SIMILAR PATTERN OF AMINO ACIDS MAPPED TO 'CDM'


List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AEG_A_4APA296_1
(CYTOCHROME C
PEROXIDASE)		 1oj4 4-DIPHOSPHOCYTIDYL-2
-C-METHYL-D-ERYTHRIT
OL KINASE
(Escherichia
coli) 		4 / 8 GLY A 241
THR A 181
GLY A 101
ASP A 141
 None
CDM  A1284 (-3.6A)
ANP  A1285 (-2.9A)
CDM  A1284 (-2.9A)
 0.78A 1aegA-1oj4A:
undetectable		 1aegA-1oj4A:
21.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JHQ_A_NIOA991_1
(NICOTINATE
MONONUCLEOTIDE:5,6-D
IMETHYLBENZIMIDAZOLE
PHOSPHORIBOSYLTRANSF
ERASE)		 1oj4 4-DIPHOSPHOCYTIDYL-2
-C-METHYL-D-ERYTHRIT
OL KINASE
(Escherichia
coli) 		5 / 8 THR A 238
GLY A 239
GLY A 106
LEU A 104
GLY A 101
 None
CDM  A1284 ( 4.2A)
ANP  A1285 (-4.1A)
None
ANP  A1285 (-2.9A)
 1.40A 1jhqA-1oj4A:
undetectable		 1jhqA-1oj4A:
23.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JHV_A_NIOA991_1
(NICOTINATE
MONONUCLEOTIDE:5,6-D
IMETHYLBENZIMIDAZOLE
PHOSPHORIBOSYLTRANSF
ERASE)		 1oj4 4-DIPHOSPHOCYTIDYL-2
-C-METHYL-D-ERYTHRIT
OL KINASE
(Escherichia
coli) 		5 / 8 THR A 238
GLY A 239
GLY A 106
LEU A 104
GLY A 101
 None
CDM  A1284 ( 4.2A)
ANP  A1285 (-4.1A)
None
ANP  A1285 (-2.9A)
 1.37A 1jhvA-1oj4A:
undetectable		 1jhvA-1oj4A:
23.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P2K_C_SAMC6735_1
(16S RRNA METHYLASE)		 1oj4 4-DIPHOSPHOCYTIDYL-2
-C-METHYL-D-ERYTHRIT
OL KINASE
(Escherichia
coli) 		4 / 5 ASN A 110
ASP A 141
THR A 240
SER A   7
 ANP  A1285 (-3.7A)
CDM  A1284 (-2.9A)
CDM  A1284 ( 4.8A)
None
 1.46A 3p2kC-1oj4A:
undetectable		 3p2kC-1oj4A:
23.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SXJ_A_SAMA258_0
(PUTATIVE
METHYLTRANSFERASE)		 1oj4 4-DIPHOSPHOCYTIDYL-2
-C-METHYL-D-ERYTHRIT
OL KINASE
(Escherichia
coli) 		5 / 12 GLY A 241
GLY A 239
SER A 178
GLU A 212
ALA A 215
 None
CDM  A1284 ( 4.2A)
None
None
None
 1.22A 3sxjA-1oj4A:
undetectable		 3sxjA-1oj4A:
23.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SXJ_B_SAMB258_0
(PUTATIVE
METHYLTRANSFERASE)		 1oj4 4-DIPHOSPHOCYTIDYL-2
-C-METHYL-D-ERYTHRIT
OL KINASE
(Escherichia
coli) 		5 / 12 GLY A 241
GLY A 239
SER A 178
GLU A 212
ALA A 215
 None
CDM  A1284 ( 4.2A)
None
None
None
 1.23A 3sxjB-1oj4A:
undetectable		 3sxjB-1oj4A:
23.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NJH_A_SAMA302_0
(7-CARBOXY-7-DEAZAGUA
NINE SYNTHASE)		 3q80 2-C-METHYL-D-ERYTHRI
TOL 4-PHOSPHATE
CYTIDYLTRANSFERASE
(Mycobacterium
tuberculosis) 		5 / 12 GLU A 198
ASP A 192
THR A 191
VAL A 133
ASP A 193
 None
None
CDM  A 500 (-4.4A)
None
None
 1.33A 4njhA-3q80A:
0.2		 4njhA-3q80A:
25.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UBE_A_2FAA401_2
(ADENOSINE KINASE)		 3q80 2-C-METHYL-D-ERYTHRI
TOL 4-PHOSPHATE
CYTIDYLTRANSFERASE
(Mycobacterium
tuberculosis) 		4 / 4 ALA A 108
VAL A  56
GLY A  79
THR A  86
 CDM  A 500 (-3.8A)
None
None
CDM  A 500 (-3.2A)
 0.88A 4ubeA-3q80A:
undetectable		 4ubeA-3q80A:
25.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GTQ_A_ACTA204_0
(N-ACETYLTRANSFERASE)		 1oj4 4-DIPHOSPHOCYTIDYL-2
-C-METHYL-D-ERYTHRIT
OL KINASE
(Escherichia
coli) 		4 / 5 THR A 240
CYH A 243
THR A 238
GLY A 239
 CDM  A1284 ( 4.8A)
None
None
CDM  A1284 ( 4.2A)
 1.27A 6gtqA-1oj4A:
1.9		 6gtqA-1oj4A:
21.33