCORTICOID
RECEPTOR
(Heterocephalus
glaber) 		6 / 12 ASN A 560
GLY A 563
GLN A 566
MET A 597
ARG A 607
MET A 642
 486  A 801 (-4.2A)
486  A 801 (-3.7A)
486  A 801 (-2.8A)
CPS  A 803 ( 3.9A)
486  A 801 (-3.5A)
486  A 801 ( 3.8A)
 0.78A 4p6xK-5uc1A:
26.7		 4p6xK-5uc1A:
96.15
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4P6X_K_HCYK900_1
(GLUCOCORTICOID
RECEPTOR)		 5uc1 GLUCOCORTICOID
RECEPTOR
(Heterocephalus
glaber) 		6 / 12 GLY A 563
GLN A 566
TRP A 596
MET A 597
ARG A 607
MET A 642
 486  A 801 (-3.7A)
486  A 801 (-2.8A)
None
CPS  A 803 ( 3.9A)
486  A 801 (-3.5A)
486  A 801 ( 3.8A)
 0.81A 4p6xK-5uc1A:
26.7		 4p6xK-5uc1A:
96.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R87_I_SPMI202_1
(SPERMIDINE
N1-ACETYLTRANSFERASE)		 2pun METHYLTHIORIBOSE
KINASE
(Bacillus
subtilis) 		4 / 7 ASN A 290
GLU A 283
TYR A 286
GLU A 389
 None
None
None
CPS  A 777 (-3.5A)
 1.07A 4r87I-2punA:
undetectable		 4r87I-2punA:
19.84
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4UDA_A_DEXA1985_1
(MINERALOCORTICOID
RECEPTOR)		 5uc1 GLUCOCORTICOID
RECEPTOR
(Heterocephalus
glaber) 		5 / 12 ASN A 560
GLN A 566
MET A 597
ARG A 607
MET A 642
 486  A 801 (-4.2A)
486  A 801 (-2.8A)
CPS  A 803 ( 3.9A)
486  A 801 (-3.5A)
486  A 801 ( 3.8A)
 0.92A 4udaA-5uc1A:
23.5		 4udaA-5uc1A:
53.75
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4UDC_A_DEXA1778_1
(GLUCOCORTICOID
RECEPTOR)		 5uc1 GLUCOCORTICOID
RECEPTOR
(Heterocephalus
glaber) 		6 / 12 GLY A 563
GLN A 566
TRP A 596
MET A 597
ARG A 607
MET A 642
 486  A 801 (-3.7A)
486  A 801 (-2.8A)
None
CPS  A 803 ( 3.9A)
486  A 801 (-3.5A)
486  A 801 ( 3.8A)
 0.73A 4udcA-5uc1A:
26.8		 4udcA-5uc1A:
75.49
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4UDC_A_DEXA1778_1
(GLUCOCORTICOID
RECEPTOR)		 5uc1 GLUCOCORTICOID
RECEPTOR
(Heterocephalus
glaber) 		8 / 12 MET A 556
LEU A 559
ASN A 560
GLY A 563
GLN A 566
MET A 597
ARG A 607
MET A 642
 None
486  A 801 (-4.7A)
486  A 801 (-4.2A)
486  A 801 (-3.7A)
486  A 801 (-2.8A)
CPS  A 803 ( 3.9A)
486  A 801 (-3.5A)
486  A 801 ( 3.8A)
 0.90A 4udcA-5uc1A:
26.8		 4udcA-5uc1A:
75.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IZJ_G_AZ1G2_1
(CAMP-DEPENDENT
PROTEIN KINASE
CATALYTIC SUBUNIT
ALPHA
47P-AZ1-DAR-DAR)		 4czt CBL-INTERACTING
SERINE/THREONINE-PRO
TEIN KINASE 23
(Arabidopsis
thaliana) 		4 / 7 GLY A  38
GLY A  40
VAL A  45
LYS A  60
 None
None
None
CPS  A1316 ( 4.8A)
 0.48A 5izjA-4cztA:
19.6		 5izjA-4cztA:
27.56
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5NFP_A_8W5A804_1
(GLUCOCORTICOID
RECEPTOR)		 5uc1 GLUCOCORTICOID
RECEPTOR
(Heterocephalus
glaber) 		10 / 12 MET A 556
ASN A 560
GLY A 563
GLN A 566
MET A 597
ARG A 607
MET A 635
GLN A 638
CYH A 639
MET A 642
 None
486  A 801 (-4.2A)
486  A 801 (-3.7A)
486  A 801 (-2.8A)
CPS  A 803 ( 3.9A)
486  A 801 (-3.5A)
486  A 801 ( 4.7A)
486  A 801 (-4.6A)
486  A 801 ( 3.9A)
486  A 801 ( 3.8A)
 0.83A 5nfpA-5uc1A:
26.7		 5nfpA-5uc1A:
81.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OV9_B_CVIB602_0
(ACETYLCHOLINESTERASE)		 4czt CBL-INTERACTING
SERINE/THREONINE-PRO
TEIN KINASE 23
(Arabidopsis
thaliana) 		4 / 8 ASP A 172
LEU A 175
THR A 190
VAL A  45
 CPS  A1316 (-3.9A)
None
None
None
 1.12A 5ov9B-4cztA:
undetectable		 5ov9B-4cztA:
22.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TOA_A_ESTA601_1
(ESTROGEN RECEPTOR
BETA)		 5uc1 GLUCOCORTICOID
RECEPTOR
(Heterocephalus
glaber) 		5 / 12 LEU A 559
LEU A 562
MET A 597
LEU A 604
ARG A 607
 486  A 801 (-4.7A)
486  A 801 ( 4.8A)
CPS  A 803 ( 3.9A)
486  A 801 ( 3.8A)
486  A 801 (-3.5A)
 0.80A 5toaA-5uc1A:
22.9		 5toaA-5uc1A:
16.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5U63_A_ACTA406_0
(THIOREDOXIN
REDUCTASE)		 4czt CBL-INTERACTING
SERINE/THREONINE-PRO
TEIN KINASE 23
(Arabidopsis
thaliana) 		3 / 3 HIS A 152
SER A 171
ARG A 183
 None
CPS  A1316 (-4.0A)
None
 0.96A 5u63A-4cztA:
undetectable		 5u63A-4cztA:
22.90
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5UC3_A_486A801_2
(GLUCOCORTICOID
RECEPTOR)		 5uc1 GLUCOCORTICOID
RECEPTOR
(Heterocephalus
glaber) 		4 / 5 LEU A 559
LEU A 562
MET A 597
GLN A 638
 486  A 801 (-4.7A)
486  A 801 ( 4.8A)
CPS  A 803 ( 3.9A)
486  A 801 (-4.6A)
 0.98A 5uc3A-5uc1A:
28.2		 5uc3A-5uc1A:
96.25