SIMILAR PATTERN OF AMINO ACIDS MAPPED TO 'CIL'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4AQL_A_TXCA1452_1 (GUANINE DEAMINASE)	1itu	RENAL DIPEPTIDASE (Homo sapiens)	5 / 12	ARG A 230 HIS A 152 ALA A 159 SER A 66 ASP A 22	CIL A 451 (-4.0A) CIL A 451 (-4.0A) None ZN A 401 ( 3.7A) ZN A 401 ( 2.2A)	1.36A	4aqlA-1ituA: 5.9	4aqlA-1ituA: 21.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4C49_D_HCYD1384_1 (CORTICOSTEROID-BINDI NG GLOBULIN)	1itu	RENAL DIPEPTIDASE (Homo sapiens)	5 / 12	THR A 149 ARG A 229 ASN A 231 HIS A 152 TRP A 162	None None None CIL A 451 (-4.0A) None	1.31A	4c49D-1ituA: 0.0	4c49D-1ituA: 22.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5DV4_A_NMYA601_2 (CCR4-NOT TRANSCRIPTION COMPLEX SUBUNIT 6-LIKE)	1itu	RENAL DIPEPTIDASE (Homo sapiens)	3 / 3	GLU A 125 TRP A 162 ASN A 250	ZN A 401 ( 2.5A) None CIL A 451 ( 4.7A)	0.58A	5dv4A-1ituA: 0.6	5dv4A-1ituA: 22.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6BTX_A_EDTA503_0 (SOLUTE CARRIER FAMILY 39 (IRON-REGULATED TRANSPORTER))	1itu	RENAL DIPEPTIDASE (Homo sapiens)	4 / 7	TRP A 25 SER A 66 HIS A 152 GLY A 126	CIL A 451 ( 4.4A) ZN A 401 ( 3.7A) CIL A 451 (-4.0A) None	1.03A	6btxA-1ituA: undetectable	6btxA-1ituA: 21.37

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["4AQL_A_TXCA1452_1","GUANINE DEAMINASE","1itu","RENAL DIPEPTIDASE","Homo sapiens",5,"ARG A 230;HIS A 152;ALA A 159;SER A  66;ASP A  22","CIL A 451 (-4.0A);CIL A 451 (-4.0A);None; ZN A 401 ( 3.7A); ZN A 401 ( 2.2A)","1.36A","4aqlA-1ituA:5.9",null],["4C49_D_HCYD1384_1","CORTICOSTEROID-BINDING GLOBULIN","1itu","RENAL DIPEPTIDASE","Homo sapiens",5,"THR A 149;ARG A 229;ASN A 231;HIS A 152;TRP A 162","None;None;None;CIL A 451 (-4.0A);None","1.31A","4c49D-1ituA:0.0","4aqlA-1ituA:21.69"],["5DV4_A_NMYA601_2","CCR4-NOT TRANSCRIPTION COMPLEX SUBUNIT 6-LIKE","1itu","RENAL DIPEPTIDASE","Homo sapiens",3,"GLU A 125;TRP A 162;ASN A 250"," ZN A 401 ( 2.5A);None;CIL A 451 ( 4.7A)","0.58A","5dv4A-1ituA:0.6","4c49D-1ituA:22.68"],["6BTX_A_EDTA503_0","SOLUTE CARRIER FAMILY 39 (IRON-REGULATED TRANSPORTER)","1itu","RENAL DIPEPTIDASE","Homo sapiens",4,"TRP A  25;SER A  66;HIS A 152;GLY A 126","CIL A 451 ( 4.4A); ZN A 401 ( 3.7A);CIL A 451 (-4.0A);None","1.03A","6btxA-1ituA:undetectable","5dv4A-1ituA:22.12"]]