SIMILAR PATTERN OF AMINO ACIDS MAPPED TO 'BP7'


List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TMX_A_BEZA881_0
(HYDROXYQUINOL
1,2-DIOXYGENASE)		 2ei0 1,2-DIHYDROXYNAPHTHA
LENE DIOXYGENASE
(Pseudomonas
sp.
C18) 		5 / 11 LEU A  31
GLY A 268
PRO A 267
TYR A 256
HIS A 152
 None
None
None
BP7  A 400 ( 4.7A)
FE2  A 399 ( 3.4A)
 1.37A 1tmxA-2ei0A:
undetectable		 1tmxA-2ei0A:
23.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZWE_B_DAHB98_1
(TYROSINASE
MELC)		 2ei0 1,2-DIHYDROXYNAPHTHA
LENE DIOXYGENASE
(Pseudomonas
sp.
C18) 		5 / 11 HIS A 215
ILE A 154
HIS A 152
ASN A 249
HIS A 247
 FE2  A 399 ( 3.3A)
BP7  A 401 (-4.3A)
FE2  A 399 ( 3.4A)
BP7  A 400 (-3.3A)
BP7  A 400 (-3.2A)
 1.43A 2zweA-2ei0A:
undetectable
2zweB-2ei0A:
undetectable		 2zweA-2ei0A:
22.66
2zweB-2ei0A:
15.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZWE_B_DAHB98_1
(TYROSINASE
MELC)		 2ei0 1,2-DIHYDROXYNAPHTHA
LENE DIOXYGENASE
(Pseudomonas
sp.
C18) 		5 / 11 HIS A 215
ILE A 154
HIS A 152
HIS A 247
ASN A 249
 FE2  A 399 ( 3.3A)
BP7  A 401 (-4.3A)
FE2  A 399 ( 3.4A)
BP7  A 400 (-3.2A)
BP7  A 400 (-3.3A)
 1.33A 2zweA-2ei0A:
undetectable
2zweB-2ei0A:
undetectable		 2zweA-2ei0A:
22.66
2zweB-2ei0A:
15.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AVO_A_PAUA314_0
(PANTOTHENATE KINASE)		 2ei0 1,2-DIHYDROXYNAPHTHA
LENE DIOXYGENASE
(Pseudomonas
sp.
C18) 		5 / 11 LEU A 242
TYR A 256
HIS A 215
PHE A 192
ILE A 180
 None
BP7  A 400 ( 4.7A)
FE2  A 399 ( 3.3A)
BP7  A 401 ( 4.1A)
BP7  A 400 ( 4.9A)
 1.23A 3avoA-2ei0A:
0.0		 3avoA-2ei0A:
22.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BLV_A_SAMA1281_1
(RIBOSOMAL RNA LARGE
SUBUNIT
METHYLTRANSFERASE J)		 2ei0 1,2-DIHYDROXYNAPHTHA
LENE DIOXYGENASE
(Pseudomonas
sp.
C18) 		4 / 6 HIS A 247
HIS A 215
GLU A 177
ASP A 276
 BP7  A 400 (-3.2A)
FE2  A 399 ( 3.3A)
MG  A 398 (-2.5A)
BP7  A 402 (-2.7A)
 1.03A 4blvA-2ei0A:
undetectable		 4blvA-2ei0A:
20.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IR0_A_FCNA202_1
(METALLOTHIOL
TRANSFERASE FOSB 2)		 2ei0 1,2-DIHYDROXYNAPHTHA
LENE DIOXYGENASE
(Pseudomonas
sp.
C18) 		5 / 11 HIS A 215
TYR A 256
GLU A 266
HIS A 152
ALA A 203
 FE2  A 399 ( 3.3A)
BP7  A 400 ( 4.7A)
FE2  A 399 ( 2.5A)
FE2  A 399 ( 3.4A)
BP7  A 401 ( 3.9A)
 0.60A 4ir0A-2ei0A:
7.8
4ir0B-2ei0A:
8.2		 4ir0A-2ei0A:
20.68
4ir0B-2ei0A:
20.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IR0_B_FCNB202_1
(METALLOTHIOL
TRANSFERASE FOSB 2)		 2ei0 1,2-DIHYDROXYNAPHTHA
LENE DIOXYGENASE
(Pseudomonas
sp.
C18) 		5 / 11 HIS A 152
ALA A 203
HIS A 215
TYR A 256
GLU A 266
 FE2  A 399 ( 3.4A)
BP7  A 401 ( 3.9A)
FE2  A 399 ( 3.3A)
BP7  A 400 ( 4.7A)
FE2  A 399 ( 2.5A)
 0.53A 4ir0A-2ei0A:
7.8
4ir0B-2ei0A:
8.2		 4ir0A-2ei0A:
20.68
4ir0B-2ei0A:
20.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JD1_A_FCNA202_1
(METALLOTHIOL
TRANSFERASE FOSB 2)		 2ei0 1,2-DIHYDROXYNAPHTHA
LENE DIOXYGENASE
(Pseudomonas
sp.
C18) 		5 / 12 HIS A 215
TYR A 256
GLU A 266
HIS A 152
ALA A 203
 FE2  A 399 ( 3.3A)
BP7  A 400 ( 4.7A)
FE2  A 399 ( 2.5A)
FE2  A 399 ( 3.4A)
BP7  A 401 ( 3.9A)
 0.54A 4jd1A-2ei0A:
7.9
4jd1B-2ei0A:
7.9		 4jd1A-2ei0A:
20.68
4jd1B-2ei0A:
20.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JD1_B_FCNB203_1
(METALLOTHIOL
TRANSFERASE FOSB 2)		 2ei0 1,2-DIHYDROXYNAPHTHA
LENE DIOXYGENASE
(Pseudomonas
sp.
C18) 		5 / 12 HIS A 152
ALA A 203
HIS A 215
TYR A 256
GLU A 266
 FE2  A 399 ( 3.4A)
BP7  A 401 ( 3.9A)
FE2  A 399 ( 3.3A)
BP7  A 400 ( 4.7A)
FE2  A 399 ( 2.5A)
 0.65A 4jd1A-2ei0A:
7.9
4jd1B-2ei0A:
7.9		 4jd1A-2ei0A:
20.68
4jd1B-2ei0A:
20.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JH3_A_FCNA204_1
(METALLOTHIOL
TRANSFERASE FOSB)		 2ei0 1,2-DIHYDROXYNAPHTHA
LENE DIOXYGENASE
(Pseudomonas
sp.
C18) 		5 / 12 HIS A 215
TYR A 256
GLU A 266
HIS A 152
ALA A 203
 FE2  A 399 ( 3.3A)
BP7  A 400 ( 4.7A)
FE2  A 399 ( 2.5A)
FE2  A 399 ( 3.4A)
BP7  A 401 ( 3.9A)
 0.51A 4jh3A-2ei0A:
7.5
4jh3B-2ei0A:
7.6		 4jh3A-2ei0A:
19.47
4jh3B-2ei0A:
19.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JH3_B_FCNB203_1
(METALLOTHIOL
TRANSFERASE FOSB)		 2ei0 1,2-DIHYDROXYNAPHTHA
LENE DIOXYGENASE
(Pseudomonas
sp.
C18) 		5 / 11 HIS A 152
ALA A 203
HIS A 215
TYR A 256
GLU A 266
 FE2  A 399 ( 3.4A)
BP7  A 401 ( 3.9A)
FE2  A 399 ( 3.3A)
BP7  A 400 ( 4.7A)
FE2  A 399 ( 2.5A)
 0.49A 4jh3A-2ei0A:
7.5
4jh3B-2ei0A:
7.6		 4jh3A-2ei0A:
19.47
4jh3B-2ei0A:
19.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JH4_A_FCNA202_1
(METALLOTHIOL
TRANSFERASE FOSB)		 2ei0 1,2-DIHYDROXYNAPHTHA
LENE DIOXYGENASE
(Pseudomonas
sp.
C18) 		5 / 11 HIS A 215
TYR A 256
GLU A 266
HIS A 152
ALA A 203
 FE2  A 399 ( 3.3A)
BP7  A 400 ( 4.7A)
FE2  A 399 ( 2.5A)
FE2  A 399 ( 3.4A)
BP7  A 401 ( 3.9A)
 0.47A 4jh4A-2ei0A:
7.5
4jh4B-2ei0A:
7.5		 4jh4A-2ei0A:
19.47
4jh4B-2ei0A:
19.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JH4_B_FCNB202_1
(METALLOTHIOL
TRANSFERASE FOSB)		 2ei0 1,2-DIHYDROXYNAPHTHA
LENE DIOXYGENASE
(Pseudomonas
sp.
C18) 		5 / 11 HIS A 152
ALA A 203
HIS A 215
TYR A 256
GLU A 266
 FE2  A 399 ( 3.4A)
BP7  A 401 ( 3.9A)
FE2  A 399 ( 3.3A)
BP7  A 400 ( 4.7A)
FE2  A 399 ( 2.5A)
 0.48A 4jh4A-2ei0A:
7.5
4jh4B-2ei0A:
7.5		 4jh4A-2ei0A:
19.47
4jh4B-2ei0A:
19.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JH5_A_FCNA202_1
(METALLOTHIOL
TRANSFERASE FOSB)		 2ei0 1,2-DIHYDROXYNAPHTHA
LENE DIOXYGENASE
(Pseudomonas
sp.
C18) 		5 / 11 HIS A 215
TYR A 256
GLU A 266
HIS A 152
ALA A 203
 FE2  A 399 ( 3.3A)
BP7  A 400 ( 4.7A)
FE2  A 399 ( 2.5A)
FE2  A 399 ( 3.4A)
BP7  A 401 ( 3.9A)
 0.49A 4jh5A-2ei0A:
7.5
4jh5B-2ei0A:
7.5		 4jh5A-2ei0A:
19.47
4jh5B-2ei0A:
19.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JH5_B_FCNB203_1
(METALLOTHIOL
TRANSFERASE FOSB)		 2ei0 1,2-DIHYDROXYNAPHTHA
LENE DIOXYGENASE
(Pseudomonas
sp.
C18) 		5 / 11 HIS A 152
ALA A 203
HIS A 215
TYR A 256
GLU A 266
 FE2  A 399 ( 3.4A)
BP7  A 401 ( 3.9A)
FE2  A 399 ( 3.3A)
BP7  A 400 ( 4.7A)
FE2  A 399 ( 2.5A)
 0.50A 4jh5A-2ei0A:
7.5
4jh5B-2ei0A:
7.5		 4jh5A-2ei0A:
19.47
4jh5B-2ei0A:
19.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JH6_A_FCNA202_1
(METALLOTHIOL
TRANSFERASE FOSB)		 2ei0 1,2-DIHYDROXYNAPHTHA
LENE DIOXYGENASE
(Pseudomonas
sp.
C18) 		5 / 10 HIS A 215
TYR A 256
GLU A 266
HIS A 152
ALA A 203
 FE2  A 399 ( 3.3A)
BP7  A 400 ( 4.7A)
FE2  A 399 ( 2.5A)
FE2  A 399 ( 3.4A)
BP7  A 401 ( 3.9A)
 0.51A 4jh6A-2ei0A:
7.6
4jh6B-2ei0A:
7.5		 4jh6A-2ei0A:
19.47
4jh6B-2ei0A:
19.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JH6_B_FCNB202_1
(METALLOTHIOL
TRANSFERASE FOSB)		 2ei0 1,2-DIHYDROXYNAPHTHA
LENE DIOXYGENASE
(Pseudomonas
sp.
C18) 		5 / 10 HIS A 152
ALA A 203
HIS A 215
TYR A 256
GLU A 266
 FE2  A 399 ( 3.4A)
BP7  A 401 ( 3.9A)
FE2  A 399 ( 3.3A)
BP7  A 400 ( 4.7A)
FE2  A 399 ( 2.5A)
 0.52A 4jh6A-2ei0A:
7.6
4jh6B-2ei0A:
7.5		 4jh6A-2ei0A:
19.47
4jh6B-2ei0A:
19.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JH8_A_FCNA204_1
(METALLOTHIOL
TRANSFERASE FOSB)		 2ei0 1,2-DIHYDROXYNAPHTHA
LENE DIOXYGENASE
(Pseudomonas
sp.
C18) 		5 / 10 HIS A 215
TYR A 256
GLU A 266
HIS A 152
ALA A 203
 FE2  A 399 ( 3.3A)
BP7  A 400 ( 4.7A)
FE2  A 399 ( 2.5A)
FE2  A 399 ( 3.4A)
BP7  A 401 ( 3.9A)
 0.50A 4jh8A-2ei0A:
7.5
4jh8B-2ei0A:
7.5		 4jh8A-2ei0A:
19.47
4jh8B-2ei0A:
19.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JH8_B_FCNB203_1
(METALLOTHIOL
TRANSFERASE FOSB)		 2ei0 1,2-DIHYDROXYNAPHTHA
LENE DIOXYGENASE
(Pseudomonas
sp.
C18) 		5 / 10 HIS A 152
ALA A 203
HIS A 215
TYR A 256
GLU A 266
 FE2  A 399 ( 3.4A)
BP7  A 401 ( 3.9A)
FE2  A 399 ( 3.3A)
BP7  A 400 ( 4.7A)
FE2  A 399 ( 2.5A)
 0.50A 4jh8A-2ei0A:
7.5
4jh8B-2ei0A:
7.5		 4jh8A-2ei0A:
19.47
4jh8B-2ei0A:
19.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z0F_B_DAHB98_0
(MELC
TYROSINASE)		 2ei0 1,2-DIHYDROXYNAPHTHA
LENE DIOXYGENASE
(Pseudomonas
sp.
C18) 		5 / 11 HIS A 215
ILE A 154
HIS A 152
ASN A 249
HIS A 247
 FE2  A 399 ( 3.3A)
BP7  A 401 (-4.3A)
FE2  A 399 ( 3.4A)
BP7  A 400 (-3.3A)
BP7  A 400 (-3.2A)
 1.41A 5z0fA-2ei0A:
undetectable
5z0fB-2ei0A:
undetectable		 5z0fA-2ei0A:
15.23
5z0fB-2ei0A:
11.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z0F_B_DAHB98_0
(MELC
TYROSINASE)		 2ei0 1,2-DIHYDROXYNAPHTHA
LENE DIOXYGENASE
(Pseudomonas
sp.
C18) 		5 / 11 HIS A 215
ILE A 154
HIS A 152
HIS A 247
ASN A 249
 FE2  A 399 ( 3.3A)
BP7  A 401 (-4.3A)
FE2  A 399 ( 3.4A)
BP7  A 400 (-3.2A)
BP7  A 400 (-3.3A)
 1.35A 5z0fA-2ei0A:
undetectable
5z0fB-2ei0A:
undetectable		 5z0fA-2ei0A:
15.23
5z0fB-2ei0A:
11.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z0G_B_DAHB98_0
(MELC
TYROSINASE)		 2ei0 1,2-DIHYDROXYNAPHTHA
LENE DIOXYGENASE
(Pseudomonas
sp.
C18) 		5 / 11 HIS A 215
ILE A 154
HIS A 152
ASN A 249
HIS A 247
 FE2  A 399 ( 3.3A)
BP7  A 401 (-4.3A)
FE2  A 399 ( 3.4A)
BP7  A 400 (-3.3A)
BP7  A 400 (-3.2A)
 1.42A 5z0gA-2ei0A:
undetectable
5z0gB-2ei0A:
undetectable		 5z0gA-2ei0A:
15.23
5z0gB-2ei0A:
11.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z0G_B_DAHB98_0
(MELC
TYROSINASE)		 2ei0 1,2-DIHYDROXYNAPHTHA
LENE DIOXYGENASE
(Pseudomonas
sp.
C18) 		5 / 11 HIS A 215
ILE A 154
HIS A 152
HIS A 247
ASN A 249
 FE2  A 399 ( 3.3A)
BP7  A 401 (-4.3A)
FE2  A 399 ( 3.4A)
BP7  A 400 (-3.2A)
BP7  A 400 (-3.3A)
 1.35A 5z0gA-2ei0A:
undetectable
5z0gB-2ei0A:
undetectable		 5z0gA-2ei0A:
15.23
5z0gB-2ei0A:
11.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z0I_B_DAHB98_0
(MELC
TYROSINASE)		 2ei0 1,2-DIHYDROXYNAPHTHA
LENE DIOXYGENASE
(Pseudomonas
sp.
C18) 		5 / 11 HIS A 215
ILE A 154
HIS A 152
ASN A 249
HIS A 247
 FE2  A 399 ( 3.3A)
BP7  A 401 (-4.3A)
FE2  A 399 ( 3.4A)
BP7  A 400 (-3.3A)
BP7  A 400 (-3.2A)
 1.37A 5z0iA-2ei0A:
undetectable
5z0iB-2ei0A:
undetectable		 5z0iA-2ei0A:
15.23
5z0iB-2ei0A:
11.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z0I_B_DAHB98_0
(MELC
TYROSINASE)		 2ei0 1,2-DIHYDROXYNAPHTHA
LENE DIOXYGENASE
(Pseudomonas
sp.
C18) 		5 / 11 HIS A 215
ILE A 154
HIS A 152
HIS A 247
ASN A 249
 FE2  A 399 ( 3.3A)
BP7  A 401 (-4.3A)
FE2  A 399 ( 3.4A)
BP7  A 400 (-3.2A)
BP7  A 400 (-3.3A)
 1.33A 5z0iA-2ei0A:
undetectable
5z0iB-2ei0A:
undetectable		 5z0iA-2ei0A:
15.23
5z0iB-2ei0A:
11.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z0M_B_DAHB98_0
(MELC
TYROSINASE)		 2ei0 1,2-DIHYDROXYNAPHTHA
LENE DIOXYGENASE
(Pseudomonas
sp.
C18) 		5 / 11 HIS A 215
ILE A 154
HIS A 152
ASN A 249
HIS A 247
 FE2  A 399 ( 3.3A)
BP7  A 401 (-4.3A)
FE2  A 399 ( 3.4A)
BP7  A 400 (-3.3A)
BP7  A 400 (-3.2A)
 1.26A 5z0mA-2ei0A:
undetectable
5z0mB-2ei0A:
undetectable		 5z0mA-2ei0A:
15.23
5z0mB-2ei0A:
11.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z0M_B_DAHB98_0
(MELC
TYROSINASE)		 2ei0 1,2-DIHYDROXYNAPHTHA
LENE DIOXYGENASE
(Pseudomonas
sp.
C18) 		5 / 11 HIS A 215
ILE A 154
HIS A 152
HIS A 247
ASN A 249
 FE2  A 399 ( 3.3A)
BP7  A 401 (-4.3A)
FE2  A 399 ( 3.4A)
BP7  A 400 (-3.2A)
BP7  A 400 (-3.3A)
 1.33A 5z0mA-2ei0A:
undetectable
5z0mB-2ei0A:
undetectable		 5z0mA-2ei0A:
15.23
5z0mB-2ei0A:
11.68