SIMILAR PATTERN OF AMINO ACIDS MAPPED TO 'CLR'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

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	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1DYI_A_FOLA161_0 (DIHYDROFOLATE REDUCTASE)	4dkl	MU-TYPE OPIOID RECEPTOR, LYSOZYME CHIMERA (Mus musculus; Escherichia virus T4)	5 / 12	ILE A 242 ALA A 240 PHE A 237 THR A 294 ILE A 298	None None None CLR A 614 ( 4.0A) CLR A 614 ( 4.1A)	1.09A	1dyiA-4dklA: undetectable	1dyiA-4dklA: 16.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1EQG_B_IBPB1701_1 (PROSTAGLANDIN H2 SYNTHASE-1)	4xnu	INTEGRAL MEMBRANE PROTEIN-DOPAMINE TRANSPORTER (Drosophila melanogaster)	5 / 11	SER A 349 LEU A 73 ILE A 351 ALA A 354 SER A 356	None None CLR A 604 (-4.3A) None CL A 603 (-2.9A)	1.15A	1eqgB-4xnuA: undetectable	1eqgB-4xnuA: 21.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1FM6_A_9CRA501_1 (RETINOIC ACID RECEPTOR RXR-ALPHA)	3am6	RHODOPSIN-2 (Acetabularia acetabulum)	5 / 12	ILE A 44 ALA A 47 VAL A 95 CYH A 218 LEU A 219	None None None None CLR A 401 ( 4.6A)	0.94A	1fm6A-3am6A: undetectable	1fm6A-3am6A: 21.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1FM9_A_9CRA201_1 (RETINOIC ACID RECEPTOR RXR-ALPHA)	3am6	RHODOPSIN-2 (Acetabularia acetabulum)	5 / 12	ILE A 44 ALA A 47 VAL A 95 CYH A 218 LEU A 219	None None None None CLR A 401 ( 4.6A)	0.95A	1fm9A-3am6A: undetectable	1fm9A-3am6A: 21.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1GTI_F_CCSF47_0 (GLUTATHIONE S-TRANSFERASE)	4bqu	JAPANIN (Rhipicephalus appendiculatus)	4 / 5	THR A 113 LEU A 104 LYS A 89 TYR A 92	None CLR A 575 ( 4.7A) None CLR A 575 ( 3.4A)	1.29A	1gtiF-4bquA: undetectable	1gtiF-4bquA: 20.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1JIP_A_KTNA801_1 (CYTOCHROME P450 107A1)	4xnu	INTEGRAL MEMBRANE PROTEIN-DOPAMINE TRANSPORTER (Drosophila melanogaster)	5 / 12	PHE A 53 ALA A 359 LEU A 279 LEU A 414 LEU A 276	CL A 603 ( 4.8A) None None None CLR A 604 ( 4.7A)	1.44A	1jipA-4xnuA: 0.3	1jipA-4xnuA: 23.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1K74_A_9CRA463_1 (RETINOIC ACID RECEPTOR RXR-ALPHA)	3am6	RHODOPSIN-2 (Acetabularia acetabulum)	5 / 12	ILE A 44 ALA A 47 VAL A 95 CYH A 218 LEU A 219	None None None None CLR A 401 ( 4.6A)	0.95A	1k74A-3am6A: undetectable	1k74A-3am6A: 21.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1TDR_A_MTXA170_1 (TELLUROMETHIONYL DIHYDROFOLATE REDUCTASE)	4dkl	MU-TYPE OPIOID RECEPTOR, LYSOZYME CHIMERA (Escherichia virus T4; Mus musculus)	5 / 12	ILE A 242 ALA A 240 PHE A 237 THR A 294 ILE A 298	None None None CLR A 614 ( 4.0A) CLR A 614 ( 4.1A)	1.06A	1tdrA-4dklA: undetectable	1tdrA-4dklA: 16.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1XDK_A_9CRA500_1 (RETINOIC ACID RECEPTOR RXR-ALPHA)	3am6	RHODOPSIN-2 (Acetabularia acetabulum)	5 / 12	ILE A 44 ALA A 47 VAL A 95 CYH A 218 LEU A 219	None None None None CLR A 401 ( 4.6A)	1.01A	1xdkA-3am6A: undetectable	1xdkA-3am6A: 21.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1XDK_E_9CRE1500_1 (RETINOIC ACID RECEPTOR RXR-ALPHA)	3am6	RHODOPSIN-2 (Acetabularia acetabulum)	5 / 12	ILE A 44 ALA A 47 VAL A 95 CYH A 218 LEU A 219	None None None None CLR A 401 ( 4.6A)	1.01A	1xdkE-3am6A: undetectable	1xdkE-3am6A: 21.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1XIU_A_9CRA201_1 (RXR-LIKE PROTEIN)	3am6	RHODOPSIN-2 (Acetabularia acetabulum)	5 / 12	ILE A 44 ALA A 47 VAL A 95 CYH A 218 LEU A 219	None None None None CLR A 401 ( 4.6A)	0.88A	1xiuA-3am6A: undetectable	1xiuA-3am6A: 21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1XIU_B_9CRB202_1 (RXR-LIKE PROTEIN)	3am6	RHODOPSIN-2 (Acetabularia acetabulum)	5 / 12	ILE A 44 ALA A 47 VAL A 95 CYH A 218 LEU A 219	None None None None CLR A 401 ( 4.6A)	0.90A	1xiuB-3am6A: undetectable	1xiuB-3am6A: 21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1XLS_A_9CRA801_1 (RETINOIC ACID RECEPTOR RXR-ALPHA)	3am6	RHODOPSIN-2 (Acetabularia acetabulum)	5 / 12	ILE A 44 ALA A 47 VAL A 95 CYH A 218 LEU A 219	None None None None CLR A 401 ( 4.6A)	0.94A	1xlsA-3am6A: undetectable	1xlsA-3am6A: 21.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1XLS_B_9CRB802_1 (RETINOIC ACID RECEPTOR RXR-ALPHA)	3am6	RHODOPSIN-2 (Acetabularia acetabulum)	5 / 12	ILE A 44 ALA A 47 VAL A 95 CYH A 218 LEU A 219	None None None None CLR A 401 ( 4.6A)	0.93A	1xlsB-3am6A: undetectable	1xlsB-3am6A: 21.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1XLS_C_9CRC803_1 (RETINOIC ACID RECEPTOR RXR-ALPHA)	3am6	RHODOPSIN-2 (Acetabularia acetabulum)	5 / 12	ILE A 44 ALA A 47 VAL A 95 CYH A 218 LEU A 219	None None None None CLR A 401 ( 4.6A)	0.93A	1xlsC-3am6A: undetectable	1xlsC-3am6A: 21.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1XLS_D_9CRD804_1 (RETINOIC ACID RECEPTOR RXR-ALPHA)	3am6	RHODOPSIN-2 (Acetabularia acetabulum)	5 / 12	ILE A 44 ALA A 47 VAL A 95 CYH A 218 LEU A 219	None None None None CLR A 401 ( 4.6A)	0.94A	1xlsD-3am6A: undetectable	1xlsD-3am6A: 21.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1YA4_C_CTXC1383_1 (CES1 PROTEIN)	6aqf	ADENOSINE RECEPTOR A2A,SOLUBLE CYTOCHROME B562,ADENOSINE RECEPTOR A2A (Escherichia coli; Homo sapiens)	4 / 5	TRP A 246 PRO A 248 LEU A 244 GLY A 240	None CLR A1202 (-4.1A) None None	1.47A	1ya4C-6aqfA: 0.5	1ya4C-6aqfA: 11.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2AOU_B_CQAB401_0 (HISTAMINE N-METHYLTRANSFERASE)	4or2	SOLUBLE CYTOCHROME B562, METABOTROPIC GLUTAMATE RECEPTOR 1 (Escherichia coli; Homo sapiens)	4 / 7	PRO A1056 ASP A1060 TYR A1105 THR A 653	None None None CLR A1905 (-3.4A)	1.01A	2aouB-4or2A: undetectable	2aouB-4or2A: 19.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2ZZM_A_SAMA401_0 (UNCHARACTERIZED PROTEIN MJ0883)	5lwe	C-C CHEMOKINE RECEPTOR TYPE 9 (Homo sapiens)	5 / 12	LEU A 87 GLY A 65 VAL A 58 LEU A 312 PHE A 308	79K A 401 (-4.3A) OLA A 412 ( 4.1A) None CLR A 417 ( 4.7A) OLA A 402 (-4.1A)	1.01A	2zzmA-5lweA: undetectable	2zzmA-5lweA: 22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3BJW_F_SVRF509_2 (PHOSPHOLIPASE A2)	3jd8	NIEMANN-PICK C1 PROTEIN (Homo sapiens)	4 / 8	ASN A 198 LYS A 196 PRO A 207 PHE A 209	CLR A1325 ( 3.9A) None None None	1.42A	3bjwD-3jd8A: undetectable	3bjwD-3jd8A: 7.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3CR5_X_PNTX95_0 (PROTEIN S100-B)	6aqf	ADENOSINE RECEPTOR A2A,SOLUBLE CYTOCHROME B562,ADENOSINE RECEPTOR A2A (Escherichia coli; Homo sapiens)	3 / 3	CYH A 254 PHE A 257 PHE A 258	CLR A1203 (-4.0A) None None	0.69A	3cr5X-6aqfA: undetectable	3cr5X-6aqfA: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3DZU_A_9CRA7223_1 (RETINOIC ACID RECEPTOR RXR-ALPHA)	3am6	RHODOPSIN-2 (Acetabularia acetabulum)	5 / 12	ILE A 44 ALA A 47 VAL A 95 CYH A 218 LEU A 219	None None None None CLR A 401 ( 4.6A)	1.02A	3dzuA-3am6A: undetectable	3dzuA-3am6A: 18.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3DZY_A_9CRA463_1 (RETINOIC ACID RECEPTOR RXR-ALPHA)	3am6	RHODOPSIN-2 (Acetabularia acetabulum)	5 / 12	ILE A 44 ALA A 47 VAL A 95 CYH A 218 LEU A 219	None None None None CLR A 401 ( 4.6A)	1.04A	3dzyA-3am6A: undetectable	3dzyA-3am6A: 18.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3IEO_A_AMJA300_0 (CARBONIC ANHYDRASE 2)	5sy1	STRA6 (Danio rerio)	4 / 4	ILE A 520 GLN A 417 VAL A 521 PHE A 421	CLR A 701 (-4.9A) None None None	1.47A	3ieoA-5sy1A: undetectable	3ieoA-5sy1A: 17.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3LN1_A_CELA682_1 (PROSTAGLANDIN G/H SYNTHASE 2)	6aqf	ADENOSINE RECEPTOR A2A,SOLUBLE CYTOCHROME B562,ADENOSINE RECEPTOR A2A (Escherichia coli; Homo sapiens)	5 / 12	VAL A 186 LEU A 187 VAL A 239 ALA A 243 LEU A 247	None None None None CLR A1202 ( 4.3A)	1.02A	3ln1A-6aqfA: undetectable	3ln1A-6aqfA: 9.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3LN1_B_CELB682_1 (PROSTAGLANDIN G/H SYNTHASE 2)	6aqf	ADENOSINE RECEPTOR A2A,SOLUBLE CYTOCHROME B562,ADENOSINE RECEPTOR A2A (Escherichia coli; Homo sapiens)	5 / 12	VAL A 186 LEU A 187 VAL A 239 ALA A 243 LEU A 247	None None None None CLR A1202 ( 4.3A)	1.02A	3ln1B-6aqfA: undetectable	3ln1B-6aqfA: 9.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3LN1_C_CELC682_1 (PROSTAGLANDIN G/H SYNTHASE 2)	6aqf	ADENOSINE RECEPTOR A2A,SOLUBLE CYTOCHROME B562,ADENOSINE RECEPTOR A2A (Escherichia coli; Homo sapiens)	5 / 12	VAL A 186 LEU A 187 VAL A 239 ALA A 243 LEU A 247	None None None None CLR A1202 ( 4.3A)	1.02A	3ln1C-6aqfA: undetectable	3ln1C-6aqfA: 9.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3LN1_D_CELD682_1 (PROSTAGLANDIN G/H SYNTHASE 2)	6aqf	ADENOSINE RECEPTOR A2A,SOLUBLE CYTOCHROME B562,ADENOSINE RECEPTOR A2A (Escherichia coli; Homo sapiens)	5 / 12	VAL A 186 LEU A 187 VAL A 239 ALA A 243 LEU A 247	None None None None CLR A1202 ( 4.3A)	1.02A	3ln1D-6aqfA: undetectable	3ln1D-6aqfA: 9.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3OAP_A_9CRA500_1 (RETINOIC ACID RECEPTOR RXR-ALPHA)	3am6	RHODOPSIN-2 (Acetabularia acetabulum)	5 / 12	ILE A 44 ALA A 47 VAL A 95 CYH A 218 LEU A 219	None None None None CLR A 401 ( 4.6A)	0.90A	3oapA-3am6A: undetectable	3oapA-3am6A: 22.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3UVV_B_9CRB501_1 (RETINOIC ACID RECEPTOR RXR-ALPHA)	3am6	RHODOPSIN-2 (Acetabularia acetabulum)	5 / 12	ILE A 44 ALA A 47 VAL A 95 CYH A 218 LEU A 219	None None None None CLR A 401 ( 4.6A)	0.89A	3uvvB-3am6A: undetectable	3uvvB-3am6A: 21.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4A84_A_DXCA1161_0 (MAJOR POLLEN ALLERGEN BET V 1-A)	6d35	SMOOTHENED,SOLUBLE CYTOCHROME B562,SMOOTHENED (Escherichia coli; Xenopus laevis)	5 / 12	PRO A 137 LEU A 140 TYR A 103 VAL A 102 SER A 69	CLR A1201 ( 4.8A) None None None None	1.48A	4a84A-6d35A: undetectable	4a84A-6d35A: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4O8F_B_BRLB501_2 (PEROXISOME PROLIFERATOR-ACTIVAT ED RECEPTOR GAMMA)	4or2	SOLUBLE CYTOCHROME B562, METABOTROPIC GLUTAMATE RECEPTOR 1 (Escherichia coli; Homo sapiens)	4 / 6	ILE A 638 PHE A 639 GLY A 641 ILE A 597	None None None CLR A1902 ( 4.6A)	0.75A	4o8fB-4or2A: undetectable	4o8fB-4or2A: 21.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4O8F_B_BRLB501_2 (PEROXISOME PROLIFERATOR-ACTIVAT ED RECEPTOR GAMMA)	6bhu	MULTIDRUG RESISTANCE-ASSOCIATE D PROTEIN 1 (Bos taurus)	4 / 6	ILE A 969 PHE A1042 GLY A1040 ILE A1090	CLR A1606 ( 4.7A) None None CLR A1606 ( 4.8A)	0.66A	4o8fB-6bhuA: 2.2	4o8fB-6bhuA: 0.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4Q15_A_HFGA803_0 (PROLINE--TRNA LIGASE)	5l7d	SMOOTHENED HOMOLOG,SOLUBLE CYTOCHROME B562,SMOOTHENED HOMOLOG (Escherichia coli; Homo sapiens)	5 / 12	LEU A 146 VAL A 182 PRO A 124 TRP A 119 GLY A 111	None None None None CLR A1203 (-4.0A)	1.31A	4q15A-5l7dA: undetectable	4q15A-5l7dA: 21.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4URO_B_NOVB2000_1 (DNA GYRASE SUBUNIT B)	5l7d	SMOOTHENED HOMOLOG,SOLUBLE CYTOCHROME B562,SMOOTHENED HOMOLOG (Escherichia coli; Homo sapiens)	5 / 12	SER A 96 ASP A 95 ASP A 172 SER A 89 ARG A 173	None CLR A1203 (-3.7A) None None None	1.15A	4uroB-5l7dA: undetectable	4uroB-5l7dA: 16.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4UY8_7_TRP71002_0 (TRYPTOPHANASE)	5sy1	STRA6 (Danio rerio)	4 / 4	ILE A 520 ASN A 519 ILE A 514 VAL A 513	CLR A 701 (-4.9A) CLR A 701 (-3.5A) None None	1.30A	4uy87-5sy1A: undetectable	4uy87-5sy1A: 2.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4X5H_A_FOLA201_0 (DIHYDROFOLATE REDUCTASE)	4dkl	MU-TYPE OPIOID RECEPTOR, LYSOZYME CHIMERA (Mus musculus; Escherichia virus T4)	5 / 12	ILE A 242 ALA A 240 PHE A 237 THR A 294 ILE A 298	None None None CLR A 614 ( 4.0A) CLR A 614 ( 4.1A)	1.12A	4x5hA-4dklA: undetectable	4x5hA-4dklA: 16.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4X5J_A_FOLA201_0 (DIHYDROFOLATE REDUCTASE)	4dkl	MU-TYPE OPIOID RECEPTOR, LYSOZYME CHIMERA (Mus musculus; Escherichia virus T4)	5 / 12	ILE A 242 ALA A 240 PHE A 237 THR A 294 ILE A 298	None None None CLR A 614 ( 4.0A) CLR A 614 ( 4.1A)	1.10A	4x5jA-4dklA: undetectable	4x5jA-4dklA: 16.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4ZVC_A_BEZA301_0 (DIGUANYLATE CYCLASE DOSC)	4xnu	INTEGRAL MEMBRANE PROTEIN-DOPAMINE TRANSPORTER (Drosophila melanogaster)	4 / 8	ILE A 41 LEU A 37 ILE A 351 LEU A 347	None CLR A 604 (-4.4A) CLR A 604 (-4.3A) None	0.81A	4zvcA-4xnuA: 2.1 4zvcB-4xnuA: 2.1	4zvcA-4xnuA: 12.17 4zvcB-4xnuA: 12.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4ZVC_A_BEZA301_0 (DIGUANYLATE CYCLASE DOSC)	4xnu	INTEGRAL MEMBRANE PROTEIN-DOPAMINE TRANSPORTER (Drosophila melanogaster)	4 / 8	ILE A 351 LEU A 347 ILE A 41 LEU A 37	CLR A 604 (-4.3A) None None CLR A 604 (-4.4A)	0.80A	4zvcA-4xnuA: 2.1 4zvcB-4xnuA: 2.1	4zvcA-4xnuA: 12.17 4zvcB-4xnuA: 12.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5E8Q_A_FOLA201_0 (DIHYDROFOLATE REDUCTASE)	4dkl	MU-TYPE OPIOID RECEPTOR, LYSOZYME CHIMERA (Mus musculus; Escherichia virus T4)	5 / 12	ILE A 242 ALA A 240 PHE A 237 THR A 294 ILE A 298	None None None CLR A 614 ( 4.0A) CLR A 614 ( 4.1A)	1.08A	5e8qA-4dklA: undetectable	5e8qA-4dklA: 16.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5E8Q_B_FOLB201_0 (DIHYDROFOLATE REDUCTASE)	4dkl	MU-TYPE OPIOID RECEPTOR, LYSOZYME CHIMERA (Mus musculus; Escherichia virus T4)	5 / 12	ILE A 242 ALA A 240 PHE A 237 THR A 294 ILE A 298	None None None CLR A 614 ( 4.0A) CLR A 614 ( 4.1A)	1.13A	5e8qB-4dklA: undetectable	5e8qB-4dklA: 16.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5IGY_A_ERYA403_1 (MACROLIDE 2'-PHOSPHOTRANSFERAS E II)	5aw4	NA, K-ATPASE ALPHA SUBUNIT NA+,K+-ATPASE BETA SUBUNIT (Squalus acanthias; Squalus acanthias)	4 / 6	TYR A1023 ILE A 998 TYR A1001 TYR B 40	None None None CLR B3001 ( 4.0A)	1.02A	5igyA-5aw4A: undetectable	5igyA-5aw4A: 16.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5IH0_A_ERYA404_1 (MACROLIDE 2'-PHOSPHOTRANSFERAS E II)	5aw4	NA, K-ATPASE ALPHA SUBUNIT NA+,K+-ATPASE BETA SUBUNIT (Squalus acanthias; Squalus acanthias)	4 / 6	TYR A1023 ILE A 998 TYR A1001 TYR B 40	None None None CLR B3001 ( 4.0A)	1.04A	5ih0A-5aw4A: undetectable	5ih0A-5aw4A: 16.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5KIR_B_RCXB601_1 (PROSTAGLANDIN G/H SYNTHASE 2)	6aqf	ADENOSINE RECEPTOR A2A,SOLUBLE CYTOCHROME B562,ADENOSINE RECEPTOR A2A (Escherichia coli; Homo sapiens)	5 / 12	VAL A 186 ALA A 99 VAL A 239 ALA A 243 LEU A 247	None None None None CLR A1202 ( 4.3A)	1.05A	5kirB-6aqfA: undetectable	5kirB-6aqfA: 10.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5UJX_B_FOLB201_0 (DIHYDROFOLATE REDUCTASE)	4dkl	MU-TYPE OPIOID RECEPTOR, LYSOZYME CHIMERA (Mus musculus; Escherichia virus T4)	5 / 12	ILE A 242 ALA A 240 PHE A 237 THR A 294 ILE A 298	None None None CLR A 614 ( 4.0A) CLR A 614 ( 4.1A)	1.15A	5ujxB-4dklA: undetectable	5ujxB-4dklA: 16.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5X19_J_CHDJ101_0 (CYTOCHROME C OXIDASE SUBUNIT 7A1, MITOCHONDRIAL)	5wvr	KLLA0C04147P (Kluyveromyces lactis)	4 / 5	ARG A 861 MET A 862 THR A 863 LEU A 864	None None None CLR A1301 (-4.2A)	1.28A	5x19J-5wvrA: undetectable	5x19J-5wvrA: 8.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5X1B_J_CHDJ101_0 (CYTOCHROME C OXIDASE SUBUNIT 7A1, MITOCHONDRIAL)	5wvr	KLLA0C04147P (Kluyveromyces lactis)	4 / 5	ARG A 861 MET A 862 THR A 863 LEU A 864	None None None CLR A1301 (-4.2A)	1.25A	5x1bJ-5wvrA: undetectable	5x1bJ-5wvrA: 8.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5XIP_C_HFGC1003_0 (PROLYL-TRNA SYNTHETASE, PUTATIVE)	5l7d	SMOOTHENED HOMOLOG,SOLUBLE CYTOCHROME B562,SMOOTHENED HOMOLOG (Escherichia coli; Homo sapiens)	5 / 12	LEU A 146 VAL A 182 PRO A 124 TRP A 119 GLY A 111	None None None None CLR A1203 (-4.0A)	1.26A	5xipC-5l7dA: undetectable	5xipC-5l7dA: 21.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5Z12_B_9CRB501_1 (RETINOIC ACID RECEPTOR RXR-ALPHA)	3am6	RHODOPSIN-2 (Acetabularia acetabulum)	5 / 12	ILE A 44 ALA A 47 VAL A 95 CYH A 218 LEU A 219	None None None None CLR A 401 ( 4.6A)	0.97A	5z12B-3am6A: undetectable	5z12B-3am6A: 15.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5Z12_C_9CRC501_1 (RETINOIC ACID RECEPTOR RXR-ALPHA)	3am6	RHODOPSIN-2 (Acetabularia acetabulum)	5 / 12	ILE A 44 ALA A 47 VAL A 95 CYH A 218 LEU A 219	None None None None CLR A 401 ( 4.6A)	0.91A	5z12C-3am6A: undetectable	5z12C-3am6A: 15.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6EF6_A_BEZA401_0 (AMINOGLYCOSIDE PHOSPHOTRANSFERASE)	3pds	FUSION PROTEIN BETA-2 ADRENERGIC RECEPTOR/LYSOZYME (Homo sapiens; Escherichia virus T4)	5 / 9	LEU A 75 SER A 74 THR A 123 ILE A 127 ILE A 72	None CLR A1202 ( 4.9A) None None None	0.96A	6ef6A-3pdsA: 1.9	6ef6A-3pdsA: 20.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6FGD_A_ACTA821_0 (GEPHYRIN)	5aw4	NA+,K+-ATPASE BETA SUBUNIT (Squalus acanthias)	3 / 3	ARG B 28 PHE B 25 GLY B 27	CLR B3001 (-3.5A) None None	0.74A	6fgdA-5aw4B: undetectable	6fgdA-5aw4B: 20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6NKN_J_CHDJ102_0 (CYTOCHROME C OXIDASE SUBUNIT 7A1, MITOCHONDRIAL)	5wvr	KLLA0C04147P (Kluyveromyces lactis)	4 / 5	ARG A 861 MET A 862 THR A 863 LEU A 864	None None None CLR A1301 (-4.2A)	1.41A	6nknJ-5wvrA: undetectable	6nknJ-5wvrA: 8.76

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1DYI_A_FOLA161_0","DIHYDROFOLATE REDUCTASE","4dkl","MU-TYPE OPIOID RECEPTOR, LYSOZYME CHIMERA","Mus musculus;Escherichia virus T4",5,"ILE A 242;ALA A 240;PHE A 237;THR A 294;ILE A 298","None;None;None;CLR A 614 ( 4.0A);CLR A 614 ( 4.1A)","1.09A","1dyiA-4dklA:undetectable",null],["1EQG_B_IBPB1701_1","PROSTAGLANDIN H2 SYNTHASE-1","4xnu","INTEGRAL MEMBRANE PROTEIN-DOPAMINE TRANSPORTER","Drosophila melanogaster",5,"SER A 349;LEU A  73;ILE A 351;ALA A 354;SER A 356","None;None;CLR A 604 (-4.3A);None; CL A 603 (-2.9A)","1.15A","1eqgB-4xnuA:undetectable","1dyiA-4dklA:16.16"],["1FM6_A_9CRA501_1","RETINOIC ACID RECEPTOR RXR-ALPHA","3am6","RHODOPSIN-2","Acetabularia acetabulum",5,"ILE A  44;ALA A  47;VAL A  95;CYH A 218;LEU A 219","None;None;None;None;CLR A 401 ( 4.6A)","0.94A","1fm6A-3am6A:undetectable","1eqgB-4xnuA:21.76"],["1FM9_A_9CRA201_1","RETINOIC ACID RECEPTOR RXR-ALPHA","3am6","RHODOPSIN-2","Acetabularia acetabulum",5,"ILE A  44;ALA A  47;VAL A  95;CYH A 218;LEU A 219","None;None;None;None;CLR A 401 ( 4.6A)","0.95A","1fm9A-3am6A:undetectable","1fm6A-3am6A:21.85"],["1GTI_F_CCSF47_0","GLUTATHIONE S-TRANSFERASE","4bqu","JAPANIN","Rhipicephalus appendiculatus",4,"THR A 113;LEU A 104;LYS A  89;TYR A  92","None;CLR A 575 ( 4.7A);None;CLR A 575 ( 3.4A)","1.29A","1gtiF-4bquA:undetectable","1fm9A-3am6A:21.85"],["1JIP_A_KTNA801_1","CYTOCHROME P450 107A1","4xnu","INTEGRAL MEMBRANE PROTEIN-DOPAMINE TRANSPORTER","Drosophila melanogaster",5,"PHE A  53;ALA A 359;LEU A 279;LEU A 414;LEU A 276"," CL A 603 ( 4.8A);None;None;None;CLR A 604 ( 4.7A)","1.44A","1jipA-4xnuA:0.3","1gtiF-4bquA:20.26"],["1K74_A_9CRA463_1","RETINOIC ACID RECEPTOR RXR-ALPHA","3am6","RHODOPSIN-2","Acetabularia acetabulum",5,"ILE A  44;ALA A  47;VAL A  95;CYH A 218;LEU A 219","None;None;None;None;CLR A 401 ( 4.6A)","0.95A","1k74A-3am6A:undetectable","1jipA-4xnuA:23.88"],["1TDR_A_MTXA170_1","TELLUROMETHIONYL DIHYDROFOLATE REDUCTASE","4dkl","MU-TYPE OPIOID RECEPTOR, LYSOZYME CHIMERA","Escherichia virus T4;Mus musculus",5,"ILE A 242;ALA A 240;PHE A 237;THR A 294;ILE A 298","None;None;None;CLR A 614 ( 4.0A);CLR A 614 ( 4.1A)","1.06A","1tdrA-4dklA:undetectable","1k74A-3am6A:21.85"],["1XDK_A_9CRA500_1","RETINOIC ACID RECEPTOR RXR-ALPHA","3am6","RHODOPSIN-2","Acetabularia acetabulum",5,"ILE A  44;ALA A  47;VAL A  95;CYH A 218;LEU A 219","None;None;None;None;CLR A 401 ( 4.6A)","1.01A","1xdkA-3am6A:undetectable","1tdrA-4dklA:16.16"],["1XDK_E_9CRE1500_1","RETINOIC ACID RECEPTOR RXR-ALPHA","3am6","RHODOPSIN-2","Acetabularia acetabulum",5,"ILE A  44;ALA A  47;VAL A  95;CYH A 218;LEU A 219","None;None;None;None;CLR A 401 ( 4.6A)","1.01A","1xdkE-3am6A:undetectable","1xdkA-3am6A:21.85"],["1XIU_A_9CRA201_1","RXR-LIKE PROTEIN","3am6","RHODOPSIN-2","Acetabularia acetabulum",5,"ILE A  44;ALA A  47;VAL A  95;CYH A 218;LEU A 219","None;None;None;None;CLR A 401 ( 4.6A)","0.88A","1xiuA-3am6A:undetectable","1xdkE-3am6A:21.85"],["1XIU_B_9CRB202_1","RXR-LIKE PROTEIN","3am6","RHODOPSIN-2","Acetabularia acetabulum",5,"ILE A  44;ALA A  47;VAL A  95;CYH A 218;LEU A 219","None;None;None;None;CLR A 401 ( 4.6A)","0.90A","1xiuB-3am6A:undetectable","1xiuA-3am6A:21.43"],["1XLS_A_9CRA801_1","RETINOIC ACID RECEPTOR RXR-ALPHA","3am6","RHODOPSIN-2","Acetabularia acetabulum",5,"ILE A  44;ALA A  47;VAL A  95;CYH A 218;LEU A 219","None;None;None;None;CLR A 401 ( 4.6A)","0.94A","1xlsA-3am6A:undetectable","1xiuB-3am6A:21.43"],["1XLS_B_9CRB802_1","RETINOIC ACID RECEPTOR RXR-ALPHA","3am6","RHODOPSIN-2","Acetabularia acetabulum",5,"ILE A  44;ALA A  47;VAL A  95;CYH A 218;LEU A 219","None;None;None;None;CLR A 401 ( 4.6A)","0.93A","1xlsB-3am6A:undetectable","1xlsA-3am6A:21.97"],["1XLS_C_9CRC803_1","RETINOIC ACID RECEPTOR RXR-ALPHA","3am6","RHODOPSIN-2","Acetabularia acetabulum",5,"ILE A  44;ALA A  47;VAL A  95;CYH A 218;LEU A 219","None;None;None;None;CLR A 401 ( 4.6A)","0.93A","1xlsC-3am6A:undetectable","1xlsB-3am6A:21.97"],["1XLS_D_9CRD804_1","RETINOIC ACID RECEPTOR RXR-ALPHA","3am6","RHODOPSIN-2","Acetabularia acetabulum",5,"ILE A  44;ALA A  47;VAL A  95;CYH A 218;LEU A 219","None;None;None;None;CLR A 401 ( 4.6A)","0.94A","1xlsD-3am6A:undetectable","1xlsC-3am6A:21.97"],["1YA4_C_CTXC1383_1","CES1 PROTEIN","6aqf","ADENOSINE RECEPTOR A2A,SOLUBLE CYTOCHROME B562,ADENOSINE RECEPTOR A2A","Escherichia coli;Homo sapiens",4,"TRP A 246;PRO A 248;LEU A 244;GLY A 240","None;CLR A1202 (-4.1A);None;None","1.47A","1ya4C-6aqfA:0.5","1xlsD-3am6A:21.97"],["2AOU_B_CQAB401_0","HISTAMINE N-METHYLTRANSFERASE","4or2","SOLUBLE CYTOCHROME B562, METABOTROPIC GLUTAMATE RECEPTOR 1","Escherichia coli;Homo sapiens",4,"PRO A1056;ASP A1060;TYR A1105;THR A 653","None;None;None;CLR A1905 (-3.4A)","1.01A","2aouB-4or2A:undetectable","1ya4C-6aqfA:11.18"],["2ZZM_A_SAMA401_0","UNCHARACTERIZED PROTEIN MJ0883","5lwe","C-C CHEMOKINE RECEPTOR TYPE 9","Homo sapiens",5,"LEU A  87;GLY A  65;VAL A  58;LEU A 312;PHE A 308","79K A 401 (-4.3A);OLA A 412 ( 4.1A);None;CLR A 417 ( 4.7A);OLA A 402 (-4.1A)","1.01A","2zzmA-5lweA:undetectable","2aouB-4or2A:19.05"],["3BJW_F_SVRF509_2","PHOSPHOLIPASE A2;PHOSPHOLIPASE A2","3jd8","NIEMANN-PICK C1 PROTEIN","Homo sapiens",4,"ASN A 198;LYS A 196;PRO A 207;PHE A 209","CLR A1325 ( 3.9A);None;None;None","1.42A","3bjwD-3jd8A:undetectable","2zzmA-5lweA:22.22"],["3CR5_X_PNTX95_0","PROTEIN S100-B","6aqf","ADENOSINE RECEPTOR A2A,SOLUBLE CYTOCHROME B562,ADENOSINE RECEPTOR A2A","Escherichia coli;Homo sapiens",3,"CYH A 254;PHE A 257;PHE A 258","CLR A1203 (-4.0A);None;None","0.69A","3cr5X-6aqfA:undetectable","3bjwD-3jd8A:7.25"],["3DZU_A_9CRA7223_1","RETINOIC ACID RECEPTOR RXR-ALPHA","3am6","RHODOPSIN-2","Acetabularia acetabulum",5,"ILE A  44;ALA A  47;VAL A  95;CYH A 218;LEU A 219","None;None;None;None;CLR A 401 ( 4.6A)","1.02A","3dzuA-3am6A:undetectable","3cr5X-6aqfA:undetectable"],["3DZY_A_9CRA463_1","RETINOIC ACID RECEPTOR RXR-ALPHA","3am6","RHODOPSIN-2","Acetabularia acetabulum",5,"ILE A  44;ALA A  47;VAL A  95;CYH A 218;LEU A 219","None;None;None;None;CLR A 401 ( 4.6A)","1.04A","3dzyA-3am6A:undetectable","3dzuA-3am6A:18.61"],["3IEO_A_AMJA300_0","CARBONIC ANHYDRASE 2","5sy1","STRA6","Danio rerio",4,"ILE A 520;GLN A 417;VAL A 521;PHE A 421","CLR A 701 (-4.9A);None;None;None","1.47A","3ieoA-5sy1A:undetectable","3dzyA-3am6A:18.61"],["3LN1_A_CELA682_1","PROSTAGLANDIN G\/H SYNTHASE 2","6aqf","ADENOSINE RECEPTOR A2A,SOLUBLE CYTOCHROME B562,ADENOSINE RECEPTOR A2A","Escherichia coli;Homo sapiens",5,"VAL A 186;LEU A 187;VAL A 239;ALA A 243;LEU A 247","None;None;None;None;CLR A1202 ( 4.3A)","1.02A","3ln1A-6aqfA:undetectable","3ieoA-5sy1A:17.15"],["3LN1_B_CELB682_1","PROSTAGLANDIN G\/H SYNTHASE 2","6aqf","ADENOSINE RECEPTOR A2A,SOLUBLE CYTOCHROME B562,ADENOSINE RECEPTOR A2A","Escherichia coli;Homo sapiens",5,"VAL A 186;LEU A 187;VAL A 239;ALA A 243;LEU A 247","None;None;None;None;CLR A1202 ( 4.3A)","1.02A","3ln1B-6aqfA:undetectable","3ln1A-6aqfA:9.97"],["3LN1_C_CELC682_1","PROSTAGLANDIN G\/H SYNTHASE 2","6aqf","ADENOSINE RECEPTOR A2A,SOLUBLE CYTOCHROME B562,ADENOSINE RECEPTOR A2A","Escherichia coli;Homo sapiens",5,"VAL A 186;LEU A 187;VAL A 239;ALA A 243;LEU A 247","None;None;None;None;CLR A1202 ( 4.3A)","1.02A","3ln1C-6aqfA:undetectable","3ln1B-6aqfA:9.97"],["3LN1_D_CELD682_1","PROSTAGLANDIN G\/H SYNTHASE 2","6aqf","ADENOSINE RECEPTOR A2A,SOLUBLE CYTOCHROME B562,ADENOSINE RECEPTOR A2A","Escherichia coli;Homo sapiens",5,"VAL A 186;LEU A 187;VAL A 239;ALA A 243;LEU A 247","None;None;None;None;CLR A1202 ( 4.3A)","1.02A","3ln1D-6aqfA:undetectable","3ln1C-6aqfA:9.97"],["3OAP_A_9CRA500_1","RETINOIC ACID RECEPTOR RXR-ALPHA","3am6","RHODOPSIN-2","Acetabularia acetabulum",5,"ILE A  44;ALA A  47;VAL A  95;CYH A 218;LEU A 219","None;None;None;None;CLR A 401 ( 4.6A)","0.90A","3oapA-3am6A:undetectable","3ln1D-6aqfA:9.97"],["3UVV_B_9CRB501_1","RETINOIC ACID RECEPTOR RXR-ALPHA","3am6","RHODOPSIN-2","Acetabularia acetabulum",5,"ILE A  44;ALA A  47;VAL A  95;CYH A 218;LEU A 219","None;None;None;None;CLR A 401 ( 4.6A)","0.89A","3uvvB-3am6A:undetectable","3oapA-3am6A:22.61"],["4A84_A_DXCA1161_0","MAJOR POLLEN ALLERGEN BET V 1-A","6d35","SMOOTHENED,SOLUBLE CYTOCHROME B562,SMOOTHENED","Escherichia coli;Xenopus laevis",5,"PRO A 137;LEU A 140;TYR A 103;VAL A 102;SER A  69","CLR A1201 ( 4.8A);None;None;None;None","1.48A","4a84A-6d35A:undetectable","3uvvB-3am6A:21.74"],["4O8F_B_BRLB501_2","PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR GAMMA","4or2","SOLUBLE CYTOCHROME B562, METABOTROPIC GLUTAMATE RECEPTOR 1","Escherichia coli;Homo sapiens",4,"ILE A 638;PHE A 639;GLY A 641;ILE A 597","None;None;None;CLR A1902 ( 4.6A)","0.75A","4o8fB-4or2A:undetectable","4a84A-6d35A:undetectable"],["4O8F_B_BRLB501_2","PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR GAMMA","6bhu","MULTIDRUG RESISTANCE-ASSOCIATED PROTEIN 1","Bos taurus",4,"ILE A 969;PHE A1042;GLY A1040;ILE A1090","CLR A1606 ( 4.7A);None;None;CLR A1606 ( 4.8A)","0.66A","4o8fB-6bhuA:2.2","4o8fB-4or2A:21.52"],["4Q15_A_HFGA803_0","PROLINE--TRNA LIGASE","5l7d","SMOOTHENED HOMOLOG,SOLUBLE CYTOCHROME B562,SMOOTHENED HOMOLOG","Escherichia coli;Homo sapiens",5,"LEU A 146;VAL A 182;PRO A 124;TRP A 119;GLY A 111","None;None;None;None;CLR A1203 (-4.0A)","1.31A","4q15A-5l7dA:undetectable","4o8fB-6bhuA:0.00"],["4URO_B_NOVB2000_1","DNA GYRASE SUBUNIT B","5l7d","SMOOTHENED HOMOLOG,SOLUBLE CYTOCHROME B562,SMOOTHENED HOMOLOG","Escherichia coli;Homo sapiens",5,"SER A  96;ASP A  95;ASP A 172;SER A  89;ARG A 173","None;CLR A1203 (-3.7A);None;None;None","1.15A","4uroB-5l7dA:undetectable","4q15A-5l7dA:21.50"],["4UY8_7_TRP71002_0","TRYPTOPHANASE","5sy1","STRA6","Danio rerio",4,"ILE A 520;ASN A 519;ILE A 514;VAL A 513","CLR A 701 (-4.9A);CLR A 701 (-3.5A);None;None","1.30A","4uy87-5sy1A:undetectable","4uroB-5l7dA:16.43"],["4X5H_A_FOLA201_0","DIHYDROFOLATE REDUCTASE","4dkl","MU-TYPE OPIOID RECEPTOR, LYSOZYME CHIMERA","Mus musculus;Escherichia virus T4",5,"ILE A 242;ALA A 240;PHE A 237;THR A 294;ILE A 298","None;None;None;CLR A 614 ( 4.0A);CLR A 614 ( 4.1A)","1.12A","4x5hA-4dklA:undetectable","4uy87-5sy1A:2.91"],["4X5J_A_FOLA201_0","DIHYDROFOLATE REDUCTASE","4dkl","MU-TYPE OPIOID RECEPTOR, LYSOZYME CHIMERA","Mus musculus;Escherichia virus T4",5,"ILE A 242;ALA A 240;PHE A 237;THR A 294;ILE A 298","None;None;None;CLR A 614 ( 4.0A);CLR A 614 ( 4.1A)","1.10A","4x5jA-4dklA:undetectable","4x5hA-4dklA:16.74"],["4ZVC_A_BEZA301_0","DIGUANYLATE CYCLASE DOSC","4xnu","INTEGRAL MEMBRANE PROTEIN-DOPAMINE TRANSPORTER","Drosophila melanogaster",4,"ILE A  41;LEU A  37;ILE A 351;LEU A 347","None;CLR A 604 (-4.4A);CLR A 604 (-4.3A);None","0.81A","4zvcA-4xnuA:2.1;4zvcB-4xnuA:2.1","4x5jA-4dklA:16.74"],["4ZVC_A_BEZA301_0","DIGUANYLATE CYCLASE DOSC","4xnu","INTEGRAL MEMBRANE PROTEIN-DOPAMINE TRANSPORTER","Drosophila melanogaster",4,"ILE A 351;LEU A 347;ILE A  41;LEU A  37","CLR A 604 (-4.3A);None;None;CLR A 604 (-4.4A)","0.80A","4zvcA-4xnuA:2.1;4zvcB-4xnuA:2.1","4zvcA-4xnuA:12.17;4zvcB-4xnuA:12.17"],["5E8Q_A_FOLA201_0","DIHYDROFOLATE REDUCTASE","4dkl","MU-TYPE OPIOID RECEPTOR, LYSOZYME CHIMERA","Mus musculus;Escherichia virus T4",5,"ILE A 242;ALA A 240;PHE A 237;THR A 294;ILE A 298","None;None;None;CLR A 614 ( 4.0A);CLR A 614 ( 4.1A)","1.08A","5e8qA-4dklA:undetectable","4zvcA-4xnuA:12.17;4zvcB-4xnuA:12.17"],["5E8Q_B_FOLB201_0","DIHYDROFOLATE REDUCTASE","4dkl","MU-TYPE OPIOID RECEPTOR, LYSOZYME CHIMERA","Mus musculus;Escherichia virus T4",5,"ILE A 242;ALA A 240;PHE A 237;THR A 294;ILE A 298","None;None;None;CLR A 614 ( 4.0A);CLR A 614 ( 4.1A)","1.13A","5e8qB-4dklA:undetectable","5e8qA-4dklA:16.16"],["5IGY_A_ERYA403_1","MACROLIDE 2'-PHOSPHOTRANSFERASE II","5aw4","NA, K-ATPASE ALPHA SUBUNIT;NA+,K+-ATPASE BETA SUBUNIT","Squalus acanthias;Squalus acanthias",4,"TYR A1023;ILE A 998;TYR A1001;TYR B  40","None;None;None;CLR B3001 ( 4.0A)","1.02A","5igyA-5aw4A:undetectable","5e8qB-4dklA:16.16"],["5IH0_A_ERYA404_1","MACROLIDE 2'-PHOSPHOTRANSFERASE II","5aw4","NA, K-ATPASE ALPHA SUBUNIT;NA+,K+-ATPASE BETA SUBUNIT","Squalus acanthias;Squalus acanthias",4,"TYR A1023;ILE A 998;TYR A1001;TYR B  40","None;None;None;CLR B3001 ( 4.0A)","1.04A","5ih0A-5aw4A:undetectable","5igyA-5aw4A:16.21"],["5KIR_B_RCXB601_1","PROSTAGLANDIN G\/H SYNTHASE 2","6aqf","ADENOSINE RECEPTOR A2A,SOLUBLE CYTOCHROME B562,ADENOSINE RECEPTOR A2A","Escherichia coli;Homo sapiens",5,"VAL A 186;ALA A  99;VAL A 239;ALA A 243;LEU A 247","None;None;None;None;CLR A1202 ( 4.3A)","1.05A","5kirB-6aqfA:undetectable","5ih0A-5aw4A:16.21"],["5UJX_B_FOLB201_0","DIHYDROFOLATE REDUCTASE","4dkl","MU-TYPE OPIOID RECEPTOR, LYSOZYME CHIMERA","Mus musculus;Escherichia virus T4",5,"ILE A 242;ALA A 240;PHE A 237;THR A 294;ILE A 298","None;None;None;CLR A 614 ( 4.0A);CLR A 614 ( 4.1A)","1.15A","5ujxB-4dklA:undetectable","5kirB-6aqfA:10.30"],["5X19_J_CHDJ101_0","CYTOCHROME C OXIDASE SUBUNIT 7A1, MITOCHONDRIAL","5wvr","KLLA0C04147P","Kluyveromyces lactis",4,"ARG A 861;MET A 862;THR A 863;LEU A 864","None;None;None;CLR A1301 (-4.2A)","1.28A","5x19J-5wvrA:undetectable","5ujxB-4dklA:16.16"],["5X1B_J_CHDJ101_0","CYTOCHROME C OXIDASE SUBUNIT 7A1, MITOCHONDRIAL","5wvr","KLLA0C04147P","Kluyveromyces lactis",4,"ARG A 861;MET A 862;THR A 863;LEU A 864","None;None;None;CLR A1301 (-4.2A)","1.25A","5x1bJ-5wvrA:undetectable","5x19J-5wvrA:8.76"],["5XIP_C_HFGC1003_0","PROLYL-TRNA SYNTHETASE, PUTATIVE","5l7d","SMOOTHENED HOMOLOG,SOLUBLE CYTOCHROME B562,SMOOTHENED HOMOLOG","Escherichia coli;Homo sapiens",5,"LEU A 146;VAL A 182;PRO A 124;TRP A 119;GLY A 111","None;None;None;None;CLR A1203 (-4.0A)","1.26A","5xipC-5l7dA:undetectable","5x1bJ-5wvrA:8.76"],["5Z12_B_9CRB501_1","RETINOIC ACID RECEPTOR RXR-ALPHA","3am6","RHODOPSIN-2","Acetabularia acetabulum",5,"ILE A  44;ALA A  47;VAL A  95;CYH A 218;LEU A 219","None;None;None;None;CLR A 401 ( 4.6A)","0.97A","5z12B-3am6A:undetectable","5xipC-5l7dA:21.85"],["5Z12_C_9CRC501_1","RETINOIC ACID RECEPTOR RXR-ALPHA","3am6","RHODOPSIN-2","Acetabularia acetabulum",5,"ILE A  44;ALA A  47;VAL A  95;CYH A 218;LEU A 219","None;None;None;None;CLR A 401 ( 4.6A)","0.91A","5z12C-3am6A:undetectable","5z12B-3am6A:15.11"],["6EF6_A_BEZA401_0","AMINOGLYCOSIDE PHOSPHOTRANSFERASE","3pds","FUSION PROTEIN BETA-2 ADRENERGIC RECEPTOR\/LYSOZYME","Homo sapiens;Escherichia virus T4",5,"LEU A  75;SER A  74;THR A 123;ILE A 127;ILE A  72","None;CLR A1202 ( 4.9A);None;None;None","0.96A","6ef6A-3pdsA:1.9","5z12C-3am6A:15.11"],["6FGD_A_ACTA821_0","GEPHYRIN","5aw4","NA+,K+-ATPASE BETA SUBUNIT","Squalus acanthias",3,"ARG B  28;PHE B  25;GLY B  27","CLR B3001 (-3.5A);None;None","0.74A","6fgdA-5aw4B:undetectable","6ef6A-3pdsA:20.81"],["6NKN_J_CHDJ102_0","CYTOCHROME C OXIDASE SUBUNIT 7A1, MITOCHONDRIAL","5wvr","KLLA0C04147P","Kluyveromyces lactis",4,"ARG A 861;MET A 862;THR A 863;LEU A 864","None;None;None;CLR A1301 (-4.2A)","1.41A","6nknJ-5wvrA:undetectable","6fgdA-5aw4B:20.00"]]