SIMILAR PATTERN OF AMINO ACIDS MAPPED TO 'BYB'


List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZZQ_A_MTLA870_0
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 6eux POLYMERASE BASIC
PROTEIN 2
(Influenza
B
virus) 		4 / 8 GLN A 325
PHE A 327
ASN A 517
ASP A 518
 BYB  A 601 (-3.3A)
BYB  A 601 ( 4.4A)
None
None
 1.33A 1zzqA-6euxA:
undetectable		 1zzqA-6euxA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RQL_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 6eux POLYMERASE BASIC
PROTEIN 2
(Influenza
B
virus) 		4 / 8 PHE A 365
SER A 407
ARG A 334
TRP A 359
 None
None
BYB  A 601 ( 4.8A)
BYB  A 601 (-3.4A)
 1.37A 3rqlA-6euxA:
undetectable
3rqlB-6euxA:
undetectable		 3rqlA-6euxA:
11.42
3rqlB-6euxA:
11.42