SIMILAR PATTERN OF AMINO ACIDS MAPPED TO 'C3Y'


List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XZ5_C_ACHC1211_0
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 2uxy ALIPHATIC AMIDASE
(Pseudomonas
aeruginosa) 		4 / 8 THR A  75
GLN A  63
TYR A  60
TRP A 144
 None
None
C3Y  A 166 ( 4.9A)
None
 1.40A 2xz5A-2uxyA:
undetectable
2xz5C-2uxyA:
undetectable		 2xz5A-2uxyA:
21.16
2xz5C-2uxyA:
21.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KU9_B_SPMB700_1
(POLYAMINE OXIDASE)		 2uxy ALIPHATIC AMIDASE
(Pseudomonas
aeruginosa) 		4 / 7 GLU A  59
GLU A 142
TYR A 192
TYR A  60
 C3Y  A 166 ( 2.8A)
C3Y  A 166 ( 3.4A)
C3Y  A 166 ( 3.3A)
C3Y  A 166 ( 4.9A)
 1.15A 3ku9B-2uxyA:
undetectable		 3ku9B-2uxyA:
20.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DWD_C_GLYC713_0
(DEOXYNUCLEOSIDE
TRIPHOSPHATE
TRIPHOSPHOHYDROLASE
SAMHD1)		 2uxy ALIPHATIC AMIDASE
(Pseudomonas
aeruginosa) 		3 / 3 GLN A 190
TYR A 192
ASN A 219
 C3Y  A 166 ( 4.8A)
C3Y  A 166 ( 3.3A)
None
 1.00A 6dwdC-2uxyA:
undetectable		 6dwdC-2uxyA:
18.77