SIMILAR PATTERN OF AMINO ACIDS MAPPED TO 'CAJ'


List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_C_FUAC701_1
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 4emw COENZYME A DISULFIDE
REDUCTASE
(Staphylococcus
aureus) 		4 / 4 ALA A 301
VAL A 305
ALA A 302
HIS A 299
 None
None
None
CAJ  A 503 (-4.1A)
 1.03A 1q23A-4emwA:
undetectable		 1q23A-4emwA:
19.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_J_FUAJ711_2
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 4emw COENZYME A DISULFIDE
REDUCTASE
(Staphylococcus
aureus) 		4 / 4 ALA A 301
VAL A 305
ALA A 302
HIS A 299
 None
None
None
CAJ  A 503 (-4.1A)
 1.05A 1q23K-4emwA:
undetectable		 1q23K-4emwA:
19.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXC_A_P1ZA2001_1
(SERUM ALBUMIN)		 4emw COENZYME A DISULFIDE
REDUCTASE
(Staphylococcus
aureus) 		5 / 12 SER A  39
ALA A 306
ILE A 309
ILE A  20
ALA A  17
 CAJ  A 503 (-3.0A)
None
None
None
None
 0.99A 2bxcA-4emwA:
undetectable		 2bxcA-4emwA:
20.47