SIMILAR PATTERN OF AMINO ACIDS MAPPED TO 'COT'

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)	View	Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1EQG_B_IBPB1701_1 (PROSTAGLANDIN H2 SYNTHASE-1)	1cjw	PROTEIN (SEROTONIN N-ACETYLTRANSFERASE) (Ovis aries)	6 / 11	VAL A  48 SER A  81 LEU A  74 ILE A  94 ALA A 123 LEU A  65	None None None None COT  A 400 (-4.1A) None	1.14A	1eqgB-1cjwA: 0.0	1eqgB-1cjwA: 15.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1EQG_B_IBPB1701_1 (PROSTAGLANDIN H2 SYNTHASE-1)	1ib1	SEROTONIN N-ACETYLTRANSFERASE (Ovis aries)	5 / 11	VAL E  48 SER E  81 LEU E  74 ILE E  94 ALA E 123	None None None None COT  E 401 (-4.1A)	0.99A	1eqgB-1ib1E: undetectable	1eqgB-1ib1E: 16.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3LBD_A_9CRA424_1 (RETINOIC ACID RECEPTOR GAMMA)	1cjw	PROTEIN (SEROTONIN N-ACETYLTRANSFERASE) (Ovis aries)	5 / 12	ALA A  55 LEU A 124 SER A  60 GLY A 136 ILE A  51	COT  A 400 ( 4.0A) COT  A 400 (-4.5A) COT  A 400 (-3.4A) COT  A 400 (-3.5A) None	1.07A	3lbdA-1cjwA: 0.0	3lbdA-1cjwA: 21.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3LTW_A_HLZA300_1 (ARYLAMINE N-ACETYLTRANSFERASE NAT)	1cjw	PROTEIN (SEROTONIN N-ACETYLTRANSFERASE) (Ovis aries)	4 / 6	PHE A 171 TYR A 168 VAL A 126 PHE A 167	None COT  A 400 (-4.9A) COT  A 400 (-4.1A) COT  A 400 (-4.2A)	1.34A	3ltwA-1cjwA: undetectable	3ltwA-1cjwA: 21.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3LTW_A_HLZA300_1 (ARYLAMINE N-ACETYLTRANSFERASE NAT)	1ib1	SEROTONIN N-ACETYLTRANSFERASE (Ovis aries)	4 / 6	PHE E 171 TYR E 168 VAL E 126 PHE E 167	None COT  E 401 (-4.8A) COT  E 401 (-3.8A) COT  E 401 (-3.6A)	1.29A	3ltwA-1ib1E: undetectable	3ltwA-1ib1E: 20.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4LTW_A_486A303_1 (ANCESTRAL STEROID RECEPTOR 2)	1ib1	SEROTONIN N-ACETYLTRANSFERASE (Ovis aries)	5 / 9	LEU E 144 ALA E 156 GLN E 169 PHE E 173 TYR E 168	None None None None COT  E 401 (-4.8A)	1.42A	4ltwA-1ib1E: undetectable	4ltwA-1ib1E: 20.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4ZBQ_A_DIFA601_1 (SERUM ALBUMIN)	1ib1	SEROTONIN N-ACETYLTRANSFERASE (Ovis aries)	5 / 11	LEU E 164 VAL E 165 LEU E 140 GLY E 172 LEU E 158	COT  E 401 (-4.6A) None None None COT  E 401 ( 4.8A)	1.15A	4zbqA-1ib1E: undetectable	4zbqA-1ib1E: 14.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5XXI_A_LSNA501_2 (CYTOCHROME P450 2C9)	1cjw	PROTEIN (SEROTONIN N-ACETYLTRANSFERASE) (Ovis aries)	4 / 4	PHE A  85 LEU A 124 LEU A  82 VAL A 126	None COT  A 400 (-4.5A) None COT  A 400 (-4.1A)	1.28A	5xxiA-1cjwA: 0.0	5xxiA-1cjwA: 16.82