SIMILAR PATTERN OF AMINO ACIDS MAPPED TO 'CBS'


List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MXF_A_MTXA1278_1
(PTERIDINE REDUCTASE
2)		 5yqw PEPTIDE ABC
TRANSPORTER,
PERIPLASMIC
PEPTIDE-BINDING
PROTEIN
(Vibrio
harveyi) 		5 / 10 ARG A 436
SER A 359
TYR A 407
ASP A 365
LEU A 484
 CBS  A 604 (-3.1A)
None
None
CBS  A 604 (-2.9A)
None
 1.49A 1mxfA-5yqwA:
undetectable		 1mxfA-5yqwA:
14.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MXF_B_MTXB2278_1
(PTERIDINE REDUCTASE
2)		 5yqw PEPTIDE ABC
TRANSPORTER,
PERIPLASMIC
PEPTIDE-BINDING
PROTEIN
(Vibrio
harveyi) 		5 / 11 ARG A 436
SER A 359
TYR A 407
ASP A 365
LEU A 484
 CBS  A 604 (-3.1A)
None
None
CBS  A 604 (-2.9A)
None
 1.47A 1mxfB-5yqwA:
undetectable		 1mxfB-5yqwA:
14.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MXF_C_MTXC3278_1
(PTERIDINE REDUCTASE
2)		 5yqw PEPTIDE ABC
TRANSPORTER,
PERIPLASMIC
PEPTIDE-BINDING
PROTEIN
(Vibrio
harveyi) 		5 / 11 ARG A 436
SER A 359
TYR A 407
ASP A 365
LEU A 484
 CBS  A 604 (-3.1A)
None
None
CBS  A 604 (-2.9A)
None
 1.47A 1mxfC-5yqwA:
undetectable		 1mxfC-5yqwA:
14.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MXF_D_MTXD4278_1
(PTERIDINE REDUCTASE
2)		 5yqw PEPTIDE ABC
TRANSPORTER,
PERIPLASMIC
PEPTIDE-BINDING
PROTEIN
(Vibrio
harveyi) 		5 / 11 ARG A 436
SER A 359
TYR A 407
ASP A 365
LEU A 484
 CBS  A 604 (-3.1A)
None
None
CBS  A 604 (-2.9A)
None
 1.49A 1mxfD-5yqwA:
undetectable		 1mxfD-5yqwA:
14.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NOD_B_H4BB902_1
(NITRIC OXIDE
SYNTHASE)		 5yqw PEPTIDE ABC
TRANSPORTER,
PERIPLASMIC
PEPTIDE-BINDING
PROTEIN
(Vibrio
harveyi) 		3 / 3 ARG A 509
ILE A 512
TRP A 513
 None
None
CBS  A 604 (-3.8A)
 1.10A 1nodB-5yqwA:
undetectable		 1nodB-5yqwA:
12.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QOM_A_H4BA902_1
(NITRIC OXIDE
SYNTHASE)		 5yqw PEPTIDE ABC
TRANSPORTER,
PERIPLASMIC
PEPTIDE-BINDING
PROTEIN
(Vibrio
harveyi) 		3 / 3 ARG A 509
ILE A 512
TRP A 513
 None
None
CBS  A 604 (-3.8A)
 1.15A 1qomA-5yqwA:
undetectable		 1qomA-5yqwA:
11.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TKQ_B_DVAB8_0
(GRAMICIDIN A)		 3qnq PTS SYSTEM,
CELLOBIOSE-SPECIFIC
IIC COMPONENT
(Bacillus
cereus) 		4 / 5 VAL A 258
GLY A 257
VAL A 255
TRP A 382
 None
None
None
CBS  A 500 (-3.3A)
 1.37A 1tkqB-3qnqA:
undetectable		 1tkqB-3qnqA:
5.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NOD_B_H4BB902_1
(NITRIC OXIDE
SYNTHASE)		 5yqw PEPTIDE ABC
TRANSPORTER,
PERIPLASMIC
PEPTIDE-BINDING
PROTEIN
(Vibrio
harveyi) 		3 / 3 ARG A 509
ILE A 512
TRP A 513
 None
None
CBS  A 604 (-3.8A)
 1.05A 2nodB-5yqwA:
undetectable		 2nodB-5yqwA:
12.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3C0Z_A_SHHA301_1
(HISTONE DEACETYLASE
7A)		 1c7t BETA-N-ACETYLHEXOSAM
INIDASE
(Serratia
marcescens) 		4 / 5 HIS A 375
ASP A 448
HIS A 452
ASP A 539
 None
None
CBS  A1001 (-4.2A)
CBS  A1001 (-3.9A)
 1.21A 3c0zA-1c7tA:
undetectable		 3c0zA-1c7tA:
19.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KU9_B_SPMB700_1
(POLYAMINE OXIDASE)		 1c7t BETA-N-ACETYLHEXOSAM
INIDASE
(Serratia
marcescens) 		4 / 7 GLU A 739
TYR A 669
PHE A 672
TYR A 683
 CBS  A1001 (-2.7A)
CBS  A1001 (-4.4A)
CBS  A1001 (-4.7A)
CBS  A1001 (-4.1A)
 1.32A 3ku9B-1c7tA:
undetectable		 3ku9B-1c7tA:
20.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3L2V_A_RLTA397_1
(INTEGRASE)		 1c7t BETA-N-ACETYLHEXOSAM
INIDASE
(Serratia
marcescens) 		4 / 7 ASP A 448
ASP A 539
GLN A 614
GLU A 446
 None
CBS  A1001 (-3.9A)
None
None
 1.16A 3l2vA-1c7tA:
undetectable		 3l2vA-1c7tA:
18.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LMY_A_CP6A562_1
(BETA-HEXOSAMINIDASE
SUBUNIT BETA)		 1c7t BETA-N-ACETYLHEXOSAM
INIDASE
(Serratia
marcescens) 		8 / 12 ARG A 349
ASP A 378
HIS A 452
ASP A 540
TYR A 669
ASP A 671
TRP A 737
GLU A 739
 CBS  A1001 (-3.0A)
CBS  A1001 ( 4.8A)
CBS  A1001 (-4.2A)
CBS  A1001 ( 4.3A)
CBS  A1001 (-4.4A)
CBS  A1001 (-3.1A)
CBS  A1001 (-3.8A)
CBS  A1001 (-2.7A)
 1.22A 3lmyA-1c7tA:
36.1		 3lmyA-1c7tA:
21.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LMY_A_CP6A562_1
(BETA-HEXOSAMINIDASE
SUBUNIT BETA)		 1c7t BETA-N-ACETYLHEXOSAM
INIDASE
(Serratia
marcescens) 		11 / 12 ARG A 349
HIS A 375
ASP A 378
ASP A 448
HIS A 452
ASP A 539
TRP A 639
TYR A 669
ASP A 671
TRP A 737
GLU A 739
 CBS  A1001 (-3.0A)
None
CBS  A1001 ( 4.8A)
None
CBS  A1001 (-4.2A)
CBS  A1001 (-3.9A)
CBS  A1001 (-3.5A)
CBS  A1001 (-4.4A)
CBS  A1001 (-3.1A)
CBS  A1001 (-3.8A)
CBS  A1001 (-2.7A)
 0.44A 3lmyA-1c7tA:
36.1		 3lmyA-1c7tA:
21.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LMY_B_CP6B563_1
(BETA-HEXOSAMINIDASE
SUBUNIT BETA)		 1c7t BETA-N-ACETYLHEXOSAM
INIDASE
(Serratia
marcescens) 		7 / 12 ARG A 349
ASP A 378
HIS A 452
ASP A 540
TYR A 669
TRP A 737
GLU A 739
 CBS  A1001 (-3.0A)
CBS  A1001 ( 4.8A)
CBS  A1001 (-4.2A)
CBS  A1001 ( 4.3A)
CBS  A1001 (-4.4A)
CBS  A1001 (-3.8A)
CBS  A1001 (-2.7A)
 1.28A 3lmyB-1c7tA:
36.1		 3lmyB-1c7tA:
21.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LMY_B_CP6B563_1
(BETA-HEXOSAMINIDASE
SUBUNIT BETA)		 1c7t BETA-N-ACETYLHEXOSAM
INIDASE
(Serratia
marcescens) 		11 / 12 ARG A 349
HIS A 375
ASP A 378
ASP A 448
HIS A 452
ASP A 539
TRP A 616
TRP A 639
TYR A 669
TRP A 737
GLU A 739
 CBS  A1001 (-3.0A)
None
CBS  A1001 ( 4.8A)
None
CBS  A1001 (-4.2A)
CBS  A1001 (-3.9A)
CBS  A1001 (-3.6A)
CBS  A1001 (-3.5A)
CBS  A1001 (-4.4A)
CBS  A1001 (-3.8A)
CBS  A1001 (-2.7A)
 0.44A 3lmyB-1c7tA:
36.1		 3lmyB-1c7tA:
21.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LMY_B_CP6B563_1
(BETA-HEXOSAMINIDASE
SUBUNIT BETA)		 1c7t BETA-N-ACETYLHEXOSAM
INIDASE
(Serratia
marcescens) 		5 / 12 HIS A 375
ASP A 378
GLU A 739
TYR A 669
TRP A 737
 None
CBS  A1001 ( 4.8A)
CBS  A1001 (-2.7A)
CBS  A1001 (-4.4A)
CBS  A1001 (-3.8A)
 1.34A 3lmyB-1c7tA:
36.1		 3lmyB-1c7tA:
21.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NVC_A_SALA370_1
(GENTISATE
1,2-DIOXYGENASE)		 1c7t BETA-N-ACETYLHEXOSAM
INIDASE
(Serratia
marcescens) 		4 / 6 GLN A 494
ARG A 349
HIS A 375
ASP A 379
 CBS  A1001 ( 4.2A)
CBS  A1001 (-3.0A)
None
None
 0.92A 3nvcA-1c7tA:
undetectable		 3nvcA-1c7tA:
19.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NW2_A_H4BA902_1
(NITRIC OXIDE
SYNTHASE, INDUCIBLE)		 5yqw PEPTIDE ABC
TRANSPORTER,
PERIPLASMIC
PEPTIDE-BINDING
PROTEIN
(Vibrio
harveyi) 		3 / 3 ARG A 509
ILE A 512
TRP A 513
 None
None
CBS  A 604 (-3.8A)
 1.09A 3nw2A-5yqwA:
undetectable		 3nw2A-5yqwA:
12.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NW2_B_H4BB902_1
(NITRIC OXIDE
SYNTHASE, INDUCIBLE)		 5yqw PEPTIDE ABC
TRANSPORTER,
PERIPLASMIC
PEPTIDE-BINDING
PROTEIN
(Vibrio
harveyi) 		3 / 3 ARG A 509
ILE A 512
TRP A 513
 None
None
CBS  A 604 (-3.8A)
 1.09A 3nw2B-5yqwA:
undetectable		 3nw2B-5yqwA:
12.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S3O_A_DLUA399_1
(PFV INTEGRASE)		 1c7t BETA-N-ACETYLHEXOSAM
INIDASE
(Serratia
marcescens) 		4 / 7 ASP A 448
ASP A 539
GLN A 614
GLU A 446
 None
CBS  A1001 (-3.9A)
None
None
 1.15A 3s3oA-1c7tA:
undetectable		 3s3oA-1c7tA:
18.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WQW_A_GCSA502_1
(CHITINASE)		 5yqw PEPTIDE ABC
TRANSPORTER,
PERIPLASMIC
PEPTIDE-BINDING
PROTEIN
(Vibrio
harveyi) 		4 / 5 GLY A 515
TRP A 513
ALA A 514
PHE A 391
 None
CBS  A 604 (-3.8A)
None
None
 1.13A 3wqwA-5yqwA:
undetectable		 3wqwA-5yqwA:
13.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A97_A_ZPCA1318_1
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 1c7t BETA-N-ACETYLHEXOSAM
INIDASE
(Serratia
marcescens) 		4 / 7 GLU A 380
GLU A 739
HIS A 373
VAL A 357
 None
CBS  A1001 (-2.7A)
None
None
 1.01A 4a97A-1c7tA:
3.1		 4a97A-1c7tA:
16.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QA0_B_SHHB404_2
(HISTONE DEACETYLASE
8)		 1c7t BETA-N-ACETYLHEXOSAM
INIDASE
(Serratia
marcescens) 		5 / 11 TYR A 683
HIS A 373
HIS A 375
ASP A 448
GLY A 537
 CBS  A1001 (-4.1A)
None
None
None
None
 1.46A 4qa0B-1c7tA:
undetectable		 4qa0B-1c7tA:
16.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BS8_G_MFXG101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B
DNA SUBSTRATE 24-MER
TTACGTGCATAGTCATTCAT
GACC)		 1c7t BETA-N-ACETYLHEXOSAM
INIDASE
(Serratia
marcescens) 		4 / 7 ASP A 346
ARG A 349
GLY A 381
GLU A 380
 None
CBS  A1001 (-3.0A)
None
None
 0.80A 5bs8A-1c7tA:
0.0
5bs8C-1c7tA:
0.0
5bs8D-1c7tA:
undetectable		 5bs8A-1c7tA:
21.29
5bs8C-1c7tA:
21.29
5bs8D-1c7tA:
15.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BS8_H_MFXH101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B
DNA SUBSTRATE 24-MER
GGTCATGAATGACTATGCAC
GTAA)		 1c7t BETA-N-ACETYLHEXOSAM
INIDASE
(Serratia
marcescens) 		4 / 7 ASP A 346
ARG A 349
GLY A 381
GLU A 380
 None
CBS  A1001 (-3.0A)
None
None
 0.81A 5bs8A-1c7tA:
undetectable
5bs8B-1c7tA:
undetectable
5bs8C-1c7tA:
0.0		 5bs8A-1c7tA:
21.29
5bs8B-1c7tA:
15.47
5bs8C-1c7tA:
21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BTA_G_MFXG101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B
DNA SUBSTRATE 24-MER
TTACGTGCATAGTCATTCAT
GACC)		 1c7t BETA-N-ACETYLHEXOSAM
INIDASE
(Serratia
marcescens) 		4 / 7 ASP A 346
ARG A 349
GLY A 381
GLU A 380
 None
CBS  A1001 (-3.0A)
None
None
 0.83A 5btaA-1c7tA:
0.0
5btaC-1c7tA:
0.0
5btaD-1c7tA:
undetectable		 5btaA-1c7tA:
21.46
5btaC-1c7tA:
21.46
5btaD-1c7tA:
15.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BTD_E_GFNE101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B
DNA SUBSTRATE 24-MER
GGTCATGAATGACTATGCAC
GTAA)		 1c7t BETA-N-ACETYLHEXOSAM
INIDASE
(Serratia
marcescens) 		4 / 7 ASP A 346
ARG A 349
GLY A 381
GLU A 380
 None
CBS  A1001 (-3.0A)
None
None
 0.81A 5btdA-1c7tA:
0.0
5btdB-1c7tA:
0.0
5btdC-1c7tA:
0.0		 5btdA-1c7tA:
21.29
5btdB-1c7tA:
15.47
5btdC-1c7tA:
21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BTD_G_GFNG101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B
DNA SUBSTRATE 24-MER
TTACGTGCATAGTCATTCAT
GACC)		 1c7t BETA-N-ACETYLHEXOSAM
INIDASE
(Serratia
marcescens) 		4 / 7 ASP A 346
ARG A 349
GLY A 381
GLU A 380
 None
CBS  A1001 (-3.0A)
None
None
 0.79A 5btdA-1c7tA:
0.0
5btdC-1c7tA:
0.0
5btdD-1c7tA:
undetectable		 5btdA-1c7tA:
21.29
5btdC-1c7tA:
21.29
5btdD-1c7tA:
15.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BTF_F_GFNF101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B
DNA SUBSTRATE 24-MER
TTACGTGCATAGTCATTCAT
GACC)		 1c7t BETA-N-ACETYLHEXOSAM
INIDASE
(Serratia
marcescens) 		4 / 7 ASP A 346
ARG A 349
GLY A 381
GLU A 380
 None
CBS  A1001 (-3.0A)
None
None
 0.81A 5btfA-1c7tA:
0.0
5btfB-1c7tA:
undetectable
5btfC-1c7tA:
0.0		 5btfA-1c7tA:
21.46
5btfB-1c7tA:
15.47
5btfC-1c7tA:
21.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BTF_G_GFNG101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B
DNA SUBSTRATE 24-MER
TTACGTGCATAGTCATTCAT
GACC)		 1c7t BETA-N-ACETYLHEXOSAM
INIDASE
(Serratia
marcescens) 		4 / 7 ASP A 346
ARG A 349
GLY A 381
GLU A 380
 None
CBS  A1001 (-3.0A)
None
None
 0.75A 5btfA-1c7tA:
0.0
5btfC-1c7tA:
0.0
5btfD-1c7tA:
undetectable		 5btfA-1c7tA:
21.46
5btfC-1c7tA:
21.46
5btfD-1c7tA:
15.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BTG_F_LFXF101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B
DNA SUBSTRATE 24-MER
TTACGTGCATAGTCATTCAT
GACC)		 1c7t BETA-N-ACETYLHEXOSAM
INIDASE
(Serratia
marcescens) 		4 / 7 ASP A 346
ARG A 349
GLY A 381
GLU A 380
 None
CBS  A1001 (-3.0A)
None
None
 0.90A 5btgA-1c7tA:
undetectable
5btgC-1c7tA:
0.0
5btgD-1c7tA:
undetectable		 5btgA-1c7tA:
21.29
5btgC-1c7tA:
21.29
5btgD-1c7tA:
15.47
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5NCD_A_ACTA301_0
(PEPTIDOGLYCAN
N-ACETYLGLUCOSAMINE
DEACETYLASE)		 5lgc ARCE4A
(Arthrobacter
sp.
AW19M34-1) 		5 / 6 ASP A  32
ASP A  33
HIS A  82
HIS A  86
HIS A 173
 CBS  A 301 (-4.0A)
CBS  A 301 (-2.9A)
CBS  A 301 (-3.8A)
CBS  A 301 (-3.7A)
CBS  A 301 (-4.3A)
 0.41A 5ncdA-5lgcA:
24.7
5ncdD-5lgcA:
25.0		 5ncdA-5lgcA:
33.47
5ncdD-5lgcA:
33.47
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5NCD_C_ACTC301_0
(PEPTIDOGLYCAN
N-ACETYLGLUCOSAMINE
DEACETYLASE)		 5lgc ARCE4A
(Arthrobacter
sp.
AW19M34-1) 		5 / 6 ASP A  32
ASP A  33
HIS A  82
HIS A  86
HIS A 173
 CBS  A 301 (-4.0A)
CBS  A 301 (-2.9A)
CBS  A 301 (-3.8A)
CBS  A 301 (-3.7A)
CBS  A 301 (-4.3A)
 0.33A 5ncdB-5lgcA:
25.0
5ncdC-5lgcA:
25.0		 5ncdB-5lgcA:
33.47
5ncdC-5lgcA:
33.47
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5NCD_D_ACTD301_0
(PEPTIDOGLYCAN
N-ACETYLGLUCOSAMINE
DEACETYLASE)		 5lgc ARCE4A
(Arthrobacter
sp.
AW19M34-1) 		4 / 4 ASP A  32
HIS A  82
HIS A  86
HIS A 173
 CBS  A 301 (-4.0A)
CBS  A 301 (-3.8A)
CBS  A 301 (-3.7A)
CBS  A 301 (-4.3A)
 0.28A 5ncdD-5lgcA:
25.0		 5ncdD-5lgcA:
33.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NEK_B_AZMB302_1
(PEPTIDOGLYCAN
N-ACETYLGLUCOSAMINE
DEACETYLASE)		 5lgc ARCE4A
(Arthrobacter
sp.
AW19M34-1) 		7 / 8 ASP A  32
ASP A  33
HIS A  82
HIS A  86
PRO A 122
TRP A 148
HIS A 173
 CBS  A 301 (-4.0A)
CBS  A 301 (-2.9A)
CBS  A 301 (-3.8A)
CBS  A 301 (-3.7A)
CBS  A 301 ( 4.6A)
CBS  A 301 (-3.7A)
CBS  A 301 (-4.3A)
 0.53A 5nekB-5lgcA:
24.9		 5nekB-5lgcA:
15.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NEK_D_AZMD302_1
(PEPTIDOGLYCAN
N-ACETYLGLUCOSAMINE
DEACETYLASE)		 5lgc ARCE4A
(Arthrobacter
sp.
AW19M34-1) 		7 / 8 ASP A  32
ASP A  33
HIS A  82
HIS A  86
TRP A 141
TRP A 148
HIS A 173
 CBS  A 301 (-4.0A)
CBS  A 301 (-2.9A)
CBS  A 301 (-3.8A)
CBS  A 301 (-3.7A)
CBS  A 301 (-4.6A)
CBS  A 301 (-3.7A)
CBS  A 301 (-4.3A)
 0.58A 5nekD-5lgcA:
24.8		 5nekD-5lgcA:
15.56
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5NEL_A_ACTA302_0
(PEPTIDOGLYCAN
N-ACETYLGLUCOSAMINE
DEACETYLASE)		 5lgc ARCE4A
(Arthrobacter
sp.
AW19M34-1) 		5 / 6 ASP A  32
ASP A  33
HIS A  82
HIS A  86
HIS A 173
 CBS  A 301 (-4.0A)
CBS  A 301 (-2.9A)
CBS  A 301 (-3.8A)
CBS  A 301 (-3.7A)
CBS  A 301 (-4.3A)
 0.49A 5nelA-5lgcA:
24.6
5nelD-5lgcA:
24.9		 5nelA-5lgcA:
33.47
5nelD-5lgcA:
33.47
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5NEL_C_ACTC302_0
(PEPTIDOGLYCAN
N-ACETYLGLUCOSAMINE
DEACETYLASE)		 5lgc ARCE4A
(Arthrobacter
sp.
AW19M34-1) 		5 / 6 ASP A  32
HIS A  82
HIS A  86
LEU A 171
HIS A 173
 CBS  A 301 (-4.0A)
CBS  A 301 (-3.8A)
CBS  A 301 (-3.7A)
None
CBS  A 301 (-4.3A)
 0.36A 5nelB-5lgcA:
25.0
5nelC-5lgcA:
24.7		 5nelB-5lgcA:
33.47
5nelC-5lgcA:
33.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OEX_B_CUB601_0
(THIOCYANATE
DEHYDROGENASE)		 5lgc ARCE4A
(Arthrobacter
sp.
AW19M34-1) 		3 / 3 HIS A 173
ASP A  33
HIS A  82
 CBS  A 301 (-4.3A)
CBS  A 301 (-2.9A)
CBS  A 301 (-3.8A)
 0.73A 5oexB-5lgcA:
undetectable		 5oexB-5lgcA:
19.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OEX_C_CUC601_0
(THIOCYANATE
DEHYDROGENASE)		 5lgc ARCE4A
(Arthrobacter
sp.
AW19M34-1) 		3 / 3 HIS A 173
ASP A  33
HIS A  82
 CBS  A 301 (-4.3A)
CBS  A 301 (-2.9A)
CBS  A 301 (-3.8A)
 0.73A 5oexC-5lgcA:
undetectable		 5oexC-5lgcA:
19.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OEX_D_CUD601_0
(THIOCYANATE
DEHYDROGENASE)		 5lgc ARCE4A
(Arthrobacter
sp.
AW19M34-1) 		3 / 3 HIS A 173
ASP A  33
HIS A  82
 CBS  A 301 (-4.3A)
CBS  A 301 (-2.9A)
CBS  A 301 (-3.8A)
 0.73A 5oexD-5lgcA:
undetectable		 5oexD-5lgcA:
19.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z6K_A_FOLA201_1
(DIHYDROFOLATE
REDUCTASE)		 5yqw PEPTIDE ABC
TRANSPORTER,
PERIPLASMIC
PEPTIDE-BINDING
PROTEIN
(Vibrio
harveyi) 		3 / 3 MET A 489
ASP A 365
ARG A 436
 CBS  A 604 (-4.1A)
CBS  A 604 (-2.9A)
CBS  A 604 (-3.1A)
 1.19A 5z6kA-5yqwA:
undetectable		 5z6kA-5yqwA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MN8_A_GLYA607_0
(UNCHARACTERIZED
PROTEIN)		 1c7t BETA-N-ACETYLHEXOSAM
INIDASE
(Serratia
marcescens) 		4 / 4 GLU A 446
ASP A 346
ARG A 349
TRP A 737
 None
None
CBS  A1001 (-3.0A)
CBS  A1001 (-3.8A)
 1.01A 6mn8A-1c7tA:
0.2		 6mn8A-1c7tA:
19.19