SIMILAR PATTERN OF AMINO ACIDS MAPPED TO 'CAP'


List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AM6_A_HAEA555_1
(CARBONIC ANHYDRASE)		 5hql RIBULOSE
BISPHOSPHATE
CARBOXYLASE
(Rhodopseudomonas
palustris) 		4 / 7 HIS A 286
HIS A 322
HIS A 288
THR A 392
 KCX  A 192 ( 3.5A)
KCX  A 192 (-3.8A)
CAP  A 500 (-3.9A)
KCX  A 192 ( 3.1A)
 0.91A 1am6A-5hqlA:
undetectable		 1am6A-5hqlA:
18.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AM6_A_HAEA555_1
(CARBONIC ANHYDRASE)		 5mac RIBULOSE-1,5-BISPHOS
PHATE
CARBOXYLASE-OXYGENAS
E TYPE III
(Methanococcoides
burtonii) 		4 / 7 HIS A 286
HIS A 322
HIS A 288
THR A 422
 KCX  A 193 ( 4.3A)
CAP  A 501 (-4.0A)
CAP  A 501 (-3.8A)
KCX  A 193 ( 3.7A)
 0.80A 1am6A-5macA:
undetectable		 1am6A-5macA:
20.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HRK_A_CHDA1502_0
(FERROCHELATASE)		 5nv3 RIBULOSE
BISPHOSPHATE
CARBOXYLASE LARGE
CHAIN
(Rhodobacter
sphaeroides) 		4 / 8 MET A 388
LEU A 199
GLY A 405
TRP A 463
 None
None
CAP  A1001 (-3.7A)
None
 1.01A 1hrkA-5nv3A:
undetectable		 1hrkA-5nv3A:
21.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HRK_B_CHDB2502_0
(FERROCHELATASE)		 5nv3 RIBULOSE
BISPHOSPHATE
CARBOXYLASE LARGE
CHAIN
(Rhodobacter
sphaeroides) 		4 / 8 MET A 388
LEU A 199
GLY A 405
TRP A 463
 None
None
CAP  A1001 (-3.7A)
None
 1.01A 1hrkB-5nv3A:
undetectable		 1hrkB-5nv3A:
21.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JG3_A_ADNA500_1
(PROTEIN-L-ISOASPARTA
TE
O-METHYLTRANSFERASE)		 6ftl RIBULOSE
BISPHOSPHATE
CARBOXYLASE LARGE
CHAIN
(Skeletonema
marinoi) 		5 / 11 GLY A 336
GLY A 384
ILE A 470
ASP A 473
THR A 333
 None
CAP  A 501 (-4.1A)
None
None
None
 1.07A 1jg3A-6ftlA:
undetectable		 1jg3A-6ftlA:
16.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JG3_B_ADNB550_1
(PROTEIN-L-ISOASPARTA
TE
O-METHYLTRANSFERASE)		 6ftl RIBULOSE
BISPHOSPHATE
CARBOXYLASE LARGE
CHAIN
(Skeletonema
marinoi) 		5 / 11 GLY A 336
GLY A 384
ILE A 470
ASP A 473
THR A 333
 None
CAP  A 501 (-4.1A)
None
None
None
 1.08A 1jg3B-6ftlA:
undetectable		 1jg3B-6ftlA:
16.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WG8_A_SAMA3142_0
(PREDICTED
S-ADENOSYLMETHIONINE
-DEPENDENT
METHYLTRANSFERASE)		 5hql RIBULOSE
BISPHOSPHATE
CARBOXYLASE
(Rhodopseudomonas
palustris) 		5 / 12 THR A 392
GLY A 394
GLY A 395
GLY A 371
PHE A 190
 KCX  A 192 ( 3.1A)
CAP  A 500 (-3.4A)
CAP  A 500 (-3.7A)
CAP  A 500 (-3.4A)
KCX  A 192 ( 4.0A)
 0.85A 1wg8A-5hqlA:
undetectable		 1wg8A-5hqlA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WG8_B_SAMB3141_0
(PREDICTED
S-ADENOSYLMETHIONINE
-DEPENDENT
METHYLTRANSFERASE)		 5hql RIBULOSE
BISPHOSPHATE
CARBOXYLASE
(Rhodopseudomonas
palustris) 		5 / 12 THR A 392
GLY A 394
GLY A 395
GLY A 371
PHE A 190
 KCX  A 192 ( 3.1A)
CAP  A 500 (-3.4A)
CAP  A 500 (-3.7A)
CAP  A 500 (-3.4A)
KCX  A 192 ( 4.0A)
 0.85A 1wg8B-5hqlA:
undetectable		 1wg8B-5hqlA:
22.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F16_N_BO2N1404_1
(PROTEASOME COMPONENT
PRE3)		 3kdn RIBULOSE
BISPHOSPHATE
CARBOXYLASE
(Thermococcus
kodakarensis) 		5 / 11 THR A 317
ALA A 318
ARG A 338
ALA A 334
SER A 367
 None
None
None
None
CAP  A 600 (-2.5A)
 1.22A 2f16N-3kdnA:
undetectable		 2f16N-3kdnA:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2UXP_B_CLMB1211_0
(HTH-TYPE
TRANSCRIPTIONAL
REGULATOR TTGR)		 5mac RIBULOSE-1,5-BISPHOS
PHATE
CARBOXYLASE-OXYGENAS
E TYPE III
(Methanococcoides
burtonii) 		5 / 11 HIS A 322
ALA A 313
VAL A 306
GLY A 265
ILE A 266
 CAP  A 501 (-4.0A)
None
None
None
None
 1.25A 2uxpB-5macA:
undetectable		 2uxpB-5macA:
17.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V0M_A_KLNA1501_1
(CYTOCHROME P450 3A4)		 5hql RIBULOSE
BISPHOSPHATE
CARBOXYLASE
(Rhodopseudomonas
palustris) 		5 / 10 ASP A 194
SER A 310
ILE A 321
ILE A 340
GLY A 370
 MG  A 501 ( 2.9A)
None
None
None
CAP  A 500 (-3.0A)
 1.28A 2v0mA-5hqlA:
undetectable		 2v0mA-5hqlA:
21.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZWE_B_DAHB98_1
(TYROSINASE
MELC)		 5mac RIBULOSE-1,5-BISPHOS
PHATE
CARBOXYLASE-OXYGENAS
E TYPE III
(Methanococcoides
burtonii) 		5 / 11 HIS A 322
ILE A 397
HIS A 286
SER A 399
ASP A 190
 CAP  A 501 (-4.0A)
None
KCX  A 193 ( 4.3A)
CAP  A 501 (-3.2A)
None
 1.26A 2zweA-5macA:
undetectable
2zweB-5macA:
undetectable		 2zweA-5macA:
21.47
2zweB-5macA:
14.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HS4_A_AZMA701_1
(CARBONIC ANHYDRASE 2)		 5hql RIBULOSE
BISPHOSPHATE
CARBOXYLASE
(Rhodopseudomonas
palustris) 		5 / 11 HIS A 286
HIS A 322
HIS A 288
PHE A 229
THR A 392
 KCX  A 192 ( 3.5A)
KCX  A 192 (-3.8A)
CAP  A 500 (-3.9A)
KCX  A 192 ( 4.3A)
KCX  A 192 ( 3.1A)
 1.10A 3hs4A-5hqlA:
undetectable		 3hs4A-5hqlA:
18.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JZJ_A_ACRA405_1
(ACARBOSE/MALTOSE
BINDING PROTEIN GACH)		 3kdn RIBULOSE
BISPHOSPHATE
CARBOXYLASE
(Thermococcus
kodakarensis) 		5 / 12 GLU A 192
GLY A 392
ALA A 320
GLY A 316
ASN A 374
 MG  A 500 ( 2.5A)
CAP  A 600 (-3.8A)
None
None
None
 1.22A 3jzjA-3kdnA:
undetectable		 3jzjA-3kdnA:
22.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SI7_A_ACTA5_0
(CYSTIC FIBROSIS
TRANSMEMBRANE
CONDUCTANCE
REGULATOR)		 3kdn RIBULOSE
BISPHOSPHATE
CARBOXYLASE
(Thermococcus
kodakarensis) 		3 / 3 LYS A 163
SER A 367
GLN A 389
 CAP  A 600 (-3.0A)
CAP  A 600 (-2.5A)
CAP  A 600 (-3.4A)
 0.79A 3si7A-3kdnA:
undetectable		 3si7A-3kdnA:
21.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SI7_C_ACTC4_0
(CYSTIC FIBROSIS
TRANSMEMBRANE
CONDUCTANCE
REGULATOR)		 5nv3 RIBULOSE
BISPHOSPHATE
CARBOXYLASE LARGE
CHAIN
(Rhodobacter
sphaeroides) 		4 / 4 GLY A 382
GLY A 334
THR A 331
LEU A 391
 CAP  A1001 (-3.8A)
None
None
None
 0.81A 3si7C-5nv3A:
undetectable
3si7D-5nv3A:
undetectable		 3si7C-5nv3A:
19.36
3si7D-5nv3A:
19.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V2M_A_AZMA303_1
(CARBONIC ANHYDRASE 2)		 5hql RIBULOSE
BISPHOSPHATE
CARBOXYLASE
(Rhodopseudomonas
palustris) 		5 / 10 HIS A 286
HIS A 322
HIS A 288
PHE A 229
THR A 392
 KCX  A 192 ( 3.5A)
KCX  A 192 (-3.8A)
CAP  A 500 (-3.9A)
KCX  A 192 ( 4.3A)
KCX  A 192 ( 3.1A)
 1.11A 3v2mA-5hqlA:
undetectable		 3v2mA-5hqlA:
18.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRI_A_CAMA502_0
(CAMPHOR
5-MONOOXYGENASE)		 3kdn RIBULOSE
BISPHOSPHATE
CARBOXYLASE
(Thermococcus
kodakarensis) 		4 / 5 GLY A 368
THR A 317
ILE A 375
VAL A 378
 CAP  A 600 (-3.3A)
None
None
None
 0.89A 3wriA-3kdnA:
undetectable		 3wriA-3kdnA:
21.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRI_B_CAMB502_0
(CAMPHOR
5-MONOOXYGENASE)		 3kdn RIBULOSE
BISPHOSPHATE
CARBOXYLASE
(Thermococcus
kodakarensis) 		4 / 5 GLY A 368
THR A 317
ILE A 375
VAL A 378
 CAP  A 600 (-3.3A)
None
None
None
 0.89A 3wriB-3kdnA:
undetectable		 3wriB-3kdnA:
21.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N16_A_CHDA301_0
(CARBONIC ANHYDRASE 2)		 5hql RIBULOSE
BISPHOSPHATE
CARBOXYLASE
(Rhodopseudomonas
palustris) 		4 / 8 HIS A 286
HIS A 322
HIS A 288
THR A 392
 KCX  A 192 ( 3.5A)
KCX  A 192 (-3.8A)
CAP  A 500 (-3.9A)
KCX  A 192 ( 3.1A)
 0.91A 4n16A-5hqlA:
undetectable		 4n16A-5hqlA:
18.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N16_A_CHDA301_0
(CARBONIC ANHYDRASE 2)		 5mac RIBULOSE-1,5-BISPHOS
PHATE
CARBOXYLASE-OXYGENAS
E TYPE III
(Methanococcoides
burtonii) 		4 / 8 HIS A 286
HIS A 322
HIS A 288
THR A 422
 KCX  A 193 ( 4.3A)
CAP  A 501 (-4.0A)
CAP  A 501 (-3.8A)
KCX  A 193 ( 3.7A)
 0.81A 4n16A-5macA:
undetectable		 4n16A-5macA:
19.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OLT_A_GCSA303_1
(CHITOSANASE)		 5hql RIBULOSE
BISPHOSPHATE
CARBOXYLASE
(Rhodopseudomonas
palustris) 		4 / 6 ILE A 165
ASP A 194
GLY A 370
HIS A 288
 KCX  A 192 (-3.7A)
MG  A 501 ( 2.9A)
CAP  A 500 (-3.0A)
CAP  A 500 (-3.9A)
 0.88A 4oltA-5hqlA:
undetectable		 4oltA-5hqlA:
22.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OLT_A_GCSA303_1
(CHITOSANASE)		 5mac RIBULOSE-1,5-BISPHOS
PHATE
CARBOXYLASE-OXYGENAS
E TYPE III
(Methanococcoides
burtonii) 		4 / 6 ILE A 165
ASP A 195
GLY A 400
HIS A 288
 CAP  A 501 (-3.7A)
MG  A 502 ( 3.0A)
CAP  A 501 (-3.0A)
CAP  A 501 (-3.8A)
 0.87A 4oltA-5macA:
undetectable		 4oltA-5macA:
19.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OLT_B_GCSB303_1
(CHITOSANASE)		 5hql RIBULOSE
BISPHOSPHATE
CARBOXYLASE
(Rhodopseudomonas
palustris) 		4 / 6 ILE A 165
ASP A 194
GLY A 370
HIS A 288
 KCX  A 192 (-3.7A)
MG  A 501 ( 2.9A)
CAP  A 500 (-3.0A)
CAP  A 500 (-3.9A)
 0.87A 4oltB-5hqlA:
undetectable		 4oltB-5hqlA:
22.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OLT_B_GCSB303_1
(CHITOSANASE)		 5mac RIBULOSE-1,5-BISPHOS
PHATE
CARBOXYLASE-OXYGENAS
E TYPE III
(Methanococcoides
burtonii) 		4 / 6 ILE A 165
ASP A 195
GLY A 400
HIS A 288
 CAP  A 501 (-3.7A)
MG  A 502 ( 3.0A)
CAP  A 501 (-3.0A)
CAP  A 501 (-3.8A)
 0.87A 4oltB-5macA:
undetectable		 4oltB-5macA:
19.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RP8_C_ASCC501_0
(ASCORBATE-SPECIFIC
PERMEASE IIC
COMPONENT ULAA)		 5mac RIBULOSE-1,5-BISPHOS
PHATE
CARBOXYLASE-OXYGENAS
E TYPE III
(Methanococcoides
burtonii) 		5 / 12 LEU A 262
THR A 422
ILE A 397
HIS A 322
ILE A 165
 None
KCX  A 193 ( 3.7A)
None
CAP  A 501 (-4.0A)
CAP  A 501 (-3.7A)
 1.19A 4rp8C-5macA:
undetectable		 4rp8C-5macA:
23.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ESG_A_1YNA701_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 5nv3 RIBULOSE
BISPHOSPHATE
CARBOXYLASE LARGE
CHAIN
(Rhodobacter
sphaeroides) 		5 / 12 ILE A 115
TYR A 275
GLY A 323
LEU A 327
HIS A 328
 None
None
None
None
CAP  A1001 (-4.0A)
 1.39A 5esgA-5nv3A:
undetectable		 5esgA-5nv3A:
22.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0R_A_SAMA501_0
(PEPTIDE
N-METHYLTRANSFERASE)		 3kdn RIBULOSE
BISPHOSPHATE
CARBOXYLASE
(Thermococcus
kodakarensis) 		5 / 12 ILE A 278
GLY A 280
HIS A 281
VAL A 257
ALA A 271
 None
None
CAP  A 600 (-4.1A)
None
None
 1.03A 5n0rA-3kdnA:
undetectable		 5n0rA-3kdnA:
23.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0T_A_SAMA501_0
(PEPTIDE
N-METHYLTRANSFERASE)		 3kdn RIBULOSE
BISPHOSPHATE
CARBOXYLASE
(Thermococcus
kodakarensis) 		5 / 12 ILE A 278
GLY A 280
HIS A 281
VAL A 257
ALA A 271
 None
None
CAP  A 600 (-4.1A)
None
None
 1.04A 5n0tA-3kdnA:
undetectable		 5n0tA-3kdnA:
23.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0T_B_SAMB501_0
(PEPTIDE
N-METHYLTRANSFERASE)		 3kdn RIBULOSE
BISPHOSPHATE
CARBOXYLASE
(Thermococcus
kodakarensis) 		5 / 12 ILE A 278
GLY A 280
HIS A 281
VAL A 257
ALA A 271
 None
None
CAP  A 600 (-4.1A)
None
None
 1.06A 5n0tB-3kdnA:
undetectable		 5n0tB-3kdnA:
23.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5O96_A_SAMA501_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE E)		 1rbl RIBULOSE 1,5
BISPHOSPHATE
CARBOXYLASE/OXYGENAS
E (LARGE CHAIN)
(Synechococcus
elongatus) 		5 / 11 LEU A 326
GLY A 329
LEU A 318
ARG A 312
ALA A 315
 None
CAP  A 476 ( 4.3A)
None
None
None
 1.13A 5o96A-1rblA:
undetectable
5o96B-1rblA:
3.5		 5o96A-1rblA:
20.44
5o96B-1rblA:
20.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5V5Z_A_1YNA602_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 5nv3 RIBULOSE
BISPHOSPHATE
CARBOXYLASE LARGE
CHAIN
(Rhodobacter
sphaeroides) 		5 / 12 ILE A 115
TYR A 275
GLY A 323
LEU A 327
HIS A 328
 None
None
None
None
CAP  A1001 (-4.0A)
 1.41A 5v5zA-5nv3A:
undetectable		 5v5zA-5nv3A:
22.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y2T_B_8LXB501_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 6ftl RIBULOSE
BISPHOSPHATE
CARBOXYLASE LARGE
CHAIN
(Skeletonema
marinoi) 		4 / 8 GLU A 208
HIS A 330
PHE A 203
LEU A 166
 MG  A 500 ( 2.7A)
CAP  A 501 (-3.8A)
None
None
 1.08A 5y2tB-6ftlA:
undetectable		 5y2tB-6ftlA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z0F_B_DAHB98_0
(MELC
TYROSINASE)		 5hql RIBULOSE
BISPHOSPHATE
CARBOXYLASE
(Rhodopseudomonas
palustris) 		5 / 11 HIS A 322
ILE A 367
HIS A 286
SER A 369
ASP A 189
 KCX  A 192 (-3.8A)
None
KCX  A 192 ( 3.5A)
CAP  A 500 (-3.3A)
None
 1.24A 5z0fA-5hqlA:
undetectable
5z0fB-5hqlA:
undetectable		 5z0fA-5hqlA:
9.98
5z0fB-5hqlA:
10.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZOV_A_ASCA501_0
(PTS
ASCORBATE-SPECIFIC
SUBUNIT IIBC)		 5mac RIBULOSE-1,5-BISPHOS
PHATE
CARBOXYLASE-OXYGENAS
E TYPE III
(Methanococcoides
burtonii) 		5 / 10 HIS A 286
ILE A 397
HIS A 322
ALA A 290
ILE A 165
 KCX  A 193 ( 4.3A)
None
CAP  A 501 (-4.0A)
None
CAP  A 501 (-3.7A)
 1.20A 5zovA-5macA:
undetectable		 5zovA-5macA:
24.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZOV_B_ASCB501_0
(PTS
ASCORBATE-SPECIFIC
SUBUNIT IIBC)		 5mac RIBULOSE-1,5-BISPHOS
PHATE
CARBOXYLASE-OXYGENAS
E TYPE III
(Methanococcoides
burtonii) 		5 / 12 HIS A 286
ILE A 397
HIS A 322
ALA A 290
ILE A 165
 KCX  A 193 ( 4.3A)
None
CAP  A 501 (-4.0A)
None
CAP  A 501 (-3.7A)
 1.20A 5zovB-5macA:
undetectable		 5zovB-5macA:
24.82