SIMILAR PATTERN OF AMINO ACIDS MAPPED TO 'BQZ'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2YA7_C_ZMRC1776_1 (NEURAMINIDASE A)	6eq8	PERIPLASMIC ALPHA-GALACTOSIDE-BI NDING PROTEIN (Agrobacterium tumefaciens)	5 / 12	ASP D 114 ILE D 115 ASP D 642 PHE D 331 LEU D 619	BQZ D 708 ( 4.8A) None None None None	1.42A	2ya7C-6eq8D: undetectable	2ya7C-6eq8D: 9.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5G5G_A_ACTA1231_0 (PUTATIVE XANTHINE DEHYDROGENASE YAGR MOLYBDENUM-BINDING SU SUBUNIT PUTATIVE XANTHINE DEHYDROGENASE YAGT IRON-SULFUR-BINDING SUBUNIT)	6eq8	PERIPLASMIC ALPHA-GALACTOSIDE-BI NDING PROTEIN (Agrobacterium tumefaciens)	3 / 3	ARG D 533 THR D 489 ASP D 490	BQZ D 708 (-3.3A) None None	0.90A	5g5gA-6eq8D: undetectable 5g5gB-6eq8D: undetectable	5g5gA-6eq8D: undetectable 5g5gB-6eq8D: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6CDU_A_EY4A502_0 (CHIMERIC ALPHA1GABAA RECEPTOR)	6eq8	PERIPLASMIC ALPHA-GALACTOSIDE-BI NDING PROTEIN (Agrobacterium tumefaciens)	4 / 7	THR D 489 TYR D 487 GLN D 368 VAL D 531	None BQZ D 708 (-4.5A) None None	0.54A	6cduA-6eq8D: undetectable 6cduE-6eq8D: undetectable	6cduA-6eq8D: undetectable 6cduE-6eq8D: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6CDU_H_EY4H500_0 (CHIMERIC ALPHA1GABAA RECEPTOR)	6eq8	PERIPLASMIC ALPHA-GALACTOSIDE-BI NDING PROTEIN (Agrobacterium tumefaciens)	4 / 7	GLN D 368 VAL D 531 THR D 489 TYR D 487	None None None BQZ D 708 (-4.5A)	0.59A	6cduH-6eq8D: undetectable 6cduI-6eq8D: undetectable	6cduH-6eq8D: undetectable 6cduI-6eq8D: undetectable

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["2YA7_C_ZMRC1776_1","NEURAMINIDASE A","6eq8","PERIPLASMIC ALPHA-GALACTOSIDE-BINDING PROTEIN","Agrobacterium tumefaciens",5,"ASP D 114;ILE D 115;ASP D 642;PHE D 331;LEU D 619","BQZ D 708 ( 4.8A);None;None;None;None","1.42A","2ya7C-6eq8D:undetectable",null],["5G5G_A_ACTA1231_0","PUTATIVE XANTHINE DEHYDROGENASE YAGR MOLYBDENUM-BINDING SU SUBUNIT;PUTATIVE XANTHINE DEHYDROGENASE YAGT IRON-SULFUR-BINDING SUBUNIT","6eq8","PERIPLASMIC ALPHA-GALACTOSIDE-BINDING PROTEIN","Agrobacterium tumefaciens",3,"ARG D 533;THR D 489;ASP D 490","BQZ D 708 (-3.3A);None;None","0.90A","5g5gA-6eq8D:undetectable;5g5gB-6eq8D:undetectable","2ya7C-6eq8D:9.51"],["6CDU_A_EY4A502_0","CHIMERIC ALPHA1GABAA RECEPTOR","6eq8","PERIPLASMIC ALPHA-GALACTOSIDE-BINDING PROTEIN","Agrobacterium tumefaciens",4,"THR D 489;TYR D 487;GLN D 368;VAL D 531","None;BQZ D 708 (-4.5A);None;None","0.54A","6cduA-6eq8D:undetectable;6cduE-6eq8D:undetectable","5g5gA-6eq8D:undetectable;5g5gB-6eq8D:undetectable"],["6CDU_H_EY4H500_0","CHIMERIC ALPHA1GABAA RECEPTOR","6eq8","PERIPLASMIC ALPHA-GALACTOSIDE-BINDING PROTEIN","Agrobacterium tumefaciens",4,"GLN D 368;VAL D 531;THR D 489;TYR D 487","None;None;None;BQZ D 708 (-4.5A)","0.59A","6cduH-6eq8D:undetectable;6cduI-6eq8D:undetectable","6cduA-6eq8D:undetectable;6cduE-6eq8D:undetectable"]]