SIMILAR PATTERN OF AMINO ACIDS MAPPED TO 'CNB'


List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1NNF_A_EDTA400_0
(IRON-UTILIZATION
PERIPLASMIC PROTEIN)		 1r1n FERRIC-IRON BINDING
PROTEIN
(Neisseria
gonorrhoeae) 		8 / 11 GLU A  57
ARG A 101
SER A 139
ALA A 141
LYS A 174
ASN A 175
ASN A 193
TYR A 195
 None
None
CNB  A 400 ( 3.8A)
CNB  A 400 ( 4.7A)
CNB  A 400 ( 3.8A)
CNB  A 400 (-3.9A)
CNB  A 400 (-4.6A)
CNB  A 400 (-4.8A)
 0.89A 1nnfA-1r1nA:
47.6		 1nnfA-1r1nA:
70.87
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1NNF_A_EDTA400_0
(IRON-UTILIZATION
PERIPLASMIC PROTEIN)		 1r1n FERRIC-IRON BINDING
PROTEIN
(Neisseria
gonorrhoeae) 		8 / 11 GLU A  57
SER A 139
ALA A 141
LYS A 174
ASN A 175
ASN A 193
TYR A 195
TYR A 196
 None
CNB  A 400 ( 3.8A)
CNB  A 400 ( 4.7A)
CNB  A 400 ( 3.8A)
CNB  A 400 (-3.9A)
CNB  A 400 (-4.6A)
CNB  A 400 (-4.8A)
CNB  A 400 (-3.7A)
 0.78A 1nnfA-1r1nA:
47.6		 1nnfA-1r1nA:
70.87
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1NNF_A_EDTA400_0
(IRON-UTILIZATION
PERIPLASMIC PROTEIN)		 1r1n FERRIC-IRON BINDING
PROTEIN
(Neisseria
gonorrhoeae) 		5 / 11 GLU A 144
LYS A 174
ASN A 175
ASN A 193
TYR A 196
 None
CNB  A 400 ( 3.8A)
CNB  A 400 (-3.9A)
CNB  A 400 (-4.6A)
CNB  A 400 (-3.7A)
 1.35A 1nnfA-1r1nA:
47.6		 1nnfA-1r1nA:
70.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUF_B_SUEB1201_3
(NS3 PROTEASE, NS4A
PROTEIN)		 1r1n FERRIC-IRON BINDING
PROTEIN
(Neisseria
gonorrhoeae) 		4 / 5 SER A 228
ARG A 101
TYR A 195
VAL A 225
 None
None
CNB  A 400 (-4.8A)
None
 1.36A 3sufC-1r1nA:
undetectable		 3sufC-1r1nA:
22.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TJ7_C_ACTC610_0
(GBAA_1210 PROTEIN)		 1r1n FERRIC-IRON BINDING
PROTEIN
(Neisseria
gonorrhoeae) 		3 / 3 ASN A 175
ALA A 141
ARG A 103
 CNB  A 400 (-3.9A)
CNB  A 400 ( 4.7A)
None
 0.90A 3tj7C-1r1nA:
undetectable
3tj7D-1r1nA:
undetectable		 3tj7C-1r1nA:
18.91
3tj7D-1r1nA:
18.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TJ7_C_ACTC610_0
(GBAA_1210 PROTEIN)		 1r1n FERRIC-IRON BINDING
PROTEIN
(Neisseria
gonorrhoeae) 		3 / 3 ASN A 193
ALA A 141
ARG A 103
 CNB  A 400 (-4.6A)
CNB  A 400 ( 4.7A)
None
 0.74A 3tj7C-1r1nA:
undetectable
3tj7D-1r1nA:
undetectable		 3tj7C-1r1nA:
18.91
3tj7D-1r1nA:
18.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IKT_B_TLFB601_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 1r1n FERRIC-IRON BINDING
PROTEIN
(Neisseria
gonorrhoeae) 		3 / 3 TYR A 196
TYR A  55
SER A 228
 CNB  A 400 (-3.7A)
None
None
 0.90A 5iktB-1r1nA:
0.0		 5iktB-1r1nA:
21.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0R_A_SAMA501_1
(PEPTIDE
N-METHYLTRANSFERASE)		 1r1n FERRIC-IRON BINDING
PROTEIN
(Neisseria
gonorrhoeae) 		4 / 4 SER A 139
ALA A 141
GLN A  58
THR A 226
 CNB  A 400 ( 3.8A)
CNB  A 400 ( 4.7A)
None
None
 1.17A 5n0rA-1r1nA:
undetectable		 5n0rA-1r1nA:
21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0S_A_SAMA501_1
(PEPTIDE
N-METHYLTRANSFERASE)		 1r1n FERRIC-IRON BINDING
PROTEIN
(Neisseria
gonorrhoeae) 		4 / 4 SER A 139
ALA A 141
GLN A  58
THR A 226
 CNB  A 400 ( 3.8A)
CNB  A 400 ( 4.7A)
None
None
 1.20A 5n0sA-1r1nA:
undetectable		 5n0sA-1r1nA:
22.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0T_A_SAMA501_1
(PEPTIDE
N-METHYLTRANSFERASE)		 1r1n FERRIC-IRON BINDING
PROTEIN
(Neisseria
gonorrhoeae) 		4 / 5 SER A 139
ALA A 141
GLN A  58
THR A 226
 CNB  A 400 ( 3.8A)
CNB  A 400 ( 4.7A)
None
None
 1.18A 5n0tA-1r1nA:
undetectable		 5n0tA-1r1nA:
21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0W_A_SAMA501_1
(PEPTIDE
N-METHYLTRANSFERASE)		 1r1n FERRIC-IRON BINDING
PROTEIN
(Neisseria
gonorrhoeae) 		4 / 4 SER A 139
ALA A 141
GLN A  58
THR A 226
 CNB  A 400 ( 3.8A)
CNB  A 400 ( 4.7A)
None
None
 1.20A 5n0wA-1r1nA:
undetectable		 5n0wA-1r1nA:
21.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0W_B_SAMB501_1
(PEPTIDE
N-METHYLTRANSFERASE)		 1r1n FERRIC-IRON BINDING
PROTEIN
(Neisseria
gonorrhoeae) 		4 / 5 SER A 139
ALA A 141
GLN A  58
THR A 226
 CNB  A 400 ( 3.8A)
CNB  A 400 ( 4.7A)
None
None
 1.20A 5n0wB-1r1nA:
undetectable		 5n0wB-1r1nA:
21.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0X_A_SAMA501_1
(PEPTIDE
N-METHYLTRANSFERASE)		 1r1n FERRIC-IRON BINDING
PROTEIN
(Neisseria
gonorrhoeae) 		4 / 4 SER A 139
ALA A 141
GLN A  58
THR A 226
 CNB  A 400 ( 3.8A)
CNB  A 400 ( 4.7A)
None
None
 1.19A 5n0xA-1r1nA:
undetectable		 5n0xA-1r1nA:
21.53