SIMILAR PATTERN OF AMINO ACIDS MAPPED TO 'CEL'


List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2DXR_A_SORA1002_0
(LACTOTRANSFERRIN)		 4fim LACTOTRANSFERRIN
(Bos
taurus) 		3 / 3 THR A 430
PRO A 593
TYR A 660
 None
CEL  A 711 (-4.3A)
CEL  A 711 (-4.4A)
 0.16A 2dxrA-4fimA:
58.0		 2dxrA-4fimA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2ZMB_A_PXBA692_1
(LACTOTRANSFERRIN)		 4fim LACTOTRANSFERRIN
(Bos
taurus) 		3 / 3 PRO A 593
GLU A 659
TYR A 660
 CEL  A 711 (-4.3A)
ZN  A 703 ( 1.9A)
CEL  A 711 (-4.4A)
 0.09A 2zmbA-4fimA:
57.6		 2zmbA-4fimA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3CFL_A_5CHA693_1
(LACTOTRANSFERRIN)		 4fim LACTOTRANSFERRIN
(Bos
taurus) 		4 / 4 THR A 430
VAL A 591
GLY A 662
THR A 663
 None
None
CEL  A 711 (-3.3A)
None
 0.33A 3cflA-4fimA:
31.3		 3cflA-4fimA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3E9X_A_NIMA1_1
(LACTOTRANSFERRIN')		 4fim LACTOTRANSFERRIN
(Bos
taurus) 		4 / 4 GLU A 659
GLY A 662
THR A 663
GLU A 664
 ZN  A 703 ( 1.9A)
CEL  A 711 (-3.3A)
None
NAG  A 708 (-4.8A)
 0.82A 3e9xA-4fimA:
58.4		 3e9xA-4fimA:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ETE_C_H3PC552_1
(GLUTAMATE
DEHYDROGENASE)		 4fim LACTOTRANSFERRIN
(Bos
taurus) 		3 / 3 TYR A 665
TYR A 433
GLY A 396
 CEL  A 711 (-4.5A)
FE  A 701 ( 4.2A)
None
 0.74A 3eteB-4fimA:
undetectable
3eteD-4fimA:
undetectable
3eteF-4fimA:
undetectable		 3eteB-4fimA:
21.26
3eteD-4fimA:
21.26
3eteF-4fimA:
21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ETE_C_H3PC552_1
(GLUTAMATE
DEHYDROGENASE)		 4fim LACTOTRANSFERRIN
(Bos
taurus) 		3 / 3 TYR A 665
TYR A 433
GLY A 397
 CEL  A 711 (-4.5A)
FE  A 701 ( 4.2A)
None
 0.75A 3eteB-4fimA:
undetectable
3eteD-4fimA:
undetectable
3eteF-4fimA:
undetectable		 3eteB-4fimA:
21.26
3eteD-4fimA:
21.26
3eteF-4fimA:
21.26
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3IAZ_A_AINA1202_1
(LACTOTRANSFERRIN)		 4fim LACTOTRANSFERRIN
(Bos
taurus) 		3 / 3 GLU A 659
GLY A 662
THR A 663
 ZN  A 703 ( 1.9A)
CEL  A 711 (-3.3A)
None
 0.22A 3iazA-4fimA:
58.5		 3iazA-4fimA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3IB0_A_DIFA701_1
(LACTOTRANSFERRIN)		 4fim LACTOTRANSFERRIN
(Bos
taurus) 		4 / 4 PRO A 593
TYR A 660
GLY A 662
THR A 663
 CEL  A 711 (-4.3A)
CEL  A 711 (-4.4A)
CEL  A 711 (-3.3A)
None
 0.11A 3ib0A-4fimA:
60.1		 3ib0A-4fimA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3IB1_A_IMNA701_1
(LACTOTRANSFERRIN)		 4fim LACTOTRANSFERRIN
(Bos
taurus) 		4 / 4 PRO A 429
THR A 430
GLY A 662
THR A 663
 None
None
CEL  A 711 (-3.3A)
None
 0.44A 3ib1A-4fimA:
56.6		 3ib1A-4fimA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3IB2_A_IBPA3960_1
(LACTOTRANSFERRIN)		 4fim LACTOTRANSFERRIN
(Bos
taurus) 		4 / 4 GLY A 432
VAL A 591
GLY A 662
THR A 663
 CEL  A 711 (-3.7A)
None
CEL  A 711 (-3.3A)
None
 0.41A 3ib2A-4fimA:
58.0		 3ib2A-4fimA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3TAJ_A_NBOA700_1
(LACTOTRANSFERRIN)		 4fim LACTOTRANSFERRIN
(Bos
taurus) 		7 / 7 THR A 430
GLY A 432
PRO A 593
ASN A 594
TYR A 660
GLY A 662
THR A 663
 None
CEL  A 711 (-3.7A)
CEL  A 711 (-4.3A)
None
CEL  A 711 (-4.4A)
CEL  A 711 (-3.3A)
None
 0.35A 3tajA-4fimA:
60.1		 3tajA-4fimA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3U8Q_A_NPUA7231_1
(LACTOTRANSFERRIN)		 4fim LACTOTRANSFERRIN
(Bos
taurus) 		5 / 5 THR A 430
GLY A 432
PRO A 593
ASN A 594
TYR A 660
 None
CEL  A 711 (-3.7A)
CEL  A 711 (-4.3A)
None
CEL  A 711 (-4.4A)
 0.21A 3u8qA-4fimA:
60.7		 3u8qA-4fimA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4DXU_A_ACAA711_1
(LACTOTRANSFERRIN)		 4fim LACTOTRANSFERRIN
(Bos
taurus) 		6 / 6 GLY A 432
VAL A 591
PRO A 593
GLY A 662
GLU A 664
TYR A 665
 CEL  A 711 (-3.7A)
None
CEL  A 711 (-4.3A)
CEL  A 711 (-3.3A)
NAG  A 708 (-4.8A)
CEL  A 711 (-4.5A)
 0.37A 4dxuA-4fimA:
61.0		 4dxuA-4fimA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4FJP_A_NPSA711_1
(LACTOTRANSFERRIN)		 4fim LACTOTRANSFERRIN
(Bos
taurus) 		6 / 6 THR A 430
GLY A 432
PRO A 593
ASN A 594
TYR A 660
GLY A 662
 None
CEL  A 711 (-3.7A)
CEL  A 711 (-4.3A)
None
CEL  A 711 (-4.4A)
CEL  A 711 (-3.3A)
 0.19A 4fjpA-4fimA:
61.2		 4fjpA-4fimA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4FOR_A_FLPA711_1
(LACTOTRANSFERRIN)		 4fim LACTOTRANSFERRIN
(Bos
taurus) 		7 / 7 THR A 430
GLY A 432
VAL A 591
PRO A 593
ASN A 594
TYR A 660
GLY A 662
 None
CEL  A 711 (-3.7A)
None
CEL  A 711 (-4.3A)
None
CEL  A 711 (-4.4A)
CEL  A 711 (-3.3A)
 0.08A 4forA-4fimA:
61.0		 4forA-4fimA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4G2Z_A_ID8A711_1
(LACTOTRANSFERRIN)		 4fim LACTOTRANSFERRIN
(Bos
taurus) 		3 / 3 PRO A 593
TYR A 660
GLY A 662
 CEL  A 711 (-4.3A)
CEL  A 711 (-4.4A)
CEL  A 711 (-3.3A)
 0.04A 4g2zA-4fimA:
61.4		 4g2zA-4fimA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4G77_A_TLFA711_0
(LACTOTRANSFERRIN)		 4fim LACTOTRANSFERRIN
(Bos
taurus) 		7 / 7 ILE A 469
LEU A 473
HIS A 588
ALA A 590
VAL A 591
TYR A 665
ALA A 668
 None
NAG  A 707 ( 4.7A)
ZN  A 704 (-3.2A)
None
None
CEL  A 711 (-4.5A)
NAG  A 707 ( 3.8A)
 0.08A 4g77A-4fimA:
60.9		 4g77A-4fimA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4GRK_A_KTRA713_1
(LACTOTRANSFERRIN)		 4fim LACTOTRANSFERRIN
(Bos
taurus) 		5 / 5 THR A 430
GLY A 432
VAL A 591
PRO A 593
TYR A 660
 None
CEL  A 711 (-3.7A)
None
CEL  A 711 (-4.3A)
CEL  A 711 (-4.4A)
 0.15A 4grkA-4fimA:
60.7		 4grkA-4fimA:
100.00