SIMILAR PATTERN OF AMINO ACIDS MAPPED TO 'CMH'


List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OXT_B_SAMB300_1
(NUCLEOSIDE-2'-O-METH
YLTRANSFERASE)		 4aca TRANSLATION
ELONGATION FACTOR
SELB
(Methanococcus
maripaludis) 		4 / 5 SER A 286
GLY A 372
HIS A 103
ASP A  71
 CMH  A 371 ( 4.5A)
CMH  A 371 ( 2.4A)
None
None
 0.85A 2oxtB-4acaA:
undetectable		 2oxtB-4acaA:
19.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EQM_A_ASDA601_1
(CYTOCHROME P450 19A1)		 4ct3 ORF30/ORF32
(Staphylococcus
virus
K) 		5 / 10 ILE A 159
ILE A 118
THR A  72
VAL A  70
LEU A  65
 None
CMH  A1166 (-4.7A)
None
None
None
 1.26A 3eqmA-4ct3A:
undetectable		 3eqmA-4ct3A:
12.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OCT_A_1N1A663_2
(TYROSINE-PROTEIN
KINASE BTK)		 4aca TRANSLATION
ELONGATION FACTOR
SELB
(Methanococcus
maripaludis) 		4 / 5 PHE A 342
ILE A 387
MET A 297
PHE A 315
 CMH  A 340 ( 4.2A)
None
None
CMH  A 340 ( 4.6A)
 1.35A 3octA-4acaA:
undetectable		 3octA-4acaA:
18.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S79_A_ASDA601_1
(CYTOCHROME P450 19A1)		 4ct3 ORF30/ORF32
(Staphylococcus
virus
K) 		5 / 12 ILE A 159
ILE A 118
THR A  72
VAL A  70
LEU A  65
 None
CMH  A1166 (-4.7A)
None
None
None
 1.26A 3s79A-4ct3A:
undetectable		 3s79A-4ct3A:
12.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W67_C_VIVC301_0
(ALPHA-TOCOPHEROL
TRANSFER PROTEIN)		 4aca TRANSLATION
ELONGATION FACTOR
SELB
(Methanococcus
maripaludis) 		5 / 12 ILE A 387
TRP A 467
ALA A 281
LEU A 301
VAL A 356
 None
None
CMH  A 340 ( 4.3A)
None
None
 0.98A 3w67C-4acaA:
1.6		 3w67C-4acaA:
20.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A81_A_DXCA1161_0
(MAJOR POLLEN
ALLERGEN BET V 1-A)		 4aca TRANSLATION
ELONGATION FACTOR
SELB
(Methanococcus
maripaludis) 		5 / 12 ILE A 223
ILE A 252
VAL A 229
MET A 188
LEU A 190
 None
None
None
None
CMH  A 264 ( 4.1A)
 1.21A 4a81A-4acaA:
undetectable		 4a81A-4acaA:
17.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KQ8_A_ASDA602_1
(CYTOCHROME P450 19A1)		 4ct3 ORF30/ORF32
(Staphylococcus
virus
K) 		5 / 10 ILE A 159
ILE A 118
THR A  72
VAL A  70
LEU A  65
 None
CMH  A1166 (-4.7A)
None
None
None
 1.21A 4kq8A-4ct3A:
undetectable		 4kq8A-4ct3A:
13.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JKV_A_ASDA602_1
(AROMATASE)		 4ct3 ORF30/ORF32
(Staphylococcus
virus
K) 		5 / 12 ILE A 159
ILE A 118
THR A  72
VAL A  70
LEU A  65
 None
CMH  A1166 (-4.7A)
None
None
None
 1.24A 5jkvA-4ct3A:
undetectable		 5jkvA-4ct3A:
12.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JKW_A_TESA601_1
(AROMATASE)		 4ct3 ORF30/ORF32
(Staphylococcus
virus
K) 		5 / 11 ILE A 159
ILE A 118
THR A  72
VAL A  70
LEU A  65
 None
CMH  A1166 (-4.7A)
None
None
None
 1.21A 5jkwA-4ct3A:
undetectable		 5jkwA-4ct3A:
12.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JL6_A_ASDA601_1
(AROMATASE)		 4ct3 ORF30/ORF32
(Staphylococcus
virus
K) 		5 / 9 ILE A 159
ILE A 118
THR A  72
VAL A  70
LEU A  65
 None
CMH  A1166 (-4.7A)
None
None
None
 1.20A 5jl6A-4ct3A:
0.0		 5jl6A-4ct3A:
12.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JL7_A_ASDA601_1
(AROMATASE)		 4ct3 ORF30/ORF32
(Staphylococcus
virus
K) 		5 / 10 ILE A 159
ILE A 118
THR A  72
VAL A  70
LEU A  65
 None
CMH  A1166 (-4.7A)
None
None
None
 1.25A 5jl7A-4ct3A:
undetectable		 5jl7A-4ct3A:
12.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JL9_A_ASDA601_1
(AROMATASE)		 4ct3 ORF30/ORF32
(Staphylococcus
virus
K) 		5 / 9 ILE A 159
ILE A 118
THR A  72
VAL A  70
LEU A  65
 None
CMH  A1166 (-4.7A)
None
None
None
 1.25A 5jl9A-4ct3A:
undetectable		 5jl9A-4ct3A:
12.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EBP_A_DAHA123_0
(RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE,
BETA SUBUNIT)		 4ct3 ORF30/ORF32
(Staphylococcus
virus
K) 		5 / 9 LEU A 155
GLY A 116
ILE A 118
PHE A 130
ILE A 132
 None
None
CMH  A1166 (-4.7A)
None
None
 1.34A 6ebpA-4ct3A:
undetectable		 6ebpA-4ct3A:
19.39