SIMILAR PATTERN OF AMINO ACIDS MAPPED TO 'CDF'


List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M0O_A_EPAA502_1
(TERMINAL
OLEFIN-FORMING FATTY
ACID DECARBOXYLASE)		 2vsi 2-C-METHYL-D-ERYTHRI
TOL 4-PHOSPHATE
CYTIDYLYLTRANSFERASE
(Streptococcus
pneumoniae) 		5 / 10 LEU A   7
ARG A  85
ALA A 196
PHE A 173
VAL A 108
 CDF  A1234 (-3.8A)
CDF  A1234 (-3.5A)
None
None
None
 1.35A 5m0oA-2vsiA:
undetectable		 5m0oA-2vsiA:
20.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M0O_C_EPAC502_1
(TERMINAL
OLEFIN-FORMING FATTY
ACID DECARBOXYLASE)		 2vsi 2-C-METHYL-D-ERYTHRI
TOL 4-PHOSPHATE
CYTIDYLYLTRANSFERASE
(Streptococcus
pneumoniae) 		4 / 8 LEU A   7
ARG A  85
ALA A 196
PHE A 173
 CDF  A1234 (-3.8A)
CDF  A1234 (-3.5A)
None
None
 0.83A 5m0oC-2vsiA:
undetectable		 5m0oC-2vsiA:
20.79