SIMILAR PATTERN OF AMINO ACIDS MAPPED TO 'CCU'


List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2F78_A_BEZA1003_0
(HTH-TYPE
TRANSCRIPTIONAL
REGULATOR BENM)		 3glb HTH-TYPE
TRANSCRIPTIONAL
REGULATOR CATM
(Acinetobacter
sp.
ADP1) 		4 / 7 VAL A  97
SER A  99
ARG A 146
LEU A 147
 CCU  A   3 (-4.2A)
CCU  A   3 (-2.9A)
None
CCU  A   3 (-4.4A)
 0.56A 2f78A-3glbA:
29.7		 2f78A-3glbA:
54.27
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2F78_A_BEZA1003_0
(HTH-TYPE
TRANSCRIPTIONAL
REGULATOR BENM)		 3glb HTH-TYPE
TRANSCRIPTIONAL
REGULATOR CATM
(Acinetobacter
sp.
ADP1) 		4 / 7 VAL A  97
SER A  99
ARG A 146
PHE A 203
 CCU  A   3 (-4.2A)
CCU  A   3 (-2.9A)
None
None
 0.93A 2f78A-3glbA:
29.7		 2f78A-3glbA:
54.27
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2F78_B_BEZB1004_0
(HTH-TYPE
TRANSCRIPTIONAL
REGULATOR BENM)		 3glb HTH-TYPE
TRANSCRIPTIONAL
REGULATOR CATM
(Acinetobacter
sp.
ADP1) 		4 / 7 VAL A  97
SER A  99
ARG A 146
LEU A 147
 CCU  A   3 (-4.2A)
CCU  A   3 (-2.9A)
None
CCU  A   3 (-4.4A)
 0.56A 2f78B-3glbA:
29.8		 2f78B-3glbA:
54.27
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2F78_B_BEZB1004_0
(HTH-TYPE
TRANSCRIPTIONAL
REGULATOR BENM)		 3glb HTH-TYPE
TRANSCRIPTIONAL
REGULATOR CATM
(Acinetobacter
sp.
ADP1) 		4 / 7 VAL A  97
SER A  99
ARG A 146
PHE A 203
 CCU  A   3 (-4.2A)
CCU  A   3 (-2.9A)
None
None
 0.91A 2f78B-3glbA:
29.8		 2f78B-3glbA:
54.27
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2F8D_A_BEZA1001_0
(HTH-TYPE
TRANSCRIPTIONAL
REGULATOR BENM)		 3glb HTH-TYPE
TRANSCRIPTIONAL
REGULATOR CATM
(Acinetobacter
sp.
ADP1) 		4 / 6 VAL A  97
SER A  99
ARG A 146
LEU A 147
 CCU  A   3 (-4.2A)
CCU  A   3 (-2.9A)
None
CCU  A   3 (-4.4A)
 0.57A 2f8dA-3glbA:
20.7		 2f8dA-3glbA:
54.27
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2F8D_A_BEZA1001_0
(HTH-TYPE
TRANSCRIPTIONAL
REGULATOR BENM)		 3glb HTH-TYPE
TRANSCRIPTIONAL
REGULATOR CATM
(Acinetobacter
sp.
ADP1) 		4 / 6 VAL A  97
SER A  99
ARG A 146
PHE A 203
 CCU  A   3 (-4.2A)
CCU  A   3 (-2.9A)
None
None
 0.94A 2f8dA-3glbA:
20.7		 2f8dA-3glbA:
54.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MJ8_A_SPMA202_1
(SPERMIDINE
N1-ACETYLTRANSFERASE)		 3glb HTH-TYPE
TRANSCRIPTIONAL
REGULATOR CATM
(Acinetobacter
sp.
ADP1) 		4 / 8 ILE A 227
GLU A 226
ILE A 242
LEU A 194
 CCU  A   3 ( 3.7A)
None
None
None
 0.85A 4mj8A-3glbA:
undetectable		 4mj8A-3glbA:
23.27