SIMILAR PATTERN OF AMINO ACIDS MAPPED TO 'C6M'


List of Similar Pattern of Amino Acids


Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RQJ_A_RISA901_1
(GERANYLTRANSTRANSFER
ASE)
6b07 FARNESYL DIPHOSPHATE
SYNTHASE

(Choristoneura
fumiferana)
9 / 11 ASP A 147
ASP A 151
ARG A 156
GLN A 215
LYS A 244
THR A 245
GLN A 284
ASP A 287
LYS A 301
MG  A 402 (-2.6A)
MG  A 402 (-2.5A)
C6M  A 401 (-2.7A)
C6M  A 401 (-3.3A)
C6M  A 401 (-2.6A)
C6M  A 401 (-3.6A)
C6M  A 401 (-3.7A)
MG  A 404 ( 2.7A)
C6M  A 401 (-2.9A)
0.40A 1rqjA-6b07A:
29.5
1rqjA-6b07A:
13.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RQJ_B_RISB903_1
(GERANYLTRANSTRANSFER
ASE)
6b07 FARNESYL DIPHOSPHATE
SYNTHASE

(Choristoneura
fumiferana)
9 / 11 ASP A 147
ASP A 151
ARG A 156
GLN A 215
LYS A 244
THR A 245
GLN A 284
ASP A 287
LYS A 301
MG  A 402 (-2.6A)
MG  A 402 (-2.5A)
C6M  A 401 (-2.7A)
C6M  A 401 (-3.3A)
C6M  A 401 (-2.6A)
C6M  A 401 (-3.6A)
C6M  A 401 (-3.7A)
MG  A 404 ( 2.7A)
C6M  A 401 (-2.9A)
0.42A 1rqjB-6b07A:
29.6
1rqjB-6b07A:
13.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T03_P_TFOP822_1
(POL POLYPROTEIN
SYNTHETIC
OLIGONUCLEOTIDE
PRIMER)
6b07 FARNESYL DIPHOSPHATE
SYNTHASE

(Choristoneura
fumiferana)
4 / 7 MET A 150
ASP A 151
ASP A 148
LYS A 301
None
MG  A 402 (-2.5A)
None
C6M  A 401 (-2.9A)
1.17A 1t03A-6b07A:
undetectable
1t03A-6b07A:
11.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YHL_A_RISA1400_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)
6b07 FARNESYL DIPHOSPHATE
SYNTHASE

(Choristoneura
fumiferana)
10 / 11 ASP A 147
ASP A 151
ARG A 156
GLN A 215
LYS A 244
THR A 245
TYR A 248
GLN A 284
ASP A 287
LYS A 301
MG  A 402 (-2.6A)
MG  A 402 (-2.5A)
C6M  A 401 (-2.7A)
C6M  A 401 (-3.3A)
C6M  A 401 (-2.6A)
C6M  A 401 (-3.6A)
None
C6M  A 401 (-3.7A)
MG  A 404 ( 2.7A)
C6M  A 401 (-2.9A)
0.42A 1yhlA-6b07A:
43.9
1yhlA-6b07A:
12.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YQ7_A_RISA901_1
(FARNESYL
PYROPHOSPHATE
SYNTHETASE)
6b07 FARNESYL DIPHOSPHATE
SYNTHASE

(Choristoneura
fumiferana)
10 / 11 ASP A 147
ASP A 151
ARG A 156
GLN A 215
LYS A 244
THR A 245
TYR A 248
GLN A 284
ASP A 287
LYS A 301
MG  A 402 (-2.6A)
MG  A 402 (-2.5A)
C6M  A 401 (-2.7A)
C6M  A 401 (-3.3A)
C6M  A 401 (-2.6A)
C6M  A 401 (-3.6A)
None
C6M  A 401 (-3.7A)
MG  A 404 ( 2.7A)
C6M  A 401 (-2.9A)
0.32A 1yq7A-6b07A:
46.2
1yq7A-6b07A:
14.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YV5_A_RISA901_1
(FARNESYL
PYROPHOSPHATE
SYNTHETASE)
6b07 FARNESYL DIPHOSPHATE
SYNTHASE

(Choristoneura
fumiferana)
9 / 10 ASP A 147
ASP A 151
ARG A 156
GLN A 215
LYS A 244
THR A 245
GLN A 284
ASP A 287
LYS A 301
MG  A 402 (-2.6A)
MG  A 402 (-2.5A)
C6M  A 401 (-2.7A)
C6M  A 401 (-3.3A)
C6M  A 401 (-2.6A)
C6M  A 401 (-3.6A)
C6M  A 401 (-3.7A)
MG  A 404 ( 2.7A)
C6M  A 401 (-2.9A)
0.37A 1yv5A-6b07A:
46.6
1yv5A-6b07A:
14.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZW5_A_ZOLA901_1
(FARNESYL DIPHOSPHATE
SYNTHASE)
6b07 FARNESYL DIPHOSPHATE
SYNTHASE

(Choristoneura
fumiferana)
9 / 9 ASP A 147
ASP A 151
ARG A 156
GLN A 215
LYS A 244
THR A 245
GLN A 284
ASP A 287
LYS A 301
MG  A 402 (-2.6A)
MG  A 402 (-2.5A)
C6M  A 401 (-2.7A)
C6M  A 401 (-3.3A)
C6M  A 401 (-2.6A)
C6M  A 401 (-3.6A)
C6M  A 401 (-3.7A)
MG  A 404 ( 2.7A)
C6M  A 401 (-2.9A)
0.44A 1zw5A-6b07A:
47.4
1zw5A-6b07A:
14.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2E91_A_ZOLA901_1
(GERANYLGERANYL
PYROPHOSPHATE
SYNTHETASE)
6b07 FARNESYL DIPHOSPHATE
SYNTHASE

(Choristoneura
fumiferana)
8 / 9 ASP A 147
ASP A 151
ARG A 156
GLN A 215
LYS A 244
THR A 245
GLN A 284
ASP A 287
MG  A 402 (-2.6A)
MG  A 402 (-2.5A)
C6M  A 401 (-2.7A)
C6M  A 401 (-3.3A)
C6M  A 401 (-2.6A)
C6M  A 401 (-3.6A)
C6M  A 401 (-3.7A)
MG  A 404 ( 2.7A)
0.36A 2e91A-6b07A:
25.2
2e91A-6b07A:
14.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2E91_A_ZOLA901_1
(GERANYLGERANYL
PYROPHOSPHATE
SYNTHETASE)
6b07 FARNESYL DIPHOSPHATE
SYNTHASE

(Choristoneura
fumiferana)
5 / 9 ASP A 147
ASP A 151
GLN A 215
LYS A 244
LYS A 310
MG  A 402 (-2.6A)
MG  A 402 (-2.5A)
C6M  A 401 (-3.3A)
C6M  A 401 (-2.6A)
MG  A 402 ( 4.3A)
1.48A 2e91A-6b07A:
25.2
2e91A-6b07A:
14.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2E91_B_ZOLB902_1
(GERANYLGERANYL
PYROPHOSPHATE
SYNTHETASE)
6b07 FARNESYL DIPHOSPHATE
SYNTHASE

(Choristoneura
fumiferana)
8 / 9 ASP A 147
ASP A 151
ARG A 156
GLN A 215
LYS A 244
THR A 245
GLN A 284
ASP A 287
MG  A 402 (-2.6A)
MG  A 402 (-2.5A)
C6M  A 401 (-2.7A)
C6M  A 401 (-3.3A)
C6M  A 401 (-2.6A)
C6M  A 401 (-3.6A)
C6M  A 401 (-3.7A)
MG  A 404 ( 2.7A)
0.51A 2e91B-6b07A:
24.3
2e91B-6b07A:
14.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F89_F_210F9001_1
(FARNESYL DIPHOSPHATE
SYNTHASE)
6b07 FARNESYL DIPHOSPHATE
SYNTHASE

(Choristoneura
fumiferana)
9 / 9 ASP A 147
ASP A 151
ARG A 156
LYS A 244
THR A 245
TYR A 248
GLN A 284
ASP A 287
LYS A 301
MG  A 402 (-2.6A)
MG  A 402 (-2.5A)
C6M  A 401 (-2.7A)
C6M  A 401 (-2.6A)
C6M  A 401 (-3.6A)
None
C6M  A 401 (-3.7A)
MG  A 404 ( 2.7A)
C6M  A 401 (-2.9A)
0.41A 2f89F-6b07A:
47.7
2f89F-6b07A:
14.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F8C_F_ZOLF9001_1
(FARNESYL DIPHOSPHATE
SYNTHASE)
6b07 FARNESYL DIPHOSPHATE
SYNTHASE

(Choristoneura
fumiferana)
10 / 11 ASP A 147
ASP A 151
ARG A 156
GLN A 215
LYS A 244
THR A 245
TYR A 248
GLN A 284
ASP A 287
LYS A 301
MG  A 402 (-2.6A)
MG  A 402 (-2.5A)
C6M  A 401 (-2.7A)
C6M  A 401 (-3.3A)
C6M  A 401 (-2.6A)
C6M  A 401 (-3.6A)
None
C6M  A 401 (-3.7A)
MG  A 404 ( 2.7A)
C6M  A 401 (-2.9A)
0.36A 2f8cF-6b07A:
46.9
2f8cF-6b07A:
14.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F8Z_F_ZOLF5001_1
(FARNESYL DIPHOSPHATE
SYNTHASE)
6b07 FARNESYL DIPHOSPHATE
SYNTHASE

(Choristoneura
fumiferana)
9 / 10 ASP A 147
ASP A 151
ARG A 156
GLN A 215
LYS A 244
THR A 245
GLN A 284
ASP A 287
LYS A 301
MG  A 402 (-2.6A)
MG  A 402 (-2.5A)
C6M  A 401 (-2.7A)
C6M  A 401 (-3.3A)
C6M  A 401 (-2.6A)
C6M  A 401 (-3.6A)
C6M  A 401 (-3.7A)
MG  A 404 ( 2.7A)
C6M  A 401 (-2.9A)
0.46A 2f8zF-6b07A:
47.6
2f8zF-6b07A:
14.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F8Z_F_ZOLF5001_1
(FARNESYL DIPHOSPHATE
SYNTHASE)
6b07 FARNESYL DIPHOSPHATE
SYNTHASE

(Choristoneura
fumiferana)
5 / 10 ASP A 151
ARG A 156
GLN A 284
ASP A 287
LYS A 301
MG  A 402 (-2.5A)
C6M  A 401 (-2.7A)
C6M  A 401 (-3.7A)
MG  A 404 ( 2.7A)
C6M  A 401 (-2.9A)
1.24A 2f8zF-6b07A:
47.6
2f8zF-6b07A:
14.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F94_F_BFQF9001_1
(FARNESYL DIPHOSPHATE
SYNTHASE)
6b07 FARNESYL DIPHOSPHATE
SYNTHASE

(Choristoneura
fumiferana)
9 / 12 ASP A 147
ASP A 151
ARG A 156
GLN A 215
LYS A 244
THR A 245
GLN A 284
ASP A 287
LYS A 301
MG  A 402 (-2.6A)
MG  A 402 (-2.5A)
C6M  A 401 (-2.7A)
C6M  A 401 (-3.3A)
C6M  A 401 (-2.6A)
C6M  A 401 (-3.6A)
C6M  A 401 (-3.7A)
MG  A 404 ( 2.7A)
C6M  A 401 (-2.9A)
0.54A 2f94F-6b07A:
46.7
2f94F-6b07A:
14.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F94_F_BFQF9001_1
(FARNESYL DIPHOSPHATE
SYNTHASE)
6b07 FARNESYL DIPHOSPHATE
SYNTHASE

(Choristoneura
fumiferana)
10 / 12 ASP A 147
ASP A 151
ARG A 156
THR A 211
LYS A 244
THR A 245
TYR A 248
GLN A 284
ASP A 287
LYS A 301
MG  A 402 (-2.6A)
MG  A 402 (-2.5A)
C6M  A 401 (-2.7A)
None
C6M  A 401 (-2.6A)
C6M  A 401 (-3.6A)
None
C6M  A 401 (-3.7A)
MG  A 404 ( 2.7A)
C6M  A 401 (-2.9A)
0.30A 2f94F-6b07A:
46.7
2f94F-6b07A:
14.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F9K_F_ZOLF9001_1
(FARNESYL DIPHOSPHATE
SYNTHASE)
6b07 FARNESYL DIPHOSPHATE
SYNTHASE

(Choristoneura
fumiferana)
9 / 10 ASP A 147
ASP A 151
ARG A 156
GLN A 215
LYS A 244
THR A 245
GLN A 284
ASP A 287
LYS A 301
MG  A 402 (-2.6A)
MG  A 402 (-2.5A)
C6M  A 401 (-2.7A)
C6M  A 401 (-3.3A)
C6M  A 401 (-2.6A)
C6M  A 401 (-3.6A)
C6M  A 401 (-3.7A)
MG  A 404 ( 2.7A)
C6M  A 401 (-2.9A)
0.35A 2f9kF-6b07A:
46.7
2f9kF-6b07A:
14.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2O1O_A_RISA400_1
(PUTATIVE FARNESYL
PYROPHOSPHATE
SYNTHASE)
6b07 FARNESYL DIPHOSPHATE
SYNTHASE

(Choristoneura
fumiferana)
7 / 9 ASP A 147
ASP A 151
ARG A 156
GLN A 215
LYS A 244
THR A 245
GLN A 284
MG  A 402 (-2.6A)
MG  A 402 (-2.5A)
C6M  A 401 (-2.7A)
C6M  A 401 (-3.3A)
C6M  A 401 (-2.6A)
C6M  A 401 (-3.6A)
C6M  A 401 (-3.7A)
0.41A 2o1oA-6b07A:
36.1
2o1oA-6b07A:
13.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2O1O_B_RISB400_1
(PUTATIVE FARNESYL
PYROPHOSPHATE
SYNTHASE)
6b07 FARNESYL DIPHOSPHATE
SYNTHASE

(Choristoneura
fumiferana)
6 / 10 ASP A 147
ASP A 151
ARG A 156
GLN A 215
LYS A 244
LYS A 310
MG  A 402 (-2.6A)
MG  A 402 (-2.5A)
C6M  A 401 (-2.7A)
C6M  A 401 (-3.3A)
C6M  A 401 (-2.6A)
MG  A 402 ( 4.3A)
1.18A 2o1oB-6b07A:
36.5
2o1oB-6b07A:
13.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2O1O_B_RISB400_1
(PUTATIVE FARNESYL
PYROPHOSPHATE
SYNTHASE)
6b07 FARNESYL DIPHOSPHATE
SYNTHASE

(Choristoneura
fumiferana)
7 / 10 ASP A 147
ASP A 151
ARG A 156
GLN A 215
LYS A 244
THR A 245
GLN A 284
MG  A 402 (-2.6A)
MG  A 402 (-2.5A)
C6M  A 401 (-2.7A)
C6M  A 401 (-3.3A)
C6M  A 401 (-2.6A)
C6M  A 401 (-3.6A)
C6M  A 401 (-3.7A)
0.43A 2o1oB-6b07A:
36.5
2o1oB-6b07A:
13.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q58_A_ZOLA1_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)
6b07 FARNESYL DIPHOSPHATE
SYNTHASE

(Choristoneura
fumiferana)
8 / 10 ASP A 147
ASP A 151
ARG A 156
GLN A 215
LYS A 244
THR A 245
GLN A 284
ASP A 288
MG  A 402 (-2.6A)
MG  A 402 (-2.5A)
C6M  A 401 (-2.7A)
C6M  A 401 (-3.3A)
C6M  A 401 (-2.6A)
C6M  A 401 (-3.6A)
C6M  A 401 (-3.7A)
None
0.54A 2q58A-6b07A:
35.9
2q58A-6b07A:
13.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q58_B_ZOLB2_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)
6b07 FARNESYL DIPHOSPHATE
SYNTHASE

(Choristoneura
fumiferana)
7 / 9 ASP A 147
ASP A 151
ARG A 156
GLN A 215
LYS A 244
THR A 245
GLN A 284
MG  A 402 (-2.6A)
MG  A 402 (-2.5A)
C6M  A 401 (-2.7A)
C6M  A 401 (-3.3A)
C6M  A 401 (-2.6A)
C6M  A 401 (-3.6A)
C6M  A 401 (-3.7A)
0.49A 2q58B-6b07A:
36.2
2q58B-6b07A:
13.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q58_B_ZOLB2_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)
6b07 FARNESYL DIPHOSPHATE
SYNTHASE

(Choristoneura
fumiferana)
5 / 9 ASP A 147
ASP A 151
GLN A 215
LYS A 244
LYS A 310
MG  A 402 (-2.6A)
MG  A 402 (-2.5A)
C6M  A 401 (-3.3A)
C6M  A 401 (-2.6A)
MG  A 402 ( 4.3A)
1.33A 2q58B-6b07A:
36.2
2q58B-6b07A:
13.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QIS_A_RISA901_1
(FARNESYL
PYROPHOSPHATE
SYNTHETASE)
6b07 FARNESYL DIPHOSPHATE
SYNTHASE

(Choristoneura
fumiferana)
8 / 10 ASP A 147
ASP A 151
ARG A 156
GLN A 215
LYS A 244
GLN A 284
ASP A 287
LYS A 301
MG  A 402 (-2.6A)
MG  A 402 (-2.5A)
C6M  A 401 (-2.7A)
C6M  A 401 (-3.3A)
C6M  A 401 (-2.6A)
C6M  A 401 (-3.7A)
MG  A 404 ( 2.7A)
C6M  A 401 (-2.9A)
0.39A 2qisA-6b07A:
46.3
2qisA-6b07A:
14.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EZ3_A_ZOLA397_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE, PUTATIVE)
6b07 FARNESYL DIPHOSPHATE
SYNTHASE

(Choristoneura
fumiferana)
9 / 9 ASP A 147
ASP A 151
ARG A 156
GLN A 215
LYS A 244
THR A 245
GLN A 284
ASP A 287
LYS A 301
MG  A 402 (-2.6A)
MG  A 402 (-2.5A)
C6M  A 401 (-2.7A)
C6M  A 401 (-3.3A)
C6M  A 401 (-2.6A)
C6M  A 401 (-3.6A)
C6M  A 401 (-3.7A)
MG  A 404 ( 2.7A)
C6M  A 401 (-2.9A)
0.50A 3ez3A-6b07A:
43.4
3ez3A-6b07A:
12.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EZ3_B_ZOLB397_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE, PUTATIVE)
6b07 FARNESYL DIPHOSPHATE
SYNTHASE

(Choristoneura
fumiferana)
9 / 9 ASP A 147
ASP A 151
ARG A 156
GLN A 215
LYS A 244
THR A 245
GLN A 284
ASP A 287
LYS A 301
MG  A 402 (-2.6A)
MG  A 402 (-2.5A)
C6M  A 401 (-2.7A)
C6M  A 401 (-3.3A)
C6M  A 401 (-2.6A)
C6M  A 401 (-3.6A)
C6M  A 401 (-3.7A)
MG  A 404 ( 2.7A)
C6M  A 401 (-2.9A)
0.45A 3ez3B-6b07A:
42.8
3ez3B-6b07A:
12.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EZ3_C_ZOLC397_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE, PUTATIVE)
6b07 FARNESYL DIPHOSPHATE
SYNTHASE

(Choristoneura
fumiferana)
9 / 9 ASP A 147
ASP A 151
ARG A 156
GLN A 215
LYS A 244
THR A 245
GLN A 284
ASP A 287
LYS A 301
MG  A 402 (-2.6A)
MG  A 402 (-2.5A)
C6M  A 401 (-2.7A)
C6M  A 401 (-3.3A)
C6M  A 401 (-2.6A)
C6M  A 401 (-3.6A)
C6M  A 401 (-3.7A)
MG  A 404 ( 2.7A)
C6M  A 401 (-2.9A)
0.50A 3ez3C-6b07A:
43.4
3ez3C-6b07A:
12.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EZ3_D_ZOLD397_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE, PUTATIVE)
6b07 FARNESYL DIPHOSPHATE
SYNTHASE

(Choristoneura
fumiferana)
9 / 10 ASP A 147
ASP A 151
ARG A 156
GLN A 215
LYS A 244
THR A 245
GLN A 284
ASP A 287
LYS A 301
MG  A 402 (-2.6A)
MG  A 402 (-2.5A)
C6M  A 401 (-2.7A)
C6M  A 401 (-3.3A)
C6M  A 401 (-2.6A)
C6M  A 401 (-3.6A)
C6M  A 401 (-3.7A)
MG  A 404 ( 2.7A)
C6M  A 401 (-2.9A)
0.42A 3ez3D-6b07A:
42.3
3ez3D-6b07A:
12.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IBA_A_ZOLA901_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)
6b07 FARNESYL DIPHOSPHATE
SYNTHASE

(Choristoneura
fumiferana)
10 / 10 ASP A 147
ASP A 151
ARG A 156
GLN A 215
LYS A 244
THR A 245
TYR A 248
GLN A 284
ASP A 287
LYS A 301
MG  A 402 (-2.6A)
MG  A 402 (-2.5A)
C6M  A 401 (-2.7A)
C6M  A 401 (-3.3A)
C6M  A 401 (-2.6A)
C6M  A 401 (-3.6A)
None
C6M  A 401 (-3.7A)
MG  A 404 ( 2.7A)
C6M  A 401 (-2.9A)
0.44A 3ibaA-6b07A:
43.8
3ibaA-6b07A:
12.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LDW_A_ZOLA397_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)
6b07 FARNESYL DIPHOSPHATE
SYNTHASE

(Choristoneura
fumiferana)
9 / 9 ASP A 147
ASP A 151
ARG A 156
GLN A 215
LYS A 244
THR A 245
GLN A 284
ASP A 287
LYS A 301
MG  A 402 (-2.6A)
MG  A 402 (-2.5A)
C6M  A 401 (-2.7A)
C6M  A 401 (-3.3A)
C6M  A 401 (-2.6A)
C6M  A 401 (-3.6A)
C6M  A 401 (-3.7A)
MG  A 404 ( 2.7A)
C6M  A 401 (-2.9A)
0.50A 3ldwA-6b07A:
43.4
3ldwA-6b07A:
12.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LDW_B_ZOLB397_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)
6b07 FARNESYL DIPHOSPHATE
SYNTHASE

(Choristoneura
fumiferana)
9 / 9 ASP A 147
ASP A 151
ARG A 156
GLN A 215
LYS A 244
THR A 245
GLN A 284
ASP A 287
LYS A 301
MG  A 402 (-2.6A)
MG  A 402 (-2.5A)
C6M  A 401 (-2.7A)
C6M  A 401 (-3.3A)
C6M  A 401 (-2.6A)
C6M  A 401 (-3.6A)
C6M  A 401 (-3.7A)
MG  A 404 ( 2.7A)
C6M  A 401 (-2.9A)
0.45A 3ldwB-6b07A:
42.7
3ldwB-6b07A:
12.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LDW_C_ZOLC397_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)
6b07 FARNESYL DIPHOSPHATE
SYNTHASE

(Choristoneura
fumiferana)
9 / 9 ASP A 147
ASP A 151
ARG A 156
GLN A 215
LYS A 244
THR A 245
GLN A 284
ASP A 287
LYS A 301
MG  A 402 (-2.6A)
MG  A 402 (-2.5A)
C6M  A 401 (-2.7A)
C6M  A 401 (-3.3A)
C6M  A 401 (-2.6A)
C6M  A 401 (-3.6A)
C6M  A 401 (-3.7A)
MG  A 404 ( 2.7A)
C6M  A 401 (-2.9A)
0.49A 3ldwC-6b07A:
43.3
3ldwC-6b07A:
12.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LDW_D_ZOLD397_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)
6b07 FARNESYL DIPHOSPHATE
SYNTHASE

(Choristoneura
fumiferana)
9 / 9 ASP A 147
ASP A 151
ARG A 156
GLN A 215
LYS A 244
THR A 245
GLN A 284
ASP A 287
LYS A 301
MG  A 402 (-2.6A)
MG  A 402 (-2.5A)
C6M  A 401 (-2.7A)
C6M  A 401 (-3.3A)
C6M  A 401 (-2.6A)
C6M  A 401 (-3.6A)
C6M  A 401 (-3.7A)
MG  A 404 ( 2.7A)
C6M  A 401 (-2.9A)
0.44A 3ldwD-6b07A:
42.3
3ldwD-6b07A:
12.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N45_F_ZOLF354_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)
6b07 FARNESYL DIPHOSPHATE
SYNTHASE

(Choristoneura
fumiferana)
10 / 11 ASP A 147
ASP A 151
ARG A 156
GLN A 215
LYS A 244
THR A 245
TYR A 248
GLN A 284
ASP A 287
LYS A 301
MG  A 402 (-2.6A)
MG  A 402 (-2.5A)
C6M  A 401 (-2.7A)
C6M  A 401 (-3.3A)
C6M  A 401 (-2.6A)
C6M  A 401 (-3.6A)
None
C6M  A 401 (-3.7A)
MG  A 404 ( 2.7A)
C6M  A 401 (-2.9A)
0.37A 3n45F-6b07A:
46.6
3n45F-6b07A:
14.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N46_F_ZOLF354_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)
6b07 FARNESYL DIPHOSPHATE
SYNTHASE

(Choristoneura
fumiferana)
9 / 10 ASP A 147
ASP A 151
ARG A 156
GLN A 215
LYS A 244
THR A 245
GLN A 284
ASP A 287
LYS A 301
MG  A 402 (-2.6A)
MG  A 402 (-2.5A)
C6M  A 401 (-2.7A)
C6M  A 401 (-3.3A)
C6M  A 401 (-2.6A)
C6M  A 401 (-3.6A)
C6M  A 401 (-3.7A)
MG  A 404 ( 2.7A)
C6M  A 401 (-2.9A)
0.43A 3n46F-6b07A:
46.4
3n46F-6b07A:
14.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KFA_A_ZOLA404_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)
6b07 FARNESYL DIPHOSPHATE
SYNTHASE

(Choristoneura
fumiferana)
8 / 9 ASP A 147
ASP A 151
ARG A 156
GLN A 215
LYS A 244
GLN A 284
ASP A 287
LYS A 301
MG  A 402 (-2.6A)
MG  A 402 (-2.5A)
C6M  A 401 (-2.7A)
C6M  A 401 (-3.3A)
C6M  A 401 (-2.6A)
C6M  A 401 (-3.7A)
MG  A 404 ( 2.7A)
C6M  A 401 (-2.9A)
0.48A 4kfaA-6b07A:
46.2
4kfaA-6b07A:
13.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KPD_A_RISA405_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)
6b07 FARNESYL DIPHOSPHATE
SYNTHASE

(Choristoneura
fumiferana)
9 / 10 ASP A 147
ASP A 151
ARG A 156
GLN A 215
LYS A 244
THR A 245
GLN A 284
ASP A 287
LYS A 301
MG  A 402 (-2.6A)
MG  A 402 (-2.5A)
C6M  A 401 (-2.7A)
C6M  A 401 (-3.3A)
C6M  A 401 (-2.6A)
C6M  A 401 (-3.6A)
C6M  A 401 (-3.7A)
MG  A 404 ( 2.7A)
C6M  A 401 (-2.9A)
0.43A 4kpdA-6b07A:
47.5
4kpdA-6b07A:
13.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KPJ_A_210A901_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)
6b07 FARNESYL DIPHOSPHATE
SYNTHASE

(Choristoneura
fumiferana)
8 / 9 ASP A 147
ASP A 151
ARG A 156
LYS A 244
THR A 245
GLN A 284
ASP A 287
LYS A 301
MG  A 402 (-2.6A)
MG  A 402 (-2.5A)
C6M  A 401 (-2.7A)
C6M  A 401 (-2.6A)
C6M  A 401 (-3.6A)
C6M  A 401 (-3.7A)
MG  A 404 ( 2.7A)
C6M  A 401 (-2.9A)
0.43A 4kpjA-6b07A:
46.3
4kpjA-6b07A:
11.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KQ5_A_ZOLA404_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)
6b07 FARNESYL DIPHOSPHATE
SYNTHASE

(Choristoneura
fumiferana)
9 / 10 ASP A 147
ASP A 151
ARG A 156
GLN A 215
LYS A 244
THR A 245
GLN A 284
ASP A 287
LYS A 301
MG  A 402 (-2.6A)
MG  A 402 (-2.5A)
C6M  A 401 (-2.7A)
C6M  A 401 (-3.3A)
C6M  A 401 (-2.6A)
C6M  A 401 (-3.6A)
C6M  A 401 (-3.7A)
MG  A 404 ( 2.7A)
C6M  A 401 (-2.9A)
0.48A 4kq5A-6b07A:
46.5
4kq5A-6b07A:
11.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KQS_A_RISA405_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)
6b07 FARNESYL DIPHOSPHATE
SYNTHASE

(Choristoneura
fumiferana)
9 / 10 ASP A 147
ASP A 151
ARG A 156
GLN A 215
LYS A 244
THR A 245
GLN A 284
ASP A 287
LYS A 301
MG  A 402 (-2.6A)
MG  A 402 (-2.5A)
C6M  A 401 (-2.7A)
C6M  A 401 (-3.3A)
C6M  A 401 (-2.6A)
C6M  A 401 (-3.6A)
C6M  A 401 (-3.7A)
MG  A 404 ( 2.7A)
C6M  A 401 (-2.9A)
0.40A 4kqsA-6b07A:
47.4
4kqsA-6b07A:
11.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N9U_A_RISA404_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)
6b07 FARNESYL DIPHOSPHATE
SYNTHASE

(Choristoneura
fumiferana)
9 / 10 ASP A 147
ASP A 151
ARG A 156
THR A 211
GLN A 215
THR A 245
GLN A 284
ASP A 287
LYS A 301
MG  A 402 (-2.6A)
MG  A 402 (-2.5A)
C6M  A 401 (-2.7A)
None
C6M  A 401 (-3.3A)
C6M  A 401 (-3.6A)
C6M  A 401 (-3.7A)
MG  A 404 ( 2.7A)
C6M  A 401 (-2.9A)
0.42A 4n9uA-6b07A:
27.0
4n9uA-6b07A:
13.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NG6_A_RISA405_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)
6b07 FARNESYL DIPHOSPHATE
SYNTHASE

(Choristoneura
fumiferana)
10 / 12 ASP A 147
ASP A 151
ARG A 156
THR A 211
GLN A 215
THR A 245
TYR A 248
GLN A 284
ASP A 287
LYS A 301
MG  A 402 (-2.6A)
MG  A 402 (-2.5A)
C6M  A 401 (-2.7A)
None
C6M  A 401 (-3.3A)
C6M  A 401 (-3.6A)
None
C6M  A 401 (-3.7A)
MG  A 404 ( 2.7A)
C6M  A 401 (-2.9A)
0.61A 4ng6A-6b07A:
24.5
4ng6A-6b07A:
13.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NKE_A_RISA404_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)
6b07 FARNESYL DIPHOSPHATE
SYNTHASE

(Choristoneura
fumiferana)
9 / 10 ASP A 147
ASP A 151
ARG A 156
GLN A 215
LYS A 244
THR A 245
GLN A 284
ASP A 287
LYS A 301
MG  A 402 (-2.6A)
MG  A 402 (-2.5A)
C6M  A 401 (-2.7A)
C6M  A 401 (-3.3A)
C6M  A 401 (-2.6A)
C6M  A 401 (-3.6A)
C6M  A 401 (-3.7A)
MG  A 404 ( 2.7A)
C6M  A 401 (-2.9A)
0.32A 4nkeA-6b07A:
46.4
4nkeA-6b07A:
13.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NKF_A_210A404_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)
6b07 FARNESYL DIPHOSPHATE
SYNTHASE

(Choristoneura
fumiferana)
8 / 9 ASP A 147
ASP A 151
ARG A 156
LYS A 244
THR A 245
GLN A 284
ASP A 287
LYS A 301
MG  A 402 (-2.6A)
MG  A 402 (-2.5A)
C6M  A 401 (-2.7A)
C6M  A 401 (-2.6A)
C6M  A 401 (-3.6A)
C6M  A 401 (-3.7A)
MG  A 404 ( 2.7A)
C6M  A 401 (-2.9A)
0.44A 4nkfA-6b07A:
46.4
4nkfA-6b07A:
13.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NUA_A_RISA901_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)
6b07 FARNESYL DIPHOSPHATE
SYNTHASE

(Choristoneura
fumiferana)
9 / 10 ASP A 147
ASP A 151
ARG A 156
GLN A 215
LYS A 244
THR A 245
GLN A 284
ASP A 287
LYS A 301
MG  A 402 (-2.6A)
MG  A 402 (-2.5A)
C6M  A 401 (-2.7A)
C6M  A 401 (-3.3A)
C6M  A 401 (-2.6A)
C6M  A 401 (-3.6A)
C6M  A 401 (-3.7A)
MG  A 404 ( 2.7A)
C6M  A 401 (-2.9A)
0.38A 4nuaA-6b07A:
23.5
4nuaA-6b07A:
13.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OGU_A_210A405_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)
6b07 FARNESYL DIPHOSPHATE
SYNTHASE

(Choristoneura
fumiferana)
8 / 9 ASP A 147
ASP A 151
ARG A 156
LYS A 244
THR A 245
GLN A 284
ASP A 287
LYS A 301
MG  A 402 (-2.6A)
MG  A 402 (-2.5A)
C6M  A 401 (-2.7A)
C6M  A 401 (-2.6A)
C6M  A 401 (-3.6A)
C6M  A 401 (-3.7A)
MG  A 404 ( 2.7A)
C6M  A 401 (-2.9A)
0.45A 4oguA-6b07A:
46.2
4oguA-6b07A:
13.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P0V_A_ZOLA401_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)
6b07 FARNESYL DIPHOSPHATE
SYNTHASE

(Choristoneura
fumiferana)
9 / 9 ASP A 147
ASP A 151
ARG A 156
GLN A 215
LYS A 244
THR A 245
GLN A 284
ASP A 287
LYS A 301
MG  A 402 (-2.6A)
MG  A 402 (-2.5A)
C6M  A 401 (-2.7A)
C6M  A 401 (-3.3A)
C6M  A 401 (-2.6A)
C6M  A 401 (-3.6A)
C6M  A 401 (-3.7A)
MG  A 404 ( 2.7A)
C6M  A 401 (-2.9A)
0.34A 4p0vA-6b07A:
47.7
4p0vA-6b07A:
14.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P0W_A_ZOLA501_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)
6b07 FARNESYL DIPHOSPHATE
SYNTHASE

(Choristoneura
fumiferana)
10 / 11 ASP A 147
ASP A 151
ARG A 156
GLN A 215
LYS A 244
THR A 245
TYR A 248
GLN A 284
ASP A 287
LYS A 301
MG  A 402 (-2.6A)
MG  A 402 (-2.5A)
C6M  A 401 (-2.7A)
C6M  A 401 (-3.3A)
C6M  A 401 (-2.6A)
C6M  A 401 (-3.6A)
None
C6M  A 401 (-3.7A)
MG  A 404 ( 2.7A)
C6M  A 401 (-2.9A)
0.39A 4p0wA-6b07A:
47.6
4p0wA-6b07A:
14.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Q23_A_RISA901_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)
6b07 FARNESYL DIPHOSPHATE
SYNTHASE

(Choristoneura
fumiferana)
9 / 10 ASP A 147
ASP A 151
ARG A 156
GLN A 215
LYS A 244
TYR A 248
GLN A 284
ASP A 287
LYS A 301
MG  A 402 (-2.6A)
MG  A 402 (-2.5A)
C6M  A 401 (-2.7A)
C6M  A 401 (-3.3A)
C6M  A 401 (-2.6A)
None
C6M  A 401 (-3.7A)
MG  A 404 ( 2.7A)
C6M  A 401 (-2.9A)
0.38A 4q23A-6b07A:
45.8
4q23A-6b07A:
13.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RXD_A_RISA1404_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)
6b07 FARNESYL DIPHOSPHATE
SYNTHASE

(Choristoneura
fumiferana)
9 / 10 ASP A 147
ASP A 151
ARG A 156
GLN A 215
LYS A 244
THR A 245
GLN A 284
ASP A 287
LYS A 301
MG  A 402 (-2.6A)
MG  A 402 (-2.5A)
C6M  A 401 (-2.7A)
C6M  A 401 (-3.3A)
C6M  A 401 (-2.6A)
C6M  A 401 (-3.6A)
C6M  A 401 (-3.7A)
MG  A 404 ( 2.7A)
C6M  A 401 (-2.9A)
0.29A 4rxdA-6b07A:
43.1
4rxdA-6b07A:
12.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RXD_B_RISB1504_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)
6b07 FARNESYL DIPHOSPHATE
SYNTHASE

(Choristoneura
fumiferana)
9 / 10 ASP A 147
ASP A 151
ARG A 156
GLN A 215
LYS A 244
THR A 245
GLN A 284
ASP A 287
LYS A 301
MG  A 402 (-2.6A)
MG  A 402 (-2.5A)
C6M  A 401 (-2.7A)
C6M  A 401 (-3.3A)
C6M  A 401 (-2.6A)
C6M  A 401 (-3.6A)
C6M  A 401 (-3.7A)
MG  A 404 ( 2.7A)
C6M  A 401 (-2.9A)
0.29A 4rxdB-6b07A:
43.4
4rxdB-6b07A:
12.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RXD_C_RISC1600_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)
6b07 FARNESYL DIPHOSPHATE
SYNTHASE

(Choristoneura
fumiferana)
9 / 10 ASP A 147
ASP A 151
ARG A 156
GLN A 215
LYS A 244
THR A 245
GLN A 284
ASP A 287
LYS A 301
MG  A 402 (-2.6A)
MG  A 402 (-2.5A)
C6M  A 401 (-2.7A)
C6M  A 401 (-3.3A)
C6M  A 401 (-2.6A)
C6M  A 401 (-3.6A)
C6M  A 401 (-3.7A)
MG  A 404 ( 2.7A)
C6M  A 401 (-2.9A)
0.30A 4rxdC-6b07A:
43.4
4rxdC-6b07A:
12.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UMJ_A_BFQA1297_1
(GERANYLTRANSTRANSFER
ASE)
6b07 FARNESYL DIPHOSPHATE
SYNTHASE

(Choristoneura
fumiferana)
5 / 8 ASP A 147
ASP A 151
ARG A 156
GLN A 215
LYS A 244
MG  A 402 (-2.6A)
MG  A 402 (-2.5A)
C6M  A 401 (-2.7A)
C6M  A 401 (-3.3A)
C6M  A 401 (-2.6A)
0.65A 4umjA-6b07A:
23.2
4umjA-6b07A:
12.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UMJ_B_BFQB1294_1
(GERANYLTRANSTRANSFER
ASE)
6b07 FARNESYL DIPHOSPHATE
SYNTHASE

(Choristoneura
fumiferana)
6 / 9 ASP A 147
ASP A 151
ARG A 156
GLN A 215
LYS A 244
THR A 245
MG  A 402 (-2.6A)
MG  A 402 (-2.5A)
C6M  A 401 (-2.7A)
C6M  A 401 (-3.3A)
C6M  A 401 (-2.6A)
C6M  A 401 (-3.6A)
0.55A 4umjB-6b07A:
23.2
4umjB-6b07A:
12.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CG5_A_RISA400_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)
6b07 FARNESYL DIPHOSPHATE
SYNTHASE

(Choristoneura
fumiferana)
11 / 12 ASP A 147
ASP A 151
ARG A 156
THR A 211
GLN A 215
LYS A 244
THR A 245
TYR A 248
GLN A 284
ASP A 287
LYS A 301
MG  A 402 (-2.6A)
MG  A 402 (-2.5A)
C6M  A 401 (-2.7A)
None
C6M  A 401 (-3.3A)
C6M  A 401 (-2.6A)
C6M  A 401 (-3.6A)
None
C6M  A 401 (-3.7A)
MG  A 404 ( 2.7A)
C6M  A 401 (-2.9A)
0.25A 5cg5A-6b07A:
45.9
5cg5A-6b07A:
14.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CG6_A_RISA404_1
(FARNESYL
PYROPHOSPHATE
SYNTHASE)
6b07 FARNESYL DIPHOSPHATE
SYNTHASE

(Choristoneura
fumiferana)
10 / 12 ASP A 147
ASP A 151
ARG A 156
THR A 211
GLN A 215
LYS A 244
THR A 245
GLN A 284
ASP A 287
LYS A 301
MG  A 402 (-2.6A)
MG  A 402 (-2.5A)
C6M  A 401 (-2.7A)
None
C6M  A 401 (-3.3A)
C6M  A 401 (-2.6A)
C6M  A 401 (-3.6A)
C6M  A 401 (-3.7A)
MG  A 404 ( 2.7A)
C6M  A 401 (-2.9A)
0.38A 5cg6A-6b07A:
46.2
5cg6A-6b07A:
14.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D4U_A_SAMA301_0
(UNCHARACTERIZED
PROTEIN MJ0489)
6b07 FARNESYL DIPHOSPHATE
SYNTHASE

(Choristoneura
fumiferana)
5 / 12 LEU A 106
ILE A 279
MET A 391
THR A 249
GLY A 133
None
None
None
C6M  A 401 ( 4.9A)
None
1.09A 5d4uA-6b07A:
undetectable
5d4uA-6b07A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D4U_B_SAMB301_0
(UNCHARACTERIZED
PROTEIN MJ0489)
6b07 FARNESYL DIPHOSPHATE
SYNTHASE

(Choristoneura
fumiferana)
5 / 12 LEU A 106
ILE A 279
MET A 391
THR A 249
GLY A 133
None
None
None
C6M  A 401 ( 4.9A)
None
1.07A 5d4uB-6b07A:
undetectable
5d4uB-6b07A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ERO_A_210A804_1
(FUSICOCCADIENE
SYNTHASE)
6b07 FARNESYL DIPHOSPHATE
SYNTHASE

(Choristoneura
fumiferana)
6 / 9 ASP A 147
ASP A 151
ARG A 156
LYS A 244
GLN A 284
ASP A 287
MG  A 402 (-2.6A)
MG  A 402 (-2.5A)
C6M  A 401 (-2.7A)
C6M  A 401 (-2.6A)
C6M  A 401 (-3.7A)
MG  A 404 ( 2.7A)
0.53A 5eroA-6b07A:
27.4
5eroA-6b07A:
11.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ERO_B_210B804_1
(FUSICOCCADIENE
SYNTHASE)
6b07 FARNESYL DIPHOSPHATE
SYNTHASE

(Choristoneura
fumiferana)
5 / 9 ARG A 156
LYS A 244
GLN A 284
ASP A 288
LYS A 301
C6M  A 401 (-2.7A)
C6M  A 401 (-2.6A)
C6M  A 401 (-3.7A)
None
C6M  A 401 (-2.9A)
1.25A 5eroB-6b07A:
26.9
5eroB-6b07A:
11.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ERO_B_210B804_1
(FUSICOCCADIENE
SYNTHASE)
6b07 FARNESYL DIPHOSPHATE
SYNTHASE

(Choristoneura
fumiferana)
7 / 9 ASP A 147
ASP A 151
ARG A 156
LYS A 244
GLN A 284
ASP A 287
ASP A 288
MG  A 402 (-2.6A)
MG  A 402 (-2.5A)
C6M  A 401 (-2.7A)
C6M  A 401 (-2.6A)
C6M  A 401 (-3.7A)
MG  A 404 ( 2.7A)
None
0.58A 5eroB-6b07A:
26.9
5eroB-6b07A:
11.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ERO_B_210B804_1
(FUSICOCCADIENE
SYNTHASE)
6b07 FARNESYL DIPHOSPHATE
SYNTHASE

(Choristoneura
fumiferana)
5 / 9 ASP A 147
ASP A 151
LYS A 244
GLN A 284
ASP A 287
MG  A 402 (-2.6A)
MG  A 402 (-2.5A)
C6M  A 401 (-2.6A)
C6M  A 401 (-3.7A)
MG  A 404 ( 2.7A)
1.49A 5eroB-6b07A:
26.9
5eroB-6b07A:
11.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ERO_C_210C804_1
(FUSICOCCADIENE
SYNTHASE)
6b07 FARNESYL DIPHOSPHATE
SYNTHASE

(Choristoneura
fumiferana)
8 / 10 ASP A 147
ASP A 148
ASP A 151
ARG A 156
LYS A 244
GLN A 284
ASP A 287
ASP A 288
MG  A 402 (-2.6A)
None
MG  A 402 (-2.5A)
C6M  A 401 (-2.7A)
C6M  A 401 (-2.6A)
C6M  A 401 (-3.7A)
MG  A 404 ( 2.7A)
None
0.62A 5eroC-6b07A:
27.3
5eroC-6b07A:
11.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ERO_C_210C804_1
(FUSICOCCADIENE
SYNTHASE)
6b07 FARNESYL DIPHOSPHATE
SYNTHASE

(Choristoneura
fumiferana)
8 / 10 ASP A 147
ASP A 151
ARG A 156
LYS A 244
GLN A 284
ASP A 287
ASP A 288
LYS A 301
MG  A 402 (-2.6A)
MG  A 402 (-2.5A)
C6M  A 401 (-2.7A)
C6M  A 401 (-2.6A)
C6M  A 401 (-3.7A)
MG  A 404 ( 2.7A)
None
C6M  A 401 (-2.9A)
0.94A 5eroC-6b07A:
27.3
5eroC-6b07A:
11.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ERO_C_210C804_1
(FUSICOCCADIENE
SYNTHASE)
6b07 FARNESYL DIPHOSPHATE
SYNTHASE

(Choristoneura
fumiferana)
5 / 10 ASP A 147
ASP A 151
LYS A 244
GLN A 284
ASP A 287
MG  A 402 (-2.6A)
MG  A 402 (-2.5A)
C6M  A 401 (-2.6A)
C6M  A 401 (-3.7A)
MG  A 404 ( 2.7A)
1.47A 5eroC-6b07A:
27.3
5eroC-6b07A:
11.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ERO_C_210C804_1
(FUSICOCCADIENE
SYNTHASE)
6b07 FARNESYL DIPHOSPHATE
SYNTHASE

(Choristoneura
fumiferana)
5 / 10 ASP A 147
GLN A 284
ASP A 287
ASP A 288
LYS A 301
MG  A 402 (-2.6A)
C6M  A 401 (-3.7A)
MG  A 404 ( 2.7A)
None
C6M  A 401 (-2.9A)
1.32A 5eroC-6b07A:
27.3
5eroC-6b07A:
11.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ERO_C_210C804_1
(FUSICOCCADIENE
SYNTHASE)
6b07 FARNESYL DIPHOSPHATE
SYNTHASE

(Choristoneura
fumiferana)
6 / 10 ASP A 151
ASP A 148
ARG A 156
GLN A 284
ASP A 287
ASP A 288
MG  A 402 (-2.5A)
None
C6M  A 401 (-2.7A)
C6M  A 401 (-3.7A)
MG  A 404 ( 2.7A)
None
1.33A 5eroC-6b07A:
27.3
5eroC-6b07A:
11.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G31_A_ZOLA401_0
(GERANYLGERANYL
PYROPHOSPHATE
SYNTHASE)
6b07 FARNESYL DIPHOSPHATE
SYNTHASE

(Choristoneura
fumiferana)
6 / 7 ASP A 147
ASP A 151
ARG A 156
GLN A 215
LYS A 244
GLN A 284
MG  A 402 (-2.6A)
MG  A 402 (-2.5A)
C6M  A 401 (-2.7A)
C6M  A 401 (-3.3A)
C6M  A 401 (-2.6A)
C6M  A 401 (-3.7A)
0.95A 6g31A-6b07A:
26.3
6g31A-6b07A:
24.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G31_B_ZOLB401_0
(GERANYLGERANYL
PYROPHOSPHATE
SYNTHASE)
6b07 FARNESYL DIPHOSPHATE
SYNTHASE

(Choristoneura
fumiferana)
5 / 6 ASP A 147
ASP A 151
ARG A 156
GLN A 215
GLN A 284
MG  A 402 (-2.6A)
MG  A 402 (-2.5A)
C6M  A 401 (-2.7A)
C6M  A 401 (-3.3A)
C6M  A 401 (-3.7A)
0.62A 6g31B-6b07A:
26.4
6g31B-6b07A:
24.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G31_C_ZOLC401_0
(GERANYLGERANYL
PYROPHOSPHATE
SYNTHASE)
6b07 FARNESYL DIPHOSPHATE
SYNTHASE

(Choristoneura
fumiferana)
5 / 5 ASP A 147
ASP A 151
ARG A 156
GLN A 215
LYS A 244
MG  A 402 (-2.6A)
MG  A 402 (-2.5A)
C6M  A 401 (-2.7A)
C6M  A 401 (-3.3A)
C6M  A 401 (-2.6A)
1.15A 6g31C-6b07A:
26.7
6g31C-6b07A:
24.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G31_D_ZOLD401_0
(GERANYLGERANYL
PYROPHOSPHATE
SYNTHASE)
6b07 FARNESYL DIPHOSPHATE
SYNTHASE

(Choristoneura
fumiferana)
5 / 7 ASP A 147
ASP A 151
ARG A 156
GLN A 215
GLN A 284
MG  A 402 (-2.6A)
MG  A 402 (-2.5A)
C6M  A 401 (-2.7A)
C6M  A 401 (-3.3A)
C6M  A 401 (-3.7A)
0.48A 6g31D-6b07A:
25.8
6g31D-6b07A:
24.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G31_F_ZOLF401_0
(GERANYLGERANYL
PYROPHOSPHATE
SYNTHASE)
6b07 FARNESYL DIPHOSPHATE
SYNTHASE

(Choristoneura
fumiferana)
5 / 5 ASP A 147
ASP A 151
ARG A 156
GLN A 215
GLN A 284
MG  A 402 (-2.6A)
MG  A 402 (-2.5A)
C6M  A 401 (-2.7A)
C6M  A 401 (-3.3A)
C6M  A 401 (-3.7A)
0.51A 6g31F-6b07A:
26.4
6g31F-6b07A:
24.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G31_G_ZOLG401_0
(GERANYLGERANYL
PYROPHOSPHATE
SYNTHASE)
6b07 FARNESYL DIPHOSPHATE
SYNTHASE

(Choristoneura
fumiferana)
6 / 7 ASP A 147
ASP A 151
ARG A 156
GLN A 215
LYS A 244
GLN A 284
MG  A 402 (-2.6A)
MG  A 402 (-2.5A)
C6M  A 401 (-2.7A)
C6M  A 401 (-3.3A)
C6M  A 401 (-2.6A)
C6M  A 401 (-3.7A)
0.51A 6g31G-6b07A:
25.6
6g31G-6b07A:
24.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G31_H_ZOLH401_0
(GERANYLGERANYL
PYROPHOSPHATE
SYNTHASE)
6b07 FARNESYL DIPHOSPHATE
SYNTHASE

(Choristoneura
fumiferana)
4 / 5 ASP A 147
ASP A 151
GLN A 215
GLN A 284
MG  A 402 (-2.6A)
MG  A 402 (-2.5A)
C6M  A 401 (-3.3A)
C6M  A 401 (-3.7A)
0.45A 6g31H-6b07A:
25.4
6g31H-6b07A:
24.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G31_H_ZOLH401_0
(GERANYLGERANYL
PYROPHOSPHATE
SYNTHASE)
6b07 FARNESYL DIPHOSPHATE
SYNTHASE

(Choristoneura
fumiferana)
4 / 5 ASP A 147
ASP A 151
GLN A 215
LYS A 310
MG  A 402 (-2.6A)
MG  A 402 (-2.5A)
C6M  A 401 (-3.3A)
MG  A 402 ( 4.3A)
1.42A 6g31H-6b07A:
25.4
6g31H-6b07A:
24.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G31_I_ZOLI401_0
(GERANYLGERANYL
PYROPHOSPHATE
SYNTHASE)
6b07 FARNESYL DIPHOSPHATE
SYNTHASE

(Choristoneura
fumiferana)
4 / 4 ASP A 147
ASP A 151
LYS A 244
GLN A 284
MG  A 402 (-2.6A)
MG  A 402 (-2.5A)
C6M  A 401 (-2.6A)
C6M  A 401 (-3.7A)
0.90A 6g31I-6b07A:
25.7
6g31I-6b07A:
24.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G31_J_ZOLJ401_0
(GERANYLGERANYL
PYROPHOSPHATE
SYNTHASE)
6b07 FARNESYL DIPHOSPHATE
SYNTHASE

(Choristoneura
fumiferana)
5 / 6 ASP A 147
ASP A 151
ARG A 156
GLN A 215
GLN A 284
MG  A 402 (-2.6A)
MG  A 402 (-2.5A)
C6M  A 401 (-2.7A)
C6M  A 401 (-3.3A)
C6M  A 401 (-3.7A)
0.81A 6g31J-6b07A:
26.8
6g31J-6b07A:
24.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G31_K_ZOLK401_0
(GERANYLGERANYL
PYROPHOSPHATE
SYNTHASE)
6b07 FARNESYL DIPHOSPHATE
SYNTHASE

(Choristoneura
fumiferana)
4 / 4 ASP A 147
ASP A 151
ARG A 156
GLN A 215
MG  A 402 (-2.6A)
MG  A 402 (-2.5A)
C6M  A 401 (-2.7A)
C6M  A 401 (-3.3A)
0.47A 6g31K-6b07A:
24.9
6g31K-6b07A:
24.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G31_L_ZOLL401_0
(GERANYLGERANYL
PYROPHOSPHATE
SYNTHASE)
6b07 FARNESYL DIPHOSPHATE
SYNTHASE

(Choristoneura
fumiferana)
5 / 6 ASP A 147
ASP A 151
ARG A 156
GLN A 215
GLN A 284
MG  A 402 (-2.6A)
MG  A 402 (-2.5A)
C6M  A 401 (-2.7A)
C6M  A 401 (-3.3A)
C6M  A 401 (-3.7A)
0.76A 6g31L-6b07A:
26.4
6g31L-6b07A:
24.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G31_L_ZOLL401_0
(GERANYLGERANYL
PYROPHOSPHATE
SYNTHASE)
6b07 FARNESYL DIPHOSPHATE
SYNTHASE

(Choristoneura
fumiferana)
5 / 6 ASP A 147
ASP A 151
GLN A 215
GLN A 284
LYS A 310
MG  A 402 (-2.6A)
MG  A 402 (-2.5A)
C6M  A 401 (-3.3A)
C6M  A 401 (-3.7A)
MG  A 402 ( 4.3A)
1.08A 6g31L-6b07A:
26.4
6g31L-6b07A:
24.14