SIMILAR PATTERN OF AMINO ACIDS MAPPED TO 'BWH'


List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DY4_A_SNPA437_2
(EXOGLUCANASE 1)		 6et8 -
(-) 		4 / 5 HIS A  78
TRP A  27
ALA A  53
TRP A  56
 BWH  A 301 (-4.1A)
BWH  A 301 (-3.6A)
None
None
 1.33A 1dy4A-6et8A:
undetectable		 1dy4A-6et8A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GMK_A_DVAA8_0
(GRAMICIDIN A)		 6et8 -
(-) 		3 / 4 VAL A 200
TRP A 162
TRP A 203
 None
BWH  A 301 (-4.5A)
None
 1.42A 1gmkA-6et8A:
undetectable
1gmkB-6et8A:
undetectable		 1gmkA-6et8A:
undetectable
1gmkB-6et8A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GMK_C_DVAC8_0
(GRAMICIDIN A)		 6et8 -
(-) 		3 / 4 VAL A 200
TRP A 162
TRP A 203
 None
BWH  A 301 (-4.5A)
None
 1.03A 1gmkC-6et8A:
undetectable
1gmkD-6et8A:
undetectable		 1gmkC-6et8A:
undetectable
1gmkD-6et8A:
undetectable