SIMILAR PATTERN OF AMINO ACIDS MAPPED TO 'CMU'
DrReposER ID / Desc. | Hit PDBID |
Hit Macromolecule |
Res. Matches |
Interface | HETATM | RMSD | Dali Z-score |
Seq. Identity (%) |
View | Dock | |
---|---|---|---|---|---|---|---|---|---|---|---|
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2WA2_A_SAMA1248_0 (NON-STRUCTURALPROTEIN 5) |
1uou | THYMIDINEPHOSPHORYLASE (Homosapiens) | 5 / 12 | GLY A 405GLY A 149GLY A 147VAL A 208THR A 207 | NoneNoneCMU A1481 ( 4.9A)NoneNone | 0.98A | 2wa2A-1uouA:undetectable | 2wa2A-1uouA:20.97 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3VAQ_B_ADNB401_2 (PUTATIVE ADENOSINEKINASE) |
1uou | THYMIDINEPHOSPHORYLASE (Homosapiens) | 4 / 4 | LEU A 155GLY A 153MET A 142PHE A 164 | NoneCMU A1481 ( 4.1A)NoneNone | 1.21A | 3vaqB-1uouA:1.9 | 3vaqB-1uouA:21.93 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4LHM_A_AZZA510_1 (THYMIDINEPHOSPHORYLASE) |
1uou | THYMIDINEPHOSPHORYLASE (Homosapiens) | 6 / 11 | ARG A 202VAL A 208ILE A 214SER A 217LYS A 221LEU A 251 | CMU A1481 (-2.8A)NoneCMU A1481 (-3.9A)CMU A1481 (-2.7A)CMU A1481 (-2.6A)None | 0.32A | 4lhmA-1uouA:49.0 | 4lhmA-1uouA:38.67 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4LHM_A_AZZA510_1 (THYMIDINEPHOSPHORYLASE) |
1uou | THYMIDINEPHOSPHORYLASE (Homosapiens) | 5 / 11 | THR A 118TYR A 199SER A 217LYS A 221LEU A 251 | NoneCMU A1481 (-4.7A)CMU A1481 (-2.7A)CMU A1481 (-2.6A)None | 1.07A | 4lhmA-1uouA:49.0 | 4lhmA-1uouA:38.67 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4LHM_A_AZZA510_1 (THYMIDINEPHOSPHORYLASE) |
1uou | THYMIDINEPHOSPHORYLASE (Homosapiens) | 6 / 11 | TYR A 199ARG A 202ILE A 214SER A 217LYS A 221LEU A 251 | CMU A1481 (-4.7A)CMU A1481 (-2.8A)CMU A1481 (-3.9A)CMU A1481 (-2.7A)CMU A1481 (-2.6A)None | 0.66A | 4lhmA-1uouA:49.0 | 4lhmA-1uouA:38.67 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5YOD_H_BEZH201_0 (NS3 PROTEASE) |
1uou | THYMIDINEPHOSPHORYLASE (Homosapiens) | 4 / 5 | HIS A 116SER A 144GLY A 145TYR A 199 | CMU A1481 (-4.3A)NoneNoneCMU A1481 (-4.7A) | 1.45A | 5yodH-1uouA:undetectable | 5yodH-1uouA:17.61 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ZHM_B_SAMB301_1 (TRNA(GUANINE-N(1)-)-METHYLTRANSFERASE) |
1uou | THYMIDINEPHOSPHORYLASE (Homosapiens) | 5 / 12 | GLY A 147GLY A 149SER A 117VAL A 121GLY A 153 | CMU A1481 ( 4.9A)NoneCMU A1481 (-4.3A)NoneCMU A1481 ( 4.1A) | 0.86A | 5zhmB-1uouA:2.2 | 5zhmB-1uouA:22.68 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6EU9_B_REAB601_1 (RETINOIC ACIDRECEPTOR) |
1uou | THYMIDINEPHOSPHORYLASE (Homosapiens) | 5 / 10 | LEU A 395LEU A 423GLY A 119GLY A 278VAL A 281 | NoneNoneCMU A1481 ( 3.8A)NoneNone | 1.21A | 6eu9B-1uouA:0.0 | 6eu9B-1uouA:8.86 |