SIMILAR PATTERN OF AMINO ACIDS MAPPED TO 'CEG'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1F9G_A_ASCA950_0 (HYALURONATE LYASE)	1j0n	XANTHAN LYASE (Bacillus sp. GL1)	6 / 7	ASN A 146 TRP A 148 TYR A 255 ARG A 309 ARG A 313 ASN A 424	None CEG A 780 (-3.6A) CEG A 780 (-4.4A) CEG A 780 (-3.6A) CEG A 780 (-2.9A) None	0.74A	1f9gA-1j0nA: 47.8	1f9gA-1j0nA: 30.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2BM9_A_SAMA301_0 (CEPHALOSPORIN HYDROXYLASE CMCI)	1j0n	XANTHAN LYASE (Bacillus sp. GL1)	5 / 12	LEU A 131 GLU A 98 SER A 157 ASP A 70 ALA A 83	None CEG A 780 ( 4.9A) None None None	1.13A	2bm9A-1j0nA: undetectable	2bm9A-1j0nA: 13.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2BM9_B_SAMB301_0 (CEPHALOSPORIN HYDROXYLASE CMCI)	1j0n	XANTHAN LYASE (Bacillus sp. GL1)	5 / 12	LEU A 131 GLU A 98 SER A 157 ASP A 70 ALA A 83	None CEG A 780 ( 4.9A) None None None	1.29A	2bm9B-1j0nA: undetectable	2bm9B-1j0nA: 13.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4YSH_B_GLYB402_0 (GLYCINE OXIDASE)	1j0n	XANTHAN LYASE (Bacillus sp. GL1)	4 / 5	GLU A 421 TYR A 255 ARG A 313 ARG A 309	None CEG A 780 (-4.4A) CEG A 780 (-2.9A) CEG A 780 (-3.6A)	1.30A	4yshB-1j0nA: 0.0	4yshB-1j0nA: 20.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5X7P_A_ACRA1481_1 (GLYCOSIDE HYDROLASE FAMILY 31 ALPHA-GLUCOSIDASE)	1j0n	XANTHAN LYASE (Bacillus sp. GL1)	4 / 6	TRP A 199 SER A 258 GLU A 310 TYR A 255	None CEG A 780 ( 4.7A) CEG A 780 ( 4.3A) CEG A 780 (-4.4A)	1.34A	5x7pA-1j0nA: 5.3	5x7pA-1j0nA: 21.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5X7P_B_ACRB1481_1 (GLYCOSIDE HYDROLASE FAMILY 31 ALPHA-GLUCOSIDASE)	1j0n	XANTHAN LYASE (Bacillus sp. GL1)	4 / 6	TRP A 199 SER A 258 GLU A 310 TYR A 255	None CEG A 780 ( 4.7A) CEG A 780 ( 4.3A) CEG A 780 (-4.4A)	1.32A	5x7pB-1j0nA: 5.2	5x7pB-1j0nA: 21.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5X7Q_A_ACRA1481_1 (GLYCOSIDE HYDROLASE FAMILY 31 ALPHA-GLUCOSIDASE)	1j0n	XANTHAN LYASE (Bacillus sp. GL1)	4 / 6	TRP A 199 SER A 258 GLU A 310 TYR A 255	None CEG A 780 ( 4.7A) CEG A 780 ( 4.3A) CEG A 780 (-4.4A)	1.32A	5x7qA-1j0nA: 3.8	5x7qA-1j0nA: 21.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5X7Q_B_ACRB1481_1 (GLYCOSIDE HYDROLASE FAMILY 31 ALPHA-GLUCOSIDASE)	1j0n	XANTHAN LYASE (Bacillus sp. GL1)	4 / 6	TRP A 199 SER A 258 GLU A 310 TYR A 255	None CEG A 780 ( 4.7A) CEG A 780 ( 4.3A) CEG A 780 (-4.4A)	1.31A	5x7qB-1j0nA: 6.2	5x7qB-1j0nA: 21.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5X7R_A_ACRA1481_1 (GLYCOSIDE HYDROLASE FAMILY 31 ALPHA-GLUCOSIDASE)	1j0n	XANTHAN LYASE (Bacillus sp. GL1)	4 / 6	TRP A 199 SER A 258 GLU A 310 TYR A 255	None CEG A 780 ( 4.7A) CEG A 780 ( 4.3A) CEG A 780 (-4.4A)	1.33A	5x7rA-1j0nA: 3.6	5x7rA-1j0nA: 21.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5X7R_B_ACRB1481_1 (GLYCOSIDE HYDROLASE FAMILY 31 ALPHA-GLUCOSIDASE)	1j0n	XANTHAN LYASE (Bacillus sp. GL1)	4 / 6	TRP A 199 SER A 258 GLU A 310 TYR A 255	None CEG A 780 ( 4.7A) CEG A 780 ( 4.3A) CEG A 780 (-4.4A)	1.30A	5x7rB-1j0nA: 5.8	5x7rB-1j0nA: 21.21

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1F9G_A_ASCA950_0","HYALURONATE LYASE","1j0n","XANTHAN LYASE","Bacillus sp. GL1",6,"ASN A 146;TRP A 148;TYR A 255;ARG A 309;ARG A 313;ASN A 424","None;CEG A 780 (-3.6A);CEG A 780 (-4.4A);CEG A 780 (-3.6A);CEG A 780 (-2.9A);None","0.74A","1f9gA-1j0nA:47.8",null],["2BM9_A_SAMA301_0","CEPHALOSPORIN HYDROXYLASE CMCI","1j0n","XANTHAN LYASE","Bacillus sp. GL1",5,"LEU A 131;GLU A  98;SER A 157;ASP A  70;ALA A  83","None;CEG A 780 ( 4.9A);None;None;None","1.13A","2bm9A-1j0nA:undetectable","1f9gA-1j0nA:30.50"],["2BM9_B_SAMB301_0","CEPHALOSPORIN HYDROXYLASE CMCI","1j0n","XANTHAN LYASE","Bacillus sp. GL1",5,"LEU A 131;GLU A  98;SER A 157;ASP A  70;ALA A  83","None;CEG A 780 ( 4.9A);None;None;None","1.29A","2bm9B-1j0nA:undetectable","2bm9A-1j0nA:13.72"],["4YSH_B_GLYB402_0","GLYCINE OXIDASE","1j0n","XANTHAN LYASE","Bacillus sp. GL1",4,"GLU A 421;TYR A 255;ARG A 313;ARG A 309","None;CEG A 780 (-4.4A);CEG A 780 (-2.9A);CEG A 780 (-3.6A)","1.30A","4yshB-1j0nA:0.0","2bm9B-1j0nA:13.72"],["5X7P_A_ACRA1481_1","GLYCOSIDE HYDROLASE FAMILY 31 ALPHA-GLUCOSIDASE","1j0n","XANTHAN LYASE","Bacillus sp. GL1",4,"TRP A 199;SER A 258;GLU A 310;TYR A 255","None;CEG A 780 ( 4.7A);CEG A 780 ( 4.3A);CEG A 780 (-4.4A)","1.34A","5x7pA-1j0nA:5.3","4yshB-1j0nA:20.29"],["5X7P_B_ACRB1481_1","GLYCOSIDE HYDROLASE FAMILY 31 ALPHA-GLUCOSIDASE","1j0n","XANTHAN LYASE","Bacillus sp. GL1",4,"TRP A 199;SER A 258;GLU A 310;TYR A 255","None;CEG A 780 ( 4.7A);CEG A 780 ( 4.3A);CEG A 780 (-4.4A)","1.32A","5x7pB-1j0nA:5.2","5x7pA-1j0nA:21.21"],["5X7Q_A_ACRA1481_1","GLYCOSIDE HYDROLASE FAMILY 31 ALPHA-GLUCOSIDASE","1j0n","XANTHAN LYASE","Bacillus sp. GL1",4,"TRP A 199;SER A 258;GLU A 310;TYR A 255","None;CEG A 780 ( 4.7A);CEG A 780 ( 4.3A);CEG A 780 (-4.4A)","1.32A","5x7qA-1j0nA:3.8","5x7pB-1j0nA:21.21"],["5X7Q_B_ACRB1481_1","GLYCOSIDE HYDROLASE FAMILY 31 ALPHA-GLUCOSIDASE","1j0n","XANTHAN LYASE","Bacillus sp. GL1",4,"TRP A 199;SER A 258;GLU A 310;TYR A 255","None;CEG A 780 ( 4.7A);CEG A 780 ( 4.3A);CEG A 780 (-4.4A)","1.31A","5x7qB-1j0nA:6.2","5x7qA-1j0nA:21.21"],["5X7R_A_ACRA1481_1","GLYCOSIDE HYDROLASE FAMILY 31 ALPHA-GLUCOSIDASE","1j0n","XANTHAN LYASE","Bacillus sp. GL1",4,"TRP A 199;SER A 258;GLU A 310;TYR A 255","None;CEG A 780 ( 4.7A);CEG A 780 ( 4.3A);CEG A 780 (-4.4A)","1.33A","5x7rA-1j0nA:3.6","5x7qB-1j0nA:21.21"],["5X7R_B_ACRB1481_1","GLYCOSIDE HYDROLASE FAMILY 31 ALPHA-GLUCOSIDASE","1j0n","XANTHAN LYASE","Bacillus sp. GL1",4,"TRP A 199;SER A 258;GLU A 310;TYR A 255","None;CEG A 780 ( 4.7A);CEG A 780 ( 4.3A);CEG A 780 (-4.4A)","1.30A","5x7rB-1j0nA:5.8","5x7rA-1j0nA:21.21"]]