SIMILAR PATTERN OF AMINO ACIDS MAPPED TO 'CBH'


List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NW3_A_SAMA500_0
(HISTONE
METHYLTRANSFERASE
DOT1L)		 1lt8 BETAINE-HOMOCYSTEINE
METHYLTRANSFERASE
(Homo
sapiens) 		5 / 12 GLU A  34
GLY A  28
ALA A 250
PHE A  74
PHE A  63
 None
CBH  A 601 (-3.5A)
None
None
None
 1.32A 1nw3A-1lt8A:
undetectable		 1nw3A-1lt8A:
22.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UT5_D_LOCD502_1
(TUBULIN BETA CHAIN)		 1lt8 BETAINE-HOMOCYSTEINE
METHYLTRANSFERASE
(Homo
sapiens) 		5 / 12 GLN A  72
ASN A 216
ALA A 182
ALA A 119
ILE A 212
 CBH  A 601 ( 4.1A)
None
None
None
None
 1.07A 3ut5D-1lt8A:
3.2		 3ut5D-1lt8A:
18.49