SIMILAR PATTERN OF AMINO ACIDS MAPPED TO 'BRN'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	2PNC_A_CLUA808_1 (COPPER AMINE OXIDASE, LIVER ISOZYME)	3hig	AMILORIDE-SENSITIVE AMINE OXIDASE (Homo sapiens)	6 / 7	ALA A 357 TYR A 359 TYR A 371 ASP A 373 TYR A 463 HIS A 512	TPQ A 461 ( 4.9A) None BRN A 901 (-3.3A) BRN A 901 (-3.3A) TPQ A 461 ( 4.5A) CU A 801 (-3.2A)	0.68A	2pncA-3higA: 46.1	2pncA-3higA: 40.08
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	2PNC_B_CLUB809_1 (COPPER AMINE OXIDASE, LIVER ISOZYME)	3hig	AMILORIDE-SENSITIVE AMINE OXIDASE (Homo sapiens)	5 / 6	ALA A 357 TYR A 371 ASP A 373 TYR A 463 HIS A 512	TPQ A 461 ( 4.9A) BRN A 901 (-3.3A) BRN A 901 (-3.3A) TPQ A 461 ( 4.5A) CU A 801 (-3.2A)	0.66A	2pncB-3higA: 50.4	2pncB-3higA: 40.08
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3HII_A_PNTA901_0 (AMILORIDE-SENSITIVE AMINE OXIDASE)	3hig	AMILORIDE-SENSITIVE AMINE OXIDASE (Homo sapiens)	12 / 12	TYR A 148 THR A 185 ASP A 186 TYR A 371 ASP A 373 TRP A 376 GLY A 377 SER A 380 VAL A 381 TYR A 404 TYR A 459 ASN A 460	BRN A 901 (-3.7A) BRN A 901 ( 4.2A) BRN A 901 (-3.9A) BRN A 901 (-3.3A) BRN A 901 (-3.3A) BRN A 901 (-3.5A) None None None None BRN A 901 (-3.2A) TPQ A 461 ( 3.3A)	0.38A	3hiiA-3higA: 67.6	3hiiA-3higA: 100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3HII_A_PNTA901_0 (AMILORIDE-SENSITIVE AMINE OXIDASE)	3hig	AMILORIDE-SENSITIVE AMINE OXIDASE (Homo sapiens)	6 / 12	TYR A 148 THR A 185 ASP A 373 GLY A 375 TYR A 459 ASN A 460	BRN A 901 (-3.7A) BRN A 901 ( 4.2A) BRN A 901 (-3.3A) None BRN A 901 (-3.2A) TPQ A 461 ( 3.3A)	1.42A	3hiiA-3higA: 67.6	3hiiA-3higA: 100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3HII_B_PNTB901_0 (AMILORIDE-SENSITIVE AMINE OXIDASE)	3hig	AMILORIDE-SENSITIVE AMINE OXIDASE (Homo sapiens)	12 / 12	TYR A 148 THR A 185 ASP A 186 TYR A 371 ASP A 373 TRP A 376 GLY A 377 SER A 380 VAL A 381 TYR A 404 TYR A 459 ASN A 460	BRN A 901 (-3.7A) BRN A 901 ( 4.2A) BRN A 901 (-3.9A) BRN A 901 (-3.3A) BRN A 901 (-3.3A) BRN A 901 (-3.5A) None None None None BRN A 901 (-3.2A) TPQ A 461 ( 3.3A)	0.36A	3hiiB-3higA: 62.8	3hiiB-3higA: 100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3HII_B_PNTB901_0 (AMILORIDE-SENSITIVE AMINE OXIDASE)	3hig	AMILORIDE-SENSITIVE AMINE OXIDASE (Homo sapiens)	6 / 12	TYR A 148 THR A 185 ASP A 373 GLY A 375 TYR A 459 ASN A 460	BRN A 901 (-3.7A) BRN A 901 ( 4.2A) BRN A 901 (-3.3A) None BRN A 901 (-3.2A) TPQ A 461 ( 3.3A)	1.45A	3hiiB-3higA: 62.8	3hiiB-3higA: 100.00

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["2PNC_A_CLUA808_1","COPPER AMINE OXIDASE, LIVER ISOZYME","3hig","AMILORIDE-SENSITIVE AMINE OXIDASE","Homo sapiens",6,"ALA A 357;TYR A 359;TYR A 371;ASP A 373;TYR A 463;HIS A 512","TPQ A 461 ( 4.9A);None;BRN A 901 (-3.3A);BRN A 901 (-3.3A);TPQ A 461 ( 4.5A); CU A 801 (-3.2A)","0.68A","2pncA-3higA:46.1",null],["2PNC_B_CLUB809_1","COPPER AMINE OXIDASE, LIVER ISOZYME","3hig","AMILORIDE-SENSITIVE AMINE OXIDASE","Homo sapiens",5,"ALA A 357;TYR A 371;ASP A 373;TYR A 463;HIS A 512","TPQ A 461 ( 4.9A);BRN A 901 (-3.3A);BRN A 901 (-3.3A);TPQ A 461 ( 4.5A); CU A 801 (-3.2A)","0.66A","2pncB-3higA:50.4","2pncA-3higA:40.08"],["3HII_A_PNTA901_0","AMILORIDE-SENSITIVE AMINE OXIDASE","3hig","AMILORIDE-SENSITIVE AMINE OXIDASE","Homo sapiens",12,"TYR A 148;THR A 185;ASP A 186;TYR A 371;ASP A 373;TRP A 376;GLY A 377;SER A 380;VAL A 381;TYR A 404;TYR A 459;ASN A 460","BRN A 901 (-3.7A);BRN A 901 ( 4.2A);BRN A 901 (-3.9A);BRN A 901 (-3.3A);BRN A 901 (-3.3A);BRN A 901 (-3.5A);None;None;None;None;BRN A 901 (-3.2A);TPQ A 461 ( 3.3A)","0.38A","3hiiA-3higA:67.6","2pncB-3higA:40.08"],["3HII_A_PNTA901_0","AMILORIDE-SENSITIVE AMINE OXIDASE","3hig","AMILORIDE-SENSITIVE AMINE OXIDASE","Homo sapiens",6,"TYR A 148;THR A 185;ASP A 373;GLY A 375;TYR A 459;ASN A 460","BRN A 901 (-3.7A);BRN A 901 ( 4.2A);BRN A 901 (-3.3A);None;BRN A 901 (-3.2A);TPQ A 461 ( 3.3A)","1.42A","3hiiA-3higA:67.6","3hiiA-3higA:100.00"],["3HII_B_PNTB901_0","AMILORIDE-SENSITIVE AMINE OXIDASE","3hig","AMILORIDE-SENSITIVE AMINE OXIDASE","Homo sapiens",12,"TYR A 148;THR A 185;ASP A 186;TYR A 371;ASP A 373;TRP A 376;GLY A 377;SER A 380;VAL A 381;TYR A 404;TYR A 459;ASN A 460","BRN A 901 (-3.7A);BRN A 901 ( 4.2A);BRN A 901 (-3.9A);BRN A 901 (-3.3A);BRN A 901 (-3.3A);BRN A 901 (-3.5A);None;None;None;None;BRN A 901 (-3.2A);TPQ A 461 ( 3.3A)","0.36A","3hiiB-3higA:62.8","3hiiA-3higA:100.00"],["3HII_B_PNTB901_0","AMILORIDE-SENSITIVE AMINE OXIDASE","3hig","AMILORIDE-SENSITIVE AMINE OXIDASE","Homo sapiens",6,"TYR A 148;THR A 185;ASP A 373;GLY A 375;TYR A 459;ASN A 460","BRN A 901 (-3.7A);BRN A 901 ( 4.2A);BRN A 901 (-3.3A);None;BRN A 901 (-3.2A);TPQ A 461 ( 3.3A)","1.45A","3hiiB-3higA:62.8","3hiiB-3higA:100.00"]]