SIMILAR PATTERN OF AMINO ACIDS MAPPED TO 'COD'
DrReposER ID / Desc. | Hit PDBID |
Hit Macromolecule |
Res. Matches |
Interface | HETATM | RMSD | Dali Z-score |
Seq. Identity (%) |
View | Dock | |
---|---|---|---|---|---|---|---|---|---|---|---|
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1KLM_A_SPPA999_1 (HIV-1 REVERSETRANSCRIPTASE) |
3pxu | PHOSPHOPANTETHEINEADENYLYLTRANSFERASE (Burkholderiapseudomallei) | 5 / 11 | LEU A 58VAL A 35TYR A 6PRO A 12LEU A 13 | NoneNoneCOD A 201 (-4.7A)NoneNone | 1.23A | 1klmA-3pxuA:undetectable | 1klmA-3pxuA:14.26 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2OZ7_A_CA4A1_2 (ANDROGEN RECEPTOR) |
3uf6 | LMO1369 PROTEIN (Listeriamonocytogenes) | 4 / 6 | LEU A 285MET A 136MET A 98LEU A 114 | NoneCOD A 289 (-4.7A)NoneNone | 1.32A | 2oz7A-3uf6A:undetectable | 2oz7A-3uf6A:17.93 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2XFH_A_CL6A1413_1 (ERYTHROMYCIN B/DC-12 HYDROXYLASE) |
2grj | DEPHOSPHO-COA KINASE (Thermotogamaritima) | 4 / 6 | HIS A 84GLN A 145ALA A 106THR A 6 | COD A 201 (-3.7A)COD A 201 (-3.5A)COD A 201 ( 3.8A)None | 1.04A | 2xfhA-2grjA:undetectable | 2xfhA-2grjA:19.40 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3LSL_A_PZIA802_0 (GLUTAMATE RECEPTOR 2) |
3uf6 | LMO1369 PROTEIN (Listeriamonocytogenes) | 3 / 3 | ASP A 270ASN A 269SER A 254 | COD A 289 ( 3.8A)COD A 289 ( 4.4A)COD A 289 (-3.5A) | 0.96A | 3lslA-3uf6A:2.23lslD-3uf6A:undetectable | 3lslA-3uf6A:21.223lslD-3uf6A:21.22 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3LSL_D_PZID802_0 (GLUTAMATE RECEPTOR 2) |
3uf6 | LMO1369 PROTEIN (Listeriamonocytogenes) | 3 / 3 | SER A 254ASP A 270ASN A 269 | COD A 289 (-3.5A)COD A 289 ( 3.8A)COD A 289 ( 4.4A) | 0.98A | 3lslA-3uf6A:2.23lslD-3uf6A:undetectable | 3lslA-3uf6A:21.223lslD-3uf6A:21.22 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4EAT_A_BEZA1000_0 (BENZOATE-COENZYME ALIGASE) |
2grj | DEPHOSPHO-COA KINASE (Thermotogamaritima) | 4 / 7 | GLY A 7ILE A 9GLY A 10ILE A 131 | NoneCOD A 201 (-3.8A)ADP A 200 (-3.5A)None | 0.67A | 4eatA-2grjA:undetectable | 4eatA-2grjA:15.55 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5AXD_C_RBVC502_2 (ADENOSYLHOMOCYSTEINASE) |
2grj | DEPHOSPHO-COA KINASE (Thermotogamaritima) | 3 / 3 | THR A 98HIS A 84LEU A 114 | NoneCOD A 201 (-3.7A)None | 0.88A | 5axdC-2grjA:undetectable | 5axdC-2grjA:19.68 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5CU6_A_ACTA403_0 (CASEIN KINASE IISUBUNIT ALPHA) |
3uf6 | LMO1369 PROTEIN (Listeriamonocytogenes) | 4 / 6 | TYR A 241ILE A 122VAL A 245ALA A 250 | COD A 289 (-4.1A)NoneNoneNone | 0.78A | 5cu6A-3uf6A:undetectable | 5cu6A-3uf6A:23.01 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5OSR_A_ACTA402_0 (CASEIN KINASE IISUBUNIT ALPHA) |
3uf6 | LMO1369 PROTEIN (Listeriamonocytogenes) | 4 / 7 | TYR A 241ILE A 122VAL A 245ALA A 250 | COD A 289 (-4.1A)NoneNoneNone | 0.78A | 5osrA-3uf6A:undetectable | 5osrA-3uf6A:21.49 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 6JMJ_A_ASCA201_0 (PHOSPHOPANTETHEINEADENYLYLTRANSFERASE) |
3pxu | PHOSPHOPANTETHEINEADENYLYLTRANSFERASE (Burkholderiapseudomallei) | 4 / 5 | GLY A 8THR A 9HIS A 17SER A 127 | COD A 201 (-3.1A)COD A 201 (-3.6A)COD A 201 (-4.3A)SO4 A 205 (-3.0A) | 0.74A | 6jmjA-3pxuA:25.4 | 6jmjA-3pxuA:52.98 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 6JNH_A_ASCA201_0 (PHOSPHOPANTETHEINEADENYLYLTRANSFERASE) |
3pxu | PHOSPHOPANTETHEINEADENYLYLTRANSFERASE (Burkholderiapseudomallei) | 5 / 7 | GLY A 8THR A 9PHE A 10HIS A 17SER A 127 | COD A 201 (-3.1A)COD A 201 (-3.6A)COD A 201 (-4.5A)COD A 201 (-4.3A)SO4 A 205 (-3.0A) | 0.75A | 6jnhA-3pxuA:25.6 | 6jnhA-3pxuA:52.98 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 6JOG_A_ASCA201_0 (PHOSPHOPANTETHEINEADENYLYLTRANSFERASE) |
3pxu | PHOSPHOPANTETHEINEADENYLYLTRANSFERASE (Burkholderiapseudomallei) | 4 / 6 | GLY A 8THR A 9HIS A 17SER A 127 | COD A 201 (-3.1A)COD A 201 (-3.6A)COD A 201 (-4.3A)SO4 A 205 (-3.0A) | 0.79A | 6jogA-3pxuA:25.4 | 6jogA-3pxuA:52.98 |