SIMILAR PATTERN OF AMINO ACIDS MAPPED TO 'CCX'
DrReposER ID / Desc. | Hit PDBID |
Hit Macromolecule |
Res. Matches |
Interface | HETATM | RMSD | Dali Z-score |
Seq. Identity (%) |
View | Dock | |
---|---|---|---|---|---|---|---|---|---|---|---|
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1OPJ_B_STIB4_2 (PROTO-ONCOGENETYROSINE-PROTEINKINASE ABL1) |
3lw0 | INSULIN-LIKE GROWTHFACTOR 1 RECEPTOR (Homosapiens) | 4 / 6 | LEU A1005LYS A1033VAL A1053MET A1082 | NoneCCX A 1 ( 3.7A)NoneNone | 0.88A | 1opjB-3lw0A:31.7 | 1opjB-3lw0A:44.20 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 1XBB_A_STIA1_1 (TYROSINE-PROTEINKINASE SYK) |
3lw0 | INSULIN-LIKE GROWTHFACTOR 1 RECEPTOR (Homosapiens) | 5 / 9 | LEU A1005VAL A1013ALA A1031MET A1079GLY A1085 | NoneNoneNoneCCX A 1 ( 3.9A)None | 0.41A | 1xbbA-3lw0A:29.3 | 1xbbA-3lw0A:33.55 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2HYY_D_STID600_2 (PROTO-ONCOGENETYROSINE-PROTEINKINASE ABL1) |
3lw0 | INSULIN-LIKE GROWTHFACTOR 1 RECEPTOR (Homosapiens) | 4 / 4 | LEU A1005LYS A1033VAL A1063MET A1082 | NoneCCX A 1 ( 3.7A)CCX A 1 (-4.1A)None | 0.84A | 2hyyD-3lw0A:32.5 | 2hyyD-3lw0A:44.77 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2WGJ_A_VGHA2346_1 (HEPATOCYTE GROWTHFACTOR RECEPTOR) |
3lw0 | INSULIN-LIKE GROWTHFACTOR 1 RECEPTOR (Homosapiens) | 7 / 12 | GLY A1006VAL A1013ALA A1031MET A1082GLY A1085MET A1142ASP A1153 | NoneNoneNoneNoneNoneNoneCCX A 1 ( 4.3A) | 1.06A | 2wgjA-3lw0A:32.7 | 2wgjA-3lw0A:37.74 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2XP2_A_VGHA9000_1 (TYROSINE-PROTEINKINASE RECEPTOR) |
3lw0 | INSULIN-LIKE GROWTHFACTOR 1 RECEPTOR (Homosapiens) | 6 / 9 | LEU A1005VAL A1013ALA A1031MET A1082GLY A1085GLY A1152 | NoneNoneNoneNoneNoneCCX A 1 (-3.6A) | 0.51A | 2xp2A-3lw0A:30.1 | 2xp2A-3lw0A:41.35 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 2XP2_A_VGHA9000_1 (TYROSINE-PROTEINKINASE RECEPTOR) |
3lw0 | INSULIN-LIKE GROWTHFACTOR 1 RECEPTOR (Homosapiens) | 6 / 9 | LEU A1005VAL A1013ALA A1031MET A1082GLY A1152ASP A1153 | NoneNoneNoneNoneCCX A 1 (-3.6A)CCX A 1 ( 4.3A) | 0.79A | 2xp2A-3lw0A:30.1 | 2xp2A-3lw0A:41.35 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2YVL_B_SAMB602_1 (HYPOTHETICAL PROTEIN) |
3lw0 | INSULIN-LIKE GROWTHFACTOR 1 RECEPTOR (Homosapiens) | 3 / 3 | GLU A1050ASP A1135TYR A1165 | CCX A 1 ( 4.3A)NoneNone | 0.77A | 2yvlB-3lw0A:undetectable | 2yvlB-3lw0A:22.84 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3AOX_A_EMHA901_1 (ALK TYROSINE KINASERECEPTOR) |
3lw0 | INSULIN-LIKE GROWTHFACTOR 1 RECEPTOR (Homosapiens) | 7 / 10 | ARG A1003LEU A1005ALA A1031VAL A1063LEU A1081MET A1082GLY A1085 | NoneNoneNoneCCX A 1 (-4.1A)NoneNoneNone | 0.54A | 3aoxA-3lw0A:29.4 | 3aoxA-3lw0A:39.39 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3CS9_D_NILD600_1 (PROTO-ONCOGENETYROSINE-PROTEINKINASE ABL1) |
3lw0 | INSULIN-LIKE GROWTHFACTOR 1 RECEPTOR (Homosapiens) | 5 / 12 | ALA A1031VAL A1053GLY A1085PHE A1131HIS A1133 | NoneNoneNoneNoneCCX A 1 (-4.0A) | 0.58A | 3cs9D-3lw0A:31.7 | 3cs9D-3lw0A:44.81 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3GP0_A_NILA1_2 (MITOGEN-ACTIVATEDPROTEIN KINASE 11) |
3lw0 | INSULIN-LIKE GROWTHFACTOR 1 RECEPTOR (Homosapiens) | 4 / 7 | LYS A1033VAL A1062LEU A1081ILE A1151 | CCX A 1 ( 3.7A)NoneNoneNone | 0.94A | 3gp0A-3lw0A:22.8 | 3gp0A-3lw0A:23.18 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3JQ7_C_DX2C270_1 (PTERIDINE REDUCTASE1) |
3lw0 | INSULIN-LIKE GROWTHFACTOR 1 RECEPTOR (Homosapiens) | 4 / 8 | PHE A1189ASP A1135VAL A1176LEU A1184 | CCX A 1 ( 4.4A)NoneNoneNone | 1.10A | 3jq7C-3lw0A:undetectable | 3jq7C-3lw0A:21.16 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3SM2_A_478A126_2 (GAG-PRO-POLPOLYPROTEIN) |
3lw0 | INSULIN-LIKE GROWTHFACTOR 1 RECEPTOR (Homosapiens) | 5 / 11 | ALA A1138VAL A1149ALA A1116PRO A1107LEU A1091 | NoneNoneNoneCCX A1287 ( 4.8A)None | 1.04A | 3sm2B-3lw0A:undetectable | 3sm2B-3lw0A:18.09 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3UE4_A_DB8A601_1 (TYROSINE-PROTEINKINASE ABL1) |
3lw0 | INSULIN-LIKE GROWTHFACTOR 1 RECEPTOR (Homosapiens) | 7 / 12 | LEU A1005ALA A1031LYS A1033GLU A1050VAL A1063MET A1082GLY A1085 | NoneNoneCCX A 1 ( 3.7A)CCX A 1 ( 4.3A)CCX A 1 (-4.1A)NoneNone | 1.01A | 3ue4A-3lw0A:30.4 | 3ue4A-3lw0A:43.53 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3UG2_A_IREA1_1 (EPIDERMAL GROWTHFACTOR RECEPTOR) |
3lw0 | INSULIN-LIKE GROWTHFACTOR 1 RECEPTOR (Homosapiens) | 7 / 12 | LEU A1005VAL A1013ALA A1031LYS A1033LEU A1081MET A1082GLY A1085 | NoneNoneNoneCCX A 1 ( 3.7A)NoneNoneNone | 0.73A | 3ug2A-3lw0A:28.2 | 3ug2A-3lw0A:32.29 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3UG2_A_IREA1_1 (EPIDERMAL GROWTHFACTOR RECEPTOR) |
3lw0 | INSULIN-LIKE GROWTHFACTOR 1 RECEPTOR (Homosapiens) | 7 / 12 | LEU A1005VAL A1013ALA A1031MET A1079LEU A1081MET A1082GLY A1085 | NoneNoneNoneCCX A 1 ( 3.9A)NoneNoneNone | 0.52A | 3ug2A-3lw0A:28.2 | 3ug2A-3lw0A:32.29 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 3ZBF_A_VGHA3000_1 (PROTO-ONCOGENETYROSINE-PROTEINKINASE ROS) |
3lw0 | INSULIN-LIKE GROWTHFACTOR 1 RECEPTOR (Homosapiens) | 6 / 12 | ALA A1031LEU A1081MET A1082GLY A1085ASP A1086GLY A1152 | NoneNoneNoneNoneNoneCCX A 1 (-3.6A) | 0.39A | 3zbfA-3lw0A:30.6 | 3zbfA-3lw0A:44.98 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4ANS_A_VGHA9000_1 (ALK TYROSINE KINASERECEPTOR) |
3lw0 | INSULIN-LIKE GROWTHFACTOR 1 RECEPTOR (Homosapiens) | 6 / 9 | LEU A1005VAL A1013ALA A1031MET A1079MET A1082GLY A1085 | NoneNoneNoneCCX A 1 ( 3.9A)NoneNone | 0.45A | 4ansA-3lw0A:29.9 | 4ansA-3lw0A:39.89 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4L9I_A_8PRA601_1 (RHODOPSIN KINASE) |
3lw0 | INSULIN-LIKE GROWTHFACTOR 1 RECEPTOR (Homosapiens) | 4 / 7 | ALA A1031MET A1079MET A1082ASP A1086 | NoneCCX A 1 ( 3.9A)NoneNone | 0.70A | 4l9iA-3lw0A:8.3 | 4l9iA-3lw0A:20.74 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4L9I_A_8PRA601_1 (RHODOPSIN KINASE) |
3lw0 | INSULIN-LIKE GROWTHFACTOR 1 RECEPTOR (Homosapiens) | 4 / 7 | VAL A1013ALA A1031MET A1079ASP A1086 | NoneNoneCCX A 1 ( 3.9A)None | 0.73A | 4l9iA-3lw0A:8.3 | 4l9iA-3lw0A:20.74 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4MKC_A_4MKA1503_1 (ALK TYROSINE KINASERECEPTOR) |
3lw0 | INSULIN-LIKE GROWTHFACTOR 1 RECEPTOR (Homosapiens) | 9 / 12 | LEU A1005GLY A1008VAL A1013ALA A1031LYS A1033LEU A1081GLY A1085ASP A1086SER A1089 | NoneNoneNoneNoneCCX A 1 ( 3.7A)NoneNoneNoneNone | 0.70A | 4mkcA-3lw0A:30.4 | 4mkcA-3lw0A:37.33 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4MXX_B_DB8B601_1 (PROTO-ONCOGENETYROSINE-PROTEINKINASE SRC) |
3lw0 | INSULIN-LIKE GROWTHFACTOR 1 RECEPTOR (Homosapiens) | 7 / 12 | LEU A1005VAL A1013ALA A1031LYS A1033VAL A1063MET A1082GLY A1085 | NoneNoneNoneCCX A 1 ( 3.7A)CCX A 1 (-4.1A)NoneNone | 0.80A | 4mxxB-3lw0A:29.2 | 4mxxB-3lw0A:36.62 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4WBO_C_ANWC601_0 (RHODOPSIN KINASE) |
3lw0 | INSULIN-LIKE GROWTHFACTOR 1 RECEPTOR (Homosapiens) | 5 / 6 | ARG A1003LEU A1005ALA A1031MET A1079MET A1082 | NoneNoneNoneCCX A 1 ( 3.9A)None | 0.61A | 4wboC-3lw0A:22.4 | 4wboC-3lw0A:21.44 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5AAA_A_VGHA9000_1 (ALK TYROSINE KINASERECEPTOR) |
3lw0 | INSULIN-LIKE GROWTHFACTOR 1 RECEPTOR (Homosapiens) | 7 / 9 | LEU A1005VAL A1013ALA A1031MET A1082GLY A1085GLY A1152ASP A1153 | NoneNoneNoneNoneNoneCCX A 1 (-3.6A)CCX A 1 ( 4.3A) | 0.68A | 5aaaA-3lw0A:30.4 | 5aaaA-3lw0A:41.06 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5AAB_A_VGHA9000_1 (ALK TYROSINE KINASERECEPTOR) |
3lw0 | INSULIN-LIKE GROWTHFACTOR 1 RECEPTOR (Homosapiens) | 7 / 10 | LEU A1005VAL A1013ALA A1031LYS A1033MET A1082GLY A1085GLY A1152 | NoneNoneNoneCCX A 1 ( 3.7A)NoneNoneCCX A 1 (-3.6A) | 0.79A | 5aabA-3lw0A:30.2 | 5aabA-3lw0A:41.06 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5AAB_A_VGHA9000_1 (ALK TYROSINE KINASERECEPTOR) |
3lw0 | INSULIN-LIKE GROWTHFACTOR 1 RECEPTOR (Homosapiens) | 7 / 10 | LEU A1005VAL A1013ALA A1031LYS A1033MET A1082GLY A1152ASP A1153 | NoneNoneNoneCCX A 1 ( 3.7A)NoneCCX A 1 (-3.6A)CCX A 1 ( 4.3A) | 1.01A | 5aabA-3lw0A:30.2 | 5aabA-3lw0A:41.06 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5AAC_A_VGHA9000_1 (ALK TYROSINE KINASERECEPTOR) |
3lw0 | INSULIN-LIKE GROWTHFACTOR 1 RECEPTOR (Homosapiens) | 7 / 10 | LEU A1005VAL A1013ALA A1031LYS A1033MET A1082GLY A1085GLY A1152 | NoneNoneNoneCCX A 1 ( 3.7A)NoneNoneCCX A 1 (-3.6A) | 0.95A | 5aacA-3lw0A:29.9 | 5aacA-3lw0A:41.35 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5AAC_A_VGHA9000_1 (ALK TYROSINE KINASERECEPTOR) |
3lw0 | INSULIN-LIKE GROWTHFACTOR 1 RECEPTOR (Homosapiens) | 7 / 10 | VAL A1013ALA A1031LYS A1033MET A1082GLY A1085GLY A1152ASP A1153 | NoneNoneCCX A 1 ( 3.7A)NoneNoneCCX A 1 (-3.6A)CCX A 1 ( 4.3A) | 1.12A | 5aacA-3lw0A:29.9 | 5aacA-3lw0A:41.35 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5H2U_A_1N1A501_1 (PROTEIN-TYROSINEKINASE 6) |
3lw0 | INSULIN-LIKE GROWTHFACTOR 1 RECEPTOR (Homosapiens) | 6 / 12 | LEU A1005VAL A1013ALA A1031LEU A1081GLY A1085GLY A1152 | NoneNoneNoneNoneNoneCCX A 1 (-3.6A) | 0.78A | 5h2uA-3lw0A:27.9 | 5h2uA-3lw0A:37.05 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5H2U_B_1N1B501_1 (PROTEIN-TYROSINEKINASE 6) |
3lw0 | INSULIN-LIKE GROWTHFACTOR 1 RECEPTOR (Homosapiens) | 6 / 12 | LEU A1005VAL A1013ALA A1031LEU A1081GLY A1085GLY A1152 | NoneNoneNoneNoneNoneCCX A 1 (-3.6A) | 0.79A | 5h2uB-3lw0A:28.2 | 5h2uB-3lw0A:37.05 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5LW1_E_ADNE401_1 (MITOGEN-ACTIVATEDPROTEIN KINASE 8) |
3lw0 | INSULIN-LIKE GROWTHFACTOR 1 RECEPTOR (Homosapiens) | 6 / 10 | GLY A1006VAL A1013ALA A1031MET A1079LEU A1081MET A1082 | NoneNoneNoneCCX A 1 ( 3.9A)NoneNone | 0.73A | 5lw1E-3lw0A:21.5 | 5lw1E-3lw0A:13.29 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5LW1_H_ADNH401_1 (MITOGEN-ACTIVATEDPROTEIN KINASE 8) |
3lw0 | INSULIN-LIKE GROWTHFACTOR 1 RECEPTOR (Homosapiens) | 6 / 9 | GLY A1006VAL A1013ALA A1031MET A1079LEU A1081MET A1082 | NoneNoneNoneCCX A 1 ( 3.9A)NoneNone | 0.69A | 5lw1H-3lw0A:21.7 | 5lw1H-3lw0A:13.29 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5VC3_A_DB8A601_2 (WEE1-LIKE PROTEINKINASE) |
3lw0 | INSULIN-LIKE GROWTHFACTOR 1 RECEPTOR (Homosapiens) | 4 / 4 | VAL A1013LYS A1033VAL A1063ASN A1140 | NoneCCX A 1 ( 3.7A)CCX A 1 (-4.1A)None | 0.99A | 5vc3A-3lw0A:22.7 | 5vc3A-3lw0A:23.24 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5VCV_A_1N1A404_1 (MEMBRANE-ASSOCIATEDTYROSINE- ANDTHREONINE-SPECIFICCDC2-INHIBITORYKINASE) |
3lw0 | INSULIN-LIKE GROWTHFACTOR 1 RECEPTOR (Homosapiens) | 6 / 12 | LEU A1005ALA A1031LYS A1033VAL A1063GLY A1085GLY A1152 | NoneNoneCCX A 1 ( 3.7A)CCX A 1 (-4.1A)NoneCCX A 1 (-3.6A) | 1.09A | 5vcvA-3lw0A:22.5 | 5vcvA-3lw0A:25.14 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5W5V_A_ANWA701_0 (SERINE/THREONINE-PROTEIN KINASE TBK1) |
3lw0 | INSULIN-LIKE GROWTHFACTOR 1 RECEPTOR (Homosapiens) | 5 / 9 | LEU A1005ALA A1031VAL A1063MET A1079GLY A1085 | NoneNoneCCX A 1 (-4.1A)CCX A 1 ( 3.9A)None | 0.59A | 5w5vA-3lw0A:13.0 | 5w5vA-3lw0A:18.71 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5Y7Z_A_IREA401_0 (CYCLIN-G-ASSOCIATEDKINASE) |
3lw0 | INSULIN-LIKE GROWTHFACTOR 1 RECEPTOR (Homosapiens) | 7 / 12 | ARG A1003LEU A1005VAL A1013ALA A1031LYS A1033LEU A1081GLY A1085 | NoneNoneNoneNoneCCX A 1 ( 3.7A)NoneNone | 0.70A | 5y7zA-3lw0A:22.2 | 5y7zA-3lw0A:14.77 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5Y7Z_A_IREA401_0 (CYCLIN-G-ASSOCIATEDKINASE) |
3lw0 | INSULIN-LIKE GROWTHFACTOR 1 RECEPTOR (Homosapiens) | 7 / 12 | ARG A1003LEU A1005VAL A1013ALA A1031LYS A1033LEU A1081GLY A1085 | NoneNoneNoneNoneCCX A 1 ( 3.7A)NoneNone | 0.70A | 5y7zA-3lw0A:22.2 | 5y7zA-3lw0A:21.60 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6CJK_C_ACTC301_0 (IMMUNOGLOBULIN FABLIGHT CHAIN) |
3lw0 | INSULIN-LIKE GROWTHFACTOR 1 RECEPTOR (Homosapiens) | 4 / 4 | VAL A1063GLY A1152ASP A1153ASP A1086 | CCX A 1 (-4.1A)CCX A 1 (-3.6A)CCX A 1 ( 4.3A)None | 1.24A | 6cjkC-3lw0A:undetectable | 6cjkC-3lw0A:21.60 |