SIMILAR PATTERN OF AMINO ACIDS MAPPED TO 'CJM'
DrReposER ID / Desc. | Hit PDBID |
Hit Macromolecule |
Res. Matches |
Interface | HETATM | RMSD | Dali Z-score |
Seq. Identity (%) |
View | Dock | |
---|---|---|---|---|---|---|---|---|---|---|---|
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1IEP_B_STIB202_2 (PROTO-ONCOGENETYROSINE-PROTEINKINASE ABL) |
6b3e | CYCLIN-DEPENDENTKINASE 12 (Homosapiens) | 4 / 7 | VAL A 787MET A 816ARG A 858LEU A 866 | NoneNoneTPO A 893 ( 3.0A)CJM A1102 (-4.4A) | 0.72A | 1iepB-6b3eA:23.0 | 1iepB-6b3eA:15.95 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1OPJ_A_STIA3_1 (PROTO-ONCOGENETYROSINE-PROTEINKINASE ABL1) |
6b3e | CYCLIN-DEPENDENTKINASE 12 (Homosapiens) | 6 / 12 | VAL A 741ALA A 754GLU A 774VAL A 787LEU A 866ALA A 876 | NoneCJM A1102 (-3.1A)NoneNoneCJM A1102 (-4.4A)CJM A1102 (-3.6A) | 0.49A | 1opjA-6b3eA:22.8 | 1opjA-6b3eA:15.95 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2EUF_B_LQQB401_1 (CELL DIVISIONPROTEIN KINASE 6) |
6b3e | CYCLIN-DEPENDENTKINASE 12 (Homosapiens) | 10 / 12 | ILE A 733VAL A 741LYS A 756VAL A 787PHE A 813ASP A 819ASN A 864LEU A 866ALA A 876ASP A 877 | CJM A1102 (-3.4A)NoneNoneNoneCJM A1102 ( 4.4A)CJM A1102 (-4.1A) MG A1101 ( 4.4A)CJM A1102 (-4.4A)CJM A1102 (-3.6A) MG A1101 (-2.5A) | 0.76A | 2eufB-6b3eA:34.4 | 2eufB-6b3eA:16.06 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2FUM_A_MIXA539_1 (PROBABLESERINE/THREONINE-PROTEIN KINASE PKNB) |
6b3e | CYCLIN-DEPENDENTKINASE 12 (Homosapiens) | 7 / 12 | GLY A 734VAL A 741ALA A 754ASP A 859LYS A 861ASN A 864ASP A 877 | CJM A1102 (-3.4A)NoneCJM A1102 (-3.1A) MG A1101 (-3.7A)None MG A1101 ( 4.4A) MG A1101 (-2.5A) | 0.83A | 2fumA-6b3eA:25.7 | 2fumA-6b3eA:13.36 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2IVU_A_ZD6A3015_0 (PROTO-ONCOGENETYROSINE-PROTEINKINASE RECEPTOR RETPRECURSOR) |
6b3e | CYCLIN-DEPENDENTKINASE 12 (Homosapiens) | 8 / 12 | GLY A 734VAL A 741LYS A 756GLU A 774LEU A 778LEU A 811TYR A 815ASP A 877 | CJM A1102 (-3.4A)NoneNoneNoneNoneNoneCJM A1102 (-4.1A) MG A1101 (-2.5A) | 0.87A | 2ivuA-6b3eA:25.7 | 2ivuA-6b3eA:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2PL0_A_STIA200_1 (PROTO-ONCOGENETYROSINE-PROTEINKINASE LCK) |
6b3e | CYCLIN-DEPENDENTKINASE 12 (Homosapiens) | 7 / 12 | VAL A 741ALA A 754GLU A 774VAL A 787TYR A 815LEU A 866ALA A 876 | NoneCJM A1102 (-3.1A)NoneNoneCJM A1102 (-4.1A)CJM A1102 (-4.4A)CJM A1102 (-3.6A) | 0.67A | 2pl0A-6b3eA:22.8 | 2pl0A-6b3eA:17.87 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2WGJ_A_VGHA2346_1 (HEPATOCYTE GROWTHFACTOR RECEPTOR) |
6b3e | CYCLIN-DEPENDENTKINASE 12 (Homosapiens) | 7 / 12 | GLY A 734VAL A 741ALA A 754TYR A 815MET A 816ALA A 876ASP A 877 | CJM A1102 (-3.4A)NoneCJM A1102 (-3.1A)CJM A1102 (-4.1A)NoneCJM A1102 (-3.6A) MG A1101 (-2.5A) | 0.71A | 2wgjA-6b3eA:23.8 | 2wgjA-6b3eA:19.12 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2Y7J_A_B49A1294_1 (PHOSPHORYLASE BKINASE GAMMACATALYTIC CHAIN,TESTIS/LIVER ISOFORM) |
6b3e | CYCLIN-DEPENDENTKINASE 12 (Homosapiens) | 6 / 12 | ILE A 733VAL A 741ALA A 754PHE A 813MET A 816LEU A 866 | CJM A1102 (-3.4A)NoneCJM A1102 (-3.1A)CJM A1102 ( 4.4A)NoneCJM A1102 (-4.4A) | 0.52A | 2y7jA-6b3eA:29.0 | 2y7jA-6b3eA:11.82 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2Y7J_B_B49B1294_1 (PHOSPHORYLASE BKINASE GAMMACATALYTIC CHAIN,TESTIS/LIVER ISOFORM) |
6b3e | CYCLIN-DEPENDENTKINASE 12 (Homosapiens) | 6 / 10 | ILE A 733VAL A 741ALA A 754PHE A 813MET A 816LEU A 866 | CJM A1102 (-3.4A)NoneCJM A1102 (-3.1A)CJM A1102 ( 4.4A)NoneCJM A1102 (-4.4A) | 0.54A | 2y7jB-6b3eA:29.2 | 2y7jB-6b3eA:11.82 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2Y7J_C_B49C1294_1 (PHOSPHORYLASE BKINASE GAMMACATALYTIC CHAIN,TESTIS/LIVER ISOFORM) |
6b3e | CYCLIN-DEPENDENTKINASE 12 (Homosapiens) | 6 / 10 | ILE A 733VAL A 741ALA A 754PHE A 813MET A 816LEU A 866 | CJM A1102 (-3.4A)NoneCJM A1102 (-3.1A)CJM A1102 ( 4.4A)NoneCJM A1102 (-4.4A) | 0.56A | 2y7jC-6b3eA:22.2 | 2y7jC-6b3eA:11.82 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2Y7J_D_B49D1294_1 (PHOSPHORYLASE BKINASE GAMMACATALYTIC CHAIN,TESTIS/LIVER ISOFORM) |
6b3e | CYCLIN-DEPENDENTKINASE 12 (Homosapiens) | 6 / 10 | ILE A 733VAL A 741ALA A 754PHE A 813MET A 816LEU A 866 | CJM A1102 (-3.4A)NoneCJM A1102 (-3.1A)CJM A1102 ( 4.4A)NoneCJM A1102 (-4.4A) | 0.54A | 2y7jD-6b3eA:29.0 | 2y7jD-6b3eA:11.82 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3G5D_B_1N1B1_1 (PROTO-ONCOGENETYROSINE-PROTEINKINASE SRC) |
6b3e | CYCLIN-DEPENDENTKINASE 12 (Homosapiens) | 8 / 12 | VAL A 741ALA A 754LYS A 756GLU A 774VAL A 787TYR A 815LEU A 866ALA A 876 | NoneCJM A1102 (-3.1A)NoneNoneNoneCJM A1102 (-4.1A)CJM A1102 (-4.4A)CJM A1102 (-3.6A) | 0.85A | 3g5dB-6b3eA:24.5 | 3g5dB-6b3eA:15.81 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3GVU_A_STIA1001_1 (TYROSINE-PROTEINKINASE ABL2) |
6b3e | CYCLIN-DEPENDENTKINASE 12 (Homosapiens) | 6 / 12 | VAL A 741ALA A 754GLU A 774VAL A 787LEU A 866ALA A 876 | NoneCJM A1102 (-3.1A)NoneNoneCJM A1102 (-4.4A)CJM A1102 (-3.6A) | 0.55A | 3gvuA-6b3eA:23.4 | 3gvuA-6b3eA:13.73 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3IK3_A_0LIA1_1 (PROTO-ONCOGENETYROSINE-PROTEINKINASE ABL1) |
6b3e | CYCLIN-DEPENDENTKINASE 12 (Homosapiens) | 5 / 12 | ALA A 754GLU A 774VAL A 787LEU A 866ALA A 876 | CJM A1102 (-3.1A)NoneNoneCJM A1102 (-4.4A)CJM A1102 (-3.6A) | 0.54A | 3ik3A-6b3eA:23.4 | 3ik3A-6b3eA:16.30 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3IK3_A_0LIA1_1 (PROTO-ONCOGENETYROSINE-PROTEINKINASE ABL1) |
6b3e | CYCLIN-DEPENDENTKINASE 12 (Homosapiens) | 5 / 12 | ALA A 754VAL A 787HIS A 857LEU A 866ALA A 876 | CJM A1102 (-3.1A)NoneNoneCJM A1102 (-4.4A)CJM A1102 (-3.6A) | 0.39A | 3ik3A-6b3eA:23.4 | 3ik3A-6b3eA:16.30 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3IK3_B_0LIB2_1 (PROTO-ONCOGENETYROSINE-PROTEINKINASE ABL1) |
6b3e | CYCLIN-DEPENDENTKINASE 12 (Homosapiens) | 6 / 12 | ALA A 754GLU A 774VAL A 787HIS A 857LEU A 866ALA A 876 | CJM A1102 (-3.1A)NoneNoneNoneCJM A1102 (-4.4A)CJM A1102 (-3.6A) | 0.56A | 3ik3B-6b3eA:23.3 | 3ik3B-6b3eA:16.30 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3LFA_A_1N1A361_1 (MITOGEN-ACTIVATEDPROTEIN KINASE 14) |
6b3e | CYCLIN-DEPENDENTKINASE 12 (Homosapiens) | 5 / 8 | ALA A 754LYS A 756GLU A 774LEU A 811MET A 816 | CJM A1102 (-3.1A)NoneNoneNoneNone | 0.51A | 3lfaA-6b3eA:26.9 | 3lfaA-6b3eA:12.17 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3LXK_A_MI1A1125_1 (TYROSINE-PROTEINKINASE JAK3) |
6b3e | CYCLIN-DEPENDENTKINASE 12 (Homosapiens) | 8 / 12 | GLY A 734VAL A 741ALA A 754LYS A 756VAL A 787TYR A 815ALA A 876ASP A 877 | CJM A1102 (-3.4A)NoneCJM A1102 (-3.1A)NoneNoneCJM A1102 (-4.1A)CJM A1102 (-3.6A) MG A1101 (-2.5A) | 1.03A | 3lxkA-6b3eA:25.1 | 3lxkA-6b3eA:16.16 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3LXK_A_MI1A1125_1 (TYROSINE-PROTEINKINASE JAK3) |
6b3e | CYCLIN-DEPENDENTKINASE 12 (Homosapiens) | 8 / 12 | GLY A 734VAL A 741ALA A 754VAL A 787TYR A 815LEU A 866ALA A 876ASP A 877 | CJM A1102 (-3.4A)NoneCJM A1102 (-3.1A)NoneCJM A1102 (-4.1A)CJM A1102 (-4.4A)CJM A1102 (-3.6A) MG A1101 (-2.5A) | 1.02A | 3lxkA-6b3eA:25.1 | 3lxkA-6b3eA:16.16 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3MIY_A_B49A1_1 (TYROSINE-PROTEINKINASE ITK/TSK) |
6b3e | CYCLIN-DEPENDENTKINASE 12 (Homosapiens) | 7 / 11 | ILE A 733ALA A 754LYS A 756VAL A 787PHE A 813MET A 816LEU A 866 | CJM A1102 (-3.4A)CJM A1102 (-3.1A)NoneNoneCJM A1102 ( 4.4A)NoneCJM A1102 (-4.4A) | 0.82A | 3miyA-6b3eA:23.9 | 3miyA-6b3eA:16.02 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3MIY_B_B49B2_1 (TYROSINE-PROTEINKINASE ITK/TSK) |
6b3e | CYCLIN-DEPENDENTKINASE 12 (Homosapiens) | 6 / 9 | ILE A 733ALA A 754LYS A 756PHE A 813MET A 816LEU A 866 | CJM A1102 (-3.4A)CJM A1102 (-3.1A)NoneCJM A1102 ( 4.4A)NoneCJM A1102 (-4.4A) | 0.64A | 3miyB-6b3eA:23.7 | 3miyB-6b3eA:16.02 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3OEZ_A_STIA601_1 (PROTO-ONCOGENETYROSINE-PROTEINKINASE SRC) |
6b3e | CYCLIN-DEPENDENTKINASE 12 (Homosapiens) | 7 / 12 | VAL A 741ALA A 754GLU A 774VAL A 787TYR A 815LEU A 866ALA A 876 | NoneCJM A1102 (-3.1A)NoneNoneCJM A1102 (-4.1A)CJM A1102 (-4.4A)CJM A1102 (-3.6A) | 0.66A | 3oezA-6b3eA:23.0 | 3oezA-6b3eA:15.81 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3OEZ_B_STIB601_1 (PROTO-ONCOGENETYROSINE-PROTEINKINASE SRC) |
6b3e | CYCLIN-DEPENDENTKINASE 12 (Homosapiens) | 7 / 12 | VAL A 741ALA A 754LYS A 756GLU A 774TYR A 815LEU A 866ALA A 876 | NoneCJM A1102 (-3.1A)NoneNoneCJM A1102 (-4.1A)CJM A1102 (-4.4A)CJM A1102 (-3.6A) | 0.75A | 3oezB-6b3eA:23.2 | 3oezB-6b3eA:15.81 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3PYY_B_STIB4_1 (V-ABL ABELSON MURINELEUKEMIA VIRALONCOGENE HOMOLOG 1ISOFORM B VARIANT) |
6b3e | CYCLIN-DEPENDENTKINASE 12 (Homosapiens) | 6 / 12 | VAL A 741ALA A 754GLU A 774VAL A 787LEU A 866ALA A 876 | NoneCJM A1102 (-3.1A)NoneNoneCJM A1102 (-4.4A)CJM A1102 (-3.6A) | 0.55A | 3pyyB-6b3eA:22.9 | 3pyyB-6b3eA:12.42 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3RGF_A_BAXA465_1 (CYCLIN-DEPENDENTKINASE 8) |
6b3e | CYCLIN-DEPENDENTKINASE 12 (Homosapiens) | 8 / 12 | VAL A 741ALA A 754GLU A 774LEU A 778PHE A 813TYR A 815HIS A 857ALA A 876 | NoneCJM A1102 (-3.1A)NoneNoneCJM A1102 ( 4.4A)CJM A1102 (-4.1A)NoneCJM A1102 (-3.6A) | 0.60A | 3rgfA-6b3eA:10.9 | 3rgfA-6b3eA:13.71 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3TI1_A_B49A299_1 (CYCLIN-DEPENDENTKINASE 2) |
6b3e | CYCLIN-DEPENDENTKINASE 12 (Homosapiens) | 5 / 9 | ILE A 733ALA A 754PHE A 813ASP A 819LEU A 866 | CJM A1102 (-3.4A)CJM A1102 (-3.1A)CJM A1102 ( 4.4A)CJM A1102 (-4.1A)CJM A1102 (-4.4A) | 0.41A | 3ti1A-6b3eA:32.2 | 3ti1A-6b3eA:21.31 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3TI1_A_B49A299_1 (CYCLIN-DEPENDENTKINASE 2) |
6b3e | CYCLIN-DEPENDENTKINASE 12 (Homosapiens) | 5 / 9 | ILE A 733ALA A 754VAL A 787ASP A 819LEU A 866 | CJM A1102 (-3.4A)CJM A1102 (-3.1A)NoneCJM A1102 (-4.1A)CJM A1102 (-4.4A) | 0.78A | 3ti1A-6b3eA:32.2 | 3ti1A-6b3eA:21.31 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3TI1_A_B49A299_1 (CYCLIN-DEPENDENTKINASE 2) |
6b3e | CYCLIN-DEPENDENTKINASE 12 (Homosapiens) | 5 / 9 | ILE A 733VAL A 787ASP A 819LEU A 866ASP A 877 | CJM A1102 (-3.4A)NoneCJM A1102 (-4.1A)CJM A1102 (-4.4A) MG A1101 (-2.5A) | 0.73A | 3ti1A-6b3eA:32.2 | 3ti1A-6b3eA:21.31 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3WZD_A_LEVA1201_2 (VASCULAR ENDOTHELIALGROWTH FACTORRECEPTOR 2) |
6b3e | CYCLIN-DEPENDENTKINASE 12 (Homosapiens) | 4 / 5 | ILE A 777VAL A 787LEU A 866ASP A 877 | NoneNoneCJM A1102 (-4.4A) MG A1101 (-2.5A) | 0.91A | 3wzdA-6b3eA:22.5 | 3wzdA-6b3eA:15.44 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ZOS_A_0LIA1000_1 (EPITHELIAL DISCOIDINDOMAIN-CONTAININGRECEPTOR 1) |
6b3e | CYCLIN-DEPENDENTKINASE 12 (Homosapiens) | 7 / 12 | ALA A 754LYS A 756GLU A 774HIS A 857ARG A 858LEU A 866ALA A 876 | CJM A1102 (-3.1A)NoneNoneNoneTPO A 893 ( 3.0A)CJM A1102 (-4.4A)CJM A1102 (-3.6A) | 0.76A | 3zosA-6b3eA:22.2 | 3zosA-6b3eA:15.04 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ZOS_B_0LIB1000_1 (EPITHELIAL DISCOIDINDOMAIN-CONTAININGRECEPTOR 1) |
6b3e | CYCLIN-DEPENDENTKINASE 12 (Homosapiens) | 7 / 12 | ALA A 754LYS A 756GLU A 774HIS A 857ARG A 858LEU A 866ALA A 876 | CJM A1102 (-3.1A)NoneNoneNoneTPO A 893 ( 3.0A)CJM A1102 (-4.4A)CJM A1102 (-3.6A) | 0.74A | 3zosB-6b3eA:22.3 | 3zosB-6b3eA:15.04 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ANQ_A_VGHA9000_1 (ALK TYROSINE KINASERECEPTOR) |
6b3e | CYCLIN-DEPENDENTKINASE 12 (Homosapiens) | 6 / 9 | VAL A 741ALA A 754MET A 816LEU A 866ALA A 876ASP A 877 | NoneCJM A1102 (-3.1A)NoneCJM A1102 (-4.4A)CJM A1102 (-3.6A) MG A1101 (-2.5A) | 0.77A | 4anqA-6b3eA:22.7 | 4anqA-6b3eA:11.73 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4BKJ_A_STIA1000_1 (EPITHELIAL DISCOIDINDOMAIN-CONTAININGRECEPTOR 1) |
6b3e | CYCLIN-DEPENDENTKINASE 12 (Homosapiens) | 7 / 12 | VAL A 741ALA A 754GLU A 774ILE A 777TYR A 815LEU A 866ALA A 876 | NoneCJM A1102 (-3.1A)NoneNoneCJM A1102 (-4.1A)CJM A1102 (-4.4A)CJM A1102 (-3.6A) | 0.64A | 4bkjA-6b3eA:22.5 | 4bkjA-6b3eA:15.04 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4BKJ_B_STIB1000_1 (EPITHELIAL DISCOIDINDOMAIN-CONTAININGRECEPTOR 1) |
6b3e | CYCLIN-DEPENDENTKINASE 12 (Homosapiens) | 6 / 12 | VAL A 741ALA A 754GLU A 774ILE A 777LEU A 866ALA A 876 | NoneCJM A1102 (-3.1A)NoneNoneCJM A1102 (-4.4A)CJM A1102 (-3.6A) | 0.62A | 4bkjB-6b3eA:22.6 | 4bkjB-6b3eA:15.04 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4BKJ_B_STIB1000_2 (EPITHELIAL DISCOIDINDOMAIN-CONTAININGRECEPTOR 1) |
6b3e | CYCLIN-DEPENDENTKINASE 12 (Homosapiens) | 4 / 5 | LEU A 781TYR A 815MET A 816ARG A 773 | NoneCJM A1102 (-4.1A)NoneNone | 1.31A | 4bkjB-6b3eA:22.6 | 4bkjB-6b3eA:15.04 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4BKJ_B_STIB1000_2 (EPITHELIAL DISCOIDINDOMAIN-CONTAININGRECEPTOR 1) |
6b3e | CYCLIN-DEPENDENTKINASE 12 (Homosapiens) | 4 / 5 | LEU A 781TYR A 815MET A 816ARG A 858 | NoneCJM A1102 (-4.1A)NoneTPO A 893 ( 3.0A) | 0.88A | 4bkjB-6b3eA:22.6 | 4bkjB-6b3eA:15.04 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4C8B_A_0LIA1000_1 (RECEPTOR-INTERACTINGSERINE/THREONINE-PROTEIN KINASE 2) |
6b3e | CYCLIN-DEPENDENTKINASE 12 (Homosapiens) | 7 / 12 | ALA A 754LYS A 756GLU A 774LEU A 778HIS A 857LEU A 866ALA A 876 | CJM A1102 (-3.1A)NoneNoneNoneNoneCJM A1102 (-4.4A)CJM A1102 (-3.6A) | 0.74A | 4c8bA-6b3eA:24.2 | 4c8bA-6b3eA:12.23 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4C8B_B_0LIB1000_1 (RECEPTOR-INTERACTINGSERINE/THREONINE-PROTEIN KINASE 2) |
6b3e | CYCLIN-DEPENDENTKINASE 12 (Homosapiens) | 7 / 12 | ALA A 754LYS A 756GLU A 774LEU A 778HIS A 857LEU A 866ALA A 876 | CJM A1102 (-3.1A)NoneNoneNoneNoneCJM A1102 (-4.4A)CJM A1102 (-3.6A) | 0.81A | 4c8bB-6b3eA:24.0 | 4c8bB-6b3eA:12.23 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4CSV_A_STIA1265_1 (SRC-ABL TYROSINEKINASE ANCESTOR) |
6b3e | CYCLIN-DEPENDENTKINASE 12 (Homosapiens) | 8 / 12 | VAL A 741ALA A 754GLU A 774ILE A 777VAL A 787TYR A 815LEU A 866ALA A 876 | NoneCJM A1102 (-3.1A)NoneNoneNoneCJM A1102 (-4.1A)CJM A1102 (-4.4A)CJM A1102 (-3.6A) | 0.68A | 4csvA-6b3eA:23.8 | 4csvA-6b3eA:14.06 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4OGR_A_ADNA401_1 (CYCLIN-DEPENDENTKINASE 9) |
6b3e | CYCLIN-DEPENDENTKINASE 12 (Homosapiens) | 7 / 8 | ILE A 733VAL A 741ALA A 754ASP A 819ASN A 864LEU A 866ASP A 877 | CJM A1102 (-3.4A)NoneCJM A1102 (-3.1A)CJM A1102 (-4.1A) MG A1101 ( 4.4A)CJM A1102 (-4.4A) MG A1101 (-2.5A) | 0.41A | 4ogrA-6b3eA:40.3 | 4ogrA-6b3eA:15.88 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4OGR_I_ADNI401_1 (CYCLIN-DEPENDENTKINASE 9) |
6b3e | CYCLIN-DEPENDENTKINASE 12 (Homosapiens) | 7 / 9 | ILE A 733VAL A 741ALA A 754ASP A 819ASN A 864LEU A 866ASP A 877 | CJM A1102 (-3.4A)NoneCJM A1102 (-3.1A)CJM A1102 (-4.1A) MG A1101 ( 4.4A)CJM A1102 (-4.4A) MG A1101 (-2.5A) | 0.48A | 4ogrI-6b3eA:40.0 | 4ogrI-6b3eA:15.88 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4QMN_A_DB8A401_1 (SERINE/THREONINE-PROTEIN KINASE 24) |
6b3e | CYCLIN-DEPENDENTKINASE 12 (Homosapiens) | 7 / 12 | ILE A 733ALA A 754GLU A 774TYR A 815LEU A 866ALA A 876ASP A 877 | CJM A1102 (-3.4A)CJM A1102 (-3.1A)NoneCJM A1102 (-4.1A)CJM A1102 (-4.4A)CJM A1102 (-3.6A) MG A1101 (-2.5A) | 0.78A | 4qmnA-6b3eA:29.6 | 4qmnA-6b3eA:13.59 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4QMN_A_DB8A401_1 (SERINE/THREONINE-PROTEIN KINASE 24) |
6b3e | CYCLIN-DEPENDENTKINASE 12 (Homosapiens) | 6 / 12 | ILE A 733ALA A 754LYS A 756GLU A 774TYR A 815LEU A 866 | CJM A1102 (-3.4A)CJM A1102 (-3.1A)NoneNoneCJM A1102 (-4.1A)CJM A1102 (-4.4A) | 0.81A | 4qmnA-6b3eA:29.6 | 4qmnA-6b3eA:13.59 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4QMS_A_1N1A401_1 (SERINE/THREONINE-PROTEIN KINASE 24) |
6b3e | CYCLIN-DEPENDENTKINASE 12 (Homosapiens) | 7 / 11 | ILE A 733ALA A 754LYS A 756GLU A 774TYR A 815LEU A 866ASP A 877 | CJM A1102 (-3.4A)CJM A1102 (-3.1A)NoneNoneCJM A1102 (-4.1A)CJM A1102 (-4.4A) MG A1101 (-2.5A) | 0.90A | 4qmsA-6b3eA:29.7 | 4qmsA-6b3eA:13.59 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4QMZ_A_B49A401_1 (SERINE/THREONINE-PROTEIN KINASE 24) |
6b3e | CYCLIN-DEPENDENTKINASE 12 (Homosapiens) | 6 / 12 | ILE A 733GLY A 734VAL A 741ALA A 754TYR A 815LEU A 866 | CJM A1102 (-3.4A)CJM A1102 (-3.4A)NoneCJM A1102 (-3.1A)CJM A1102 (-4.1A)CJM A1102 (-4.4A) | 0.67A | 4qmzA-6b3eA:30.0 | 4qmzA-6b3eA:13.59 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4TWP_A_AXIA601_1 (TYROSINE-PROTEINKINASE ABL1) |
6b3e | CYCLIN-DEPENDENTKINASE 12 (Homosapiens) | 8 / 12 | VAL A 741ALA A 754LYS A 756MET A 816ASN A 864LEU A 866ALA A 876ASP A 877 | NoneCJM A1102 (-3.1A)NoneNone MG A1101 ( 4.4A)CJM A1102 (-4.4A)CJM A1102 (-3.6A) MG A1101 (-2.5A) | 0.52A | 4twpA-6b3eA:25.5 | 4twpA-6b3eA:15.25 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4TYJ_A_0LIA801_1 (FIBROBLAST GROWTHFACTOR RECEPTOR 4) |
6b3e | CYCLIN-DEPENDENTKINASE 12 (Homosapiens) | 5 / 12 | ALA A 754GLU A 774HIS A 857LEU A 866ALA A 876 | CJM A1102 (-3.1A)NoneNoneCJM A1102 (-4.4A)CJM A1102 (-3.6A) | 0.61A | 4tyjA-6b3eA:22.6 | 4tyjA-6b3eA:12.83 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4V04_A_0LIA1772_1 (FIBROBLAST GROWTHFACTOR RECEPTOR 1(FMS-RELATEDTYROSINE KINASE 2,PFEIFFER SYNDROME),ISOFORM CRA_B) |
6b3e | CYCLIN-DEPENDENTKINASE 12 (Homosapiens) | 6 / 12 | VAL A 741ALA A 754GLU A 774CYH A 850HIS A 857ALA A 876 | NoneCJM A1102 (-3.1A)NoneNoneNoneCJM A1102 (-3.6A) | 1.17A | 4v04A-6b3eA:22.1 | 4v04A-6b3eA:16.86 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4XV2_A_P06A801_1 (SERINE/THREONINE-PROTEIN KINASE B-RAF) |
6b3e | CYCLIN-DEPENDENTKINASE 12 (Homosapiens) | 5 / 12 | VAL A 741ALA A 754LYS A 756ASP A 877PHE A 878 | NoneCJM A1102 (-3.1A)None MG A1101 (-2.5A)None | 0.59A | 4xv2A-6b3eA:23.7 | 4xv2A-6b3eA:16.47 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4XV2_B_P06B801_1 (SERINE/THREONINE-PROTEIN KINASE B-RAF) |
6b3e | CYCLIN-DEPENDENTKINASE 12 (Homosapiens) | 5 / 12 | ALA A 754LYS A 756LEU A 778ASP A 877PHE A 878 | CJM A1102 (-3.1A)NoneNone MG A1101 (-2.5A)None | 0.69A | 4xv2B-6b3eA:24.1 | 4xv2B-6b3eA:16.47 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5CSW_A_P06A801_1 (SERINE/THREONINE-PROTEIN KINASE B-RAF) |
6b3e | CYCLIN-DEPENDENTKINASE 12 (Homosapiens) | 5 / 12 | VAL A 741ALA A 754LYS A 756LEU A 778PHE A 878 | NoneCJM A1102 (-3.1A)NoneNoneNone | 0.66A | 5cswA-6b3eA:23.6 | 5cswA-6b3eA:17.43 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5CSW_B_P06B801_1 (SERINE/THREONINE-PROTEIN KINASE B-RAF) |
6b3e | CYCLIN-DEPENDENTKINASE 12 (Homosapiens) | 5 / 12 | VAL A 741ALA A 754LYS A 756LEU A 778PHE A 878 | NoneCJM A1102 (-3.1A)NoneNoneNone | 0.62A | 5cswB-6b3eA:23.4 | 5cswB-6b3eA:17.43 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5I9Y_A_1N1A1001_1 (EPHRIN TYPE-ARECEPTOR 2) |
6b3e | CYCLIN-DEPENDENTKINASE 12 (Homosapiens) | 6 / 12 | ILE A 733ALA A 754LYS A 756GLU A 774TYR A 815LEU A 866 | CJM A1102 (-3.4A)CJM A1102 (-3.1A)NoneNoneCJM A1102 (-4.1A)CJM A1102 (-4.4A) | 0.70A | 5i9yA-6b3eA:23.4 | 5i9yA-6b3eA:16.79 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5L2I_A_LQQA900_1 (CYCLIN-DEPENDENTKINASE 6) |
6b3e | CYCLIN-DEPENDENTKINASE 12 (Homosapiens) | 9 / 12 | GLY A 734VAL A 741ALA A 754VAL A 787PHE A 813ASP A 819LEU A 866ALA A 876ASP A 877 | CJM A1102 (-3.4A)NoneCJM A1102 (-3.1A)NoneCJM A1102 ( 4.4A)CJM A1102 (-4.1A)CJM A1102 (-4.4A)CJM A1102 (-3.6A) MG A1101 (-2.5A) | 0.89A | 5l2iA-6b3eA:13.1 | 5l2iA-6b3eA:16.06 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5L2I_A_LQQA900_1 (CYCLIN-DEPENDENTKINASE 6) |
6b3e | CYCLIN-DEPENDENTKINASE 12 (Homosapiens) | 7 / 12 | ILE A 733GLY A 734VAL A 741ALA A 754PHE A 813ASP A 819LEU A 866 | CJM A1102 (-3.4A)CJM A1102 (-3.4A)NoneCJM A1102 (-3.1A)CJM A1102 ( 4.4A)CJM A1102 (-4.1A)CJM A1102 (-4.4A) | 0.74A | 5l2iA-6b3eA:13.1 | 5l2iA-6b3eA:16.06 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5L2T_A_6ZZA900_1 (CYCLIN-DEPENDENTKINASE 6) |
6b3e | CYCLIN-DEPENDENTKINASE 12 (Homosapiens) | 7 / 12 | GLY A 734VAL A 787PHE A 813ASP A 819LEU A 866ALA A 876ASP A 877 | CJM A1102 (-3.4A)NoneCJM A1102 ( 4.4A)CJM A1102 (-4.1A)CJM A1102 (-4.4A)CJM A1102 (-3.6A) MG A1101 (-2.5A) | 0.96A | 5l2tA-6b3eA:13.4 | 5l2tA-6b3eA:16.06 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5L2T_A_6ZZA900_1 (CYCLIN-DEPENDENTKINASE 6) |
6b3e | CYCLIN-DEPENDENTKINASE 12 (Homosapiens) | 8 / 12 | ILE A 733GLY A 734ALA A 754VAL A 787PHE A 813ASP A 819LEU A 866ALA A 876 | CJM A1102 (-3.4A)CJM A1102 (-3.4A)CJM A1102 (-3.1A)NoneCJM A1102 ( 4.4A)CJM A1102 (-4.1A)CJM A1102 (-4.4A)CJM A1102 (-3.6A) | 1.03A | 5l2tA-6b3eA:13.4 | 5l2tA-6b3eA:16.06 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5L2T_A_6ZZA900_1 (CYCLIN-DEPENDENTKINASE 6) |
6b3e | CYCLIN-DEPENDENTKINASE 12 (Homosapiens) | 8 / 12 | ILE A 733VAL A 741ALA A 754VAL A 787PHE A 813ASP A 819LEU A 866ALA A 876 | CJM A1102 (-3.4A)NoneCJM A1102 (-3.1A)NoneCJM A1102 ( 4.4A)CJM A1102 (-4.1A)CJM A1102 (-4.4A)CJM A1102 (-3.6A) | 0.91A | 5l2tA-6b3eA:13.4 | 5l2tA-6b3eA:16.06 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5LW1_B_ADNB401_1 (MITOGEN-ACTIVATEDPROTEIN KINASE 8) |
6b3e | CYCLIN-DEPENDENTKINASE 12 (Homosapiens) | 5 / 9 | ILE A 733GLY A 734VAL A 741ALA A 754MET A 816 | CJM A1102 (-3.4A)CJM A1102 (-3.4A)NoneCJM A1102 (-3.1A)None | 0.67A | 5lw1B-6b3eA:28.2 | 5lw1B-6b3eA:23.33 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5MO4_A_NILA601_2 (TYROSINE-PROTEINKINASE ABL1) |
6b3e | CYCLIN-DEPENDENTKINASE 12 (Homosapiens) | 5 / 12 | ALA A 754VAL A 787HIS A 857LEU A 866ALA A 876 | CJM A1102 (-3.1A)NoneNoneCJM A1102 (-4.4A)CJM A1102 (-3.6A) | 0.50A | 5mo4A-6b3eA:20.1 | 5mo4A-6b3eA:10.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5OWR_A_1N1A401_1 (SERINE/THREONINE-PROTEIN KINASE 10) |
6b3e | CYCLIN-DEPENDENTKINASE 12 (Homosapiens) | 4 / 8 | ALA A 754GLU A 774LEU A 866ASP A 877 | CJM A1102 (-3.1A)NoneCJM A1102 (-4.4A) MG A1101 (-2.5A) | 0.41A | 5owrA-6b3eA:16.8 | 5owrA-6b3eA:15.91 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5YF9_B_NIOB401_1 (CASEIN KINASE IISUBUNIT ALPHA') |
6b3e | CYCLIN-DEPENDENTKINASE 12 (Homosapiens) | 4 / 7 | VAL A 741LYS A 756PHE A 813ASP A 877 | NoneNoneCJM A1102 ( 4.4A) MG A1101 (-2.5A) | 0.64A | 5yf9B-6b3eA:16.3 | 5yf9B-6b3eA:22.35 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5YWM_X_NIOX403_0 (CASEIN KINASE IISUBUNIT ALPHA') |
6b3e | CYCLIN-DEPENDENTKINASE 12 (Homosapiens) | 4 / 7 | VAL A 741LYS A 756PHE A 813ASP A 877 | NoneNoneCJM A1102 ( 4.4A) MG A1101 (-2.5A) | 0.46A | 5ywmX-6b3eA:32.1 | 5ywmX-6b3eA:22.35 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6BSD_A_1N1A901_0 (EPITHELIAL DISCOIDINDOMAIN-CONTAININGRECEPTOR 1) |
6b3e | CYCLIN-DEPENDENTKINASE 12 (Homosapiens) | 7 / 12 | VAL A 741ALA A 754LYS A 756GLU A 774TYR A 815MET A 816LEU A 866 | NoneCJM A1102 (-3.1A)NoneNoneCJM A1102 (-4.1A)NoneCJM A1102 (-4.4A) | 0.50A | 6bsdA-6b3eA:22.3 | 6bsdA-6b3eA:15.00 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 6HD4_A_STIA604_0 (TYROSINE-PROTEINKINASE ABL1) |
6b3e | CYCLIN-DEPENDENTKINASE 12 (Homosapiens) | 6 / 12 | VAL A 741ALA A 754GLU A 774VAL A 787LEU A 866ALA A 876 | NoneCJM A1102 (-3.1A)NoneNoneCJM A1102 (-4.4A)CJM A1102 (-3.6A) | 0.56A | 6hd4A-6b3eA:22.6 | 6hd4A-6b3eA:32.50 |