SIMILAR PATTERN OF AMINO ACIDS MAPPED TO 'C3H'


List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LIN_A_TFPA155_1
(CALMODULIN)		 6exs PEPTIDE ABC
TRANSPORTER PERMEASE
(Staphylococcus
hominis) 		4 / 7 GLN A 344
MET A  43
PHE A 257
MET A  51
 C3H  A 514 (-2.8A)
None
None
None
 1.28A 1linA-6exsA:
undetectable		 1linA-6exsA:
17.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IB2_A_IBPA3960_1
(LACTOTRANSFERRIN)		 6exs PEPTIDE ABC
TRANSPORTER PERMEASE
(Staphylococcus
hominis) 		4 / 4 GLY A 313
VAL A 316
GLY A 457
THR A 458
 C3H  A 514 (-3.3A)
None
None
None
 0.90A 3ib2A-6exsA:
undetectable		 3ib2A-6exsA:
10.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J4V_C_SVRC301_1
(NUCLEOCAPSID PROTEIN)		 6exs PEPTIDE ABC
TRANSPORTER PERMEASE
(Staphylococcus
hominis) 		4 / 8 GLY A 313
ASN A 318
PHE A 472
ILE A 390
 C3H  A 514 (-3.3A)
None
None
None
 0.91A 4j4vC-6exsA:
undetectable		 4j4vC-6exsA:
15.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XE5_A_OBNA1104_1
(SODIUM/POTASSIUM-TRA
NSPORTING ATPASE
SUBUNIT ALPHA-1)		 6exs PEPTIDE ABC
TRANSPORTER PERMEASE
(Staphylococcus
hominis) 		5 / 12 GLN A 344
GLU A 340
GLY A  42
GLU A  36
ILE A 129
 C3H  A 514 (-2.8A)
None
None
None
None
 1.27A 4xe5A-6exsA:
undetectable		 4xe5A-6exsA:
5.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GS4_A_F9EA601_0
(DIPEPTIDE AND
TRIPEPTIDE PERMEASE
A)		 6exs PEPTIDE ABC
TRANSPORTER PERMEASE
(Staphylococcus
hominis) 		5 / 10 TYR A  41
ASN A 167
ASN A 347
PRO A 348
GLU A 418
 C3H  A 514 (-4.0A)
C3H  A 514 (-3.6A)
C3H  A 514 (-4.0A)
C3H  A 514 (-4.1A)
None
 0.61A 6gs4A-6exsA:
37.1		 6gs4A-6exsA:
undetectable
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6GZ9_A_TXCA501_0
(PEPTIDE ABC
TRANSPORTER PERMEASE)		 6exs PEPTIDE ABC
TRANSPORTER PERMEASE
(Staphylococcus
hominis) 		10 / 10 TYR A  41
TYR A  79
TYR A 163
VAL A 166
ASN A 167
ALA A 170
GLN A 310
ASN A 347
PRO A 348
ASN A 426
 C3H  A 514 (-4.0A)
None
None
None
C3H  A 514 (-3.6A)
C3H  A 514 ( 3.7A)
C3H  A 514 (-3.5A)
C3H  A 514 (-4.0A)
C3H  A 514 (-4.1A)
None
 0.56A 6gz9A-6exsA:
60.6		 6gz9A-6exsA:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6H7U_A_FVTA501_0
(PEPTIDE ABC
TRANSPORTER PERMEASE)		 6exs PEPTIDE ABC
TRANSPORTER PERMEASE
(Staphylococcus
hominis) 		6 / 6 VAL A 166
ASN A 167
ASN A 347
PRO A 348
ILE A 351
GLU A 418
 None
C3H  A 514 (-3.6A)
C3H  A 514 (-4.0A)
C3H  A 514 (-4.1A)
None
None
 0.53A 6h7uA-6exsA:
61.8		 6h7uA-6exsA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HZP_A_FVTA501_0
(PEPTIDE ABC
TRANSPORTER PERMEASE)		 6exs PEPTIDE ABC
TRANSPORTER PERMEASE
(Staphylococcus
hominis) 		8 / 8 TYR A  41
VAL A 166
ASN A 167
GLN A 310
ASN A 347
PRO A 348
ILE A 351
GLU A 418
 C3H  A 514 (-4.0A)
None
C3H  A 514 (-3.6A)
C3H  A 514 (-3.5A)
C3H  A 514 (-4.0A)
C3H  A 514 (-4.1A)
None
None
 0.24A 6hzpA-6exsA:
62.6		 6hzpA-6exsA:
undetectable