SIMILAR PATTERN OF AMINO ACIDS MAPPED TO 'BQR'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1HK1_A_T44A3003_1 (SERUM ALBUMIN)	5c4g	PHOSPHATIDYLINOSITOL 4-KINASE BETA (Homo sapiens)	4 / 6	HIS E 672 ILE E 671 ALA E 666 VAL E 598	None None None BQR E 803 (-3.8A)	1.05A	1hk1A-5c4gE: undetectable	1hk1A-5c4gE: 21.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3OZU_A_X89A411_1 (FLAVOHEMOPROTEIN)	5c4g	PHOSPHATIDYLINOSITOL 4-KINASE BETA (Homo sapiens)	5 / 12	ALA E 357 LEU E 354 LEU E 317 ALA E 371 LEU E 383	None None None None BQR E 803 ( 4.3A)	1.15A	3ozuA-5c4gE: undetectable	3ozuA-5c4gE: 22.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3OZU_A_X89A411_1 (FLAVOHEMOPROTEIN)	5c4g	PHOSPHATIDYLINOSITOL 4-KINASE BETA (Homo sapiens)	5 / 12	LEU E 354 VAL E 386 LEU E 317 ALA E 371 LEU E 383	None None None None BQR E 803 ( 4.3A)	1.30A	3ozuA-5c4gE: undetectable	3ozuA-5c4gE: 22.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4XE0_A_40LA1101_0 (PHOSPHATIDYLINOSITOL 4,5-BISPHOSPHATE 3-KINASE CATALYTIC SUBUNIT DELTA ISOFORM)	5c4g	PHOSPHATIDYLINOSITOL 4-KINASE BETA (Homo sapiens)	5 / 12	PRO E 381 ILE E 547 TYR E 583 VAL E 598 ILE E 673	BQR E 803 ( 4.7A) BQR E 803 ( 4.7A) BQR E 803 ( 3.0A) BQR E 803 (-3.8A) BQR E 803 ( 3.9A)	0.63A	4xe0A-5c4gE: 15.6	4xe0A-5c4gE: 21.08

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1HK1_A_T44A3003_1","SERUM ALBUMIN","5c4g","PHOSPHATIDYLINOSITOL 4-KINASE BETA","Homo sapiens",4,"HIS E 672;ILE E 671;ALA E 666;VAL E 598","None;None;None;BQR E 803 (-3.8A)","1.05A","1hk1A-5c4gE:undetectable",null],["3OZU_A_X89A411_1","FLAVOHEMOPROTEIN","5c4g","PHOSPHATIDYLINOSITOL 4-KINASE BETA","Homo sapiens",5,"ALA E 357;LEU E 354;LEU E 317;ALA E 371;LEU E 383","None;None;None;None;BQR E 803 ( 4.3A)","1.15A","3ozuA-5c4gE:undetectable","1hk1A-5c4gE:21.75"],["3OZU_A_X89A411_1","FLAVOHEMOPROTEIN","5c4g","PHOSPHATIDYLINOSITOL 4-KINASE BETA","Homo sapiens",5,"LEU E 354;VAL E 386;LEU E 317;ALA E 371;LEU E 383","None;None;None;None;BQR E 803 ( 4.3A)","1.30A","3ozuA-5c4gE:undetectable","3ozuA-5c4gE:22.12"],["4XE0_A_40LA1101_0","PHOSPHATIDYLINOSITOL 4,5-BISPHOSPHATE 3-KINASE CATALYTIC SUBUNIT DELTA ISOFORM","5c4g","PHOSPHATIDYLINOSITOL 4-KINASE BETA","Homo sapiens",5,"PRO E 381;ILE E 547;TYR E 583;VAL E 598;ILE E 673","BQR E 803 ( 4.7A);BQR E 803 ( 4.7A);BQR E 803 ( 3.0A);BQR E 803 (-3.8A);BQR E 803 ( 3.9A)","0.63A","4xe0A-5c4gE:15.6","3ozuA-5c4gE:22.12"]]