SIMILAR PATTERN OF AMINO ACIDS MAPPED TO 'C0T'


List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BUR_B_TESB340_1
(3-OXO-5-BETA-STEROID
4-DEHYDROGENASE)		 3rsc CALG2
(Micromonospora
echinospora) 		5 / 10 TYR A  80
ASN A 180
TRP A 179
VAL A 176
VAL A 175
 C0T  A 398 (-3.3A)
None
None
None
None
 1.44A 3burB-3rscA:
undetectable		 3burB-3rscA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CAS_A_ASDA332_1
(3-OXO-5-BETA-STEROID
4-DEHYDROGENASE)		 3rsc CALG2
(Micromonospora
echinospora) 		5 / 10 TYR A  80
TRP A 179
VAL A 176
VAL A 175
LEU A 162
 C0T  A 398 (-3.3A)
None
None
None
None
 1.42A 3casA-3rscA:
undetectable		 3casA-3rscA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NUV_B_ASDB126_1
(STEROID
DELTA-ISOMERASE)		 3rsc CALG2
(Micromonospora
echinospora) 		5 / 10 TYR A  80
LEU A  14
VAL A   9
ASN A  84
ALA A 112
 C0T  A 398 (-3.3A)
None
None
None
None
 1.42A 3nuvB-3rscA:
undetectable		 3nuvB-3rscA:
15.66