SIMILAR PATTERN OF AMINO ACIDS MAPPED TO 'CE6'

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)	View	Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1DY4_A_SNPA437_1 (EXOGLUCANASE 1)	4xeb	GLUCANASE (Talaromyces funiculosus)	12 / 12	ALA A 140 TYR A 142 TYR A 168 ASP A 170 SER A 171 GLN A 172 GLU A 209 ASP A 211 GLU A 214 THR A 243 ARG A 248 ASP A 373	CE6  A 505 ( 4.7A) CE6  A 505 (-4.3A) None K  A 506 (-3.2A) K  A 506 ( 4.8A) CBI  A 504 (-4.4A) K  A 506 (-2.6A) K  A 506 ( 4.7A) CBI  A 504 ( 4.4A) CBI  A 504 (-3.1A) CBI  A 504 (-2.8A) None	0.30A	1dy4A-4xebA: 64.9	1dy4A-4xebA: 64.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2HA4_B_ACHB603_0 (ACETYLCHOLINESTERASE)	4jjj	CELLULOSE 1,4-BETA-CELLOBIOSID ASE (Thermobifida fusca)	4 / 7	TYR A 300 GLU A 108 TYR A 385 GLY A 383	CE6  A 703 (-3.8A) CE6  A 703 ( 4.5A) None None	1.21A	2ha4B-4jjjA: undetectable	2ha4B-4jjjA: 23.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2PH9_A_GNTA301_1 (SOLUBLE ACETYLCHOLINE RECEPTOR)	4jjj	CELLULOSE 1,4-BETA-CELLOBIOSID ASE (Thermobifida fusca)	4 / 7	TYR A 105 GLN A 109 TYR A 115 ILE A 317	None None None CE6  A 703 (-4.8A)	1.30A	2ph9A-4jjjA: undetectable 2ph9B-4jjjA: undetectable	2ph9A-4jjjA: 16.64 2ph9B-4jjjA: 16.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3JQA_A_DX4A270_0 (PTERIDINE REDUCTASE 1)	4xeb	GLUCANASE (Talaromyces funiculosus)	4 / 6	SER A 369 ASP A 211 TYR A 142 PRO A 174	CE6  A 505 (-2.7A) K  A 506 ( 4.7A) CE6  A 505 (-4.3A) None	1.48A	3jqaA-4xebA: undetectable	3jqaA-4xebA: 21.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3JQA_B_DX4B270_0 (PTERIDINE REDUCTASE 1)	4xeb	GLUCANASE (Talaromyces funiculosus)	4 / 6	SER A 369 ASP A 211 TYR A 142 PRO A 174	CE6  A 505 (-2.7A) K  A 506 ( 4.7A) CE6  A 505 (-4.3A) None	1.46A	3jqaB-4xebA: undetectable	3jqaB-4xebA: 21.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3JQA_D_DX4D270_0 (PTERIDINE REDUCTASE 1)	4xeb	GLUCANASE (Talaromyces funiculosus)	4 / 6	SER A 369 ASP A 211 TYR A 142 PRO A 174	CE6  A 505 (-2.7A) K  A 506 ( 4.7A) CE6  A 505 (-4.3A) None	1.46A	3jqaD-4xebA: undetectable	3jqaD-4xebA: 21.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3TWP_D_SALD404_1 (ANTHRANILATE PHOSPHORIBOSYLTRANSF ERASE)	4jjj	CELLULOSE 1,4-BETA-CELLOBIOSID ASE (Thermobifida fusca)	4 / 5	ASN A 221 ALA A 222 PRO A 223 ALA A 227	None CE6  A 703 ( 4.1A) None None	1.30A	3twpD-4jjjA: undetectable	3twpD-4jjjA: 21.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3WIP_F_ACHF301_0 (ACETYLCHOLINE-BINDIN G PROTEIN)	4xeb	GLUCANASE (Talaromyces funiculosus)	4 / 7	TYR A 142 THR A 105 TYR A 168 TYR A 106	CE6  A 505 (-4.3A) None None None	1.49A	3wipF-4xebA: undetectable 3wipG-4xebA: undetectable	3wipF-4xebA: 18.69 3wipG-4xebA: 18.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4E7C_A_ACTA504_0 (UDP-N-ACETYLGLUCOSAM INE 1-CARBOXYVINYLTRANSF ERASE)	4jjj	CELLULOSE 1,4-BETA-CELLOBIOSID ASE (Thermobifida fusca)	3 / 3	ARG A 316 TRP A 315 GLY A 304	None CE6  A 703 (-3.6A) None	1.00A	4e7cA-4jjjA: undetectable	4e7cA-4jjjA: 20.98
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4IPM_A_ACTA503_0 (GH7 FAMILY PROTEIN)	4xeb	GLUCANASE (Talaromyces funiculosus)	9 / 9	ASN A 138 ALA A 140 TYR A 142 TYR A 168 ASP A 170 GLU A 209 ASP A 211 GLU A 214 TRP A 371	None CE6  A 505 ( 4.7A) CE6  A 505 (-4.3A) None K  A 506 (-3.2A) K  A 506 (-2.6A) K  A 506 ( 4.7A) CBI  A 504 ( 4.4A) CE6  A 505 (-3.7A)	0.49A	4ipmA-4xebA: 62.3	4ipmA-4xebA: 52.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4QTU_B_SAMB301_1 (PUTATIVE METHYLTRANSFERASE BUD23)	4xeb	GLUCANASE (Talaromyces funiculosus)	4 / 5	TYR A 168 SER A 369 ASP A 211 ASP A 259	None CE6  A 505 (-2.7A) K  A 506 ( 4.7A) CL  A 510 (-3.4A)	1.10A	4qtuB-4xebA: undetectable	4qtuB-4xebA: 18.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5X66_C_MTXC402_1 (THYMIDYLATE SYNTHASE)	4xeb	GLUCANASE (Talaromyces funiculosus)	5 / 9	ILE A  84 LEU A 370 GLY A 102 ASN A 100 ALA A 140	None None None CE6  A 505 (-3.6A) CE6  A 505 ( 4.7A)	1.37A	5x66C-4xebA: undetectable	5x66C-4xebA: 18.37