SIMILAR PATTERN OF AMINO ACIDS MAPPED TO 'COB'

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)	View	Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1AEG_A_4APA296_1 (CYTOCHROME C PEROXIDASE)	4jgi	PUTATIVE UNCHARACTERIZED PROTEIN (Desulfitobacteri um hafniense)	4 / 8	HIS A 102 GLY A 179 LEU A 150 ASP A 100	COB  A 301 (-3.7A) COB  A 301 (-3.2A) COB  A 301 (-4.3A) COB  A 301 (-3.5A)	0.71A	1aegA-4jgiA: undetectable	1aegA-4jgiA: 20.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1IKV_A_EFZA2000_1 (POL POLYPROTEIN)	1bmt	METHIONINE SYNTHASE (Escherichia coli)	5 / 9	LEU A 831 VAL A 766 TYR A 775 GLY A 767 LEU A 800	COB  A 122 (-4.4A) COB  A 122 ( 4.6A) None None None	1.28A	1ikvA-1bmtA: 1.7	1ikvA-1bmtA: 18.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1PBC_A_BHAA396_0 (P-HYDROXYBENZOATE HYDROXYLASE)	1bmt	METHIONINE SYNTHASE (Escherichia coli)	5 / 10	GLY A 865 VAL A 866 LEU A 831 TYR A 775 ALA A 869	None None COB  A 122 (-4.4A) None None	1.25A	1pbcA-1bmtA: 3.3	1pbcA-1bmtA: 20.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3EKW_B_DR7B100_2 (PROTEASE)	4jgi	PUTATIVE UNCHARACTERIZED PROTEIN (Desulfitobacteri um hafniense)	5 / 12	ASP A 193 ILE A 143 VAL A 144 GLY A 145 ALA A 199	None None None COB  A 301 (-3.6A) COB  A 301 (-3.4A)	0.97A	3ekwB-4jgiA: undetectable	3ekwB-4jgiA: 18.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3NV6_A_CAMA422_0 (CYTOCHROME P450)	1bmt	METHIONINE SYNTHASE (Escherichia coli)	3 / 3	GLY A 833 ILE A 765 VAL A 766	COB  A 122 ( 3.8A) COB  A 122 (-4.0A) COB  A 122 ( 4.6A)	0.47A	3nv6A-1bmtA: 0.0	3nv6A-1bmtA: 22.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4DO3_A_0LAA602_1 (FATTY-ACID AMIDE HYDROLASE 1)	1bmt	METHIONINE SYNTHASE (Escherichia coli)	4 / 5	LEU A 870 LEU A 831 MET A 749 THR A 863	None COB  A 122 (-4.4A) None COB  A 122 (-3.4A)	1.45A	4do3A-1bmtA: 1.0	4do3A-1bmtA: 16.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4RZV_B_032B801_2 (SERINE/THREONINE-PRO TEIN KINASE B-RAF)	1bmt	METHIONINE SYNTHASE (Escherichia coli)	4 / 5	ILE A 832 SER A 838 HIS A 841 ASP A 757	None None None COB  A 122 (-4.1A)	1.20A	4rzvB-1bmtA: undetectable	4rzvB-1bmtA: 22.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5ENT_C_MIYC901_1 (MULTIDRUG EFFLUX PUMP SUBUNIT ACRB,MULTIDRUG EFFLUX PUMP SUBUNIT ACRB)	4jgi	PUTATIVE UNCHARACTERIZED PROTEIN (Desulfitobacteri um hafniense)	5 / 9	PHE A 195 GLY A 178 SER A 147 ILE A 176 ALA A 192	None COB  A 301 (-3.6A) COB  A 301 (-2.7A) COB  A 301 ( 4.2A) None	1.30A	5entC-4jgiA: undetectable	5entC-4jgiA: 18.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5XIP_C_HFGC1003_0 (PROLYL-TRNA SYNTHETASE, PUTATIVE)	4jgi	PUTATIVE UNCHARACTERIZED PROTEIN (Desulfitobacteri um hafniense)	5 / 12	LEU A 173 VAL A 136 PRO A 141 PHE A 109 GLY A 117	None None None COB  A 301 (-3.6A) None	1.21A	5xipC-4jgiA: 6.8	5xipC-4jgiA: 19.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5XIQ_A_HFGA1002_0 (PROLYL-TRNA SYNTHETASE (PRORS))	4jgi	PUTATIVE UNCHARACTERIZED PROTEIN (Desulfitobacteri um hafniense)	5 / 12	LEU A 173 VAL A 136 PRO A 141 PHE A 109 GLY A 117	None None None COB  A 301 (-3.6A) None	1.17A	5xiqA-4jgiA: 7.1	5xiqA-4jgiA: 18.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5XIQ_D_HFGD1002_0 (PROLYL-TRNA SYNTHETASE (PRORS))	4jgi	PUTATIVE UNCHARACTERIZED PROTEIN (Desulfitobacteri um hafniense)	5 / 12	LEU A 173 VAL A 136 PRO A 141 PHE A 109 GLY A 117	None None None COB  A 301 (-3.6A) None	1.25A	5xiqD-4jgiA: 7.1	5xiqD-4jgiA: 18.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5ZRF_D_EVPD101_1 ()	4jgi	PUTATIVE UNCHARACTERIZED PROTEIN (Desulfitobacteri um hafniense)	4 / 5	GLY A 202 ASP A 201 ARG A 208 GLN A  43	COB  A 301 ( 4.1A) None None None	1.21A	5zrfB-4jgiA: 4.7	5zrfB-4jgiA: 15.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6BSG_A_EFZA601_1 (REVERSE TRANSCRIPTASE P66 SUBUNIT)	1bmt	METHIONINE SYNTHASE (Escherichia coli)	5 / 10	LEU A 831 VAL A 766 TYR A 775 GLY A 767 LEU A 800	COB  A 122 (-4.4A) COB  A 122 ( 4.6A) None None None	1.38A	6bsgA-1bmtA: 0.0	6bsgA-1bmtA: 19.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6BXN_B_SAMB901_0 (DIPHTHAMIDE BIOSYNTHESIS ENZYME DPH2)	4jgi	PUTATIVE UNCHARACTERIZED PROTEIN (Desulfitobacteri um hafniense)	5 / 12	PHE A 195 LEU A 146 GLY A 145 ILE A 205 ASP A 201	None None COB  A 301 (-3.6A) None None	1.24A	6bxnB-4jgiA: 5.6	6bxnB-4jgiA: 21.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6BZO_C_FI8C1201_0 (DNA-DIRECTED RNA POLYMERASE SUBUNIT BETA)	4jgi	PUTATIVE UNCHARACTERIZED PROTEIN (Desulfitobacteri um hafniense)	5 / 12	ILE A 108 THR A  96 VAL A  97 VAL A 127 VAL A 182	COB  A 301 ( 4.1A) None None None None	1.21A	6bzoC-4jgiA: undetectable	6bzoC-4jgiA: 11.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6F8C_A_STRA502_1 (CYTOCHROME P450 CYP260A1)	1bmt	METHIONINE SYNTHASE (Escherichia coli)	4 / 6	ALA A 752 GLY A 834 THR A 837 ILE A 846	None COB  A 122 (-3.6A) None None	0.89A	6f8cA-1bmtA: 0.0	6f8cA-1bmtA: 14.83