SIMILAR PATTERN OF AMINO ACIDS MAPPED TO 'C7V'


List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1M8E_B_H4BB903_1
(INDUCIBLE NITRIC
OXIDE SYNTHASE)		 6b0t FASCIN
(Homo
sapiens) 		3 / 3 ARG A 224
ILE A  93
TRP A 101
 None
C7V  A 501 ( 4.2A)
C7V  A 501 (-3.2A)
 1.14A 1m8eB-6b0tA:
undetectable		 1m8eB-6b0tA:
13.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NOD_B_H4BB902_1
(NITRIC OXIDE
SYNTHASE)		 6b0t FASCIN
(Homo
sapiens) 		3 / 3 ARG A 224
ILE A  93
TRP A 101
 None
C7V  A 501 ( 4.2A)
C7V  A 501 (-3.2A)
 1.14A 1nodB-6b0tA:
undetectable		 1nodB-6b0tA:
13.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2KCE_B_D16B568_1
(THYMIDYLATE SYNTHASE)		 6b0t FASCIN
(Homo
sapiens) 		5 / 12 SER A  36
LEU A  62
GLY A 113
VAL A  78
ALA A  72
 None
C7V  A 501 (-4.5A)
None
None
None
 1.15A 2kceB-6b0tA:
undetectable		 2kceB-6b0tA:
14.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NOD_B_H4BB902_1
(NITRIC OXIDE
SYNTHASE)		 6b0t FASCIN
(Homo
sapiens) 		3 / 3 ARG A 224
ILE A  93
TRP A 101
 None
C7V  A 501 ( 4.2A)
C7V  A 501 (-3.2A)
 1.15A 2nodB-6b0tA:
undetectable		 2nodB-6b0tA:
13.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3E68_A_H4BA902_1
(NITRIC OXIDE
SYNTHASE, INDUCIBLE)		 6b0t FASCIN
(Homo
sapiens) 		3 / 3 ARG A 224
ILE A  93
TRP A 101
 None
C7V  A 501 ( 4.2A)
C7V  A 501 (-3.2A)
 1.10A 3e68A-6b0tA:
undetectable		 3e68A-6b0tA:
13.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3E6T_B_H4BB902_1
(NITRIC OXIDE
SYNTHASE, INDUCIBLE)		 6b0t FASCIN
(Homo
sapiens) 		3 / 3 ARG A 224
ILE A  93
TRP A 101
 None
C7V  A 501 ( 4.2A)
C7V  A 501 (-3.2A)
 1.13A 3e6tB-6b0tA:
undetectable		 3e6tB-6b0tA:
13.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KIR_A_RCXA601_2
(PROSTAGLANDIN G/H
SYNTHASE 2)		 6b0t FASCIN
(Homo
sapiens) 		3 / 3 ARG A 217
ILE A  12
PHE A 216
 C7V  A 501 (-3.8A)
None
C7V  A 501 (-3.2A)
 0.66A 5kirA-6b0tA:
undetectable		 5kirA-6b0tA:
10.99