SIMILAR PATTERN OF AMINO ACIDS MAPPED TO 'CPL'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2RLC_A_CHDA332_0 (CHOLOYLGLYCINE HYDROLASE)	2w6d	DYNAMIN FAMILY PROTEIN (Nostoc punctiforme)	5 / 12	THR A 565 ASN A 427 ILE A 561 ILE A 452 LEU A 426	CPL A1705 (-3.7A) None CPL A1705 (-1.2A) CPL A1705 ( 4.8A) CPL A1708 (-4.9A)	1.17A	2rlcA-2w6dA: undetectable	2rlcA-2w6dA: 19.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3CFL_A_5CHA693_1 (LACTOTRANSFERRIN)	2w6d	DYNAMIN FAMILY PROTEIN (Nostoc punctiforme)	4 / 4	THR A 565 VAL A 608 GLY A 556 THR A 553	CPL A1705 (-3.7A) None None None	1.09A	3cflA-2w6dA: undetectable	3cflA-2w6dA: 18.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5X19_J_CHDJ101_0 (CYTOCHROME C OXIDASE SUBUNIT 7A1, MITOCHONDRIAL)	2w6d	DYNAMIN FAMILY PROTEIN (Nostoc punctiforme)	4 / 5	TYR A 422 ARG A 421 THR A 414 LEU A 411	None CPL A1701 (-4.4A) CPL A1701 (-1.4A) None	1.22A	5x19J-2w6dA: undetectable	5x19J-2w6dA: 7.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5X1B_J_CHDJ101_0 (CYTOCHROME C OXIDASE SUBUNIT 7A1, MITOCHONDRIAL)	2w6d	DYNAMIN FAMILY PROTEIN (Nostoc punctiforme)	4 / 5	TYR A 422 ARG A 421 THR A 414 LEU A 411	None CPL A1701 (-4.4A) CPL A1701 (-1.4A) None	1.26A	5x1bJ-2w6dA: undetectable	5x1bJ-2w6dA: 7.18

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["2RLC_A_CHDA332_0","CHOLOYLGLYCINE HYDROLASE","2w6d","DYNAMIN FAMILY PROTEIN","Nostoc punctiforme",5,"THR A 565;ASN A 427;ILE A 561;ILE A 452;LEU A 426","CPL A1705 (-3.7A);None;CPL A1705 (-1.2A);CPL A1705 ( 4.8A);CPL A1708 (-4.9A)","1.17A","2rlcA-2w6dA:undetectable",null],["3CFL_A_5CHA693_1","LACTOTRANSFERRIN","2w6d","DYNAMIN FAMILY PROTEIN","Nostoc punctiforme",4,"THR A 565;VAL A 608;GLY A 556;THR A 553","CPL A1705 (-3.7A);None;None;None","1.09A","3cflA-2w6dA:undetectable","2rlcA-2w6dA:19.79"],["5X19_J_CHDJ101_0","CYTOCHROME C OXIDASE SUBUNIT 7A1, MITOCHONDRIAL","2w6d","DYNAMIN FAMILY PROTEIN","Nostoc punctiforme",4,"TYR A 422;ARG A 421;THR A 414;LEU A 411","None;CPL A1701 (-4.4A);CPL A1701 (-1.4A);None","1.22A","5x19J-2w6dA:undetectable","3cflA-2w6dA:18.79"],["5X1B_J_CHDJ101_0","CYTOCHROME C OXIDASE SUBUNIT 7A1, MITOCHONDRIAL","2w6d","DYNAMIN FAMILY PROTEIN","Nostoc punctiforme",4,"TYR A 422;ARG A 421;THR A 414;LEU A 411","None;CPL A1701 (-4.4A);CPL A1701 (-1.4A);None","1.26A","5x1bJ-2w6dA:undetectable","5x19J-2w6dA:7.18"]]