SIMILAR PATTERN OF AMINO ACIDS MAPPED TO 'BZC'
DrReposER ID / Desc. | Hit PDBID |
Hit Macromolecule |
Res. Matches |
Interface | HETATM | RMSD | Dali Z-score |
Seq. Identity (%) |
View | Dock | |
---|---|---|---|---|---|---|---|---|---|---|---|
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1DMA_A_NCAA700_0 (EXOTOXIN A) |
1efy | POLY (ADP-RIBOSE)POLYMERASE (Gallusgallus) | 5 / 7 | HIS A 862GLY A 863TYR A 896TYR A 907GLU A 988 | BZC A 201 (-4.0A)BZC A 201 (-3.9A)BZC A 201 (-4.0A)BZC A 201 (-3.6A)BZC A 201 (-4.0A) | 0.51A | 1dmaA-1efyA:5.8 | 1dmaA-1efyA:20.23 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1DMA_B_NCAB700_0 (EXOTOXIN A) |
1efy | POLY (ADP-RIBOSE)POLYMERASE (Gallusgallus) | 6 / 6 | HIS A 862GLY A 863TYR A 896ALA A 898TYR A 907GLU A 988 | BZC A 201 (-4.0A)BZC A 201 (-3.9A)BZC A 201 (-4.0A)BZC A 201 ( 3.9A)BZC A 201 (-3.6A)BZC A 201 (-4.0A) | 0.44A | 1dmaB-1efyA:5.6 | 1dmaB-1efyA:20.23 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3U9H_A_NCAA1163_0 (TANKYRASE-2) |
1efy | POLY (ADP-RIBOSE)POLYMERASE (Gallusgallus) | 7 / 8 | HIS A 862GLY A 863ALA A 898LYS A 903SER A 904TYR A 907GLU A 988 | BZC A 201 (-4.0A)BZC A 201 (-3.9A)BZC A 201 ( 3.9A)BZC A 201 ( 4.8A)BZC A 201 (-3.3A)BZC A 201 (-3.6A)BZC A 201 (-4.0A) | 1.25A | 3u9hA-1efyA:19.0 | 3u9hA-1efyA:23.42 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3U9H_A_NCAA1163_0 (TANKYRASE-2) |
1efy | POLY (ADP-RIBOSE)POLYMERASE (Gallusgallus) | 7 / 8 | HIS A 862GLY A 863TYR A 896ALA A 898LYS A 903SER A 904TYR A 907 | BZC A 201 (-4.0A)BZC A 201 (-3.9A)BZC A 201 (-4.0A)BZC A 201 ( 3.9A)BZC A 201 ( 4.8A)BZC A 201 (-3.3A)BZC A 201 (-3.6A) | 0.92A | 3u9hA-1efyA:19.0 | 3u9hA-1efyA:23.42 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3U9H_B_NCAB1164_0 (TANKYRASE-2) |
1efy | POLY (ADP-RIBOSE)POLYMERASE (Gallusgallus) | 7 / 8 | HIS A 862GLY A 863ALA A 898LYS A 903SER A 904TYR A 907GLU A 988 | BZC A 201 (-4.0A)BZC A 201 (-3.9A)BZC A 201 ( 3.9A)BZC A 201 ( 4.8A)BZC A 201 (-3.3A)BZC A 201 (-3.6A)BZC A 201 (-4.0A) | 1.24A | 3u9hB-1efyA:19.0 | 3u9hB-1efyA:23.42 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3U9H_B_NCAB1164_0 (TANKYRASE-2) |
1efy | POLY (ADP-RIBOSE)POLYMERASE (Gallusgallus) | 7 / 8 | HIS A 862GLY A 863TYR A 896ALA A 898LYS A 903SER A 904TYR A 907 | BZC A 201 (-4.0A)BZC A 201 (-3.9A)BZC A 201 (-4.0A)BZC A 201 ( 3.9A)BZC A 201 ( 4.8A)BZC A 201 (-3.3A)BZC A 201 (-3.6A) | 0.96A | 3u9hB-1efyA:19.0 | 3u9hB-1efyA:23.42 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4AE1_A_NCAA1536_0 (DIPHTHERIA TOXIN) |
1efy | POLY (ADP-RIBOSE)POLYMERASE (Gallusgallus) | 5 / 6 | HIS A 862GLY A 863TYR A 896TYR A 907GLU A 988 | BZC A 201 (-4.0A)BZC A 201 (-3.9A)BZC A 201 (-4.0A)BZC A 201 (-3.6A)BZC A 201 (-4.0A) | 0.43A | 4ae1A-1efyA:6.4 | 4ae1A-1efyA:21.45 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4AE1_B_NCAB1536_0 (DIPHTHERIA TOXIN) |
1efy | POLY (ADP-RIBOSE)POLYMERASE (Gallusgallus) | 5 / 5 | HIS A 862GLY A 863TYR A 896TYR A 907GLU A 988 | BZC A 201 (-4.0A)BZC A 201 (-3.9A)BZC A 201 (-4.0A)BZC A 201 (-3.6A)BZC A 201 (-4.0A) | 0.46A | 4ae1B-1efyA:0.1 | 4ae1B-1efyA:21.45 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4BJC_A_RPBA2162_1 (TANKYRASE-2) |
1efy | POLY (ADP-RIBOSE)POLYMERASE (Gallusgallus) | 6 / 8 | HIS A 862GLY A 863ALA A 898LYS A 903SER A 904GLU A 988 | BZC A 201 (-4.0A)BZC A 201 (-3.9A)BZC A 201 ( 3.9A)BZC A 201 ( 4.8A)BZC A 201 (-3.3A)BZC A 201 (-4.0A) | 1.30A | 4bjcA-1efyA:18.7 | 4bjcA-1efyA:23.42 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4BJC_A_RPBA2162_1 (TANKYRASE-2) |
1efy | POLY (ADP-RIBOSE)POLYMERASE (Gallusgallus) | 6 / 8 | HIS A 862GLY A 863ALA A 898SER A 904TYR A 907GLU A 988 | BZC A 201 (-4.0A)BZC A 201 (-3.9A)BZC A 201 ( 3.9A)BZC A 201 (-3.3A)BZC A 201 (-3.6A)BZC A 201 (-4.0A) | 0.78A | 4bjcA-1efyA:18.7 | 4bjcA-1efyA:23.42 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4BJC_A_RPBA2162_1 (TANKYRASE-2) |
1efy | POLY (ADP-RIBOSE)POLYMERASE (Gallusgallus) | 6 / 8 | HIS A 862GLY A 863TYR A 896ALA A 898LYS A 903SER A 904 | BZC A 201 (-4.0A)BZC A 201 (-3.9A)BZC A 201 (-4.0A)BZC A 201 ( 3.9A)BZC A 201 ( 4.8A)BZC A 201 (-3.3A) | 0.91A | 4bjcA-1efyA:18.7 | 4bjcA-1efyA:23.42 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4BJC_A_RPBA2162_1 (TANKYRASE-2) |
1efy | POLY (ADP-RIBOSE)POLYMERASE (Gallusgallus) | 6 / 8 | HIS A 862GLY A 863TYR A 896ALA A 898SER A 904TYR A 907 | BZC A 201 (-4.0A)BZC A 201 (-3.9A)BZC A 201 (-4.0A)BZC A 201 ( 3.9A)BZC A 201 (-3.3A)BZC A 201 (-3.6A) | 0.27A | 4bjcA-1efyA:18.7 | 4bjcA-1efyA:23.42 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4HYF_A_NCAA1201_0 (TANKYRASE-2) |
1efy | POLY (ADP-RIBOSE)POLYMERASE (Gallusgallus) | 7 / 7 | HIS A 862GLY A 863TYR A 896ALA A 898SER A 904TYR A 907GLU A 988 | BZC A 201 (-4.0A)BZC A 201 (-3.9A)BZC A 201 (-4.0A)BZC A 201 ( 3.9A)BZC A 201 (-3.3A)BZC A 201 (-3.6A)BZC A 201 (-4.0A) | 0.58A | 4hyfA-1efyA:19.9 | 4hyfA-1efyA:23.42 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4HYF_B_NCAB1201_0 (TANKYRASE-2) |
1efy | POLY (ADP-RIBOSE)POLYMERASE (Gallusgallus) | 8 / 8 | HIS A 862GLY A 863TYR A 896ALA A 898LYS A 903SER A 904TYR A 907GLU A 988 | BZC A 201 (-4.0A)BZC A 201 (-3.9A)BZC A 201 (-4.0A)BZC A 201 ( 3.9A)BZC A 201 ( 4.8A)BZC A 201 (-3.3A)BZC A 201 (-3.6A)BZC A 201 (-4.0A) | 0.86A | 4hyfB-1efyA:20.0 | 4hyfB-1efyA:23.42 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4HYF_C_NCAC1201_0 (TANKYRASE-2) |
1efy | POLY (ADP-RIBOSE)POLYMERASE (Gallusgallus) | 8 / 8 | HIS A 862GLY A 863TYR A 896ALA A 898LYS A 903SER A 904TYR A 907GLU A 988 | BZC A 201 (-4.0A)BZC A 201 (-3.9A)BZC A 201 (-4.0A)BZC A 201 ( 3.9A)BZC A 201 ( 4.8A)BZC A 201 (-3.3A)BZC A 201 (-3.6A)BZC A 201 (-4.0A) | 0.53A | 4hyfC-1efyA:20.0 | 4hyfC-1efyA:23.42 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4RV6_A_RPBA1103_1 (POLY [ADP-RIBOSE]POLYMERASE 1) |
1efy | POLY (ADP-RIBOSE)POLYMERASE (Gallusgallus) | 5 / 11 | GLN A 763TYR A 896ALA A 898LYS A 903GLU A 988 | BZC A 201 (-3.8A)BZC A 201 (-4.0A)BZC A 201 ( 3.9A)BZC A 201 ( 4.8A)BZC A 201 (-4.0A) | 0.92A | 4rv6A-1efyA:52.2 | 4rv6A-1efyA:86.57 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4RV6_A_RPBA1103_1 (POLY [ADP-RIBOSE]POLYMERASE 1) |
1efy | POLY (ADP-RIBOSE)POLYMERASE (Gallusgallus) | 9 / 11 | HIS A 862GLY A 863TYR A 889TYR A 896ALA A 898LYS A 903SER A 904TYR A 907GLU A 988 | BZC A 201 (-4.0A)BZC A 201 (-3.9A)NoneBZC A 201 (-4.0A)BZC A 201 ( 3.9A)BZC A 201 ( 4.8A)BZC A 201 (-3.3A)BZC A 201 (-3.6A)BZC A 201 (-4.0A) | 0.50A | 4rv6A-1efyA:52.2 | 4rv6A-1efyA:86.57 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4RV6_B_RPBB1103_1 (POLY [ADP-RIBOSE]POLYMERASE 1) |
1efy | POLY (ADP-RIBOSE)POLYMERASE (Gallusgallus) | 5 / 11 | GLN A 763TYR A 896ALA A 898LYS A 903GLU A 988 | BZC A 201 (-3.8A)BZC A 201 (-4.0A)BZC A 201 ( 3.9A)BZC A 201 ( 4.8A)BZC A 201 (-4.0A) | 0.93A | 4rv6B-1efyA:52.4 | 4rv6B-1efyA:86.57 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4RV6_B_RPBB1103_1 (POLY [ADP-RIBOSE]POLYMERASE 1) |
1efy | POLY (ADP-RIBOSE)POLYMERASE (Gallusgallus) | 9 / 11 | HIS A 862GLY A 863TYR A 889TYR A 896ALA A 898LYS A 903SER A 904TYR A 907GLU A 988 | BZC A 201 (-4.0A)BZC A 201 (-3.9A)NoneBZC A 201 (-4.0A)BZC A 201 ( 3.9A)BZC A 201 ( 4.8A)BZC A 201 (-3.3A)BZC A 201 (-3.6A)BZC A 201 (-4.0A) | 0.49A | 4rv6B-1efyA:52.4 | 4rv6B-1efyA:86.57 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5HA9_B_TP0B406_1 (POLY [ADP-RIBOSE]POLYMERASE 1) |
1efy | POLY (ADP-RIBOSE)POLYMERASE (Gallusgallus) | 8 / 9 | ASP A 770HIS A 862SER A 864ASN A 868ILE A 872TYR A 896SER A 904TYR A 907 | NoneBZC A 201 (-4.0A)NoneNoneNoneBZC A 201 (-4.0A)BZC A 201 (-3.3A)BZC A 201 (-3.6A) | 0.55A | 5ha9B-1efyA:50.7 | 5ha9B-1efyA:86.86 |