SIMILAR PATTERN OF AMINO ACIDS MAPPED TO 'CAU'


List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2Y00_A_Y00A601_1
(BETA-1 ADRENERGIC
RECEPTOR)		 4gbr BETA-2 ADRENERGIC
RECEPTOR
(Homo
sapiens) 		8 / 12 TRP A 109
ASP A 113
VAL A 114
PHE A 261
PHE A 262
ASN A 265
ASN A 284
TYR A 288
 None
CAU  A 500 (-3.0A)
CAU  A 500 (-3.5A)
CAU  A 500 (-4.2A)
CAU  A 500 (-4.6A)
CAU  A 500 (-3.4A)
CAU  A 500 (-3.3A)
CAU  A 500 (-4.6A)
 0.64A 2y00A-4gbrA:
39.3		 2y00A-4gbrA:
58.02
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2Y00_A_Y00A601_1
(BETA-1 ADRENERGIC
RECEPTOR)		 4gbr BETA-2 ADRENERGIC
RECEPTOR
(Homo
sapiens) 		7 / 12 TRP A 109
ASP A 113
VAL A 114
SER A 203
PHE A 261
PHE A 262
ASN A 284
 None
CAU  A 500 (-3.0A)
CAU  A 500 (-3.5A)
CAU  A 500 (-3.3A)
CAU  A 500 (-4.2A)
CAU  A 500 (-4.6A)
CAU  A 500 (-3.3A)
 1.40A 2y00A-4gbrA:
39.3		 2y00A-4gbrA:
58.02
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2Y00_A_Y00A601_1
(BETA-1 ADRENERGIC
RECEPTOR)		 4gbr BETA-2 ADRENERGIC
RECEPTOR
(Homo
sapiens) 		8 / 12 TRP A 109
ASP A 113
VAL A 114
SER A 203
PHE A 261
PHE A 262
ASN A 284
TYR A 288
 None
CAU  A 500 (-3.0A)
CAU  A 500 (-3.5A)
CAU  A 500 (-3.3A)
CAU  A 500 (-4.2A)
CAU  A 500 (-4.6A)
CAU  A 500 (-3.3A)
CAU  A 500 (-4.6A)
 0.74A 2y00A-4gbrA:
39.3		 2y00A-4gbrA:
58.02
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2Y00_A_Y00A601_1
(BETA-1 ADRENERGIC
RECEPTOR)		 4gbr BETA-2 ADRENERGIC
RECEPTOR
(Homo
sapiens) 		8 / 12 TRP A 109
ASP A 113
VAL A 114
SER A 203
SER A 207
PHE A 261
PHE A 262
TYR A 288
 None
CAU  A 500 (-3.0A)
CAU  A 500 (-3.5A)
CAU  A 500 (-3.3A)
CAU  A 500 (-4.1A)
CAU  A 500 (-4.2A)
CAU  A 500 (-4.6A)
CAU  A 500 (-4.6A)
 0.76A 2y00A-4gbrA:
39.3		 2y00A-4gbrA:
58.02
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2Y00_A_Y00A601_1
(BETA-1 ADRENERGIC
RECEPTOR)		 4gbr BETA-2 ADRENERGIC
RECEPTOR
(Homo
sapiens) 		8 / 12 TRP A 109
ASP A 113
VAL A 114
SER A 207
PHE A 261
PHE A 262
ASN A 265
TYR A 288
 None
CAU  A 500 (-3.0A)
CAU  A 500 (-3.5A)
CAU  A 500 (-4.1A)
CAU  A 500 (-4.2A)
CAU  A 500 (-4.6A)
CAU  A 500 (-3.4A)
CAU  A 500 (-4.6A)
 0.66A 2y00A-4gbrA:
39.3		 2y00A-4gbrA:
58.02
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2Y00_A_Y00A601_1
(BETA-1 ADRENERGIC
RECEPTOR)		 4gbr BETA-2 ADRENERGIC
RECEPTOR
(Homo
sapiens) 		6 / 12 TRP A 109
ASP A 113
VAL A 114
SER A 207
PHE A 262
TYR A 288
 None
CAU  A 500 (-3.0A)
CAU  A 500 (-3.5A)
CAU  A 500 (-4.1A)
CAU  A 500 (-4.6A)
CAU  A 500 (-4.6A)
 1.49A 2y00A-4gbrA:
39.3		 2y00A-4gbrA:
58.02
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2Y00_B_Y00B601_1
(BETA-1 ADRENERGIC
RECEPTOR)		 4gbr BETA-2 ADRENERGIC
RECEPTOR
(Homo
sapiens) 		6 / 12 TRP A 109
ASP A 113
VAL A 114
SER A 207
PHE A 262
TYR A 288
 None
CAU  A 500 (-3.0A)
CAU  A 500 (-3.5A)
CAU  A 500 (-4.1A)
CAU  A 500 (-4.6A)
CAU  A 500 (-4.6A)
 1.48A 2y00B-4gbrA:
39.0		 2y00B-4gbrA:
58.02
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2Y00_B_Y00B601_1
(BETA-1 ADRENERGIC
RECEPTOR)		 4gbr BETA-2 ADRENERGIC
RECEPTOR
(Homo
sapiens) 		7 / 12 TRP A 109
THR A 110
ASP A 113
VAL A 114
SER A 203
PHE A 261
PHE A 262
 None
CAU  A 500 ( 4.0A)
CAU  A 500 (-3.0A)
CAU  A 500 (-3.5A)
CAU  A 500 (-3.3A)
CAU  A 500 (-4.2A)
CAU  A 500 (-4.6A)
 1.32A 2y00B-4gbrA:
39.0		 2y00B-4gbrA:
58.02
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2Y00_B_Y00B601_1
(BETA-1 ADRENERGIC
RECEPTOR)		 4gbr BETA-2 ADRENERGIC
RECEPTOR
(Homo
sapiens) 		9 / 12 TRP A 109
THR A 110
ASP A 113
VAL A 114
SER A 203
SER A 207
PHE A 261
PHE A 262
TYR A 288
 None
CAU  A 500 ( 4.0A)
CAU  A 500 (-3.0A)
CAU  A 500 (-3.5A)
CAU  A 500 (-3.3A)
CAU  A 500 (-4.1A)
CAU  A 500 (-4.2A)
CAU  A 500 (-4.6A)
CAU  A 500 (-4.6A)
 0.70A 2y00B-4gbrA:
39.0		 2y00B-4gbrA:
58.02
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2Y00_B_Y00B601_1
(BETA-1 ADRENERGIC
RECEPTOR)		 4gbr BETA-2 ADRENERGIC
RECEPTOR
(Homo
sapiens) 		9 / 12 TRP A 109
THR A 110
ASP A 113
VAL A 114
SER A 207
PHE A 261
PHE A 262
ASN A 265
TYR A 288
 None
CAU  A 500 ( 4.0A)
CAU  A 500 (-3.0A)
CAU  A 500 (-3.5A)
CAU  A 500 (-4.1A)
CAU  A 500 (-4.2A)
CAU  A 500 (-4.6A)
CAU  A 500 (-3.4A)
CAU  A 500 (-4.6A)
 0.63A 2y00B-4gbrA:
39.0		 2y00B-4gbrA:
58.02
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2Y00_B_Y00B601_2
(BETA-1 ADRENERGIC
RECEPTOR)		 4gbr BETA-2 ADRENERGIC
RECEPTOR
(Homo
sapiens) 		3 / 3 VAL A 117
ASN A 284
TRP A 285
 CAU  A 500 (-4.2A)
CAU  A 500 (-3.3A)
None
 0.65A 2y00B-4gbrA:
39.0		 2y00B-4gbrA:
58.02
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2Y01_A_Y00A601_1
(BETA-1 ADRENERGIC
RECEPTOR)		 4gbr BETA-2 ADRENERGIC
RECEPTOR
(Homo
sapiens) 		9 / 12 TRP A 109
ASP A 113
PHE A 193
PHE A 261
PHE A 262
ASN A 265
ASN A 284
TRP A 285
TYR A 288
 None
CAU  A 500 (-3.0A)
CAU  A 500 (-4.5A)
CAU  A 500 (-4.2A)
CAU  A 500 (-4.6A)
CAU  A 500 (-3.4A)
CAU  A 500 (-3.3A)
None
CAU  A 500 (-4.6A)
 0.72A 2y01A-4gbrA:
38.8		 2y01A-4gbrA:
58.02
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2Y01_A_Y00A601_1
(BETA-1 ADRENERGIC
RECEPTOR)		 4gbr BETA-2 ADRENERGIC
RECEPTOR
(Homo
sapiens) 		9 / 12 TRP A 109
ASP A 113
PHE A 193
SER A 203
PHE A 261
PHE A 262
ASN A 284
TRP A 285
TYR A 288
 None
CAU  A 500 (-3.0A)
CAU  A 500 (-4.5A)
CAU  A 500 (-3.3A)
CAU  A 500 (-4.2A)
CAU  A 500 (-4.6A)
CAU  A 500 (-3.3A)
None
CAU  A 500 (-4.6A)
 0.84A 2y01A-4gbrA:
38.8		 2y01A-4gbrA:
58.02
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2Y01_A_Y00A601_1
(BETA-1 ADRENERGIC
RECEPTOR)		 4gbr BETA-2 ADRENERGIC
RECEPTOR
(Homo
sapiens) 		5 / 12 TRP A 109
ASP A 113
SER A 207
PHE A 262
TYR A 288
 None
CAU  A 500 (-3.0A)
CAU  A 500 (-4.1A)
CAU  A 500 (-4.6A)
CAU  A 500 (-4.6A)
 1.19A 2y01A-4gbrA:
38.8		 2y01A-4gbrA:
58.02
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2Y01_B_Y00B601_1
(BETA-1 ADRENERGIC
RECEPTOR)		 4gbr BETA-2 ADRENERGIC
RECEPTOR
(Homo
sapiens) 		6 / 12 TRP A 109
ASP A 113
VAL A 114
SER A 207
PHE A 262
TYR A 288
 None
CAU  A 500 (-3.0A)
CAU  A 500 (-3.5A)
CAU  A 500 (-4.1A)
CAU  A 500 (-4.6A)
CAU  A 500 (-4.6A)
 1.48A 2y01B-4gbrA:
38.7		 2y01B-4gbrA:
58.02
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2Y01_B_Y00B601_1
(BETA-1 ADRENERGIC
RECEPTOR)		 4gbr BETA-2 ADRENERGIC
RECEPTOR
(Homo
sapiens) 		7 / 12 TRP A 109
THR A 110
ASP A 113
VAL A 114
SER A 203
PHE A 261
PHE A 262
 None
CAU  A 500 ( 4.0A)
CAU  A 500 (-3.0A)
CAU  A 500 (-3.5A)
CAU  A 500 (-3.3A)
CAU  A 500 (-4.2A)
CAU  A 500 (-4.6A)
 1.28A 2y01B-4gbrA:
38.7		 2y01B-4gbrA:
58.02
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2Y01_B_Y00B601_1
(BETA-1 ADRENERGIC
RECEPTOR)		 4gbr BETA-2 ADRENERGIC
RECEPTOR
(Homo
sapiens) 		9 / 12 TRP A 109
THR A 110
ASP A 113
VAL A 114
SER A 203
SER A 207
PHE A 261
PHE A 262
TYR A 288
 None
CAU  A 500 ( 4.0A)
CAU  A 500 (-3.0A)
CAU  A 500 (-3.5A)
CAU  A 500 (-3.3A)
CAU  A 500 (-4.1A)
CAU  A 500 (-4.2A)
CAU  A 500 (-4.6A)
CAU  A 500 (-4.6A)
 0.69A 2y01B-4gbrA:
38.7		 2y01B-4gbrA:
58.02
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2Y01_B_Y00B601_1
(BETA-1 ADRENERGIC
RECEPTOR)		 4gbr BETA-2 ADRENERGIC
RECEPTOR
(Homo
sapiens) 		9 / 12 TRP A 109
THR A 110
ASP A 113
VAL A 114
SER A 207
PHE A 261
PHE A 262
ASN A 265
TYR A 288
 None
CAU  A 500 ( 4.0A)
CAU  A 500 (-3.0A)
CAU  A 500 (-3.5A)
CAU  A 500 (-4.1A)
CAU  A 500 (-4.2A)
CAU  A 500 (-4.6A)
CAU  A 500 (-3.4A)
CAU  A 500 (-4.6A)
 0.64A 2y01B-4gbrA:
38.7		 2y01B-4gbrA:
58.02
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2Y03_A_5FWA601_1
(BETA-1 ADRENERGIC
RECEPTOR)		 4gbr BETA-2 ADRENERGIC
RECEPTOR
(Homo
sapiens) 		5 / 12 TRP A 109
ASP A 113
VAL A 114
SER A 203
PHE A 261
 None
CAU  A 500 (-3.0A)
CAU  A 500 (-3.5A)
CAU  A 500 (-3.3A)
CAU  A 500 (-4.2A)
 1.39A 2y03A-4gbrA:
39.4		 2y03A-4gbrA:
58.02
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2Y03_A_5FWA601_1
(BETA-1 ADRENERGIC
RECEPTOR)		 4gbr BETA-2 ADRENERGIC
RECEPTOR
(Homo
sapiens) 		6 / 12 TRP A 109
ASP A 113
VAL A 114
SER A 207
PHE A 262
TYR A 288
 None
CAU  A 500 (-3.0A)
CAU  A 500 (-3.5A)
CAU  A 500 (-4.1A)
CAU  A 500 (-4.6A)
CAU  A 500 (-4.6A)
 1.48A 2y03A-4gbrA:
39.4		 2y03A-4gbrA:
58.02
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2Y03_A_5FWA601_1
(BETA-1 ADRENERGIC
RECEPTOR)		 4gbr BETA-2 ADRENERGIC
RECEPTOR
(Homo
sapiens) 		10 / 12 TRP A 109
ASP A 113
VAL A 114
VAL A 117
PHE A 193
PHE A 261
PHE A 262
ASN A 265
ASN A 284
TYR A 288
 None
CAU  A 500 (-3.0A)
CAU  A 500 (-3.5A)
CAU  A 500 (-4.2A)
CAU  A 500 (-4.5A)
CAU  A 500 (-4.2A)
CAU  A 500 (-4.6A)
CAU  A 500 (-3.4A)
CAU  A 500 (-3.3A)
CAU  A 500 (-4.6A)
 0.57A 2y03A-4gbrA:
39.4		 2y03A-4gbrA:
58.02
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2Y03_A_5FWA601_1
(BETA-1 ADRENERGIC
RECEPTOR)		 4gbr BETA-2 ADRENERGIC
RECEPTOR
(Homo
sapiens) 		9 / 12 TRP A 109
ASP A 113
VAL A 114
VAL A 117
PHE A 193
SER A 203
PHE A 261
PHE A 262
TYR A 288
 None
CAU  A 500 (-3.0A)
CAU  A 500 (-3.5A)
CAU  A 500 (-4.2A)
CAU  A 500 (-4.5A)
CAU  A 500 (-3.3A)
CAU  A 500 (-4.2A)
CAU  A 500 (-4.6A)
CAU  A 500 (-4.6A)
 0.65A 2y03A-4gbrA:
39.4		 2y03A-4gbrA:
58.02
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2Y03_A_5FWA601_1
(BETA-1 ADRENERGIC
RECEPTOR)		 4gbr BETA-2 ADRENERGIC
RECEPTOR
(Homo
sapiens) 		5 / 12 TRP A 109
VAL A 114
PHE A 193
SER A 203
SER A 207
 None
CAU  A 500 (-3.5A)
CAU  A 500 (-4.5A)
CAU  A 500 (-3.3A)
CAU  A 500 (-4.1A)
 0.97A 2y03A-4gbrA:
39.4		 2y03A-4gbrA:
58.02
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2Y03_A_5FWA601_1
(BETA-1 ADRENERGIC
RECEPTOR)		 4gbr BETA-2 ADRENERGIC
RECEPTOR
(Homo
sapiens) 		5 / 12 TRP A 109
VAL A 114
PHE A 193
SER A 207
ASN A 265
 None
CAU  A 500 (-3.5A)
CAU  A 500 (-4.5A)
CAU  A 500 (-4.1A)
CAU  A 500 (-3.4A)
 0.90A 2y03A-4gbrA:
39.4		 2y03A-4gbrA:
58.02
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2Y03_A_5FWA601_1
(BETA-1 ADRENERGIC
RECEPTOR)		 4gbr BETA-2 ADRENERGIC
RECEPTOR
(Homo
sapiens) 		5 / 12 VAL A 117
PHE A 261
ASN A 265
ASN A 284
TYR A 288
 CAU  A 500 (-4.2A)
CAU  A 500 (-4.2A)
CAU  A 500 (-3.4A)
CAU  A 500 (-3.3A)
CAU  A 500 (-4.6A)
 1.24A 2y03A-4gbrA:
39.4		 2y03A-4gbrA:
58.02
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2Y03_B_5FWB601_1
(BETA-1 ADRENERGIC
RECEPTOR)		 4gbr BETA-2 ADRENERGIC
RECEPTOR
(Homo
sapiens) 		6 / 12 TRP A 109
ASP A 113
VAL A 114
SER A 207
PHE A 262
TYR A 288
 None
CAU  A 500 (-3.0A)
CAU  A 500 (-3.5A)
CAU  A 500 (-4.1A)
CAU  A 500 (-4.6A)
CAU  A 500 (-4.6A)
 1.48A 2y03B-4gbrA:
39.0		 2y03B-4gbrA:
58.02
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2Y03_B_5FWB601_1
(BETA-1 ADRENERGIC
RECEPTOR)		 4gbr BETA-2 ADRENERGIC
RECEPTOR
(Homo
sapiens) 		6 / 12 TRP A 109
THR A 110
ASP A 113
VAL A 114
SER A 203
PHE A 261
 None
CAU  A 500 ( 4.0A)
CAU  A 500 (-3.0A)
CAU  A 500 (-3.5A)
CAU  A 500 (-3.3A)
CAU  A 500 (-4.2A)
 1.37A 2y03B-4gbrA:
39.0		 2y03B-4gbrA:
58.02
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2Y03_B_5FWB601_1
(BETA-1 ADRENERGIC
RECEPTOR)		 4gbr BETA-2 ADRENERGIC
RECEPTOR
(Homo
sapiens) 		10 / 12 TRP A 109
THR A 110
ASP A 113
VAL A 114
VAL A 117
PHE A 261
PHE A 262
ASN A 265
ASN A 284
TYR A 288
 None
CAU  A 500 ( 4.0A)
CAU  A 500 (-3.0A)
CAU  A 500 (-3.5A)
CAU  A 500 (-4.2A)
CAU  A 500 (-4.2A)
CAU  A 500 (-4.6A)
CAU  A 500 (-3.4A)
CAU  A 500 (-3.3A)
CAU  A 500 (-4.6A)
 0.56A 2y03B-4gbrA:
39.0		 2y03B-4gbrA:
58.02
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2Y03_B_5FWB601_1
(BETA-1 ADRENERGIC
RECEPTOR)		 4gbr BETA-2 ADRENERGIC
RECEPTOR
(Homo
sapiens) 		9 / 12 TRP A 109
THR A 110
ASP A 113
VAL A 114
VAL A 117
SER A 203
PHE A 261
PHE A 262
TYR A 288
 None
CAU  A 500 ( 4.0A)
CAU  A 500 (-3.0A)
CAU  A 500 (-3.5A)
CAU  A 500 (-4.2A)
CAU  A 500 (-3.3A)
CAU  A 500 (-4.2A)
CAU  A 500 (-4.6A)
CAU  A 500 (-4.6A)
 0.59A 2y03B-4gbrA:
39.0		 2y03B-4gbrA:
58.02
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2Y03_B_5FWB601_1
(BETA-1 ADRENERGIC
RECEPTOR)		 4gbr BETA-2 ADRENERGIC
RECEPTOR
(Homo
sapiens) 		5 / 12 TRP A 109
THR A 110
VAL A 114
SER A 203
SER A 207
 None
CAU  A 500 ( 4.0A)
CAU  A 500 (-3.5A)
CAU  A 500 (-3.3A)
CAU  A 500 (-4.1A)
 0.93A 2y03B-4gbrA:
39.0		 2y03B-4gbrA:
58.02
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2Y03_B_5FWB601_1
(BETA-1 ADRENERGIC
RECEPTOR)		 4gbr BETA-2 ADRENERGIC
RECEPTOR
(Homo
sapiens) 		5 / 12 TRP A 109
THR A 110
VAL A 114
SER A 207
ASN A 265
 None
CAU  A 500 ( 4.0A)
CAU  A 500 (-3.5A)
CAU  A 500 (-4.1A)
CAU  A 500 (-3.4A)
 0.90A 2y03B-4gbrA:
39.0		 2y03B-4gbrA:
58.02
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2Y03_B_5FWB601_1
(BETA-1 ADRENERGIC
RECEPTOR)		 4gbr BETA-2 ADRENERGIC
RECEPTOR
(Homo
sapiens) 		5 / 12 VAL A 117
PHE A 261
ASN A 265
ASN A 284
TYR A 288
 CAU  A 500 (-4.2A)
CAU  A 500 (-4.2A)
CAU  A 500 (-3.4A)
CAU  A 500 (-3.3A)
CAU  A 500 (-4.6A)
 1.28A 2y03B-4gbrA:
39.0		 2y03B-4gbrA:
58.02
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2Y04_A_68HA601_1
(BETA-1 ADRENERGIC
RECEPTOR)		 4gbr BETA-2 ADRENERGIC
RECEPTOR
(Homo
sapiens) 		11 / 11 TRP A 109
ASP A 113
VAL A 114
PHE A 193
SER A 203
SER A 207
PHE A 261
PHE A 262
ASN A 265
ASN A 284
TYR A 288
 None
CAU  A 500 (-3.0A)
CAU  A 500 (-3.5A)
CAU  A 500 (-4.5A)
CAU  A 500 (-3.3A)
CAU  A 500 (-4.1A)
CAU  A 500 (-4.2A)
CAU  A 500 (-4.6A)
CAU  A 500 (-3.4A)
CAU  A 500 (-3.3A)
CAU  A 500 (-4.6A)
 0.64A 2y04A-4gbrA:
38.9		 2y04A-4gbrA:
58.02
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2Y04_A_68HA601_1
(BETA-1 ADRENERGIC
RECEPTOR)		 4gbr BETA-2 ADRENERGIC
RECEPTOR
(Homo
sapiens) 		7 / 11 TRP A 109
ASP A 113
VAL A 114
SER A 203
PHE A 261
PHE A 262
ASN A 284
 None
CAU  A 500 (-3.0A)
CAU  A 500 (-3.5A)
CAU  A 500 (-3.3A)
CAU  A 500 (-4.2A)
CAU  A 500 (-4.6A)
CAU  A 500 (-3.3A)
 1.28A 2y04A-4gbrA:
38.9		 2y04A-4gbrA:
58.02
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2Y04_A_68HA601_1
(BETA-1 ADRENERGIC
RECEPTOR)		 4gbr BETA-2 ADRENERGIC
RECEPTOR
(Homo
sapiens) 		6 / 11 TRP A 109
ASP A 113
VAL A 114
SER A 207
PHE A 262
TYR A 288
 None
CAU  A 500 (-3.0A)
CAU  A 500 (-3.5A)
CAU  A 500 (-4.1A)
CAU  A 500 (-4.6A)
CAU  A 500 (-4.6A)
 1.36A 2y04A-4gbrA:
38.9		 2y04A-4gbrA:
58.02
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2Y04_A_68HA601_1
(BETA-1 ADRENERGIC
RECEPTOR)		 4gbr BETA-2 ADRENERGIC
RECEPTOR
(Homo
sapiens) 		5 / 11 VAL A 117
PHE A 261
ASN A 265
ASN A 284
TYR A 288
 CAU  A 500 (-4.2A)
CAU  A 500 (-4.2A)
CAU  A 500 (-3.4A)
CAU  A 500 (-3.3A)
CAU  A 500 (-4.6A)
 1.29A 2y04A-4gbrA:
38.9		 2y04A-4gbrA:
58.02
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2Y04_B_68HB601_1
(BETA-1 ADRENERGIC
RECEPTOR)		 4gbr BETA-2 ADRENERGIC
RECEPTOR
(Homo
sapiens) 		5 / 12 ASP A 113
VAL A 114
SER A 207
PHE A 262
TYR A 288
 CAU  A 500 (-3.0A)
CAU  A 500 (-3.5A)
CAU  A 500 (-4.1A)
CAU  A 500 (-4.6A)
CAU  A 500 (-4.6A)
 1.45A 2y04B-4gbrA:
39.0		 2y04B-4gbrA:
58.02
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2Y04_B_68HB601_1
(BETA-1 ADRENERGIC
RECEPTOR)		 4gbr BETA-2 ADRENERGIC
RECEPTOR
(Homo
sapiens) 		5 / 12 THR A 110
ASP A 113
VAL A 114
PHE A 193
PHE A 262
 CAU  A 500 ( 4.0A)
CAU  A 500 (-3.0A)
CAU  A 500 (-3.5A)
CAU  A 500 (-4.5A)
CAU  A 500 (-4.6A)
 1.34A 2y04B-4gbrA:
39.0		 2y04B-4gbrA:
58.02
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2Y04_B_68HB601_1
(BETA-1 ADRENERGIC
RECEPTOR)		 4gbr BETA-2 ADRENERGIC
RECEPTOR
(Homo
sapiens) 		8 / 12 TRP A 109
THR A 110
ASP A 113
VAL A 114
SER A 203
PHE A 261
PHE A 262
ASN A 284
 None
CAU  A 500 ( 4.0A)
CAU  A 500 (-3.0A)
CAU  A 500 (-3.5A)
CAU  A 500 (-3.3A)
CAU  A 500 (-4.2A)
CAU  A 500 (-4.6A)
CAU  A 500 (-3.3A)
 1.26A 2y04B-4gbrA:
39.0		 2y04B-4gbrA:
58.02
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2Y04_B_68HB601_1
(BETA-1 ADRENERGIC
RECEPTOR)		 4gbr BETA-2 ADRENERGIC
RECEPTOR
(Homo
sapiens) 		12 / 12 TRP A 109
THR A 110
ASP A 113
VAL A 114
VAL A 117
PHE A 193
SER A 203
SER A 207
PHE A 261
PHE A 262
ASN A 284
TYR A 288
 None
CAU  A 500 ( 4.0A)
CAU  A 500 (-3.0A)
CAU  A 500 (-3.5A)
CAU  A 500 (-4.2A)
CAU  A 500 (-4.5A)
CAU  A 500 (-3.3A)
CAU  A 500 (-4.1A)
CAU  A 500 (-4.2A)
CAU  A 500 (-4.6A)
CAU  A 500 (-3.3A)
CAU  A 500 (-4.6A)
 0.52A 2y04B-4gbrA:
39.0		 2y04B-4gbrA:
58.02
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3D4S_A_TIMA401_1
(BETA-2 ADRENERGIC
RECEPTOR/T4-LYSOZYME
CHIMERA)		 4gbr BETA-2 ADRENERGIC
RECEPTOR
(Homo
sapiens) 		8 / 12 TRP A 109
THR A 110
ASP A 113
VAL A 114
SER A 207
PHE A 262
ASN A 284
TYR A 288
 None
CAU  A 500 ( 4.0A)
CAU  A 500 (-3.0A)
CAU  A 500 (-3.5A)
CAU  A 500 (-4.1A)
CAU  A 500 (-4.6A)
CAU  A 500 (-3.3A)
CAU  A 500 (-4.6A)
 1.17A 3d4sA-4gbrA:
41.2		 3d4sA-4gbrA:
57.68
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3D4S_A_TIMA401_1
(BETA-2 ADRENERGIC
RECEPTOR/T4-LYSOZYME
CHIMERA)		 4gbr BETA-2 ADRENERGIC
RECEPTOR
(Homo
sapiens) 		12 / 12 TRP A 109
THR A 110
ASP A 113
VAL A 114
VAL A 117
SER A 203
TRP A 258
PHE A 262
ASN A 265
TYR A 280
ASN A 284
TYR A 288
 None
CAU  A 500 ( 4.0A)
CAU  A 500 (-3.0A)
CAU  A 500 (-3.5A)
CAU  A 500 (-4.2A)
CAU  A 500 (-3.3A)
None
CAU  A 500 (-4.6A)
CAU  A 500 (-3.4A)
None
CAU  A 500 (-3.3A)
CAU  A 500 (-4.6A)
 0.51A 3d4sA-4gbrA:
41.2		 3d4sA-4gbrA:
57.68
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3D4S_A_TIMA401_2
(BETA-2 ADRENERGIC
RECEPTOR/T4-LYSOZYME
CHIMERA)		 4gbr BETA-2 ADRENERGIC
RECEPTOR
(Homo
sapiens) 		3 / 3 THR A 118
SER A 207
PHE A 261
 CAU  A 500 ( 4.7A)
CAU  A 500 (-4.1A)
CAU  A 500 (-4.2A)
 0.15A 3d4sA-4gbrA:
41.2		 3d4sA-4gbrA:
57.68
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3NYA_A_JTZA1203_1
(BETA-2 ADRENERGIC
RECEPTOR, LYSOZYME)		 4gbr BETA-2 ADRENERGIC
RECEPTOR
(Homo
sapiens) 		9 / 12 TRP A 109
THR A 110
ASP A 113
VAL A 114
SER A 203
PHE A 261
PHE A 262
ASN A 284
TYR A 288
 None
CAU  A 500 ( 4.0A)
CAU  A 500 (-3.0A)
CAU  A 500 (-3.5A)
CAU  A 500 (-3.3A)
CAU  A 500 (-4.2A)
CAU  A 500 (-4.6A)
CAU  A 500 (-3.3A)
CAU  A 500 (-4.6A)
 1.15A 3nyaA-4gbrA:
40.8		 3nyaA-4gbrA:
57.68
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3NYA_A_JTZA1203_1
(BETA-2 ADRENERGIC
RECEPTOR, LYSOZYME)		 4gbr BETA-2 ADRENERGIC
RECEPTOR
(Homo
sapiens) 		12 / 12 TRP A 109
THR A 110
ASP A 113
VAL A 114
VAL A 117
SER A 203
SER A 207
PHE A 261
PHE A 262
ASN A 265
ASN A 284
TYR A 288
 None
CAU  A 500 ( 4.0A)
CAU  A 500 (-3.0A)
CAU  A 500 (-3.5A)
CAU  A 500 (-4.2A)
CAU  A 500 (-3.3A)
CAU  A 500 (-4.1A)
CAU  A 500 (-4.2A)
CAU  A 500 (-4.6A)
CAU  A 500 (-3.4A)
CAU  A 500 (-3.3A)
CAU  A 500 (-4.6A)
 0.47A 3nyaA-4gbrA:
40.8		 3nyaA-4gbrA:
57.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QFX_A_CP6A602_1
(BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 4gbr BETA-2 ADRENERGIC
RECEPTOR
(Homo
sapiens) 		5 / 12 VAL A 117
ALA A  78
ASP A  79
PHE A 254
ILE A 121
 CAU  A 500 (-4.2A)
None
None
None
None
 1.18A 3qfxA-4gbrA:
undetectable		 3qfxA-4gbrA:
21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RZE_A_D7VA1201_1
(HISTAMINE H1
RECEPTOR, LYSOZYME
CHIMERA)		 4gbr BETA-2 ADRENERGIC
RECEPTOR
(Homo
sapiens) 		6 / 12 ASP A 113
THR A 118
ILE A 121
TRP A 258
PHE A 262
TYR A 288
 CAU  A 500 (-3.0A)
CAU  A 500 ( 4.7A)
None
None
CAU  A 500 (-4.6A)
CAU  A 500 (-4.6A)
 0.73A 3rzeA-4gbrA:
31.0		 3rzeA-4gbrA:
25.37
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4AMJ_A_CVDA1359_1
(BETA-1 ADRENERGIC
RECEPTOR)		 4gbr BETA-2 ADRENERGIC
RECEPTOR
(Homo
sapiens) 		12 / 12 TRP A 109
ASP A 113
VAL A 114
VAL A 117
SER A 203
SER A 207
TRP A 258
PHE A 261
PHE A 262
ASN A 265
ASN A 284
TYR A 288
 None
CAU  A 500 (-3.0A)
CAU  A 500 (-3.5A)
CAU  A 500 (-4.2A)
CAU  A 500 (-3.3A)
CAU  A 500 (-4.1A)
None
CAU  A 500 (-4.2A)
CAU  A 500 (-4.6A)
CAU  A 500 (-3.4A)
CAU  A 500 (-3.3A)
CAU  A 500 (-4.6A)
 0.49A 4amjA-4gbrA:
39.5		 4amjA-4gbrA:
58.02
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4AMJ_B_CVDB1360_1
(BETA-1 ADRENERGIC
RECEPTOR)		 4gbr BETA-2 ADRENERGIC
RECEPTOR
(Homo
sapiens) 		11 / 12 TRP A 109
ASP A 113
VAL A 117
SER A 203
SER A 207
TRP A 258
PHE A 261
PHE A 262
ASN A 265
ASN A 284
TYR A 288
 None
CAU  A 500 (-3.0A)
CAU  A 500 (-4.2A)
CAU  A 500 (-3.3A)
CAU  A 500 (-4.1A)
None
CAU  A 500 (-4.2A)
CAU  A 500 (-4.6A)
CAU  A 500 (-3.4A)
CAU  A 500 (-3.3A)
CAU  A 500 (-4.6A)
 0.51A 4amjB-4gbrA:
39.4		 4amjB-4gbrA:
58.02
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4AMJ_B_CVDB1360_2
(BETA-1 ADRENERGIC
RECEPTOR)		 4gbr BETA-2 ADRENERGIC
RECEPTOR
(Homo
sapiens) 		4 / 4 VAL A 114
ASP A 192
TYR A 199
TRP A 285
 CAU  A 500 (-3.5A)
None
None
None
 0.52A 4amjB-4gbrA:
39.4		 4amjB-4gbrA:
58.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IAR_A_ERMA2001_2
(CHIMERA PROTEIN OF
HUMAN
5-HYDROXYTRYPTAMINE
RECEPTOR 1B AND E.
COLI SOLUBLE
CYTOCHROME B562)		 4gbr BETA-2 ADRENERGIC
RECEPTOR
(Homo
sapiens) 		4 / 7 TRP A 109
THR A 118
SER A 203
PHE A 262
 None
CAU  A 500 ( 4.7A)
CAU  A 500 (-3.3A)
CAU  A 500 (-4.6A)
 0.76A 4iarA-4gbrA:
29.5		 4iarA-4gbrA:
29.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IB4_A_ERMA2001_1
(CHIMERA PROTEIN OF
HUMAN
5-HYDROXYTRYPTAMINE
RECEPTOR 2B AND E.
COLI SOLUBLE
CYTOCHROME B562)		 4gbr BETA-2 ADRENERGIC
RECEPTOR
(Homo
sapiens) 		5 / 12 VAL A 114
TRP A 258
PHE A 261
PHE A 262
VAL A 269
 CAU  A 500 (-3.5A)
None
CAU  A 500 (-4.2A)
CAU  A 500 (-4.6A)
None
 0.65A 4ib4A-4gbrA:
27.3		 4ib4A-4gbrA:
29.05
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4LDO_A_ALEA1402_1
(LYSOZYME, BETA-2
ADRENERGIC RECEPTOR)		 4gbr BETA-2 ADRENERGIC
RECEPTOR
(Homo
sapiens) 		6 / 10 ASP A 113
VAL A 114
PHE A 193
SER A 203
SER A 207
PHE A 261
 CAU  A 500 (-3.0A)
CAU  A 500 (-3.5A)
CAU  A 500 (-4.5A)
CAU  A 500 (-3.3A)
CAU  A 500 (-4.1A)
CAU  A 500 (-4.2A)
 1.05A 4ldoA-4gbrA:
33.2		 4ldoA-4gbrA:
99.66
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4LDO_A_ALEA1402_1
(LYSOZYME, BETA-2
ADRENERGIC RECEPTOR)		 4gbr BETA-2 ADRENERGIC
RECEPTOR
(Homo
sapiens) 		6 / 10 ASP A 113
VAL A 114
PHE A 193
SER A 207
PHE A 261
ASN A 265
 CAU  A 500 (-3.0A)
CAU  A 500 (-3.5A)
CAU  A 500 (-4.5A)
CAU  A 500 (-4.1A)
CAU  A 500 (-4.2A)
CAU  A 500 (-3.4A)
 1.09A 4ldoA-4gbrA:
33.2		 4ldoA-4gbrA:
99.66
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4LDO_A_ALEA1402_1
(LYSOZYME, BETA-2
ADRENERGIC RECEPTOR)		 4gbr BETA-2 ADRENERGIC
RECEPTOR
(Homo
sapiens) 		7 / 10 ASP A 113
VAL A 114
VAL A 117
PHE A 193
PHE A 261
ASN A 265
TYR A 288
 CAU  A 500 (-3.0A)
CAU  A 500 (-3.5A)
CAU  A 500 (-4.2A)
CAU  A 500 (-4.5A)
CAU  A 500 (-4.2A)
CAU  A 500 (-3.4A)
CAU  A 500 (-4.6A)
 0.82A 4ldoA-4gbrA:
33.2		 4ldoA-4gbrA:
99.66
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4LDO_A_ALEA1402_1
(LYSOZYME, BETA-2
ADRENERGIC RECEPTOR)		 4gbr BETA-2 ADRENERGIC
RECEPTOR
(Homo
sapiens) 		7 / 10 ASP A 113
VAL A 114
VAL A 117
PHE A 193
SER A 203
PHE A 261
TYR A 288
 CAU  A 500 (-3.0A)
CAU  A 500 (-3.5A)
CAU  A 500 (-4.2A)
CAU  A 500 (-4.5A)
CAU  A 500 (-3.3A)
CAU  A 500 (-4.2A)
CAU  A 500 (-4.6A)
 0.86A 4ldoA-4gbrA:
33.2		 4ldoA-4gbrA:
99.66
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4LDO_A_ALEA1402_1
(LYSOZYME, BETA-2
ADRENERGIC RECEPTOR)		 4gbr BETA-2 ADRENERGIC
RECEPTOR
(Homo
sapiens) 		7 / 10 ASP A 113
VAL A 114
VAL A 117
PHE A 261
ASN A 265
ASN A 284
TYR A 288
 CAU  A 500 (-3.0A)
CAU  A 500 (-3.5A)
CAU  A 500 (-4.2A)
CAU  A 500 (-4.2A)
CAU  A 500 (-3.4A)
CAU  A 500 (-3.3A)
CAU  A 500 (-4.6A)
 0.80A 4ldoA-4gbrA:
33.2		 4ldoA-4gbrA:
99.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FSA_B_X2NB590_2
(CYP51 VARIANT1)		 4gbr BETA-2 ADRENERGIC
RECEPTOR
(Homo
sapiens) 		3 / 3 PRO A 211
LEU A 259
SER A 207
 None
None
CAU  A 500 (-4.1A)
 0.82A 5fsaB-4gbrA:
0.0		 5fsaB-4gbrA:
20.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6A93_A_8NUA3001_0
(5-HYDROXYTRYPTAMINE
RECEPTOR 2A,SOLUBLE
CYTOCHROME B562)		 4gbr BETA-2 ADRENERGIC
RECEPTOR
(Homo
sapiens) 		8 / 12 TRP A 109
THR A 118
ILE A 121
PHE A 254
TRP A 258
PHE A 261
PHE A 262
TYR A 288
 None
CAU  A 500 ( 4.7A)
None
None
None
CAU  A 500 (-4.2A)
CAU  A 500 (-4.6A)
CAU  A 500 (-4.6A)
 0.67A 6a93A-4gbrA:
30.0		 6a93A-4gbrA:
29.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6A93_B_8NUB3001_0
(5-HYDROXYTRYPTAMINE
RECEPTOR 2A,SOLUBLE
CYTOCHROME B562)		 4gbr BETA-2 ADRENERGIC
RECEPTOR
(Homo
sapiens) 		6 / 12 TRP A 109
VAL A 114
THR A 118
TRP A 258
PHE A 261
PHE A 262
 None
CAU  A 500 (-3.5A)
CAU  A 500 ( 4.7A)
None
CAU  A 500 (-4.2A)
CAU  A 500 (-4.6A)
 0.51A 6a93B-4gbrA:
31.1		 6a93B-4gbrA:
29.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6A93_B_8NUB3001_1
(5-HYDROXYTRYPTAMINE
RECEPTOR 2A,SOLUBLE
CYTOCHROME B562)		 4gbr BETA-2 ADRENERGIC
RECEPTOR
(Homo
sapiens) 		4 / 5 ASP A 113
ILE A 121
PHE A 254
TYR A 288
 CAU  A 500 (-3.0A)
None
None
CAU  A 500 (-4.6A)
 0.59A 6a93B-4gbrA:
31.1		 6a93B-4gbrA:
29.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6A94_A_ZOTA3001_0
(5-HYDROXYTRYPTAMINE
RECEPTOR 2A,SOLUBLE
CYTOCHROME B562)		 4gbr BETA-2 ADRENERGIC
RECEPTOR
(Homo
sapiens) 		7 / 12 TRP A 109
SER A 207
PHE A 254
TRP A 258
PHE A 261
PHE A 262
ASN A 265
 None
CAU  A 500 (-4.1A)
None
None
CAU  A 500 (-4.2A)
CAU  A 500 (-4.6A)
CAU  A 500 (-3.4A)
 0.97A 6a94A-4gbrA:
32.0		 6a94A-4gbrA:
29.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6A94_B_ZOTB3001_0
(5-HYDROXYTRYPTAMINE
RECEPTOR 2A,SOLUBLE
CYTOCHROME B562)		 4gbr BETA-2 ADRENERGIC
RECEPTOR
(Homo
sapiens) 		7 / 12 VAL A 114
THR A 118
SER A 207
PHE A 254
TRP A 258
PHE A 261
PHE A 262
 CAU  A 500 (-3.5A)
CAU  A 500 ( 4.7A)
CAU  A 500 (-4.1A)
None
None
CAU  A 500 (-4.2A)
CAU  A 500 (-4.6A)
 0.63A 6a94B-4gbrA:
31.4		 6a94B-4gbrA:
29.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CM4_A_8NUA2001_0
(D(2) DOPAMINE
RECEPTOR, ENDOLYSIN
CHIMERA)		 4gbr BETA-2 ADRENERGIC
RECEPTOR
(Homo
sapiens) 		5 / 12 PHE A 254
TRP A 258
PHE A 262
TYR A 280
TYR A 288
 None
None
CAU  A 500 (-4.6A)
None
CAU  A 500 (-4.6A)
 0.64A 6cm4A-4gbrA:
30.5		 6cm4A-4gbrA:
25.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CM4_A_8NUA2001_0
(D(2) DOPAMINE
RECEPTOR, ENDOLYSIN
CHIMERA)		 4gbr BETA-2 ADRENERGIC
RECEPTOR
(Homo
sapiens) 		6 / 12 VAL A 114
THR A 118
PHE A 254
TRP A 258
PHE A 262
TYR A 288
 CAU  A 500 (-3.5A)
CAU  A 500 ( 4.7A)
None
None
CAU  A 500 (-4.6A)
CAU  A 500 (-4.6A)
 0.74A 6cm4A-4gbrA:
30.5		 6cm4A-4gbrA:
25.59
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6DRX_A_H8GA1201_0
(5HT2B RECEPTOR, BRIL
CHIMERA)		 4gbr BETA-2 ADRENERGIC
RECEPTOR
(Homo
sapiens) 		7 / 12 TRP A 109
VAL A 114
THR A 118
TRP A 258
PHE A 261
ASN A 265
TYR A 288
 None
CAU  A 500 (-3.5A)
CAU  A 500 ( 4.7A)
None
CAU  A 500 (-4.2A)
CAU  A 500 (-3.4A)
CAU  A 500 (-4.6A)
 0.93A 6drxA-4gbrA:
28.8		 6drxA-4gbrA:
30.19
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6DRY_A_H8DA2001_0
(5HT2B RECEPTOR, BRIL
CHIMERA)		 4gbr BETA-2 ADRENERGIC
RECEPTOR
(Homo
sapiens) 		5 / 11 ASP A 113
VAL A 114
THR A 118
PHE A 261
TYR A 288
 CAU  A 500 (-3.0A)
CAU  A 500 (-3.5A)
CAU  A 500 ( 4.7A)
CAU  A 500 (-4.2A)
CAU  A 500 (-4.6A)
 0.84A 6dryA-4gbrA:
26.6		 6dryA-4gbrA:
30.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6DRZ_A_H8JA1206_0
(5HT2B RECEPTOR, BRIL
CHIMERA)		 4gbr BETA-2 ADRENERGIC
RECEPTOR
(Homo
sapiens) 		6 / 12 VAL A 114
THR A 118
PHE A 261
PHE A 262
ASN A 265
TYR A 288
 CAU  A 500 (-3.5A)
CAU  A 500 ( 4.7A)
CAU  A 500 (-4.2A)
CAU  A 500 (-4.6A)
CAU  A 500 (-3.4A)
CAU  A 500 (-4.6A)
 0.79A 6drzA-4gbrA:
28.8		 6drzA-4gbrA:
30.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6H7J_A_5FWA401_0
(BETA-1 ADRENERGIC
RECEPTOR)		 4gbr BETA-2 ADRENERGIC
RECEPTOR
(Homo
sapiens) 		5 / 12 THR A 110
VAL A 114
SER A 204
PHE A 262
ASN A 265
 CAU  A 500 ( 4.0A)
CAU  A 500 (-3.5A)
None
CAU  A 500 (-4.6A)
CAU  A 500 (-3.4A)
 0.92A 6h7jA-4gbrA:
32.1		 6h7jA-4gbrA:
59.76
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6H7J_A_5FWA401_0
(BETA-1 ADRENERGIC
RECEPTOR)		 4gbr BETA-2 ADRENERGIC
RECEPTOR
(Homo
sapiens) 		5 / 12 THR A 110
VAL A 114
SER A 204
SER A 207
ASN A 265
 CAU  A 500 ( 4.0A)
CAU  A 500 (-3.5A)
None
CAU  A 500 (-4.1A)
CAU  A 500 (-3.4A)
 0.97A 6h7jA-4gbrA:
32.1		 6h7jA-4gbrA:
59.76
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6H7J_A_5FWA401_0
(BETA-1 ADRENERGIC
RECEPTOR)		 4gbr BETA-2 ADRENERGIC
RECEPTOR
(Homo
sapiens) 		9 / 12 TRP A 109
THR A 110
ASP A 113
VAL A 114
PHE A 261
PHE A 262
ASN A 265
ASN A 284
TYR A 288
 None
CAU  A 500 ( 4.0A)
CAU  A 500 (-3.0A)
CAU  A 500 (-3.5A)
CAU  A 500 (-4.2A)
CAU  A 500 (-4.6A)
CAU  A 500 (-3.4A)
CAU  A 500 (-3.3A)
CAU  A 500 (-4.6A)
 0.66A 6h7jA-4gbrA:
32.1		 6h7jA-4gbrA:
59.76
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6H7J_A_5FWA401_0
(BETA-1 ADRENERGIC
RECEPTOR)		 4gbr BETA-2 ADRENERGIC
RECEPTOR
(Homo
sapiens) 		8 / 12 TRP A 109
THR A 110
ASP A 113
VAL A 114
SER A 203
PHE A 261
PHE A 262
TYR A 288
 None
CAU  A 500 ( 4.0A)
CAU  A 500 (-3.0A)
CAU  A 500 (-3.5A)
CAU  A 500 (-3.3A)
CAU  A 500 (-4.2A)
CAU  A 500 (-4.6A)
CAU  A 500 (-4.6A)
 0.68A 6h7jA-4gbrA:
32.1		 6h7jA-4gbrA:
59.76
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6H7J_A_5FWA401_0
(BETA-1 ADRENERGIC
RECEPTOR)		 4gbr BETA-2 ADRENERGIC
RECEPTOR
(Homo
sapiens) 		7 / 12 TRP A 109
THR A 110
ASP A 113
VAL A 114
SER A 207
PHE A 262
TYR A 288
 None
CAU  A 500 ( 4.0A)
CAU  A 500 (-3.0A)
CAU  A 500 (-3.5A)
CAU  A 500 (-4.1A)
CAU  A 500 (-4.6A)
CAU  A 500 (-4.6A)
 1.28A 6h7jA-4gbrA:
32.1		 6h7jA-4gbrA:
59.76
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6H7J_A_5FWA401_0
(BETA-1 ADRENERGIC
RECEPTOR)		 4gbr BETA-2 ADRENERGIC
RECEPTOR
(Homo
sapiens) 		5 / 12 TRP A 109
THR A 110
VAL A 114
SER A 203
SER A 207
 None
CAU  A 500 ( 4.0A)
CAU  A 500 (-3.5A)
CAU  A 500 (-3.3A)
CAU  A 500 (-4.1A)
 0.94A 6h7jA-4gbrA:
32.1		 6h7jA-4gbrA:
59.76
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6H7J_A_5FWA401_0
(BETA-1 ADRENERGIC
RECEPTOR)		 4gbr BETA-2 ADRENERGIC
RECEPTOR
(Homo
sapiens) 		5 / 12 TRP A 109
THR A 110
VAL A 114
SER A 207
ASN A 265
 None
CAU  A 500 ( 4.0A)
CAU  A 500 (-3.5A)
CAU  A 500 (-4.1A)
CAU  A 500 (-3.4A)
 0.98A 6h7jA-4gbrA:
32.1		 6h7jA-4gbrA:
59.76
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6H7J_B_5FWB402_0
(BETA-1 ADRENERGIC
RECEPTOR)		 4gbr BETA-2 ADRENERGIC
RECEPTOR
(Homo
sapiens) 		5 / 12 THR A 110
VAL A 114
SER A 204
PHE A 262
ASN A 265
 CAU  A 500 ( 4.0A)
CAU  A 500 (-3.5A)
None
CAU  A 500 (-4.6A)
CAU  A 500 (-3.4A)
 0.91A 6h7jB-4gbrA:
32.8		 6h7jB-4gbrA:
59.76
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6H7J_B_5FWB402_0
(BETA-1 ADRENERGIC
RECEPTOR)		 4gbr BETA-2 ADRENERGIC
RECEPTOR
(Homo
sapiens) 		5 / 12 THR A 110
VAL A 114
SER A 204
SER A 207
ASN A 265
 CAU  A 500 ( 4.0A)
CAU  A 500 (-3.5A)
None
CAU  A 500 (-4.1A)
CAU  A 500 (-3.4A)
 0.97A 6h7jB-4gbrA:
32.8		 6h7jB-4gbrA:
59.76
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6H7J_B_5FWB402_0
(BETA-1 ADRENERGIC
RECEPTOR)		 4gbr BETA-2 ADRENERGIC
RECEPTOR
(Homo
sapiens) 		9 / 12 TRP A 109
THR A 110
ASP A 113
VAL A 114
PHE A 261
PHE A 262
ASN A 265
ASN A 284
TYR A 288
 None
CAU  A 500 ( 4.0A)
CAU  A 500 (-3.0A)
CAU  A 500 (-3.5A)
CAU  A 500 (-4.2A)
CAU  A 500 (-4.6A)
CAU  A 500 (-3.4A)
CAU  A 500 (-3.3A)
CAU  A 500 (-4.6A)
 0.65A 6h7jB-4gbrA:
32.8		 6h7jB-4gbrA:
59.76
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6H7J_B_5FWB402_0
(BETA-1 ADRENERGIC
RECEPTOR)		 4gbr BETA-2 ADRENERGIC
RECEPTOR
(Homo
sapiens) 		8 / 12 TRP A 109
THR A 110
ASP A 113
VAL A 114
SER A 203
PHE A 261
PHE A 262
TYR A 288
 None
CAU  A 500 ( 4.0A)
CAU  A 500 (-3.0A)
CAU  A 500 (-3.5A)
CAU  A 500 (-3.3A)
CAU  A 500 (-4.2A)
CAU  A 500 (-4.6A)
CAU  A 500 (-4.6A)
 0.68A 6h7jB-4gbrA:
32.8		 6h7jB-4gbrA:
59.76
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6H7J_B_5FWB402_0
(BETA-1 ADRENERGIC
RECEPTOR)		 4gbr BETA-2 ADRENERGIC
RECEPTOR
(Homo
sapiens) 		7 / 12 TRP A 109
THR A 110
ASP A 113
VAL A 114
SER A 207
PHE A 262
TYR A 288
 None
CAU  A 500 ( 4.0A)
CAU  A 500 (-3.0A)
CAU  A 500 (-3.5A)
CAU  A 500 (-4.1A)
CAU  A 500 (-4.6A)
CAU  A 500 (-4.6A)
 1.27A 6h7jB-4gbrA:
32.8		 6h7jB-4gbrA:
59.76
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6H7J_B_5FWB402_0
(BETA-1 ADRENERGIC
RECEPTOR)		 4gbr BETA-2 ADRENERGIC
RECEPTOR
(Homo
sapiens) 		5 / 12 TRP A 109
THR A 110
VAL A 114
SER A 203
SER A 207
 None
CAU  A 500 ( 4.0A)
CAU  A 500 (-3.5A)
CAU  A 500 (-3.3A)
CAU  A 500 (-4.1A)
 0.96A 6h7jB-4gbrA:
32.8		 6h7jB-4gbrA:
59.76
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6H7J_B_5FWB402_0
(BETA-1 ADRENERGIC
RECEPTOR)		 4gbr BETA-2 ADRENERGIC
RECEPTOR
(Homo
sapiens) 		5 / 12 TRP A 109
THR A 110
VAL A 114
SER A 207
ASN A 265
 None
CAU  A 500 ( 4.0A)
CAU  A 500 (-3.5A)
CAU  A 500 (-4.1A)
CAU  A 500 (-3.4A)
 0.98A 6h7jB-4gbrA:
32.8		 6h7jB-4gbrA:
59.76
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6H7L_A_Y00A406_0
(BETA-1 ADRENERGIC
RECEPTOR)		 4gbr BETA-2 ADRENERGIC
RECEPTOR
(Homo
sapiens) 		6 / 12 TRP A 109
ASP A 113
VAL A 114
SER A 207
TRP A 285
TYR A 288
 None
CAU  A 500 (-3.0A)
CAU  A 500 (-3.5A)
CAU  A 500 (-4.1A)
None
CAU  A 500 (-4.6A)
 1.26A 6h7lA-4gbrA:
32.3		 6h7lA-4gbrA:
59.76
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6H7L_A_Y00A406_0
(BETA-1 ADRENERGIC
RECEPTOR)		 4gbr BETA-2 ADRENERGIC
RECEPTOR
(Homo
sapiens) 		8 / 12 TRP A 109
THR A 110
ASP A 113
VAL A 114
ASN A 265
ASN A 284
TRP A 285
TYR A 288
 None
CAU  A 500 ( 4.0A)
CAU  A 500 (-3.0A)
CAU  A 500 (-3.5A)
CAU  A 500 (-3.4A)
CAU  A 500 (-3.3A)
None
CAU  A 500 (-4.6A)
 0.73A 6h7lA-4gbrA:
32.3		 6h7lA-4gbrA:
59.76
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6H7L_A_Y00A406_0
(BETA-1 ADRENERGIC
RECEPTOR)		 4gbr BETA-2 ADRENERGIC
RECEPTOR
(Homo
sapiens) 		6 / 12 TRP A 109
THR A 110
ASP A 113
VAL A 114
SER A 203
SER A 207
 None
CAU  A 500 ( 4.0A)
CAU  A 500 (-3.0A)
CAU  A 500 (-3.5A)
CAU  A 500 (-3.3A)
CAU  A 500 (-4.1A)
 0.87A 6h7lA-4gbrA:
32.3		 6h7lA-4gbrA:
59.76
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6H7L_A_Y00A406_0
(BETA-1 ADRENERGIC
RECEPTOR)		 4gbr BETA-2 ADRENERGIC
RECEPTOR
(Homo
sapiens) 		7 / 12 TRP A 109
THR A 110
ASP A 113
VAL A 114
SER A 203
TRP A 285
TYR A 288
 None
CAU  A 500 ( 4.0A)
CAU  A 500 (-3.0A)
CAU  A 500 (-3.5A)
CAU  A 500 (-3.3A)
None
CAU  A 500 (-4.6A)
 0.76A 6h7lA-4gbrA:
32.3		 6h7lA-4gbrA:
59.76
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6H7L_A_Y00A406_0
(BETA-1 ADRENERGIC
RECEPTOR)		 4gbr BETA-2 ADRENERGIC
RECEPTOR
(Homo
sapiens) 		6 / 12 TRP A 109
THR A 110
ASP A 113
VAL A 114
SER A 207
ASN A 265
 None
CAU  A 500 ( 4.0A)
CAU  A 500 (-3.0A)
CAU  A 500 (-3.5A)
CAU  A 500 (-4.1A)
CAU  A 500 (-3.4A)
 0.94A 6h7lA-4gbrA:
32.3		 6h7lA-4gbrA:
59.76
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6H7L_A_Y00A406_1
(BETA-1 ADRENERGIC
RECEPTOR)		 4gbr BETA-2 ADRENERGIC
RECEPTOR
(Homo
sapiens) 		4 / 6 GLY A  90
VAL A 117
PHE A 193
PHE A 262
 None
CAU  A 500 (-4.2A)
CAU  A 500 (-4.5A)
CAU  A 500 (-4.6A)
 0.66A 6h7lA-4gbrA:
32.3		 6h7lA-4gbrA:
59.76
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6H7L_A_Y00A406_1
(BETA-1 ADRENERGIC
RECEPTOR)		 4gbr BETA-2 ADRENERGIC
RECEPTOR
(Homo
sapiens) 		4 / 6 GLY A  90
VAL A 117
PHE A 261
PHE A 262
 None
CAU  A 500 (-4.2A)
CAU  A 500 (-4.2A)
CAU  A 500 (-4.6A)
 0.46A 6h7lA-4gbrA:
32.3		 6h7lA-4gbrA:
59.76
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6H7L_B_Y00B405_0
(BETA-1 ADRENERGIC
RECEPTOR)		 4gbr BETA-2 ADRENERGIC
RECEPTOR
(Homo
sapiens) 		6 / 12 TRP A 109
ASP A 113
VAL A 114
SER A 207
TRP A 285
TYR A 288
 None
CAU  A 500 (-3.0A)
CAU  A 500 (-3.5A)
CAU  A 500 (-4.1A)
None
CAU  A 500 (-4.6A)
 1.27A 6h7lB-4gbrA:
32.6		 6h7lB-4gbrA:
59.76
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6H7L_B_Y00B405_0
(BETA-1 ADRENERGIC
RECEPTOR)		 4gbr BETA-2 ADRENERGIC
RECEPTOR
(Homo
sapiens) 		8 / 12 TRP A 109
THR A 110
ASP A 113
VAL A 114
ASN A 265
ASN A 284
TRP A 285
TYR A 288
 None
CAU  A 500 ( 4.0A)
CAU  A 500 (-3.0A)
CAU  A 500 (-3.5A)
CAU  A 500 (-3.4A)
CAU  A 500 (-3.3A)
None
CAU  A 500 (-4.6A)
 0.73A 6h7lB-4gbrA:
32.6		 6h7lB-4gbrA:
59.76
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6H7L_B_Y00B405_0
(BETA-1 ADRENERGIC
RECEPTOR)		 4gbr BETA-2 ADRENERGIC
RECEPTOR
(Homo
sapiens) 		6 / 12 TRP A 109
THR A 110
ASP A 113
VAL A 114
SER A 203
SER A 207
 None
CAU  A 500 ( 4.0A)
CAU  A 500 (-3.0A)
CAU  A 500 (-3.5A)
CAU  A 500 (-3.3A)
CAU  A 500 (-4.1A)
 0.88A 6h7lB-4gbrA:
32.6		 6h7lB-4gbrA:
59.76
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6H7L_B_Y00B405_0
(BETA-1 ADRENERGIC
RECEPTOR)		 4gbr BETA-2 ADRENERGIC
RECEPTOR
(Homo
sapiens) 		7 / 12 TRP A 109
THR A 110
ASP A 113
VAL A 114
SER A 203
TRP A 285
TYR A 288
 None
CAU  A 500 ( 4.0A)
CAU  A 500 (-3.0A)
CAU  A 500 (-3.5A)
CAU  A 500 (-3.3A)
None
CAU  A 500 (-4.6A)
 0.76A 6h7lB-4gbrA:
32.6		 6h7lB-4gbrA:
59.76
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6H7L_B_Y00B405_0
(BETA-1 ADRENERGIC
RECEPTOR)		 4gbr BETA-2 ADRENERGIC
RECEPTOR
(Homo
sapiens) 		6 / 12 TRP A 109
THR A 110
ASP A 113
VAL A 114
SER A 207
ASN A 265
 None
CAU  A 500 ( 4.0A)
CAU  A 500 (-3.0A)
CAU  A 500 (-3.5A)
CAU  A 500 (-4.1A)
CAU  A 500 (-3.4A)
 0.93A 6h7lB-4gbrA:
32.6		 6h7lB-4gbrA:
59.76
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6H7L_B_Y00B405_1
(BETA-1 ADRENERGIC
RECEPTOR)		 4gbr BETA-2 ADRENERGIC
RECEPTOR
(Homo
sapiens) 		4 / 6 GLY A  90
VAL A 117
PHE A 193
PHE A 262
 None
CAU  A 500 (-4.2A)
CAU  A 500 (-4.5A)
CAU  A 500 (-4.6A)
 0.68A 6h7lB-4gbrA:
32.6		 6h7lB-4gbrA:
59.76
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6H7L_B_Y00B405_1
(BETA-1 ADRENERGIC
RECEPTOR)		 4gbr BETA-2 ADRENERGIC
RECEPTOR
(Homo
sapiens) 		4 / 6 GLY A  90
VAL A 117
PHE A 261
PHE A 262
 None
CAU  A 500 (-4.2A)
CAU  A 500 (-4.2A)
CAU  A 500 (-4.6A)
 0.46A 6h7lB-4gbrA:
32.6		 6h7lB-4gbrA:
59.76
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6H7M_A_68HA504_0
(BETA-1 ADRENERGIC
RECEPTOR)		 4gbr BETA-2 ADRENERGIC
RECEPTOR
(Homo
sapiens) 		10 / 12 TRP A 109
THR A 110
ASP A 113
VAL A 114
PHE A 193
PHE A 261
PHE A 262
ASN A 265
ASN A 284
TYR A 288
 None
CAU  A 500 ( 4.0A)
CAU  A 500 (-3.0A)
CAU  A 500 (-3.5A)
CAU  A 500 (-4.5A)
CAU  A 500 (-4.2A)
CAU  A 500 (-4.6A)
CAU  A 500 (-3.4A)
CAU  A 500 (-3.3A)
CAU  A 500 (-4.6A)
 0.61A 6h7mA-4gbrA:
32.5		 6h7mA-4gbrA:
59.76
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6H7M_A_68HA504_0
(BETA-1 ADRENERGIC
RECEPTOR)		 4gbr BETA-2 ADRENERGIC
RECEPTOR
(Homo
sapiens) 		10 / 12 TRP A 109
THR A 110
ASP A 113
VAL A 114
PHE A 193
SER A 203
PHE A 261
PHE A 262
ASN A 284
TYR A 288
 None
CAU  A 500 ( 4.0A)
CAU  A 500 (-3.0A)
CAU  A 500 (-3.5A)
CAU  A 500 (-4.5A)
CAU  A 500 (-3.3A)
CAU  A 500 (-4.2A)
CAU  A 500 (-4.6A)
CAU  A 500 (-3.3A)
CAU  A 500 (-4.6A)
 0.72A 6h7mA-4gbrA:
32.5		 6h7mA-4gbrA:
59.76
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6H7M_A_68HA504_0
(BETA-1 ADRENERGIC
RECEPTOR)		 4gbr BETA-2 ADRENERGIC
RECEPTOR
(Homo
sapiens) 		7 / 12 TRP A 109
THR A 110
ASP A 113
VAL A 114
SER A 207
PHE A 262
TYR A 288
 None
CAU  A 500 ( 4.0A)
CAU  A 500 (-3.0A)
CAU  A 500 (-3.5A)
CAU  A 500 (-4.1A)
CAU  A 500 (-4.6A)
CAU  A 500 (-4.6A)
 1.29A 6h7mA-4gbrA:
32.5		 6h7mA-4gbrA:
59.76
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6H7M_A_68HA504_0
(BETA-1 ADRENERGIC
RECEPTOR)		 4gbr BETA-2 ADRENERGIC
RECEPTOR
(Homo
sapiens) 		7 / 12 TRP A 109
THR A 110
VAL A 114
PHE A 193
SER A 207
PHE A 261
ASN A 265
 None
CAU  A 500 ( 4.0A)
CAU  A 500 (-3.5A)
CAU  A 500 (-4.5A)
CAU  A 500 (-4.1A)
CAU  A 500 (-4.2A)
CAU  A 500 (-3.4A)
 0.83A 6h7mA-4gbrA:
32.5		 6h7mA-4gbrA:
59.76
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6H7M_A_68HA504_0
(BETA-1 ADRENERGIC
RECEPTOR)		 4gbr BETA-2 ADRENERGIC
RECEPTOR
(Homo
sapiens) 		5 / 12 VAL A 117
PHE A 261
ASN A 265
ASN A 284
TYR A 288
 CAU  A 500 (-4.2A)
CAU  A 500 (-4.2A)
CAU  A 500 (-3.4A)
CAU  A 500 (-3.3A)
CAU  A 500 (-4.6A)
 1.38A 6h7mA-4gbrA:
32.5		 6h7mA-4gbrA:
59.76
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6H7M_B_68HB405_0
(BETA-1 ADRENERGIC
RECEPTOR)		 4gbr BETA-2 ADRENERGIC
RECEPTOR
(Homo
sapiens) 		6 / 12 TRP A 109
ASP A 113
VAL A 114
SER A 207
PHE A 262
TYR A 288
 None
CAU  A 500 (-3.0A)
CAU  A 500 (-3.5A)
CAU  A 500 (-4.1A)
CAU  A 500 (-4.6A)
CAU  A 500 (-4.6A)
 1.29A 6h7mB-4gbrA:
32.8		 6h7mB-4gbrA:
59.76
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6H7M_B_68HB405_0
(BETA-1 ADRENERGIC
RECEPTOR)		 4gbr BETA-2 ADRENERGIC
RECEPTOR
(Homo
sapiens) 		10 / 12 TRP A 109
ASP A 113
VAL A 114
VAL A 117
PHE A 193
PHE A 261
PHE A 262
ASN A 265
ASN A 284
TYR A 288
 None
CAU  A 500 (-3.0A)
CAU  A 500 (-3.5A)
CAU  A 500 (-4.2A)
CAU  A 500 (-4.5A)
CAU  A 500 (-4.2A)
CAU  A 500 (-4.6A)
CAU  A 500 (-3.4A)
CAU  A 500 (-3.3A)
CAU  A 500 (-4.6A)
 0.64A 6h7mB-4gbrA:
32.8		 6h7mB-4gbrA:
59.76
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6H7M_B_68HB405_0
(BETA-1 ADRENERGIC
RECEPTOR)		 4gbr BETA-2 ADRENERGIC
RECEPTOR
(Homo
sapiens) 		10 / 12 TRP A 109
ASP A 113
VAL A 114
VAL A 117
PHE A 193
SER A 203
PHE A 261
PHE A 262
ASN A 284
TYR A 288
 None
CAU  A 500 (-3.0A)
CAU  A 500 (-3.5A)
CAU  A 500 (-4.2A)
CAU  A 500 (-4.5A)
CAU  A 500 (-3.3A)
CAU  A 500 (-4.2A)
CAU  A 500 (-4.6A)
CAU  A 500 (-3.3A)
CAU  A 500 (-4.6A)
 0.75A 6h7mB-4gbrA:
32.8		 6h7mB-4gbrA:
59.76
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6H7M_B_68HB405_0
(BETA-1 ADRENERGIC
RECEPTOR)		 4gbr BETA-2 ADRENERGIC
RECEPTOR
(Homo
sapiens) 		8 / 12 TRP A 109
VAL A 114
VAL A 117
PHE A 193
SER A 207
PHE A 261
PHE A 262
ASN A 265
 None
CAU  A 500 (-3.5A)
CAU  A 500 (-4.2A)
CAU  A 500 (-4.5A)
CAU  A 500 (-4.1A)
CAU  A 500 (-4.2A)
CAU  A 500 (-4.6A)
CAU  A 500 (-3.4A)
 0.82A 6h7mB-4gbrA:
32.8		 6h7mB-4gbrA:
59.76
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6H7M_B_68HB405_0
(BETA-1 ADRENERGIC
RECEPTOR)		 4gbr BETA-2 ADRENERGIC
RECEPTOR
(Homo
sapiens) 		5 / 12 VAL A 117
PHE A 261
ASN A 265
ASN A 284
TYR A 288
 CAU  A 500 (-4.2A)
CAU  A 500 (-4.2A)
CAU  A 500 (-3.4A)
CAU  A 500 (-3.3A)
CAU  A 500 (-4.6A)
 1.38A 6h7mB-4gbrA:
32.8		 6h7mB-4gbrA:
59.76
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6IBL_A_H98A501_0
(THIOREDOXIN 1,BETA-1
ADRENERGIC RECEPTOR)		 4gbr BETA-2 ADRENERGIC
RECEPTOR
(Homo
sapiens) 		10 / 12 TRP A 109
THR A 110
VAL A 114
VAL A 117
ASP A 192
PHE A 193
TRP A 258
PHE A 261
PHE A 262
TYR A 288
 None
CAU  A 500 ( 4.0A)
CAU  A 500 (-3.5A)
CAU  A 500 (-4.2A)
None
CAU  A 500 (-4.5A)
None
CAU  A 500 (-4.2A)
CAU  A 500 (-4.6A)
CAU  A 500 (-4.6A)
 0.72A 6iblA-4gbrA:
32.4		 6iblA-4gbrA:
50.65
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6IBL_A_H98A501_0
(THIOREDOXIN 1,BETA-1
ADRENERGIC RECEPTOR)		 4gbr BETA-2 ADRENERGIC
RECEPTOR
(Homo
sapiens) 		10 / 12 TRP A 109
THR A 110
VAL A 114
VAL A 117
ASP A 192
TRP A 258
PHE A 261
PHE A 262
ASN A 265
TYR A 288
 None
CAU  A 500 ( 4.0A)
CAU  A 500 (-3.5A)
CAU  A 500 (-4.2A)
None
None
CAU  A 500 (-4.2A)
CAU  A 500 (-4.6A)
CAU  A 500 (-3.4A)
CAU  A 500 (-4.6A)
 0.71A 6iblA-4gbrA:
32.4		 6iblA-4gbrA:
50.65
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6IBL_B_H98B501_0
(THIOREDOXIN 1,BETA-1
ADRENERGIC RECEPTOR)		 4gbr BETA-2 ADRENERGIC
RECEPTOR
(Homo
sapiens) 		11 / 12 TRP A 109
THR A 110
VAL A 114
VAL A 117
ASP A 192
PHE A 193
TRP A 258
PHE A 261
PHE A 262
ASN A 265
TYR A 288
 None
CAU  A 500 ( 4.0A)
CAU  A 500 (-3.5A)
CAU  A 500 (-4.2A)
None
CAU  A 500 (-4.5A)
None
CAU  A 500 (-4.2A)
CAU  A 500 (-4.6A)
CAU  A 500 (-3.4A)
CAU  A 500 (-4.6A)
 0.80A 6iblB-4gbrA:
32.7		 6iblB-4gbrA:
50.65
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6MXT_A_K5YA1401_0
(ENDOLYSIN, BETA-2
ADRENERGIC RECEPTOR
CHIMERA)		 4gbr BETA-2 ADRENERGIC
RECEPTOR
(Homo
sapiens) 		6 / 12 ASP A 192
HIS A 268
TYR A 280
ILE A 281
ASN A 284
TYR A 288
 None
None
None
None
CAU  A 500 (-3.3A)
CAU  A 500 (-4.6A)
 1.33A 6mxtA-4gbrA:
34.3		 6mxtA-4gbrA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6MXT_A_K5YA1401_0
(ENDOLYSIN, BETA-2
ADRENERGIC RECEPTOR
CHIMERA)		 4gbr BETA-2 ADRENERGIC
RECEPTOR
(Homo
sapiens) 		7 / 12 TRP A 109
ASP A 192
PHE A 261
ASN A 265
TYR A 280
ILE A 281
TYR A 288
 None
None
CAU  A 500 (-4.2A)
CAU  A 500 (-3.4A)
None
None
CAU  A 500 (-4.6A)
 0.87A 6mxtA-4gbrA:
34.3		 6mxtA-4gbrA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6MXT_A_K5YA1401_0
(ENDOLYSIN, BETA-2
ADRENERGIC RECEPTOR
CHIMERA)		 4gbr BETA-2 ADRENERGIC
RECEPTOR
(Homo
sapiens) 		7 / 12 TRP A 109
ASP A 192
PHE A 261
TYR A 280
ILE A 281
ASN A 284
TYR A 288
 None
None
CAU  A 500 (-4.2A)
None
None
CAU  A 500 (-3.3A)
CAU  A 500 (-4.6A)
 0.79A 6mxtA-4gbrA:
34.3		 6mxtA-4gbrA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6MXT_A_K5YA1401_0
(ENDOLYSIN, BETA-2
ADRENERGIC RECEPTOR
CHIMERA)		 4gbr BETA-2 ADRENERGIC
RECEPTOR
(Homo
sapiens) 		8 / 12 TRP A 109
VAL A 114
ASP A 192
PHE A 193
PHE A 261
TYR A 280
ASN A 284
TYR A 288
 None
CAU  A 500 (-3.5A)
None
CAU  A 500 (-4.5A)
CAU  A 500 (-4.2A)
None
CAU  A 500 (-3.3A)
CAU  A 500 (-4.6A)
 0.74A 6mxtA-4gbrA:
34.3		 6mxtA-4gbrA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6MXT_A_K5YA1401_0
(ENDOLYSIN, BETA-2
ADRENERGIC RECEPTOR
CHIMERA)		 4gbr BETA-2 ADRENERGIC
RECEPTOR
(Homo
sapiens) 		9 / 12 TRP A 109
VAL A 114
VAL A 117
ASP A 192
PHE A 193
PHE A 261
ASN A 265
TYR A 280
TYR A 288
 None
CAU  A 500 (-3.5A)
CAU  A 500 (-4.2A)
None
CAU  A 500 (-4.5A)
CAU  A 500 (-4.2A)
CAU  A 500 (-3.4A)
None
CAU  A 500 (-4.6A)
 0.78A 6mxtA-4gbrA:
34.3		 6mxtA-4gbrA:
100.00