SIMILAR PATTERN OF AMINO ACIDS MAPPED TO 'CBK'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1ZLQ_A_ACTA1507_0 (NICKEL-BINDING PERIPLASMIC PROTEIN)	4doe	1,4-BETA-GLUCANASE (Caldicellulosiru ptor bescii)	3 / 3	GLN A 42 HIS A 397 ARG A 398	None None CBK A 503 (-2.5A)	0.85A	1zlqA-4doeA: undetectable	1zlqA-4doeA: 21.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4XI3_B_29SB601_2 (ESTROGEN RECEPTOR)	4jjj	CELLULOSE 1,4-BETA-CELLOBIOSID ASE (Thermobifida fusca)	4 / 5	GLU A 40 MET A 37 LEU A 596 HIS A 603	CBK A 702 ( 3.4A) None None ZN A 716 (-3.2A)	1.30A	4xi3B-4jjjA: undetectable	4xi3B-4jjjA: 17.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5B8I_C_FK5C201_1 (SERINE/THREONINE-PRO TEIN PHOSPHATASE PEPTIDYL-PROLYL CIS-TRANS ISOMERASE)	4jjj	CELLULOSE 1,4-BETA-CELLOBIOSID ASE (Thermobifida fusca)	4 / 6	LEU A 604 SER A 548 PRO A 547 GLU A 40	None ZN A 735 (-3.9A) None CBK A 702 ( 3.4A)	1.17A	5b8iA-4jjjA: undetectable	5b8iA-4jjjA: 19.82