SIMILAR PATTERN OF AMINO ACIDS MAPPED TO 'BRD'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2O4L_A_TPVA403_2 (PROTEASE)	1mq0	CYTIDINE DEAMINASE (Homo sapiens)	5 / 12	ALA A 70 GLY A 39 VAL A 38 VAL A 115 ILE A 85	None None BRD A 148 (-4.2A) None None	0.89A	2o4lB-1mq0A: undetectable	2o4lB-1mq0A: 20.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3CYX_A_ROCA201_3 (HIV-1 PROTEASE)	1mq0	CYTIDINE DEAMINASE (Homo sapiens)	5 / 12	ARG A 103 GLY A 39 VAL A 38 VAL A 115 ILE A 85	None None BRD A 148 (-4.2A) None None	0.85A	3cyxB-1mq0A: undetectable	3cyxB-1mq0A: 21.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3OXX_A_DR7A100_2 (HIV-1 PROTEASE)	1mq0	CYTIDINE DEAMINASE (Homo sapiens)	5 / 11	ARG A 103 GLY A 39 VAL A 38 VAL A 115 ILE A 85	None None BRD A 148 (-4.2A) None None	0.78A	3oxxB-1mq0A: undetectable	3oxxB-1mq0A: 21.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3OXX_C_DR7C100_2 (HIV-1 PROTEASE)	1mq0	CYTIDINE DEAMINASE (Homo sapiens)	5 / 11	ARG A 103 GLY A 39 VAL A 38 VAL A 115 ILE A 85	None None BRD A 148 (-4.2A) None None	0.82A	3oxxD-1mq0A: undetectable	3oxxD-1mq0A: 21.90

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["2O4L_A_TPVA403_2","PROTEASE;PROTEASE","1mq0","CYTIDINE DEAMINASE","Homo sapiens",5,"ALA A  70;GLY A  39;VAL A  38;VAL A 115;ILE A  85","None;None;BRD A 148 (-4.2A);None;None","0.89A","2o4lB-1mq0A:undetectable",null],["3CYX_A_ROCA201_3","HIV-1 PROTEASE;HIV-1 PROTEASE","1mq0","CYTIDINE DEAMINASE","Homo sapiens",5,"ARG A 103;GLY A  39;VAL A  38;VAL A 115;ILE A  85","None;None;BRD A 148 (-4.2A);None;None","0.85A","3cyxB-1mq0A:undetectable","2o4lB-1mq0A:20.86"],["3OXX_A_DR7A100_2","HIV-1 PROTEASE;HIV-1 PROTEASE","1mq0","CYTIDINE DEAMINASE","Homo sapiens",5,"ARG A 103;GLY A  39;VAL A  38;VAL A 115;ILE A  85","None;None;BRD A 148 (-4.2A);None;None","0.78A","3oxxB-1mq0A:undetectable","3cyxB-1mq0A:21.17"],["3OXX_C_DR7C100_2","HIV-1 PROTEASE;HIV-1 PROTEASE","1mq0","CYTIDINE DEAMINASE","Homo sapiens",5,"ARG A 103;GLY A  39;VAL A  38;VAL A 115;ILE A  85","None;None;BRD A 148 (-4.2A);None;None","0.82A","3oxxD-1mq0A:undetectable","3oxxB-1mq0A:21.90"]]