SIMILAR PATTERN OF AMINO ACIDS MAPPED TO 'CHL'


List of Similar Pattern of Amino Acids


Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IB4_A_ERMA2001_1
(CHIMERA PROTEIN OF
HUMAN
5-HYDROXYTRYPTAMINE
RECEPTOR 2B AND E.
COLI SOLUBLE
CYTOCHROME B562)
4xk8 CHLOROPHYLL A-B
BINDING PROTEIN P4,
CHLOROPLASTIC

(Pisum
sativum)
5 / 12 LEU 4 177
VAL 4 166
SER 4 165
LEU 4  96
VAL 4  97
CHL  4 615 ( 4.4A)
None
None
None
CLA  4 608 (-4.4A)
1.28A 4ib4A-4xk84:
undetectable
4ib4A-4xk84:
19.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N5D_A_SAMA306_1
(METHYLTRANSFERASE)
5zji CHLOROPHYLL A-B
BINDING PROTEIN,
CHLOROPLASTIC

(Zea
mays)
4 / 7 LEU 4 178
SER 4 166
ILE 4 155
ASP 4 160
CHL  4 618 ( 3.8A)
None
CHL  1 601 (-4.1A)
CHL  4 608 (-3.8A)
1.04A 5n5dA-5zji4:
undetectable
5n5dA-5zji4:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5O4Y_A_CCSA14_0
(PHE-MAA-ASN-PRO-HIS-
LEU-SER-TRP-SER-TRP-
9KK-9KK-ARG-CCS-GLY-
NH2)
5zji CHLOROPHYLL A-B
BINDING PROTEIN,
CHLOROPLASTIC

(Zea
mays)
4 / 6 PHE 4 190
ASN 4 191
ARG 4 157
GLY 4 184
CHL  4 608 (-4.1A)
LUT  4 619 (-3.1A)
CLA  4 609 ( 2.3A)
CHL  4 608 (-3.8A)
1.06A 5o4yA-5zji4:
undetectable
5o4yA-5zji4:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BEO_A_DHIA4_0
((DPR)PY(DHI)PKDL(DGN
))
5xno CHLOROPHYLL A-B
BINDING PROTEIN,
CHLOROPLASTIC

(Pisum
sativum)
3 / 3 TYR 3  33
PRO 3  42
LEU 3  45
CHL  3 601 (-4.6A)
None
CLA  3 602 (-4.0A)
0.95A 6beoA-5xno3:
undetectable
6beoA-5xno3:
11.11