SIMILAR PATTERN OF AMINO ACIDS MAPPED TO 'CAS'

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)	View	Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2J5M_A_ACTA1321_0 (CHLOROPEROXIDASE)	2w9j	SIGNAL RECOGNITION PARTICLE SUBUNIT SRP14 (Schizosaccharomy ces pombe)	4 / 6	LEU A  12 PHE A  70 ILE A  48 ALA A  50	None None CAS  A  33 ( 4.1A) None	0.85A	2j5mA-2w9jA: undetectable	2j5mA-2w9jA: 13.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2O4N_A_TPVA300_2 (PROTEASE)	2jbh	PHOSPHORIBOSYLTRANSF ERASE DOMAIN-CONTAINING PROTEIN 1 (Homo sapiens)	5 / 8	LEU A  56 ILE A  92 GLY A  65 ILE A  64 LEU A  85	None None None None CAS  A  82 ( 4.5A)	1.15A	2o4nB-2jbhA: undetectable	2o4nB-2jbhA: 18.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2X0P_A_ADNA1607_1 (ALCALIGIN BIOSYNTHESIS PROTEIN)	1fu1	DNA REPAIR PROTEIN XRCC4 (Homo sapiens)	4 / 8	GLY A  39 HIS A  40 ILE A 127 ALA A  42	None None CAS  A 128 ( 3.9A) None	0.91A	2x0pA-1fu1A: 2.1	2x0pA-1fu1A: 15.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3HEC_A_STIA1_1 (MITOGEN-ACTIVATED PROTEIN KINASE 14)	5dbx	STE20/SPS1-RELATED PROLINE-ALANINE-RICH PROTEIN KINASE (Mus musculus)	5 / 12	ALA A 352 LYS A 347 LEU A 328 LEU A 325 LEU A 344	None CAS  A 346 ( 2.8A) None CAS  A 346 ( 4.8A) None	1.03A	3hecA-5dbxA: 19.2	3hecA-5dbxA: 26.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3O14_A_NIOA300_1 (ANTI-ECFSIGMA FACTOR, CHRR)	3g2f	BONE MORPHOGENETIC PROTEIN RECEPTOR TYPE-2 (Homo sapiens)	4 / 7	ALA A 400 VAL A 387 VAL A 404 LEU A 401	EDO  A   5 (-3.4A) None None CAS  A 397 ( 3.6A)	0.83A	3o14A-3g2fA: undetectable	3o14A-3g2fA: 23.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3OZK_A_T44A128_1 (TRANSTHYRETIN)	4wp2	PUTATIVE MRNA EXPORT PROTEIN (Chaetomium thermophilum)	5 / 9	MET A 615 LEU A 624 THR A 613 LEU A 605 VAL A 657	CAS  A 623 ( 3.6A) CAS  A 623 ( 4.2A) None None None	1.39A	3ozkA-4wp2A: undetectable	3ozkA-4wp2A: 16.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3WIP_G_ACTG305_0 (ACETYLCHOLINE-BINDIN G PROTEIN)	1fu1	DNA REPAIR PROTEIN XRCC4 (Homo sapiens)	3 / 3	ASP A 132 ARG A   3 LYS A 129	CAS  A 128 ( 3.1A) ACY  A 504 (-2.8A) CAS  A 130 ( 1.3A)	1.18A	3wipG-1fu1A: 0.0	3wipG-1fu1A: 22.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4M2V_A_BZ1A302_1 (CARBONIC ANHYDRASE 2)	2jbh	PHOSPHORIBOSYLTRANSF ERASE DOMAIN-CONTAINING PROTEIN 1 (Homo sapiens)	5 / 12	LEU A 138 VAL A  71 GLY A  65 VAL A 100 VAL A 104	None None None None CAS  A  82 ( 4.2A)	0.82A	4m2vA-2jbhA: undetectable	4m2vA-2jbhA: 21.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4OR0_A_NPSA602_1 (SERUM ALBUMIN)	2jbh	PHOSPHORIBOSYLTRANSF ERASE DOMAIN-CONTAINING PROTEIN 1 (Homo sapiens)	5 / 9	PHE A  81 ALA A 199 SER A 169 LEU A 170 VAL A 143	CAS  A  82 ( 4.7A) None None None 5GP  A1230 (-4.0A)	1.11A	4or0A-2jbhA: undetectable	4or0A-2jbhA: 16.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4USW_A_ACTA1470_0 (ADENYLATE CYCLASE TYPE 10)	2cjw	GTP-BINDING PROTEIN GEM (Homo sapiens)	4 / 6	LYS A 210 LEU A 188 ARG A 176 PHE A 213	CAS  A 209 ( 3.0A) CAS  A 215 ( 4.5A) CAS  A 215 ( 4.4A) CAS  A 209 (-4.6A)	1.02A	4uswA-2cjwA: undetectable	4uswA-2cjwA: 19.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5KI6_A_IPHA901_0 (PROTEIN ARGONAUTE-2)	5bo4	SUPPRESSOR OF CYTOKINE SIGNALING 2 (Homo sapiens)	4 / 5	LEU A 106 LYS A 117 LEU A 125 TYR A 129	CAS  A 111 ( 4.4A) None None None	1.43A	5ki6A-5bo4A: undetectable	5ki6A-5bo4A: 12.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6EXI_C_ADNC502_1 (ADENOSYLHOMOCYSTEINA SE)	3g2f	BONE MORPHOGENETIC PROTEIN RECEPTOR TYPE-2 (Homo sapiens)	3 / 3	LEU A 492 GLY A 410 PHE A 462	CAS  A 496 ( 4.4A) None None	0.63A	6exiC-3g2fA: undetectable	6exiC-3g2fA: 12.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6HLP_A_GAWA1501_0 (SUBSTANCE-P RECEPTOR,SUBSTANCE-P RECEPTOR)	4b09	TRANSCRIPTIONAL REGULATORY PROTEIN BAER (Escherichia coli)	5 / 12	PRO A  83 ILE A  82 ILE A  84 VAL A  50 ILE A  76	None None CAS  A  73 ( 4.3A) None CAS  A  73 ( 4.3A)	1.15A	6hlpA-4b09A: 4.5	6hlpA-4b09A: 19.07