SIMILAR PATTERN OF AMINO ACIDS MAPPED TO 'BR7'


List of Similar Pattern of Amino Acids


Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3RQW_A_ACHA323_0
(ELIC PENTAMERIC
LIGAND GATED ION
CHANNEL FROM ERWINIA
CHRYSANTHEMI)
4twf CYS-LOOP
LIGAND-GATED ION
CHANNEL

(Dickeya
chrysanthemi)
5 / 9 GLU A  77
ILE A  79
GLU A 131
TYR A 175
PHE A 188
BR7  A 401 ( 4.9A)
None
BR7  A 401 (-4.1A)
BR7  A 401 (-3.9A)
BR7  A 401 (-3.9A)
0.70A 3rqwA-4twfA:
33.0
3rqwB-4twfA:
33.0
3rqwA-4twfA:
99.35
3rqwB-4twfA:
99.35
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3RQW_B_ACHB323_0
(ELIC PENTAMERIC
LIGAND GATED ION
CHANNEL FROM ERWINIA
CHRYSANTHEMI)
4twf CYS-LOOP
LIGAND-GATED ION
CHANNEL

(Dickeya
chrysanthemi)
5 / 9 GLU A  77
ILE A  79
GLU A 131
TYR A 175
PHE A 188
BR7  A 401 ( 4.9A)
None
BR7  A 401 (-4.1A)
BR7  A 401 (-3.9A)
BR7  A 401 (-3.9A)
0.68A 3rqwB-4twfA:
33.0
3rqwC-4twfA:
33.0
3rqwB-4twfA:
99.35
3rqwC-4twfA:
99.35
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3RQW_C_ACHC323_0
(ELIC PENTAMERIC
LIGAND GATED ION
CHANNEL FROM ERWINIA
CHRYSANTHEMI)
4twf CYS-LOOP
LIGAND-GATED ION
CHANNEL

(Dickeya
chrysanthemi)
4 / 8 GLU A  77
GLU A 131
TYR A 175
PHE A 188
BR7  A 401 ( 4.9A)
BR7  A 401 (-4.1A)
BR7  A 401 (-3.9A)
BR7  A 401 (-3.9A)
0.67A 3rqwC-4twfA:
33.0
3rqwD-4twfA:
33.0
3rqwC-4twfA:
99.35
3rqwD-4twfA:
99.35
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3RQW_D_ACHD323_0
(ELIC PENTAMERIC
LIGAND GATED ION
CHANNEL FROM ERWINIA
CHRYSANTHEMI)
4twf CYS-LOOP
LIGAND-GATED ION
CHANNEL

(Dickeya
chrysanthemi)
5 / 9 GLU A  77
ILE A  79
GLU A 131
TYR A 175
PHE A 188
BR7  A 401 ( 4.9A)
None
BR7  A 401 (-4.1A)
BR7  A 401 (-3.9A)
BR7  A 401 (-3.9A)
0.67A 3rqwD-4twfA:
33.0
3rqwE-4twfA:
33.0
3rqwD-4twfA:
99.35
3rqwE-4twfA:
99.35
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3RQW_E_ACHE323_0
(ELIC PENTAMERIC
LIGAND GATED ION
CHANNEL FROM ERWINIA
CHRYSANTHEMI)
4twf CYS-LOOP
LIGAND-GATED ION
CHANNEL

(Dickeya
chrysanthemi)
5 / 9 GLU A  77
ILE A  79
GLU A 131
TYR A 175
PHE A 188
BR7  A 401 ( 4.9A)
None
BR7  A 401 (-4.1A)
BR7  A 401 (-3.9A)
BR7  A 401 (-3.9A)
0.67A 3rqwA-4twfA:
33.0
3rqwE-4twfA:
33.0
3rqwA-4twfA:
99.35
3rqwE-4twfA:
99.35
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3RQW_F_ACHF323_0
(ELIC PENTAMERIC
LIGAND GATED ION
CHANNEL FROM ERWINIA
CHRYSANTHEMI)
4twf CYS-LOOP
LIGAND-GATED ION
CHANNEL

(Dickeya
chrysanthemi)
5 / 9 GLU A  77
ILE A  79
GLU A 131
TYR A 175
PHE A 188
BR7  A 401 ( 4.9A)
None
BR7  A 401 (-4.1A)
BR7  A 401 (-3.9A)
BR7  A 401 (-3.9A)
0.68A 3rqwF-4twfA:
33.0
3rqwG-4twfA:
33.0
3rqwF-4twfA:
99.35
3rqwG-4twfA:
99.35
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3RQW_G_ACHG323_0
(ELIC PENTAMERIC
LIGAND GATED ION
CHANNEL FROM ERWINIA
CHRYSANTHEMI)
4twf CYS-LOOP
LIGAND-GATED ION
CHANNEL

(Dickeya
chrysanthemi)
5 / 9 GLU A  77
ILE A  79
GLU A 131
TYR A 175
PHE A 188
BR7  A 401 ( 4.9A)
None
BR7  A 401 (-4.1A)
BR7  A 401 (-3.9A)
BR7  A 401 (-3.9A)
0.67A 3rqwG-4twfA:
33.0
3rqwH-4twfA:
33.0
3rqwG-4twfA:
99.35
3rqwH-4twfA:
99.35
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3RQW_H_ACHH323_0
(ELIC PENTAMERIC
LIGAND GATED ION
CHANNEL FROM ERWINIA
CHRYSANTHEMI)
4twf CYS-LOOP
LIGAND-GATED ION
CHANNEL

(Dickeya
chrysanthemi)
5 / 9 GLU A  77
ILE A  79
GLU A 131
TYR A 175
PHE A 188
BR7  A 401 ( 4.9A)
None
BR7  A 401 (-4.1A)
BR7  A 401 (-3.9A)
BR7  A 401 (-3.9A)
0.66A 3rqwH-4twfA:
33.0
3rqwI-4twfA:
33.0
3rqwH-4twfA:
99.35
3rqwI-4twfA:
99.35
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3RQW_I_ACHI323_0
(ELIC PENTAMERIC
LIGAND GATED ION
CHANNEL FROM ERWINIA
CHRYSANTHEMI)
4twf CYS-LOOP
LIGAND-GATED ION
CHANNEL

(Dickeya
chrysanthemi)
4 / 8 ILE A  79
GLU A 131
TYR A 175
PHE A 188
None
BR7  A 401 (-4.1A)
BR7  A 401 (-3.9A)
BR7  A 401 (-3.9A)
0.60A 3rqwI-4twfA:
33.0
3rqwJ-4twfA:
33.0
3rqwI-4twfA:
99.35
3rqwJ-4twfA:
99.35
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3RQW_J_ACHJ323_0
(ELIC PENTAMERIC
LIGAND GATED ION
CHANNEL FROM ERWINIA
CHRYSANTHEMI)
4twf CYS-LOOP
LIGAND-GATED ION
CHANNEL

(Dickeya
chrysanthemi)
4 / 8 GLU A  77
GLU A 131
TYR A 175
PHE A 188
BR7  A 401 ( 4.9A)
BR7  A 401 (-4.1A)
BR7  A 401 (-3.9A)
BR7  A 401 (-3.9A)
0.68A 3rqwF-4twfA:
33.0
3rqwJ-4twfA:
33.0
3rqwF-4twfA:
99.35
3rqwJ-4twfA:
99.35
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4A97_A_ZPCA1318_1
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)
4twf CYS-LOOP
LIGAND-GATED ION
CHANNEL

(Dickeya
chrysanthemi)
5 / 7 GLU A  77
ILE A  79
GLU A 131
PHE A 133
TYR A 175
BR7  A 401 ( 4.9A)
None
BR7  A 401 (-4.1A)
BR7  A 401 (-4.5A)
BR7  A 401 (-3.9A)
0.40A 4a97A-4twfA:
33.7
4a97A-4twfA:
99.35
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4A97_A_ZPCA1318_1
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)
4twf CYS-LOOP
LIGAND-GATED ION
CHANNEL

(Dickeya
chrysanthemi)
4 / 7 ILE A  79
GLU A 131
TYR A 175
VAL A 181
None
BR7  A 401 (-4.1A)
BR7  A 401 (-3.9A)
None
1.10A 4a97A-4twfA:
33.7
4a97A-4twfA:
99.35
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4A97_D_ZPCD1318_2
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)
4twf CYS-LOOP
LIGAND-GATED ION
CHANNEL

(Dickeya
chrysanthemi)
5 / 7 GLU A  77
ILE A  79
GLU A 131
PHE A 133
TYR A 175
BR7  A 401 ( 4.9A)
None
BR7  A 401 (-4.1A)
BR7  A 401 (-4.5A)
BR7  A 401 (-3.9A)
0.54A 4a97D-4twfA:
33.6
4a97D-4twfA:
99.35
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4A97_E_ZPCE1318_2
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)
4twf CYS-LOOP
LIGAND-GATED ION
CHANNEL

(Dickeya
chrysanthemi)
4 / 6 GLU A 131
PHE A 133
TYR A 175
PHE A 188
BR7  A 401 (-4.1A)
BR7  A 401 (-4.5A)
BR7  A 401 (-3.9A)
BR7  A 401 (-3.9A)
0.55A 4a97E-4twfA:
33.7
4a97E-4twfA:
99.35
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4A97_H_ZPCH1318_2
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)
4twf CYS-LOOP
LIGAND-GATED ION
CHANNEL

(Dickeya
chrysanthemi)
5 / 7 GLU A  77
ILE A  79
GLU A 131
TYR A 175
PHE A 188
BR7  A 401 ( 4.9A)
None
BR7  A 401 (-4.1A)
BR7  A 401 (-3.9A)
BR7  A 401 (-3.9A)
0.45A 4a97H-4twfA:
33.9
4a97H-4twfA:
99.35
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4A97_H_ZPCH1318_2
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)
4twf CYS-LOOP
LIGAND-GATED ION
CHANNEL

(Dickeya
chrysanthemi)
4 / 7 GLU A 131
TYR A 175
VAL A 181
PHE A 188
BR7  A 401 (-4.1A)
BR7  A 401 (-3.9A)
None
BR7  A 401 (-3.9A)
1.06A 4a97H-4twfA:
33.9
4a97H-4twfA:
99.35
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4A97_I_ZPCI1318_2
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)
4twf CYS-LOOP
LIGAND-GATED ION
CHANNEL

(Dickeya
chrysanthemi)
4 / 6 GLU A  77
ILE A  79
PHE A 133
TYR A 175
BR7  A 401 ( 4.9A)
None
BR7  A 401 (-4.5A)
BR7  A 401 (-3.9A)
0.49A 4a97I-4twfA:
33.9
4a97I-4twfA:
99.35
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4A97_J_ZPCJ1318_2
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)
4twf CYS-LOOP
LIGAND-GATED ION
CHANNEL

(Dickeya
chrysanthemi)
4 / 5 GLU A  77
GLU A 131
PHE A 133
TYR A 175
BR7  A 401 ( 4.9A)
BR7  A 401 (-4.1A)
BR7  A 401 (-4.5A)
BR7  A 401 (-3.9A)
0.57A 4a97J-4twfA:
33.7
4a97J-4twfA:
99.35
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4TWD_A_377A401_1
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)
4twf CYS-LOOP
LIGAND-GATED ION
CHANNEL

(Dickeya
chrysanthemi)
4 / 5 GLU A  77
GLU A 131
TYR A 175
PHE A 188
BR7  A 401 ( 4.9A)
BR7  A 401 (-4.1A)
BR7  A 401 (-3.9A)
BR7  A 401 (-3.9A)
0.32A 4twdA-4twfA:
34.7
4twdE-4twfA:
34.1
4twdA-4twfA:
100.00
4twdE-4twfA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4TWD_B_377B401_1
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)
4twf CYS-LOOP
LIGAND-GATED ION
CHANNEL

(Dickeya
chrysanthemi)
4 / 5 GLU A  77
GLU A 131
TYR A 175
PHE A 188
BR7  A 401 ( 4.9A)
BR7  A 401 (-4.1A)
BR7  A 401 (-3.9A)
BR7  A 401 (-3.9A)
0.34A 4twdA-4twfA:
34.7
4twdB-4twfA:
34.0
4twdA-4twfA:
100.00
4twdB-4twfA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4TWD_F_377F401_1
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)
4twf CYS-LOOP
LIGAND-GATED ION
CHANNEL

(Dickeya
chrysanthemi)
4 / 7 GLU A  77
GLU A 131
TYR A 175
PHE A 188
BR7  A 401 ( 4.9A)
BR7  A 401 (-4.1A)
BR7  A 401 (-3.9A)
BR7  A 401 (-3.9A)
0.31A 4twdF-4twfA:
34.3
4twdJ-4twfA:
33.8
4twdF-4twfA:
100.00
4twdJ-4twfA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4TWD_H_377H401_1
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)
4twf CYS-LOOP
LIGAND-GATED ION
CHANNEL

(Dickeya
chrysanthemi)
4 / 6 GLU A  77
GLU A 131
TYR A 175
PHE A 188
BR7  A 401 ( 4.9A)
BR7  A 401 (-4.1A)
BR7  A 401 (-3.9A)
BR7  A 401 (-3.9A)
0.39A 4twdG-4twfA:
34.0
4twdH-4twfA:
34.3
4twdG-4twfA:
100.00
4twdH-4twfA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4TWD_H_377H402_1
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)
4twf CYS-LOOP
LIGAND-GATED ION
CHANNEL

(Dickeya
chrysanthemi)
4 / 5 GLU A  77
GLU A 131
TYR A 175
PHE A 188
BR7  A 401 ( 4.9A)
BR7  A 401 (-4.1A)
BR7  A 401 (-3.9A)
BR7  A 401 (-3.9A)
0.35A 4twdH-4twfA:
34.3
4twdI-4twfA:
34.0
4twdH-4twfA:
100.00
4twdI-4twfA:
100.00