SIMILAR PATTERN OF AMINO ACIDS MAPPED TO 'CCB'


List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1EE2_A_CHDA1150_0
(ALCOHOL
DEHYDROGENASE)		 1u3t ALCOHOL
DEHYDROGENASE ALPHA
CHAIN
(Homo
sapiens) 		6 / 11 CYH A  46
HIS A  67
LEU A 141
CYH A 174
VAL A 294
ILE A 318
 ZN  A 376 (-2.2A)
ZN  A 376 ( 3.3A)
CCB  A1378 ( 4.8A)
ZN  A 376 (-2.2A)
NAD  A1377 ( 3.9A)
CCB  A1378 ( 4.0A)
 0.31A 1ee2A-1u3tA:
65.3		 1ee2A-1u3tA:
87.17
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1EE2_B_CHDB1250_1
(ALCOHOL
DEHYDROGENASE)		 1u3t ALCOHOL
DEHYDROGENASE ALPHA
CHAIN
(Homo
sapiens) 		6 / 11 CYH A  46
HIS A  67
LEU A 141
CYH A 174
VAL A 294
ILE A 318
 ZN  A 376 (-2.2A)
ZN  A 376 ( 3.3A)
CCB  A1378 ( 4.8A)
ZN  A 376 (-2.2A)
NAD  A1377 ( 3.9A)
CCB  A1378 ( 4.0A)
 0.29A 1ee2B-1u3tA:
65.2		 1ee2B-1u3tA:
87.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2O4L_A_TPVA403_2
(PROTEASE)		 1u3t ALCOHOL
DEHYDROGENASE ALPHA
CHAIN
(Homo
sapiens) 		6 / 12 LEU A 141
GLY A 173
VAL A 152
ILE A  38
VAL A  43
ILE A 143
 CCB  A1378 ( 4.8A)
None
None
None
None
None
 1.25A 2o4lB-1u3tA:
undetectable		 2o4lB-1u3tA:
14.71