SIMILAR PATTERN OF AMINO ACIDS MAPPED TO 'BP6'


List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WKO_F_CUF154_0
(SUPEROXIDE DISMUTASE
[CU-ZN])		 1lkd BIPHENYL-2,3-DIOL
1,2-DIOXYGENASE
(Paraburkholderia
xenovorans) 		4 / 5 HIS A 146
HIS A 195
VAL A 148
HIS A 210
 FE2  A 500 ( 3.5A)
BP6  A 300 (-4.2A)
BP6  A 300 (-4.4A)
FE2  A 500 ( 3.5A)
 0.99A 2wkoF-1lkdA:
undetectable		 2wkoF-1lkdA:
16.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_C_SVRC505_2
(PHOSPHOLIPASE A2)		 1lkd BIPHENYL-2,3-DIOL
1,2-DIOXYGENASE
(Paraburkholderia
xenovorans) 		4 / 5 VAL A 274
VAL A 273
PHE A 187
ARG A 270
 None
None
BP6  A 300 (-4.3A)
None
 1.32A 3bjwH-1lkdA:
0.0		 3bjwH-1lkdA:
15.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_G_SVRG506_2
(PHOSPHOLIPASE A2)		 1lkd BIPHENYL-2,3-DIOL
1,2-DIOXYGENASE
(Paraburkholderia
xenovorans) 		4 / 5 VAL A 274
VAL A 273
PHE A 187
ARG A 270
 None
None
BP6  A 300 (-4.3A)
None
 1.33A 3bjwB-1lkdA:
0.0		 3bjwB-1lkdA:
15.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IR0_A_FCNA202_1
(METALLOTHIOL
TRANSFERASE FOSB 2)		 1lkd BIPHENYL-2,3-DIOL
1,2-DIOXYGENASE
(Paraburkholderia
xenovorans) 		5 / 11 HIS A 210
TYR A 250
GLU A 260
HIS A 146
ALA A 198
 FE2  A 500 ( 3.5A)
P6G  A 600 ( 3.7A)
FE2  A 500 ( 2.8A)
FE2  A 500 ( 3.5A)
BP6  A 300 ( 4.2A)
 0.57A 4ir0A-1lkdA:
7.2
4ir0B-1lkdA:
7.5		 4ir0A-1lkdA:
17.24
4ir0B-1lkdA:
17.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IR0_B_FCNB202_1
(METALLOTHIOL
TRANSFERASE FOSB 2)		 1lkd BIPHENYL-2,3-DIOL
1,2-DIOXYGENASE
(Paraburkholderia
xenovorans) 		5 / 11 HIS A 146
ALA A 198
HIS A 210
TYR A 250
GLU A 260
 FE2  A 500 ( 3.5A)
BP6  A 300 ( 4.2A)
FE2  A 500 ( 3.5A)
P6G  A 600 ( 3.7A)
FE2  A 500 ( 2.8A)
 0.51A 4ir0A-1lkdA:
7.2
4ir0B-1lkdA:
7.5		 4ir0A-1lkdA:
17.24
4ir0B-1lkdA:
17.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JD1_A_FCNA202_1
(METALLOTHIOL
TRANSFERASE FOSB 2)		 1lkd BIPHENYL-2,3-DIOL
1,2-DIOXYGENASE
(Paraburkholderia
xenovorans) 		5 / 12 HIS A 210
TYR A 250
GLU A 260
HIS A 146
ALA A 198
 FE2  A 500 ( 3.5A)
P6G  A 600 ( 3.7A)
FE2  A 500 ( 2.8A)
FE2  A 500 ( 3.5A)
BP6  A 300 ( 4.2A)
 0.52A 4jd1A-1lkdA:
7.3
4jd1B-1lkdA:
7.3		 4jd1A-1lkdA:
17.24
4jd1B-1lkdA:
17.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JD1_B_FCNB203_1
(METALLOTHIOL
TRANSFERASE FOSB 2)		 1lkd BIPHENYL-2,3-DIOL
1,2-DIOXYGENASE
(Paraburkholderia
xenovorans) 		5 / 12 HIS A 146
ALA A 198
HIS A 210
TYR A 250
GLU A 260
 FE2  A 500 ( 3.5A)
BP6  A 300 ( 4.2A)
FE2  A 500 ( 3.5A)
P6G  A 600 ( 3.7A)
FE2  A 500 ( 2.8A)
 0.63A 4jd1A-1lkdA:
7.3
4jd1B-1lkdA:
7.3		 4jd1A-1lkdA:
17.24
4jd1B-1lkdA:
17.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JH3_A_FCNA204_1
(METALLOTHIOL
TRANSFERASE FOSB)		 1lkd BIPHENYL-2,3-DIOL
1,2-DIOXYGENASE
(Paraburkholderia
xenovorans) 		5 / 12 HIS A 210
TYR A 250
GLU A 260
HIS A 146
ALA A 198
 FE2  A 500 ( 3.5A)
P6G  A 600 ( 3.7A)
FE2  A 500 ( 2.8A)
FE2  A 500 ( 3.5A)
BP6  A 300 ( 4.2A)
 0.50A 4jh3A-1lkdA:
3.8
4jh3B-1lkdA:
7.2		 4jh3A-1lkdA:
17.85
4jh3B-1lkdA:
17.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JH3_B_FCNB203_1
(METALLOTHIOL
TRANSFERASE FOSB)		 1lkd BIPHENYL-2,3-DIOL
1,2-DIOXYGENASE
(Paraburkholderia
xenovorans) 		5 / 11 HIS A 146
ALA A 198
HIS A 210
TYR A 250
GLU A 260
 FE2  A 500 ( 3.5A)
BP6  A 300 ( 4.2A)
FE2  A 500 ( 3.5A)
P6G  A 600 ( 3.7A)
FE2  A 500 ( 2.8A)
 0.48A 4jh3A-1lkdA:
3.8
4jh3B-1lkdA:
7.2		 4jh3A-1lkdA:
17.85
4jh3B-1lkdA:
17.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JH4_A_FCNA202_1
(METALLOTHIOL
TRANSFERASE FOSB)		 1lkd BIPHENYL-2,3-DIOL
1,2-DIOXYGENASE
(Paraburkholderia
xenovorans) 		5 / 11 HIS A 210
TYR A 250
GLU A 260
HIS A 146
ALA A 198
 FE2  A 500 ( 3.5A)
P6G  A 600 ( 3.7A)
FE2  A 500 ( 2.8A)
FE2  A 500 ( 3.5A)
BP6  A 300 ( 4.2A)
 0.43A 4jh4A-1lkdA:
7.1
4jh4B-1lkdA:
7.0		 4jh4A-1lkdA:
17.85
4jh4B-1lkdA:
17.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JH4_B_FCNB202_1
(METALLOTHIOL
TRANSFERASE FOSB)		 1lkd BIPHENYL-2,3-DIOL
1,2-DIOXYGENASE
(Paraburkholderia
xenovorans) 		5 / 11 HIS A 146
ALA A 198
HIS A 210
TYR A 250
GLU A 260
 FE2  A 500 ( 3.5A)
BP6  A 300 ( 4.2A)
FE2  A 500 ( 3.5A)
P6G  A 600 ( 3.7A)
FE2  A 500 ( 2.8A)
 0.44A 4jh4A-1lkdA:
7.1
4jh4B-1lkdA:
7.0		 4jh4A-1lkdA:
17.85
4jh4B-1lkdA:
17.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JH5_A_FCNA202_1
(METALLOTHIOL
TRANSFERASE FOSB)		 1lkd BIPHENYL-2,3-DIOL
1,2-DIOXYGENASE
(Paraburkholderia
xenovorans) 		5 / 11 HIS A 210
TYR A 250
GLU A 260
HIS A 146
ALA A 198
 FE2  A 500 ( 3.5A)
P6G  A 600 ( 3.7A)
FE2  A 500 ( 2.8A)
FE2  A 500 ( 3.5A)
BP6  A 300 ( 4.2A)
 0.47A 4jh5A-1lkdA:
7.1
4jh5B-1lkdA:
6.2		 4jh5A-1lkdA:
17.85
4jh5B-1lkdA:
17.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JH5_B_FCNB203_1
(METALLOTHIOL
TRANSFERASE FOSB)		 1lkd BIPHENYL-2,3-DIOL
1,2-DIOXYGENASE
(Paraburkholderia
xenovorans) 		5 / 11 HIS A 146
ALA A 198
HIS A 210
TYR A 250
GLU A 260
 FE2  A 500 ( 3.5A)
BP6  A 300 ( 4.2A)
FE2  A 500 ( 3.5A)
P6G  A 600 ( 3.7A)
FE2  A 500 ( 2.8A)
 0.48A 4jh5A-1lkdA:
7.1
4jh5B-1lkdA:
6.2		 4jh5A-1lkdA:
17.85
4jh5B-1lkdA:
17.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JH6_A_FCNA202_1
(METALLOTHIOL
TRANSFERASE FOSB)		 1lkd BIPHENYL-2,3-DIOL
1,2-DIOXYGENASE
(Paraburkholderia
xenovorans) 		5 / 10 HIS A 210
TYR A 250
GLU A 260
HIS A 146
ALA A 198
 FE2  A 500 ( 3.5A)
P6G  A 600 ( 3.7A)
FE2  A 500 ( 2.8A)
FE2  A 500 ( 3.5A)
BP6  A 300 ( 4.2A)
 0.49A 4jh6A-1lkdA:
7.1
4jh6B-1lkdA:
6.6		 4jh6A-1lkdA:
17.85
4jh6B-1lkdA:
17.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JH6_B_FCNB202_1
(METALLOTHIOL
TRANSFERASE FOSB)		 1lkd BIPHENYL-2,3-DIOL
1,2-DIOXYGENASE
(Paraburkholderia
xenovorans) 		5 / 10 HIS A 146
ALA A 198
HIS A 210
TYR A 250
GLU A 260
 FE2  A 500 ( 3.5A)
BP6  A 300 ( 4.2A)
FE2  A 500 ( 3.5A)
P6G  A 600 ( 3.7A)
FE2  A 500 ( 2.8A)
 0.50A 4jh6A-1lkdA:
7.1
4jh6B-1lkdA:
6.6		 4jh6A-1lkdA:
17.85
4jh6B-1lkdA:
17.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JH8_A_FCNA204_1
(METALLOTHIOL
TRANSFERASE FOSB)		 1lkd BIPHENYL-2,3-DIOL
1,2-DIOXYGENASE
(Paraburkholderia
xenovorans) 		5 / 10 HIS A 210
TYR A 250
GLU A 260
HIS A 146
ALA A 198
 FE2  A 500 ( 3.5A)
P6G  A 600 ( 3.7A)
FE2  A 500 ( 2.8A)
FE2  A 500 ( 3.5A)
BP6  A 300 ( 4.2A)
 0.48A 4jh8A-1lkdA:
7.1
4jh8B-1lkdA:
6.6		 4jh8A-1lkdA:
17.85
4jh8B-1lkdA:
17.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JH8_B_FCNB203_1
(METALLOTHIOL
TRANSFERASE FOSB)		 1lkd BIPHENYL-2,3-DIOL
1,2-DIOXYGENASE
(Paraburkholderia
xenovorans) 		5 / 10 HIS A 146
ALA A 198
HIS A 210
TYR A 250
GLU A 260
 FE2  A 500 ( 3.5A)
BP6  A 300 ( 4.2A)
FE2  A 500 ( 3.5A)
P6G  A 600 ( 3.7A)
FE2  A 500 ( 2.8A)
 0.48A 4jh8A-1lkdA:
7.1
4jh8B-1lkdA:
6.6		 4jh8A-1lkdA:
17.85
4jh8B-1lkdA:
17.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RP8_C_ASCC501_1
(ASCORBATE-SPECIFIC
PERMEASE IIC
COMPONENT ULAA)		 1lkd BIPHENYL-2,3-DIOL
1,2-DIOXYGENASE
(Paraburkholderia
xenovorans) 		3 / 3 SER A 248
TYR A 250
ASP A 244
 None
P6G  A 600 ( 3.7A)
BP6  A 300 ( 4.4A)
 0.83A 4rp8C-1lkdA:
0.0		 4rp8C-1lkdA:
20.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5K7U_A_SAMA601_1
(N6-ADENOSINE-METHYLT
RANSFERASE 70 KDA
SUBUNIT)		 1lkd BIPHENYL-2,3-DIOL
1,2-DIOXYGENASE
(Paraburkholderia
xenovorans) 		3 / 3 ASP A 244
ASN A 191
GLN A 142
 BP6  A 300 ( 4.4A)
None
None
 0.83A 5k7uA-1lkdA:
undetectable		 5k7uA-1lkdA:
22.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L5F_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA
TYPE-8,PROTEASOME
SUBUNIT BETA TYPE-5
PROTEASOME SUBUNIT
BETA
TYPE-6,PROTEASOME
SUBUNIT BETA
TYPE-1,PROTEASOME
SUBUNIT BETA
TYPE-6,PROTEASOME
SUBUNIT BETA
TYPE-1,PROTEASOME
SUBUNIT BETA TYPE-6)		 1lkd BIPHENYL-2,3-DIOL
1,2-DIOXYGENASE
(Paraburkholderia
xenovorans) 		4 / 8 SER A 287
SER A 236
MET A 175
SER A 281
 None
P6G  A 600 ( 4.0A)
P6G  A 600 (-4.4A)
BP6  A 300 ( 4.3A)
 1.12A 5l5fY-1lkdA:
0.0
5l5fZ-1lkdA:
undetectable		 5l5fY-1lkdA:
22.01
5l5fZ-1lkdA:
21.43