SIMILAR PATTERN OF AMINO ACIDS MAPPED TO 'CPF'


List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1CEA_A_ACAA90_1
(PLASMINOGEN)		 4bvv APOLIPOPROTEIN(A)
(Homo
sapiens) 		4 / 8 ASP A  55
ASP A  57
TRP A  62
TYR A  64
 CPF  A1081 (-3.1A)
CPF  A1081 (-3.9A)
CPF  A1081 (-3.6A)
CPF  A1081 (-4.8A)
 0.42A 1ceaA-4bvvA:
undetectable
1ceaB-4bvvA:
16.7		 1ceaA-4bvvA:
53.01
1ceaB-4bvvA:
53.01
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1CEA_B_ACAB90_1
(PLASMINOGEN)		 4bvv APOLIPOPROTEIN(A)
(Homo
sapiens) 		4 / 7 ASP A  55
ASP A  57
TRP A  62
TYR A  64
 CPF  A1081 (-3.1A)
CPF  A1081 (-3.9A)
CPF  A1081 (-3.6A)
CPF  A1081 (-4.8A)
 0.36A 1ceaB-4bvvA:
16.7		 1ceaB-4bvvA:
53.01
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1CEB_A_AMHA90_1
(PLASMINOGEN)		 4bvv APOLIPOPROTEIN(A)
(Homo
sapiens) 		4 / 7 ASP A  55
ASP A  57
TRP A  62
TYR A  64
 CPF  A1081 (-3.1A)
CPF  A1081 (-3.9A)
CPF  A1081 (-3.6A)
CPF  A1081 (-4.8A)
 0.40A 1cebA-4bvvA:
16.7		 1cebA-4bvvA:
53.01
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1CEB_B_AMHB90_1
(PLASMINOGEN)		 4bvv APOLIPOPROTEIN(A)
(Homo
sapiens) 		4 / 7 ASP A  55
ASP A  57
TRP A  62
TYR A  64
 CPF  A1081 (-3.1A)
CPF  A1081 (-3.9A)
CPF  A1081 (-3.6A)
CPF  A1081 (-4.8A)
 0.47A 1cebB-4bvvA:
16.8		 1cebB-4bvvA:
53.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MB5_A_NMYA301_0
(AAC(3)-IIIB PROTEIN)		 4bvv APOLIPOPROTEIN(A)
(Homo
sapiens) 		5 / 11 TYR A   9
ASP A  73
THR A  16
GLY A  60
ASP A  57
 SO4  A1082 (-4.7A)
None
None
None
CPF  A1081 (-3.9A)
 1.35A 6mb5A-4bvvA:
undetectable		 6mb5A-4bvvA:
16.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MB9_A_NMYA303_0
(AAC(3)-IIIB PROTEIN)		 4bvv APOLIPOPROTEIN(A)
(Homo
sapiens) 		5 / 10 TYR A   9
ASP A  73
THR A  16
GLY A  60
ASP A  57
 SO4  A1082 (-4.7A)
None
None
None
CPF  A1081 (-3.9A)
 1.38A 6mb9A-4bvvA:
undetectable		 6mb9A-4bvvA:
16.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MB9_B_NMYB302_0
(AAC(3)-IIIB PROTEIN)		 4bvv APOLIPOPROTEIN(A)
(Homo
sapiens) 		5 / 10 TYR A   9
ASP A  73
THR A  16
GLY A  60
ASP A  57
 SO4  A1082 (-4.7A)
None
None
None
CPF  A1081 (-3.9A)
 1.38A 6mb9B-4bvvA:
undetectable		 6mb9B-4bvvA:
16.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MB9_C_NMYC302_0
(AAC(3)-IIIB PROTEIN)		 4bvv APOLIPOPROTEIN(A)
(Homo
sapiens) 		5 / 10 TYR A   9
ASP A  73
THR A  16
GLY A  60
ASP A  57
 SO4  A1082 (-4.7A)
None
None
None
CPF  A1081 (-3.9A)
 1.39A 6mb9C-4bvvA:
undetectable		 6mb9C-4bvvA:
16.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MB9_D_NMYD302_0
(AAC(3)-IIIB PROTEIN)		 4bvv APOLIPOPROTEIN(A)
(Homo
sapiens) 		5 / 10 TYR A   9
ASP A  73
THR A  16
GLY A  60
ASP A  57
 SO4  A1082 (-4.7A)
None
None
None
CPF  A1081 (-3.9A)
 1.40A 6mb9D-4bvvA:
undetectable		 6mb9D-4bvvA:
16.28